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Best matches for Heinäniemi M[au]:

Role of the Keap1-Nrf2 pathway in cancer. Leinonen HM et al. Adv Cancer Res. (2014)

Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions. Niskanen H et al. Nucleic Acids Res. (2018)

Deregulation of the non-coding genome in leukemia. Teppo S et al. RNA Biol. (2017)

Search results

Items: 37

1.

Data-driven characterization of molecular phenotypes across heterogeneous sample collections.

Mehtonen J, Pölönen P, Häyrynen S, Dufva O, Lin J, Liuksiala T, Granberg K, Lohi O, Hautamäki V, Nykter M, Heinäniemi M.

Nucleic Acids Res. 2019 Jul 26;47(13):e76. doi: 10.1093/nar/gkz281.

2.

Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia.

Kuusanmäki H, Leppä AM, Pölönen P, Kontro M, Dufva O, Deb D, Yadav B, Brück O, Kumar A, Everaus H, Gjertsen BT, Heinäniemi M, Porkka K, Mustjoki S, Heckman CA.

Haematologica. 2019 Jul 11. pii: haematol.2018.214882. doi: 10.3324/haematol.2018.214882. [Epub ahead of print]

3.

Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies.

Pölönen P, Mehtonen J, Lin J, Liuksiala T, Häyrynen S, Teppo S, Mäkinen A, Kumar A, Malani D, Pohjolainen V, Porkka K, Heckman CA, May P, Hautamäki V, Granberg KJ, Lohi O, Nykter M, Heinäniemi M.

Cancer Res. 2019 May 15;79(10):2466-2479. doi: 10.1158/0008-5472.CAN-18-2970. Epub 2019 Apr 2.

PMID:
30940663
4.

HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development.

de Bock CE, Demeyer S, Degryse S, Verbeke D, Sweron B, Gielen O, Vandepoel R, Vicente C, Vanden Bempt M, Dagklis A, Geerdens E, Bornschein S, Gijsbers R, Soulier J, Meijerink JP, Heinäniemi M, Teppo S, Bouvy-Liivrand M, Lohi O, Radaelli E, Cools J.

Cancer Discov. 2018 May;8(5):616-631. doi: 10.1158/2159-8290.CD-17-0583. Epub 2018 Mar 1.

5.

Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions.

Niskanen H, Tuszynska I, Zaborowski R, Heinäniemi M, Ylä-Herttuala S, Wilczynski B, Kaikkonen MU.

Nucleic Acids Res. 2018 Feb 28;46(4):1724-1740. doi: 10.1093/nar/gkx1214.

6.

Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.

Bouvy-Liivrand M, Hernández de Sande A, Pölönen P, Mehtonen J, Vuorenmaa T, Niskanen H, Sinkkonen L, Kaikkonen MU, Heinäniemi M.

Nucleic Acids Res. 2017 Nov 16;45(20):12054. doi: 10.1093/nar/gkx909. No abstract available.

7.

Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture.

Bouvy-Liivrand M, Hernández de Sande A, Pölönen P, Mehtonen J, Vuorenmaa T, Niskanen H, Sinkkonen L, Kaikkonen MU, Heinäniemi M.

Nucleic Acids Res. 2017 Sep 29;45(17):9837-9849. doi: 10.1093/nar/gkx680.

8.

Aggravated Postinfarct Heart Failure in Type 2 Diabetes Is Associated with Impaired Mitophagy and Exaggerated Inflammasome Activation.

Durga Devi T, Babu M, Mäkinen P, Kaikkonen MU, Heinaniemi M, Laakso H, Ylä-Herttuala E, Rieppo L, Liimatainen T, Naumenko N, Tavi P, Ylä-Herttuala S.

Am J Pathol. 2017 Dec;187(12):2659-2673. doi: 10.1016/j.ajpath.2017.08.023. Epub 2017 Sep 19.

PMID:
28935571
9.

In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL.

Laukkanen S, Grönroos T, Pölönen P, Kuusanmäki H, Mehtonen J, Cloos J, Ossenkoppele G, Gjertsen B, Øystein B, Heckman C, Heinäniemi M, Kontro M, Lohi O.

Blood Cancer J. 2017 Sep 8;7(9):e604. doi: 10.1038/bcj.2017.87. No abstract available.

10.

Deregulation of the non-coding genome in leukemia.

Teppo S, Heinäniemi M, Lohi O.

RNA Biol. 2017 Jul 3;14(7):827-830. doi: 10.1080/15476286.2017.1312228. Epub 2017 Apr 7.

11.

Derailed regulatory network in childhood acute leukaemia.

Lohi O, Heinäniemi M.

Acta Paediatr. 2017 Mar;106(3):359-360. doi: 10.1111/apa.13714. No abstract available.

