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Items: 1 to 50 of 434

1.

Reduced Glucose Variability With Glucose-Dependent Versus Glucose-Independent Therapies Despite Similar Glucose Control and Hypoglycemia Rates in a Randomized, Controlled Study of Older Patients With Type 2 Diabetes Mellitus.

Pratley RE, Rosenstock J, Heller SR, Sinclair A, Heine RJ, Kiljański J, Brusko CS, Duan R, Festa A.

J Diabetes Sci Technol. 2018 Nov;12(6):1184-1191. doi: 10.1177/1932296818776993. Epub 2018 Jun 12.

PMID:
29893144
2.

Glycaemic outcomes of an Individualized treatMent aPproach for oldER vulnerable patIents: A randomized, controlled stUdy in type 2 diabetes Mellitus (IMPERIUM).

Heller SR, Pratley RE, Sinclair A, Festa A, Kiljański J, Brusko CS, Duan R, Heine RJ.

Diabetes Obes Metab. 2018 Jan;20(1):148-156. doi: 10.1111/dom.13051. Epub 2017 Aug 8.

3.

Exenatide improves β-cell function up to 3 years of treatment in patients with type 2 diabetes: a randomised controlled trial.

van Raalte DH, Bunck MC, Smits MM, Hoekstra T, Cornér A, Diamant M, Eliasson B, Marja-RiittaTaskinen, Heine RJ, Smith U, HanneleYki-Järvinen, Mari A.

Eur J Endocrinol. 2016 Oct;175(4):345-52. doi: 10.1530/EJE-16-0286. Epub 2016 Jul 27.

PMID:
27466218
4.

Perspectives on Some Controversies in Cardiovascular Disease Risk Assessment in the Pharmaceutical Development of Glucose-Lowering Medications.

Hoogwerf BJ, Manner DH, Fu H, Moscarelli E, Gaydos BL, Heine RJ.

Diabetes Care. 2016 Aug;39 Suppl 2:S219-27. doi: 10.2337/dcS15-3025. Review.

PMID:
27440836
5.

Effect of diabetes on caregiver burden in an observational study of individuals with Alzheimer's disease.

Lebrec J, Ascher-Svanum H, Chen YF, Reed C, Kahle-Wrobleski K, Hake AM, Raskin J, Naderali E, Schuster D, Heine RJ, Kendall DM.

BMC Geriatr. 2016 May 3;16:93. doi: 10.1186/s12877-016-0264-8.

6.

Effectiveness of insulin therapy in people with Type 2 diabetes in the Hoorn Diabetes Care System.

Mast MR, Walraven I, Hoekstra T, Jansen AP, van der Heijden AA, Elders PJ, Heine RJ, Dekker JM, Nijpels G, Hugtenburg JG.

Diabet Med. 2016 Jun;33(6):794-802. doi: 10.1111/dme.13110. Epub 2016 Mar 25.

PMID:
26946450
7.

Time to insulin initiation and long-term effects of initiating insulin in people with type 2 diabetes mellitus: the Hoorn Diabetes Care System Cohort Study.

Mast R, Danielle Jansen AP, Walraven I, Rauh SP, van der Heijden AA, Heine RJ, Elders PJ, Dekker JM, Nijpels G, Hugtenburg JG.

Eur J Endocrinol. 2016 May;174(5):563-71. doi: 10.1530/EJE-15-1149. Epub 2016 Feb 2.

PMID:
26837781
8.

Effect of 3 Years of Treatment With Exenatide on Postprandial Glucagon Levels.

Smits MM, Bunck MC, Diamant M, Corner A, Eliasson B, Heine RJ, Smith U, Yki-Järvinen H, van Raalte DH.

Diabetes Care. 2016 Mar;39(3):e42-3. doi: 10.2337/dc15-2489. Epub 2015 Dec 30. No abstract available.

PMID:
26721816
9.

Erratum to: Associations Between Glycemic Control, Depressed Mood, Clinical Depression, and Diabetes Distress Before and After Insulin Initiation: An Exploratory, Post Hoc Analysis.

Ascher-Svanum H, Zagar A, Jiang D, Schuster D, Schmitt H, Dennehy EB, Kendall DM, Raskin J, Heine RJ.

Diabetes Ther. 2015 Sep;6(3):403. doi: 10.1007/s13300-015-0124-0. No abstract available.

10.

Associations Between Glycemic Control, Depressed Mood, Clinical Depression, and Diabetes Distress Before and After Insulin Initiation: An Exploratory, Post Hoc Analysis.

