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Items: 1 to 50 of 128

1.

Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.

Sullivan KM, Goldmuntz EA, Keyes-Elstein L, McSweeney PA, Pinckney A, Welch B, Mayes MD, Nash RA, Crofford LJ, Eggleston B, Castina S, Griffith LM, Goldstein JS, Wallace D, Craciunescu O, Khanna D, Folz RJ, Goldin J, St Clair EW, Seibold JR, Phillips K, Mineishi S, Simms RW, Ballen K, Wener MH, Georges GE, Heimfeld S, Hosing C, Forman S, Kafaja S, Silver RM, Griffing L, Storek J, LeClercq S, Brasington R, Csuka ME, Bredeson C, Keever-Taylor C, Domsic RT, Kahaleh MB, Medsger T, Furst DE; SCOT Study Investigators.

N Engl J Med. 2018 Jan 4;378(1):35-47.

2.

Preclinical Optimization of a CD20-specific Chimeric Antigen Receptor Vector and Culture Conditions.

Lee SY, Olsen P, Lee DH, Kenoyer AL, Budde LE, O'Steen S, Green DJ, Heimfeld S, Jensen MC, Riddell SR, Press OW, Till BG.

J Immunother. 2018 Jan;41(1):19-31. doi: 10.1097/CJI.0000000000000199.

PMID:
29176334
3.

Durable Molecular Remissions in Chronic Lymphocytic Leukemia Treated With CD19-Specific Chimeric Antigen Receptor-Modified T Cells After Failure of Ibrutinib.

Turtle CJ, Hay KA, Hanafi LA, Li D, Cherian S, Chen X, Wood B, Lozanski A, Byrd JC, Heimfeld S, Riddell SR, Maloney DG.

J Clin Oncol. 2017 Sep 10;35(26):3010-3020. doi: 10.1200/JCO.2017.72.8519. Epub 2017 Jul 17.

PMID:
28715249
4.

Manufacture of Autologous CD34+ Selected Grafts in the NIAID-Sponsored HALT-MS and SCOT Multicenter Clinical Trials for Autoimmune Diseases.

Keever-Taylor CA, Heimfeld S, Steinmiller KC, Nash RA, Sullivan KM, Czarniecki CW, Granderson TC, Goldstein JS, Griffith LM.

Biol Blood Marrow Transplant. 2017 Sep;23(9):1463-1472. doi: 10.1016/j.bbmt.2017.05.018. Epub 2017 Jun 30.

PMID:
28602891
5.

Notch-Expanded Murine Hematopoietic Stem and Progenitor Cells Mitigate Death from Lethal Radiation and Convey Immune Tolerance in Mismatched Recipients.

Milano F, Merriam F, Nicoud I, Li J, Gooley TA, Heimfeld S, Imren S, Delaney C.

Stem Cells Transl Med. 2017 Feb;6(2):566-575. doi: 10.5966/sctm.2016-0112. Epub 2016 Sep 13.

6.

Real Time Immunophenotyping of Leukocyte Subsets Early after Double Cord Blood Transplantation Predicts Graft Function.

Li J, Nicoud I, Blake J, Oliver D, Cox E, Heimfeld S, Milano F, Imren S, Delaney C.

Biol Blood Marrow Transplant. 2017 Mar;23(3):412-419. doi: 10.1016/j.bbmt.2016.12.625. Epub 2016 Dec 19.

7.

Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy.

Adair JE, Waters T, Haworth KG, Kubek SP, Trobridge GD, Hocum JD, Heimfeld S, Kiem HP.

Nat Commun. 2016 Oct 20;7:13173. doi: 10.1038/ncomms13173.

8.

Immunotherapy of non-Hodgkin's lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor-modified T cells.

Turtle CJ, Hanafi LA, Berger C, Hudecek M, Pender B, Robinson E, Hawkins R, Chaney C, Cherian S, Chen X, Soma L, Wood B, Li D, Heimfeld S, Riddell SR, Maloney DG.

Sci Transl Med. 2016 Sep 7;8(355):355ra116. doi: 10.1126/scitranslmed.aaf8621.

9.