PMID:
28186373
12.

Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.

Grönroos T, Teppo S, Mehtonen J, Laukkanen S, Liuksiala T, Nykter M, Heinäniemi M, Lohi O.

Leuk Res. 2017 Mar;54:1-6. doi: 10.1016/j.leukres.2016.12.005. Epub 2016 Dec 26.

PMID:
28063378
13.

Genome-wide repression of eRNA and target gene loci by the ETV6-RUNX1 fusion in acute leukemia.

Teppo S, Laukkanen S, Liuksiala T, Nordlund J, Oittinen M, Teittinen K, Grönroos T, St-Onge P, Sinnett D, Syvänen AC, Nykter M, Viiri K, Heinäniemi M, Lohi O.

Genome Res. 2016 Nov;26(11):1468-1477. Epub 2016 Sep 12.

14.

Peroxisome proliferator-activated receptor-γ coactivator 1 α1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling.

Mutikainen M, Tuomainen T, Naumenko N, Huusko J, Smirin B, Laidinen S, Kokki K, Hynynen H, Ylä-Herttuala S, Heinäniemi M, Ruas JL, Tavi P.

J Physiol. 2016 Dec 1;594(23):7049-7071. doi: 10.1113/JP272847.

15.

Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots.

Heinäniemi M, Vuorenmaa T, Teppo S, Kaikkonen MU, Bouvy-Liivrand M, Mehtonen J, Niskanen H, Zachariadis V, Laukkanen S, Liuksiala T, Teittinen K, Lohi O.

Elife. 2016 Jul 19;5. pii: e13087. doi: 10.7554/eLife.13087.

16.

The Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPs.

Kuosmanen SM, Viitala S, Laitinen T, Peräkylä M, Pölönen P, Kansanen E, Leinonen H, Raju S, Wienecke-Baldacchino A, Närvänen A, Poso A, Heinäniemi M, Heikkinen S, Levonen AL.

Nucleic Acids Res. 2016 Feb 29;44(4):1760-75. doi: 10.1093/nar/gkw052. Epub 2016 Jan 29.

17.

Dysregulation of the Keap1-Nrf2 pathway in cancer.

Leinonen HM, Kansanen E, Pölönen P, Heinäniemi M, Levonen AL.

Biochem Soc Trans. 2015 Aug;43(4):645-9. doi: 10.1042/BST20150048. Epub 2015 Aug 3. Review.

PMID:
26551706
18.

Transcriptomics profiling of human SGBS adipogenesis.

Galhardo M, Sinkkonen L, Berninger P, Lin J, Sauter T, Heinäniemi M.

Genom Data. 2014 Aug 7;2:246-8. doi: 10.1016/j.gdata.2014.07.004. eCollection 2014 Dec.

19.

ChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes.

Galhardo M, Sinkkonen L, Berninger P, Lin J, Sauter T, Heinäniemi M.

Genom Data. 2014 Aug 6;2:230-6. doi: 10.1016/j.gdata.2014.07.002. eCollection 2014 Dec.

20.

Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network.

Pacheco MP, John E, Kaoma T, Heinäniemi M, Nicot N, Vallar L, Bueb JL, Sinkkonen L, Sauter T.

BMC Genomics. 2015 Oct 19;16:809. doi: 10.1186/s12864-015-1984-4.

21.

Prenatal metformin exposure in a maternal high fat diet mouse model alters the transcriptome and modifies the metabolic responses of the offspring.

Salomäki H, Heinäniemi M, Vähätalo LH, Ailanen L, Eerola K, Ruohonen ST, Pesonen U, Koulu M.

PLoS One. 2014 Dec 26;9(12):e115778. doi: 10.1371/journal.pone.0115778. eCollection 2014.

22.

Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson's disease.

Krishna A, Biryukov M, Trefois C, Antony PM, Hussong R, Lin J, Heinäniemi M, Glusman G, Köglsberger S, Boyd O, van den Berg BH, Linke D, Huang D, Wang K, Hood L, Tholey A, Schneider R, Galas DJ, Balling R, May P.

BMC Genomics. 2014 Dec 20;15:1154. doi: 10.1186/1471-2164-15-1154.

23.

Role of the Keap1-Nrf2 pathway in cancer.

Leinonen HM, Kansanen E, Pölönen P, Heinäniemi M, Levonen AL.

Adv Cancer Res. 2014;122:281-320. doi: 10.1016/B978-0-12-420117-0.00008-6. Review.

PMID:
24974185
24.

Combinatorial regulation of lipoprotein lipase by microRNAs during mouse adipogenesis.

Bouvy-Liivrand M, Heinäniemi M, John E, Schneider JG, Sauter T, Sinkkonen L.