Ascher-Svanum H, Zagar A, Jiang D, Schuster D, Schmitt H, Dennehy EB, Kendall DM, Raskin J, Heine RJ.

Diabetes Ther. 2015 Sep;6(3):303-16. doi: 10.1007/s13300-015-0118-y. Epub 2015 Jul 10. Erratum in: Diabetes Ther. 2015 Sep;6(3):403.

11.

Cognitive and Functional Decline in Patients With Mild Alzheimer Dementia With or Without Comorbid Diabetes.

Ascher-Svanum H, Chen YF, Hake A, Kahle-Wrobleski K, Schuster D, Kendall D, Heine RJ.

Clin Ther. 2015 Jun 1;37(6):1195-205. doi: 10.1016/j.clinthera.2015.01.002. Epub 2015 Feb 9.

12.

Comment on Zhang et Al. Second-line agents for glycemic control for type 2 diabetes: are newer agents better? Diabetes Care 2014;37:1338-1345.

Bae J, Curtis BH, Kendall DM, Heine RJ.

Diabetes Care. 2014 Sep;37(9):e204. doi: 10.2337/dc14-1041. No abstract available.

PMID:
25147265
13.

Michaela Diamant, 11 April 1962-9 April 2014.

Heine RJ, Yki-Järvinen H, Kahn SE, van Raalte DH.

Diabetologia. 2014 Jul;57(7):1271-2. doi: 10.1007/s00125-014-3254-4. Epub 2014 May 6. No abstract available.

PMID:
24797287
14.

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility.

Guigas B, de Leeuw van Weenen JE, van Leeuwen N, Simonis-Bik AM, van Haeften TW, Nijpels G, Houwing-Duistermaat JJ, Beekman M, Deelen J, Havekes LM, Penninx BW, Vogelzangs N, van 't Riet E, Dehghan A, Hofman A, Witteman JC, Uitterlinden AG, Grarup N, Jørgensen T, Witte DR, Lauritzen T, Hansen T, Pedersen O, Hottenga J, Romijn JA, Diamant M, Kramer MH, Heine RJ, Willemsen G, Dekker JM, Eekhoff EM, Pijl H, de Geus EJ, Slagboom PE, 't Hart LM.

Diabet Med. 2014 Aug;31(8):1001-8. doi: 10.1111/dme.12464. Epub 2014 May 2.

PMID:
24724616
15.

Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events.

Fowkes FG, Murray GD, Butcher I, Folsom AR, Hirsch AT, Couper DJ, Debacker G, Kornitzer M, Newman AB, Sutton-Tyrrell KC, Cushman M, Lee AJ, Price JF, D'Agostino RB Sr, Murabito JM, Norman P, Masaki KH, Bouter LM, Heine RJ, Stehouwer CD, McDermott MM, Stoffers HE, Knottnerus JA, Ogren M, Hedblad B, Koenig W, Meisinger C, Cauley JA, Franco O, Hunink MG, Hofman A, Witteman JC, Criqui MH, Langer RD, Hiatt WR, Hamman RF; Ankle Brachial Index Collaboration.

Eur J Prev Cardiol. 2014 Mar;21(3):310-20. doi: 10.1177/2047487313516564. Epub 2013 Dec 23.

17.

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway.

't Hart LM, Fritsche A, Nijpels G, van Leeuwen N, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, Palmer CN, van Haeften TW, Herzberg-Schäfer SA, Simonis-Bik AM, Houwing-Duistermaat JJ, Helmer Q, Deelen J, Guigas B, Hansen T, Machicao F, Willemsen G, Heine RJ, Kramer MH, Holst JJ, de Koning EJ, Häring HU, Pedersen O, Groop L, de Geus EJ, Slagboom PE, Boomsma DI, Eekhoff EM, Pearson ER, Diamant M.

Diabetes. 2013 Sep;62(9):3275-81. doi: 10.2337/db13-0227. Epub 2013 May 14.

18.

Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?

van Raalte DH, Kwa KA, van Genugten RE, Tushuizen ME, Holst JJ, Deacon CF, Karemaker JM, Heine RJ, Mari A, Diamant M.

Metabolism. 2013 Apr;62(4):568-77. doi: 10.1016/j.metabol.2012.10.007. Epub 2012 Nov 17.

PMID:
23164480
19.

Screening for type 2 diabetes in a high-risk population: study design and feasibility of a population-based randomized controlled trial.

Klijs B, Otto SJ, Heine RJ, van der Graaf Y, Lous JJ, de Koning HJ.

BMC Public Health. 2012 Aug 17;12:671. doi: 10.1186/1471-2458-12-671.

20.