Marrow grafts from HLA-identical siblings for severe aplastic anemia: does limiting the number of transplanted marrow cells reduce the risk of chronic GvHD?

Gallo S, Woolfrey AE, Burroughs LM, Storer BE, Flowers ME, Hari P, Pulsipher MA, Heimfeld S, Kiem HP, Sandmaier BM, Storb R.

Bone Marrow Transplant. 2016 Dec;51(12):1573-1578. doi: 10.1038/bmt.2016.198. Epub 2016 Aug 1.

10.

CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients.

Turtle CJ, Hanafi LA, Berger C, Gooley TA, Cherian S, Hudecek M, Sommermeyer D, Melville K, Pender B, Budiarto TM, Robinson E, Steevens NN, Chaney C, Soma L, Chen X, Yeung C, Wood B, Li D, Cao J, Heimfeld S, Jensen MC, Riddell SR, Maloney DG.

J Clin Invest. 2016 Jun 1;126(6):2123-38. doi: 10.1172/JCI85309. Epub 2016 Apr 25.

11.

A Distributed Network for Intensive Longitudinal Monitoring in Metastatic Triple-Negative Breast Cancer.

Blau CA, Ramirez AB, Blau S, Pritchard CC, Dorschner MO, Schmechel SC, Martins TJ, Mahen EM, Burton KA, Komashko VM, Radenbaugh AJ, Dougherty K, Thomas A, Miller CP, Annis J, Fromm JR, Song C, Chang E, Howard K, Austin S, Schmidt RA, Linenberger ML, Becker PS, Senecal FM, Mecham BH, Lee SI, Madan A, Ronen R, Dutkowski J, Heimfeld S, Wood BL, Stilwell JL, Kaldjian EP, Haussler D, Zhu J.

J Natl Compr Canc Netw. 2016 Jan;14(1):8-17.

12.

Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts.

Bleakley M, Heimfeld S, Loeb KR, Jones LA, Chaney C, Seropian S, Gooley TA, Sommermeyer F, Riddell SR, Shlomchik WD.

J Clin Invest. 2015 Jul 1;125(7):2677-89. doi: 10.1172/JCI81229. Epub 2015 Jun 8.

13.

Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemia.

Qu X, Davison J, Du L, Storer B, Stirewalt DL, Heimfeld S, Estey E, Appelbaum FR, Fang M.

Epigenetics. 2015;10(6):526-35. doi: 10.1080/15592294.2015.1048060.

14.

Association of fludarabine pharmacokinetic/dynamic biomarkers with donor chimerism in nonmyeloablative HCT recipients.

McCune JS, Mager DE, Bemer MJ, Sandmaier BM, Storer BE, Heimfeld S.

Cancer Chemother Pharmacol. 2015 Jul;76(1):85-96. doi: 10.1007/s00280-015-2768-x. Epub 2015 May 17.

15.

Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells.

Pollack SM, Jones RL, Farrar EA, Lai IP, Lee SM, Cao J, Pillarisetty VG, Hoch BL, Gullett A, Bleakley M, Conrad EU 3rd, Eary JF, Shibuya KC, Warren EH, Carstens JN, Heimfeld S, Riddell SR, Yee C.

J Immunother Cancer. 2014 Oct 14;2(1):36. doi: 10.1186/s40425-014-0036-y. eCollection 2014.

16.

MIR144 and MIR451 regulate human erythropoiesis via RAB14.

Kim M, Tan YS, Cheng WC, Kingsbury TJ, Heimfeld S, Civin CI.

Br J Haematol. 2015 Feb;168(4):583-97. doi: 10.1111/bjh.13164. Epub 2014 Oct 14.

17.

Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells.

Bleakley M, Heimfeld S, Jones LA, Turtle C, Krause D, Riddell SR, Shlomchik W.

Biol Blood Marrow Transplant. 2014 May;20(5):705-16. doi: 10.1016/j.bbmt.2014.01.032. Epub 2014 Feb 11.

18.

Hematopoietic SCT with cryopreserved grafts: adverse reactions after transplantation and cryoprotectant removal before infusion.

Shu Z, Heimfeld S, Gao D.

Bone Marrow Transplant. 2014 Apr;49(4):469-76. doi: 10.1038/bmt.2013.152. Epub 2013 Sep 30. Review.

