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Items: 28

1.

MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices.

McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ.

Nat Methods. 2019 Jun 17. doi: 10.1038/s41592-019-0433-8. [Epub ahead of print]

PMID:
31209384
2.

Seagrass ecosystems reduce exposure to bacterial pathogens of humans, fishes, and invertebrates.

Lamb JB, van de Water JA, Bourne DG, Altier C, Hein MY, Fiorenza EA, Abu N, Jompa J, Harvell CD.

Science. 2017 Feb 17;355(6326):731-733. doi: 10.1126/science.aal1956.

PMID:
28209895
3.

A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.

Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS.

Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048.

4.

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism.

Saha S, Weber CA, Nousch M, Adame-Arana O, Hoege C, Hein MY, Osborne-Nishimura E, Mahamid J, Jahnel M, Jawerth L, Pozniakovski A, Eckmann CR, Jülicher F, Hyman AA.

Cell. 2016 Sep 8;166(6):1572-1584.e16. doi: 10.1016/j.cell.2016.08.006. Epub 2016 Sep 1.

5.

p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1.

Ma-Lauer Y, Carbajo-Lozoya J, Hein MY, Müller MA, Deng W, Lei J, Meyer B, Kusov Y, von Brunn B, Bairad DR, Hünten S, Drosten C, Hermeking H, Leonhardt H, Mann M, Hilgenfeld R, von Brunn A.

Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5192-201. doi: 10.1073/pnas.1603435113. Epub 2016 Aug 12.

6.

msVolcano: A flexible web application for visualizing quantitative proteomics data.

Singh S, Hein MY, Stewart AF.

Proteomics. 2016 Sep;16(18):2491-4. doi: 10.1002/pmic.201600167.

7.

The Perseus computational platform for comprehensive analysis of (prote)omics data.

Tyanova S, Temu T, Sinitcyn P, Carlson A, Hein MY, Geiger T, Mann M, Cox J.

Nat Methods. 2016 Sep;13(9):731-40. doi: 10.1038/nmeth.3901. Epub 2016 Jun 27.

PMID:
27348712
8.

A genome-wide resource for the analysis of protein localisation in Drosophila.

Sarov M, Barz C, Jambor H, Hein MY, Schmied C, Suchold D, Stender B, Janosch S, K J VV, Krishnan RT, Krishnamoorthy A, Ferreira IR, Ejsmont RK, Finkl K, Hasse S, Kämpfer P, Plewka N, Vinis E, Schloissnig S, Knust E, Hartenstein V, Mann M, Ramaswami M, VijayRaghavan K, Tomancak P, Schnorrer F.

Elife. 2016 Feb 20;5:e12068. doi: 10.7554/eLife.12068.

9.

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.

Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M.

Cell. 2015 Oct 22;163(3):712-23. doi: 10.1016/j.cell.2015.09.053. Epub 2015 Oct 22.

10.

mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.

Gebhardt A, Habjan M, Benda C, Meiler A, Haas DA, Hein MY, Mann A, Mann M, Habermann B, Pichlmair A.

Nat Commun. 2015 Sep 18;6:8192. doi: 10.1038/ncomms9192.

11.

A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation.

Patel A, Lee HO, Jawerth L, Maharana S, Jahnel M, Hein MY, Stoynov S, Mahamid J, Saha S, Franzmann TM, Pozniakovski A, Poser I, Maghelli N, Royer LA, Weigert M, Myers EW, Grill S, Drechsel D, Hyman AA, Alberti S.

Cell. 2015 Aug 27;162(5):1066-77. doi: 10.1016/j.cell.2015.07.047.

12.

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links.

Räschle M, Smeenk G, Hansen RK, Temu T, Oka Y, Hein MY, Nagaraj N, Long DT, Walter JC, Hofmann K, Storchova Z, Cox J, Bekker-Jensen S, Mailand N, Mann M.

Science. 2015 May 1;348(6234):1253671. doi: 10.1126/science.1253671. Epub 2015 Apr 30.

13.

Continuous T cell receptor signals maintain a functional regulatory T cell pool.

Vahl JC, Drees C, Heger K, Heink S, Fischer JC, Nedjic J, Ohkura N, Morikawa H, Poeck H, Schallenberg S, Rieß D, Hein MY, Buch T, Polic B, Schönle A, Zeiser R, Schmitt-Gräff A, Kretschmer K, Klein L, Korn T, Sakaguchi S, Schmidt-Supprian M.

Immunity. 2014 Nov 20;41(5):722-36. doi: 10.1016/j.immuni.2014.10.012. Epub 2014 Nov 6.

14.

Assessing baseline levels of coral health in a newly established marine protected area in a global scuba diving hotspot.

Hein MY, Lamb JB, Scott C, Willis BL.