RNA Biol. 2014;11(1):76-91. doi: 10.4161/rna.27655. Epub 2014 Jan 16.

25.

Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network.

Galhardo M, Sinkkonen L, Berninger P, Lin J, Sauter T, Heinäniemi M.

Nucleic Acids Res. 2014 Feb;42(3):1474-96. doi: 10.1093/nar/gkt989. Epub 2013 Nov 5.

26.

Overexpression of SNORD114-3 marks acute promyelocytic leukemia.

Liuksiala T, Teittinen KJ, Granberg K, Heinäniemi M, Annala M, Mäki M, Nykter M, Lohi O.

Leukemia. 2014 Jan;28(1):233-6. doi: 10.1038/leu.2013.250. Epub 2013 Aug 27. No abstract available.

PMID:
23979522
27.

Gene-pair expression signatures reveal lineage control.

Heinäniemi M, Nykter M, Kramer R, Wienecke-Baldacchino A, Sinkkonen L, Zhou JX, Kreisberg R, Kauffman SA, Huang S, Shmulevich I.

Nat Methods. 2013 Jun;10(6):577-83. doi: 10.1038/nmeth.2445. Epub 2013 Apr 21.

28.

Dataset integration identifies transcriptional regulation of microRNA genes by PPARγ in differentiating mouse 3T3-L1 adipocytes.

John E, Wienecke-Baldacchino A, Liivrand M, Heinäniemi M, Carlberg C, Sinkkonen L.

Nucleic Acids Res. 2012 May;40(10):4446-60. doi: 10.1093/nar/gks025. Epub 2012 Feb 7.

29.

Novel insights into the regulation of antioxidant-response-element-mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2.

Jyrkkänen HK, Kuosmanen S, Heinäniemi M, Laitinen H, Kansanen E, Mella-Aho E, Leinonen H, Ylä-Herttuala S, Levonen AL.

Biochem J. 2011 Dec 1;440(2):167-74. doi: 10.1042/BJ20110526.

PMID:
21812759
30.

Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells.

Thorne JL, Maguire O, Doig CL, Battaglia S, Fehr L, Sucheston LE, Heinaniemi M, O'Neill LP, McCabe CJ, Turner BM, Carlberg C, Campbell MJ.

Nucleic Acids Res. 2011 Mar;39(6):2045-56. doi: 10.1093/nar/gkq875. Epub 2010 Nov 17.

31.

Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis.

Lahnalampi M, Heinäniemi M, Sinkkonen L, Wabitsch M, Carlberg C.

PLoS One. 2010 Sep 27;5(9):e12991. doi: 10.1371/journal.pone.0012991.

32.

Cyclical regulation of the insulin-like growth factor binding protein 3 gene in response to 1alpha,25-dihydroxyvitamin D3.

Malinen M, Ryynänen J, Heinäniemi M, Väisänen S, Carlberg C.

Nucleic Acids Res. 2011 Jan;39(2):502-12. doi: 10.1093/nar/gkq820. Epub 2010 Sep 19.

33.

Profiling of promoter occupancy by PPARalpha in human hepatoma cells via ChIP-chip analysis.

van der Meer DL, Degenhardt T, Väisänen S, de Groot PJ, Heinäniemi M, de Vries SC, Müller M, Carlberg C, Kersten S.

Nucleic Acids Res. 2010 May;38(9):2839-50. doi: 10.1093/nar/gkq012. Epub 2010 Jan 27.

34.

Coordinate induction of PPAR alpha and SREBP2 in multifunctional protein 2 deficient mice.

Martens K, Ver Loren van Themaat E, van Batenburg MF, Heinäniemi M, Huyghe S, Van Hummelen P, Carlberg C, Van Veldhoven PP, Van Kampen A, Baes M.

Biochim Biophys Acta. 2008 Nov-Dec;1781(11-12):694-702. doi: 10.1016/j.bbalip.2008.07.010. Epub 2008 Aug 12.

PMID:
18773970
35.

Screening for PPAR Responsive Regulatory Modules in Cancer.

Heinäniemi M, Carlberg C.

PPAR Res. 2008;2008:749073. doi: 10.1155/2008/749073.

36.

DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.

Pendás-Franco N, García JM, Peña C, Valle N, Pálmer HG, Heinäniemi M, Carlberg C, Jiménez B, Bonilla F, Muñoz A, González-Sancho JM.

Oncogene. 2008 Jul 24;27(32):4467-77. doi: 10.1038/onc.2008.88. Epub 2008 Apr 14.

PMID:
18408752
37.

Meta-analysis of primary target genes of peroxisome proliferator-activated receptors.

Heinäniemi M, Uski JO, Degenhardt T, Carlberg C.

Genome Biol. 2007;8(7):R147.

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