19.

Developmental fate and cellular maturity encoded in human regulatory DNA landscapes.

Stergachis AB, Neph S, Reynolds A, Humbert R, Miller B, Paige SL, Vernot B, Cheng JB, Thurman RE, Sandstrom R, Haugen E, Heimfeld S, Murry CE, Akey JM, Stamatoyannopoulos JA.

Cell. 2013 Aug 15;154(4):888-903. doi: 10.1016/j.cell.2013.07.020.

20.

MiR-27a functions as a tumor suppressor in acute leukemia by regulating 14-3-3θ.

Scheibner KA, Teaboldt B, Hauer MC, Chen X, Cherukuri S, Guo Y, Kelley SM, Liu Z, Baer MR, Heimfeld S, Civin CI.

PLoS One. 2012;7(12):e50895. doi: 10.1371/journal.pone.0050895. Epub 2012 Dec 7.

21.

Correlation of infused CD3+CD8+ cells with single-donor dominance after double-unit cord blood transplantation.

Milano F, Heimfeld S, Gooley T, Jinneman J, Nicoud I, Delaney C.

Biol Blood Marrow Transplant. 2013 Jan;19(1):156-60. doi: 10.1016/j.bbmt.2012.09.004. Epub 2012 Sep 16.

22.

Systematic localization of common disease-associated variation in regulatory DNA.

Maurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, Wang H, Reynolds AP, Sandstrom R, Qu H, Brody J, Shafer A, Neri F, Lee K, Kutyavin T, Stehling-Sun S, Johnson AK, Canfield TK, Giste E, Diegel M, Bates D, Hansen RS, Neph S, Sabo PJ, Heimfeld S, Raubitschek A, Ziegler S, Cotsapas C, Sotoodehnia N, Glass I, Sunyaev SR, Kaul R, Stamatoyannopoulos JA.

Science. 2012 Sep 7;337(6099):1190-5. doi: 10.1126/science.1222794. Epub 2012 Sep 5.

23.

Improved immunomagnetic enrichment of CD34(+) cells from umbilical cord blood using the CliniMACS cell separation system.

Blake JM, Nicoud IB, Weber D, Voorhies H, Guthrie KA, Heimfeld S, Delaney C.

Cytotherapy. 2012 Aug;14(7):818-22. doi: 10.3109/14653249.2012.681040. Epub 2012 May 2.

24.

Early CD3 peripheral blood chimerism predicts the long-term engrafting unit following myeloablative double-cord blood transplantation.

Newell LF, Milano F, Nicoud IB, Pereira S, Gooley TA, Heimfeld S, Delaney C.

Biol Blood Marrow Transplant. 2012 Aug;18(8):1243-9. doi: 10.1016/j.bbmt.2012.01.014. Epub 2012 Feb 8.

25.

A pilot pharmacologic biomarker study of busulfan and fludarabine in hematopoietic cell transplant recipients.

McCune JS, Woodahl EL, Furlong T, Storer B, Wang J, Heimfeld S, Deeg HJ, O'Donnell PV.

Cancer Chemother Pharmacol. 2012 Jan;69(1):263-72. doi: 10.1007/s00280-011-1736-3. Epub 2011 Sep 11.

26.

Innate signals overcome acquired TCR signaling pathway regulation and govern the fate of human CD161(hi) CD8α⁺ semi-invariant T cells.

Turtle CJ, Delrow J, Joslyn RC, Swanson HM, Basom R, Tabellini L, Delaney C, Heimfeld S, Hansen JA, Riddell SR.

Blood. 2011 Sep 8;118(10):2752-62. doi: 10.1182/blood-2011-02-334698. Epub 2011 Jul 25.

27.

Limiting the daily total nucleated cell dose of cryopreserved peripheral blood stem cell products for autologous transplantation improves infusion-related safety with no adverse impact on hematopoietic engraftment.

Khera N, Jinneman J, Storer BE, Heimfeld S, O'Meara MM, Chauncey TR, Lee SJ, Linenberger M.

Biol Blood Marrow Transplant. 2012 Feb;18(2):220-8. doi: 10.1016/j.bbmt.2011.06.003. Epub 2011 Jun 15.