Effects of vildagliptin on postprandial markers of bone resorption and calcium homeostasis in recently diagnosed, well-controlled type 2 diabetes patients.

Bunck MC, Poelma M, Eekhoff EM, Schweizer A, Heine RJ, Nijpels G, Foley JE, Diamant M.

J Diabetes. 2012 Jun;4(2):181-5. doi: 10.1111/j.1753-0407.2011.00168.x.

PMID:
22051153
21.

Postprandial changes in the phospholipid composition of circulating microparticles are not associated with coagulation activation.

Tushuizen ME, Diamant M, Peypers EG, Hoek FJ, Heine RJ, Sturk A, Nieuwland R.

Thromb Res. 2012 Jul;130(1):115-21. doi: 10.1016/j.thromres.2011.09.003. Epub 2011 Oct 2.

22.

Effects of exenatide on measures of β-cell function after 3 years in metformin-treated patients with type 2 diabetes.

Bunck MC, Cornér A, Eliasson B, Heine RJ, Shaginian RM, Taskinen MR, Smith U, Yki-Järvinen H, Diamant M.

Diabetes Care. 2011 Sep;34(9):2041-7. doi: 10.2337/dc11-0291.

23.

Relationship between body mass index and mortality among Europeans.

Song X, Pitkäniemi J, Gao W, Heine RJ, Pyörälä K, Söderberg S, Stehouwer CD, Zethelius B, Tuomilehto J, Laatikainen T, Tabák AG, Qiao Q; DECODE Study Group.

Eur J Clin Nutr. 2012 Feb;66(2):156-65. doi: 10.1038/ejcn.2011.145. Epub 2011 Aug 10.

PMID:
21829217
24.

Does glucose variability influence the relationship between mean plasma glucose and HbA1c levels in type 1 and type 2 diabetic patients?

Kuenen JC, Borg R, Kuik DJ, Zheng H, Schoenfeld D, Diamant M, Nathan DM, Heine RJ; ADAG Study Group.

Diabetes Care. 2011 Aug;34(8):1843-7. doi: 10.2337/dc10-2217. Epub 2011 Jun 23.

25.

Beta cell function following 1 year vildagliptin or placebo treatment and after 12 week washout in drug-naive patients with type 2 diabetes and mild hyperglycaemia: a randomised controlled trial.

Foley JE, Bunck MC, Möller-Goede DL, Poelma M, Nijpels G, Eekhoff EM, Schweizer A, Heine RJ, Diamant M.

Diabetologia. 2011 Aug;54(8):1985-91. doi: 10.1007/s00125-011-2167-8. Epub 2011 May 6.

26.

The heritability of beta cell function parameters in a mixed meal test design.

Simonis-Bik AM, Boomsma DI, Dekker JM, Diamant M, de Geus EJ, 't Hart LM, Heine RJ, Kramer MH, Maassen JA, Mari A, Tura A, Willemsen G, Eekhoff EM.

Diabetologia. 2011 May;54(5):1043-51. doi: 10.1007/s00125-011-2060-5. Epub 2011 Feb 11.

27.

Systemic inflammation is linked to low arginine and high ADMA plasma levels resulting in an unfavourable NOS substrate-to-inhibitor ratio: the Hoorn Study.

van der Zwan LP, Scheffer PG, Dekker JM, Stehouwer CD, Heine RJ, Teerlink T.

Clin Sci (Lond). 2011 Jul;121(2):71-8. doi: 10.1042/CS20100595.

PMID:
21306304
28.

Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones.

Olthof MR, van Dijk AE, Deacon CF, Heine RJ, van Dam RM.

Nutr Metab (Lond). 2011 Feb 7;8:10. doi: 10.1186/1743-7075-8-10.

29.

Limited effect of screening for depression with written feedback in outpatients with diabetes mellitus: a randomised controlled trial.

Pouwer F, Tack CJ, Geelhoed-Duijvestijn PH, Bazelmans E, Beekman AT, Heine RJ, Snoek FJ.

Diabetologia. 2011 Apr;54(4):741-8. doi: 10.1007/s00125-010-2033-0. Epub 2011 Jan 11.

30.

Exenatide treatment did not affect bone mineral density despite body weight reduction in patients with type 2 diabetes.

Bunck MC, Eliasson B, Cornér A, Heine RJ, Shaginian RM, Taskinen MR, Yki-Järvinen H, Smith U, Diamant M.

Diabetes Obes Metab. 2011 Apr;13(4):374-7. doi: 10.1111/j.1463-1326.2010.01355.x.

PMID:
21205127
31.