Mar Environ Res. 2015 Feb;103:56-65. doi: 10.1016/j.marenvres.2014.11.008. Epub 2014 Nov 15.

PMID:
25460062
15.

Accurate protein complex retrieval by affinity enrichment mass spectrometry (AE-MS) rather than affinity purification mass spectrometry (AP-MS).

Keilhauer EC, Hein MY, Mann M.

Mol Cell Proteomics. 2015 Jan;14(1):120-35. doi: 10.1074/mcp.M114.041012. Epub 2014 Nov 2.

16.

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.

Phillips-Krawczak CA, Singla A, Starokadomskyy P, Deng Z, Osborne DG, Li H, Dick CJ, Gomez TS, Koenecke M, Zhang JS, Dai H, Sifuentes-Dominguez LF, Geng LN, Kaufmann SH, Hein MY, Wallis M, McGaughran J, Gecz J, Sluis Bv, Billadeau DD, Burstein E.

Mol Biol Cell. 2015 Jan 1;26(1):91-103. doi: 10.1091/mbc.E14-06-1073. Epub 2014 Oct 29.

17.

A "proteomic ruler" for protein copy number and concentration estimation without spike-in standards.

Wiśniewski JR, Hein MY, Cox J, Mann M.

Mol Cell Proteomics. 2014 Dec;13(12):3497-506. doi: 10.1074/mcp.M113.037309. Epub 2014 Sep 15.

18.

Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein-protein interactions.

Borner GH, Hein MY, Hirst J, Edgar JR, Mann M, Robinson MS.

Mol Biol Cell. 2014 Oct 15;25(20):3178-94. doi: 10.1091/mbc.E14-07-1198. Epub 2014 Aug 27.

19.

A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells.

Nández R, Balkin DM, Messa M, Liang L, Paradise S, Czapla H, Hein MY, Duncan JS, Mann M, De Camilli P.

Elife. 2014 Aug 8;3:e02975. doi: 10.7554/eLife.02975.

20.

The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix.

Wueseke O, Bunkenborg J, Hein MY, Zinke A, Viscardi V, Woodruff JB, Oegema K, Mann M, Andersen JS, Hyman AA.

Mol Biol Cell. 2014 Oct 1;25(19):2984-92. doi: 10.1091/mbc.E13-09-0514. Epub 2014 Aug 7.

21.

Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ.

Cox J, Hein MY, Luber CA, Paron I, Nagaraj N, Mann M.

Mol Cell Proteomics. 2014 Sep;13(9):2513-26. doi: 10.1074/mcp.M113.031591. Epub 2014 Jun 17.

22.

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.

Zanivan S, Maione F, Hein MY, Hernández-Fernaud JR, Ostasiewicz P, Giraudo E, Mann M.

Mol Cell Proteomics. 2013 Dec;12(12):3599-611. doi: 10.1074/mcp.M113.031344. Epub 2013 Aug 26.

23.

NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biology.

Vahl JC, Heger K, Knies N, Hein MY, Boon L, Yagita H, Polic B, Schmidt-Supprian M.

PLoS Biol. 2013;11(6):e1001589. doi: 10.1371/journal.pbio.1001589. Epub 2013 Jun 18.

24.

Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.

Hirst J, Borner GH, Edgar J, Hein MY, Mann M, Buchholz F, Antrobus R, Robinson MS.

Mol Biol Cell. 2013 Aug;24(16):2558-69. doi: 10.1091/mbc.E13-03-0170. Epub 2013 Jul 3.

25.

CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling.

Starokadomskyy P, Gluck N, Li H, Chen B, Wallis M, Maine GN, Mao X, Zaidi IW, Hein MY, McDonald FJ, Lenzner S, Zecha A, Ropers HH, Kuss AW, McGaughran J, Gecz J, Burstein E.

J Clin Invest. 2013 May;123(5):2244-56. doi: 10.1172/JCI66466. Epub 2013 Apr 8.

26.

A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.

Bassik MC, Kampmann M, Lebbink RJ, Wang S, Hein MY, Poser I, Weibezahn J, Horlbeck MA, Chen S, Mann M, Hyman AA, Leproust EM, McManus MT, Weissman JS.

Cell. 2013 Feb 14;152(4):909-22. doi: 10.1016/j.cell.2013.01.030. Epub 2013 Feb 8.

27.

Decoding human cytomegalovirus.

Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS.

Science. 2012 Nov 23;338(6110):1088-93. doi: 10.1126/science.1227919.

28.

Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions.

Frost A, Elgort MG, Brandman O, Ives C, Collins SR, Miller-Vedam L, Weibezahn J, Hein MY, Poser I, Mann M, Hyman AA, Weissman JS.

Cell. 2012 Jun 8;149(6):1339-52. doi: 10.1016/j.cell.2012.04.028.

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