28.

A dilution-filtration system for removing cryoprotective agents.

Zhou X, Liu Z, Shu Z, Ding W, Du P, Chung J, Liu C, Heimfeld S, Gao D.

J Biomech Eng. 2011 Feb;133(2):021007. doi: 10.1115/1.4003317.

PMID:
21280879
29.

Identification of radiation-induced expression changes in nonimmortalized human T cells.

Pogosova-Agadjanyan EL, Fan W, Georges GE, Schwartz JL, Kepler CM, Lee H, Suchanek AL, Cronk MR, Brumbaugh A, Engel JH, Yukawa M, Zhao LP, Heimfeld S, Stirewalt DL.

Radiat Res. 2011 Feb;175(2):172-84. Epub 2010 Nov 17.

30.

Theoretical and experimental analyses of optimal experimental design for determination of hydraulic conductivity of cell membrane.

Zhou X, Gao F, Shu Z, Chung JH, Heimfeld S, Gao D.

Biopreserv Biobank. 2010 Sep;8(3):147-52. doi: 10.1089/bio.2010.0011.

PMID:
24836483
31.

A steady-state mass transfer model of removing CPAs from cryopreserved blood with hollow fiber modules.

Ding W, Zhou X, Heimfeld S, Reems JA, Gao D.

J Biomech Eng. 2010 Jan;132(1):011002. doi: 10.1115/1.4000110.

32.

A preclinical model of double- versus single-unit unrelated cord blood transplantation.

Georges GE, Lesnikov V, Baran SW, Aragon A, Lesnikova M, Jordan R, Laura Yang YJ, Yunusov MY, Zellmer E, Heimfeld S, Venkataraman GM, Harkey MA, Graves SS, Storb R, Storer BE, Nash RA.

Biol Blood Marrow Transplant. 2010 Aug;16(8):1090-8. doi: 10.1016/j.bbmt.2010.03.010. Epub 2010 Mar 18.

33.

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.

Delaney C, Heimfeld S, Brashem-Stein C, Voorhies H, Manger RL, Bernstein ID.

Nat Med. 2010 Feb;16(2):232-6. doi: 10.1038/nm.2080. Epub 2010 Jan 17.

34.

Developments in clinical cell therapy.

Stroncek D, Berlyne D, Fox B, Gee A, Heimfeld S, Lindblad R, Loper K, McKenna D Jr, Rooney C, Sabatino M, Wagner E, Whiteside T, Wood D, Heath-Mondoro T.

Cytotherapy. 2010 May;12(3):425-8. doi: 10.3109/14653240903511952.

35.

Donor statin treatment protects against severe acute graft-versus-host disease after related allogeneic hematopoietic cell transplantation.

Rotta M, Storer BE, Storb RF, Martin PJ, Heimfeld S, Peffer A, Maloney DG, Deeg HJ, Sandmaier BM, Appelbaum FR, Mielcarek M.

Blood. 2010 Feb 11;115(6):1288-95. doi: 10.1182/blood-2009-08-240358. Epub 2009 Dec 4.

36.

Development of a reliable low-cost controlled cooling rate instrument for the cryopreservation of hematopoietic stem cells.

Shu Z, Kang X, Chen H, Zhou X, Purtteman J, Yadock D, Heimfeld S, Gao D.

Cytotherapy. 2010 Apr;12(2):161-9. doi: 10.3109/14653240903377037.

37.

Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.

Gutman JA, Turtle CJ, Manley TJ, Heimfeld S, Bernstein ID, Riddell SR, Delaney C.

Blood. 2010 Jan 28;115(4):757-65. doi: 10.1182/blood-2009-07-228999. Epub 2009 Oct 12.

38.

Improved post-thaw recovery of peripheral blood stem/progenitor cells using a novel intracellular-like cryopreservation solution.

Clarke DM, Yadock DJ, Nicoud IB, Mathew AJ, Heimfeld S.

Cytotherapy. 2009;11(4):472-9. doi: 10.1080/14653240902887242.

39.

Cryopreservation of Peripheral Blood Stem Cells Using a Box-in-Box Cooling Device.