HbA₁(c) and mean blood glucose show stronger associations with cardiovascular disease risk factors than do postprandial glycaemia or glucose variability in persons with diabetes: the A1C-Derived Average Glucose (ADAG) study.

Borg R, Kuenen JC, Carstensen B, Zheng H, Nathan DM, Heine RJ, Nerup J, Borch-Johnsen K, Witte DR; ADAG Study Group.

Diabetologia. 2011 Jan;54(1):69-72. doi: 10.1007/s00125-010-1918-2. Epub 2010 Oct 1.

32.

The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia.

Heni M, Ketterer C, Hart LM, Ranta F, van Haeften TW, Eekhoff EM, Dekker JM, Boomsma DI, Nijpels G, Kramer MH, Diamant M, Simonis-Bik AM, Heine RJ, de Geus EJ, Schäfer SA, Machicao F, Ullrich S, Thamer C, Stefan N, Staiger H, Häring HU, Fritsche A.

J Clin Endocrinol Metab. 2010 Dec;95(12):E479-84. doi: 10.1210/jc.2010-0860. Epub 2010 Sep 8.

PMID:
20826583
33.

Liver fat content in type 2 diabetes: relationship with hepatic perfusion and substrate metabolism.

Rijzewijk LJ, van der Meer RW, Lubberink M, Lamb HJ, Romijn JA, de Roos A, Twisk JW, Heine RJ, Lammertsma AA, Smit JW, Diamant M.

Diabetes. 2010 Nov;59(11):2747-54. doi: 10.2337/db09-1201. Epub 2010 Aug 6.

34.

Slightly elevated B-type natriuretic peptide levels in a non-heart failure range indicate a worse left ventricular diastolic function in individuals with, as compared with individuals without, type 2 diabetes: the Hoorn Study.

van den Hurk K, Alssema M, Kamp O, Henry RM, Stehouwer CD, Diamant M, Boomsma F, Heine RJ, Nijpels G, Paulus WJ, Dekker JM.

Eur J Heart Fail. 2010 Sep;12(9):958-65. doi: 10.1093/eurjhf/hfq119. Epub 2010 Jul 28.

35.

Diabetes-specific emotional distress mediates the association between depressive symptoms and glycaemic control in Type 1 and Type 2 diabetes.

van Bastelaar KM, Pouwer F, Geelhoed-Duijvestijn PH, Tack CJ, Bazelmans E, Beekman AT, Heine RJ, Snoek FJ.

Diabet Med. 2010 Jul;27(7):798-803. doi: 10.1111/j.1464-5491.2010.03025.x.

PMID:
20636961
36.

Effects of hepatic triglyceride content on myocardial metabolism in type 2 diabetes.

Rijzewijk LJ, Jonker JT, van der Meer RW, Lubberink M, de Jong HW, Romijn JA, Bax JJ, de Roos A, Heine RJ, Twisk JW, Windhorst AD, Lammertsma AA, Smit JW, Diamant M, Lamb HJ.

J Am Coll Cardiol. 2010 Jul 13;56(3):225-33. doi: 10.1016/j.jacc.2010.02.049.

37.

Plasma myeloperoxidase is inversely associated with endothelium-dependent vasodilation in elderly subjects with abnormal glucose metabolism.

van der Zwan LP, Teerlink T, Dekker JM, Henry RM, Stehouwer CD, Jakobs C, Heine RJ, Scheffer PG.

Metabolism. 2010 Dec;59(12):1723-9. doi: 10.1016/j.metabol.2010.04.012. Epub 2010 May 23.

PMID:
20580782
38.

Prevalence of comorbid depression is high in out-patients with Type 1 or Type 2 diabetes mellitus. Results from three out-patient clinics in the Netherlands.

Pouwer F, Geelhoed-Duijvestijn PH, Tack CJ, Bazelmans E, Beekman AJ, Heine RJ, Snoek FJ.

Diabet Med. 2010 Feb;27(2):217-24. doi: 10.1111/j.1464-5491.2009.02903.x.

PMID:
20546267
39.

The relationship between self-monitored blood glucose values and glycated haemoglobin in insulin-treated patients with Type 2 diabetes.

Sarwat S, Ilag LL, Carey MA, Shrom DS, Heine RJ.

Diabet Med. 2010 May;27(5):589-92. doi: 10.1111/j.1464-5491.2010.02955.x.

PMID:
20536957
40.

HbA1c is an independent predictor of non-fatal cardiovascular disease in a Caucasian population without diabetes: a 10-year follow-up of the Hoorn Study.

van 't Riet E, Rijkelijkhuizen JM, Alssema M, Nijpels G, Stehouwer CD, Heine RJ, Dekker JM.