Zhou X, Kang X, Shu Z, Chen H, Ding W, Du P, Yadock D, Chi Liu C, Chung JH, Heimfeld S, Gao D.

Biopreserv Biobank. 2009 Jun;7(2):107-14. doi: 10.1089/bio.2009.0005.

PMID:
24835682
40.

Intracellular disposition of fludarabine triphosphate in human natural killer cells.

Woodahl EL, Wang J, Heimfeld S, Sandmaier BM, McCune JS.

Cancer Chemother Pharmacol. 2009 Apr;63(5):959-64. doi: 10.1007/s00280-008-0829-0. Epub 2008 Sep 10.

41.

Decreased IRF8 expression found in aging hematopoietic progenitor/stem cells.

Stirewalt DL, Choi YE, Sharpless NE, Pogosova-Agadjanyan EL, Cronk MR, Yukawa M, Larson EB, Wood BL, Appelbaum FR, Radich JP, Heimfeld S.

Leukemia. 2009 Feb;23(2):391-3. doi: 10.1038/leu.2008.176. Epub 2008 Jul 3. No abstract available. Erratum in: Leukemia. 2009 Feb;23(2):430.

42.

An Application of Stream Imaging Technique in the Study of Osmotic Behaviors of Multiple Cells.

Chen HH, Lin EH, Heimfeld S, Gao D.

Cell Preserv Technol. 2008 Jun 1;6(2):125-132.

43.

A novel phenotypic method to determine fludarabine triphosphate accumulation in T-lymphocytes from hematopoietic cell transplantation patients.

Woodahl EL, Wang J, Heimfeld S, Sandmaier BM, O'Donnell PV, Phillips B, Risler L, Blough DK, McCune JS.

Cancer Chemother Pharmacol. 2009 Feb;63(3):391-401. doi: 10.1007/s00280-008-0748-0. Epub 2008 Apr 9.

PMID:
18398611
44.

Imatinib inhibition of fludarabine uptake in T-lymphocytes.

Woodahl EL, Wang J, Heimfeld S, Ren AG, McCune JS.

Cancer Chemother Pharmacol. 2008 Sep;62(4):735-9. Epub 2007 Nov 15.

PMID:
18004569
45.

Identification of genes with abnormal expression changes in acute myeloid leukemia.

Stirewalt DL, Meshinchi S, Kopecky KJ, Fan W, Pogosova-Agadjanyan EL, Engel JH, Cronk MR, Dorcy KS, McQuary AR, Hockenbery D, Wood B, Heimfeld S, Radich JP.

Genes Chromosomes Cancer. 2008 Jan;47(1):8-20.

PMID:
17910043
46.

Development of a microfluidic device for determination of cell osmotic behavior and membrane transport properties.

Chen HH, Purtteman JJ, Heimfeld S, Folch A, Gao D.

Cryobiology. 2007 Dec;55(3):200-9. Epub 2007 Aug 24.

PMID:
17889847
47.

CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control.

Georgantas RW 3rd, Hildreth R, Morisot S, Alder J, Liu CG, Heimfeld S, Calin GA, Croce CM, Civin CI.

Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2750-5. Epub 2007 Feb 9.

48.

Connective tissue growth factor (CTGF) expression and outcome in adult patients with acute lymphoblastic leukemia.

Sala-Torra O, Gundacker HM, Stirewalt DL, Ladne PA, Pogosova-Agadjanyan EL, Slovak ML, Willman CL, Heimfeld S, Boldt DH, Radich JP.

Blood. 2007 Apr 1;109(7):3080-3.

49.

Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen.

Deeg HJ, Storer BE, Boeckh M, Martin PJ, McCune JS, Myerson D, Heimfeld S, Flowers ME, Anasetti C, Doney KC, Hansen JA, Kiem HP, Nash RA, O'Donnell PV, Radich JP, Sandmaier BM, Scott BL, Sorror ML, Warren EH, Witherspoon RP, Woolfrey A, Appelbaum FR, Storb R.

Biol Blood Marrow Transplant. 2006 May;12(5):573-84.

50.

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI.

Stem Cells. 2006 Apr;24(4):876-88. Epub 2006 Mar 2.

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