Eur J Prev Cardiol. 2012 Feb;19(1):23-31. doi: 10.1097/HJR.0b013e32833b0932. Epub 2011 Jan 28.

PMID:
20517157
41.

One-year treatment with exenatide vs. insulin glargine: effects on postprandial glycemia, lipid profiles, and oxidative stress.

Bunck MC, Cornér A, Eliasson B, Heine RJ, Shaginian RM, Wu Y, Yan P, Smith U, Yki-Järvinen H, Diamant M, Taskinen MR.

Atherosclerosis. 2010 Sep;212(1):223-9. doi: 10.1016/j.atherosclerosis.2010.04.024. Epub 2010 Apr 29.

PMID:
20494360
42.

Diabetes, prediabetes and cancer mortality.

Zhou XH, Qiao Q, Zethelius B, Pyörälä K, Söderberg S, Pajak A, Stehouwer CD, Heine RJ, Jousilahti P, Ruotolo G, Nilsson PM, Calori G, Tuomilehto J; DECODE Study Group.

Diabetologia. 2010 Sep;53(9):1867-76. doi: 10.1007/s00125-010-1796-7. Epub 2010 May 21.

PMID:
20490448
43.

Associations between features of glucose exposure and A1C: the A1C-Derived Average Glucose (ADAG) study.

Borg R, Kuenen JC, Carstensen B, Zheng H, Nathan DM, Heine RJ, Nerup J, Borch-Johnsen K, Witte DR; ADAG Study Group.

Diabetes. 2010 Jul;59(7):1585-90. doi: 10.2337/db09-1774. Epub 2010 Apr 27.

44.

Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.

Bunck MC, Diamant M, Eliasson B, Cornér A, Shaginian RM, Heine RJ, Taskinen MR, Yki-Järvinen H, Smith U.

Diabetes Care. 2010 Aug;33(8):1734-7. doi: 10.2337/dc09-2361. Epub 2010 Apr 27.

45.

Real-life glycaemic profiles in non-diabetic individuals with low fasting glucose and normal HbA1c: the A1C-Derived Average Glucose (ADAG) study.

Borg R, Kuenen JC, Carstensen B, Zheng H, Nathan DM, Heine RJ, Nerup J, Borch-Johnsen K, Witte DR; ADAG Study Group.

Diabetologia. 2010 Aug;53(8):1608-11. doi: 10.1007/s00125-010-1741-9. Epub 2010 Apr 16.

46.

Hyperglycemia and oxidative stress strengthen the association between myeloperoxidase and blood pressure.

Van der Zwan LP, Scheffer PG, Dekker JM, Stehouwer CD, Heine RJ, Teerlink T.

Hypertension. 2010 Jun;55(6):1366-72. doi: 10.1161/HYPERTENSIONAHA.109.147231. Epub 2010 Apr 12.

PMID:
20385972
47.

Postprandial lipid and apolipoprotein responses following three consecutive meals associate with liver fat content in type 2 diabetes and the metabolic syndrome.

Tushuizen ME, Pouwels PJ, Bontemps S, Rustemeijer C, Matikainen N, Heine RJ, Taskinen MR, Diamant M.

Atherosclerosis. 2010 Jul;211(1):308-14. doi: 10.1016/j.atherosclerosis.2010.02.002. Epub 2010 Feb 10.

PMID:
20227695
48.

Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men.

van Raalte DH, Nofrate V, Bunck MC, van Iersel T, Elassaiss Schaap J, Nässander UK, Heine RJ, Mari A, Dokter WH, Diamant M.

Eur J Endocrinol. 2010 Apr;162(4):729-35. doi: 10.1530/EJE-09-1034. Epub 2010 Feb 2.

PMID:
20124412
49.

Survival as a function of HbA(1c) in people with type 2 diabetes: a retrospective cohort study.

Currie CJ, Peters JR, Tynan A, Evans M, Heine RJ, Bracco OL, Zagar T, Poole CD.

Lancet. 2010 Feb 6;375(9713):481-9. doi: 10.1016/S0140-6736(09)61969-3. Epub 2010 Jan 26.

PMID:
20110121
50.

The association between the -374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies.

Engelen L, Ferreira I, Gaens KH, Henry RM, Dekker JM, Nijpels G, Heine RJ, 't Hart LM, van Greevenbroek MM, van der Kallen CJ, Blaak EE, Feskens EJ, Ten Cate H, Stehouwer CD, Schalkwijk CG.

J Hypertens. 2010 Feb;28(2):285-93. doi: 10.1097/HJH.0b013e3283330931.

PMID:
20051912

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