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Items: 44


Identification of Tn Antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies.

Matsumoto Y, Kudelka MR, Hanes MS, Lehoux S, Dutta S, Jones MB, Stackhouse KA, Cervoni GE, Heimburg-Molinaro J, Smith DF, Ju T, Chaikof EL, Cummings RD.

Glycobiology. 2019 Nov 19. pii: cwz095. doi: 10.1093/glycob/cwz095. [Epub ahead of print]


Novel Reversible Fluorescent Glycan Linker for Functional Glycomics.

Wei M, McKitrick TR, Mehta AY, Gao C, Jia N, McQuillan AM, Heimburg-Molinaro J, Sun L, Cummings RD.

Bioconjug Chem. 2019 Nov 20;30(11):2897-2908. doi: 10.1021/acs.bioconjchem.9b00613. Epub 2019 Oct 25.


Natural and Synthetic Sialylated Glycan Microarrays and Their Applications.

McQuillan AM, Byrd-Leotis L, Heimburg-Molinaro J, Cummings RD.

Front Mol Biosci. 2019 Sep 13;6:88. doi: 10.3389/fmolb.2019.00088. eCollection 2019. Review.


Antigenic Pressure on H3N2 Influenza Virus Drift Strains Imposes Constraints on Binding to Sialylated Receptors but Not Phosphorylated Glycans.

Byrd-Leotis L, Gao C, Jia N, Mehta AY, Trost J, Cummings SF, Heimburg-Molinaro J, Cummings RD, Steinhauer DA.

J Virol. 2019 Oct 29;93(22). pii: e01178-19. doi: 10.1128/JVI.01178-19. Print 2019 Nov 15.


Influenza binds phosphorylated glycans from human lung.

Byrd-Leotis L, Jia N, Dutta S, Trost JF, Gao C, Cummings SF, Braulke T, Müller-Loennies S, Heimburg-Molinaro J, Steinhauer DA, Cummings RD.

Sci Adv. 2019 Feb 13;5(2):eaav2554. doi: 10.1126/sciadv.aav2554. eCollection 2019 Feb.


Molecular cloning, expression, and characterization of UDP N-acetyl-α-d-galactosamine: Polypeptide N-acetylgalactosaminyltransferase 4 from Cryptosporidium parvum.

DeCicco RePass MA, Bhat N, Heimburg-Molinaro J, Bunnell S, Cummings RD, Ward HD.

Mol Biochem Parasitol. 2018 Apr;221:56-65. doi: 10.1016/j.molbiopara.2018.03.002. Epub 2018 Mar 23.


A library of chemically defined human N-glycans synthesized from microbial oligosaccharide precursors.

Hamilton BS, Wilson JD, Shumakovich MA, Fisher AC, Brooks JC, Pontes A, Naran R, Heiss C, Gao C, Kardish R, Heimburg-Molinaro J, Azadi P, Cummings RD, Merritt JH, DeLisa MP.

Sci Rep. 2017 Nov 21;7(1):15907. doi: 10.1038/s41598-017-15891-8.


Glycan microarrays of fluorescently-tagged natural glycans.

Song X, Heimburg-Molinaro J, Smith DF, Cummings RD.

Glycoconj J. 2015 Oct;32(7):465-73. doi: 10.1007/s10719-015-9584-8. Epub 2015 Apr 16. Review.


Simple sugars to complex disease--mucin-type O-glycans in cancer.

Kudelka MR, Ju T, Heimburg-Molinaro J, Cummings RD.

Adv Cancer Res. 2015;126:53-135. doi: 10.1016/bs.acr.2014.11.002. Epub 2015 Feb 7. Review.


Intact reducing glycan promotes the specific immune response to lacto-N-neotetraose-BSA neoglycoconjugates.

Prasanphanich NS, Song X, Heimburg-Molinaro J, Luyai AE, Lasanajak Y, Cutler CE, Smith DF, Cummings RD.

Bioconjug Chem. 2015 Mar 18;26(3):559-71. doi: 10.1021/acs.bioconjchem.5b00036. Epub 2015 Feb 25.


Examining galectin binding specificity using glycan microarrays.

Arthur CM, Rodrigues LC, Baruffi MD, Sullivan HC, Heimburg-Molinaro J, Smith DF, Cummings RD, Stowell SR.

Methods Mol Biol. 2015;1207:115-31. doi: 10.1007/978-1-4939-1396-1_8.


Deciphering the glycogenome of schistosomes.

Mickum ML, Prasanphanich NS, Heimburg-Molinaro J, Leon KE, Cummings RD.

Front Genet. 2014 Aug 5;5:262. doi: 10.3389/fgene.2014.00262. eCollection 2014. Review.


Shotgun glycomics of pig lung identifies natural endogenous receptors for influenza viruses.

Byrd-Leotis L, Liu R, Bradley KC, Lasanajak Y, Cummings SF, Song X, Heimburg-Molinaro J, Galloway SE, Culhane MR, Smith DF, Steinhauer DA, Cummings RD.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2241-50. doi: 10.1073/pnas.1323162111. Epub 2014 May 19.


Microbial glycan microarrays define key features of host-microbial interactions.

Stowell SR, Arthur CM, McBride R, Berger O, Razi N, Heimburg-Molinaro J, Rodrigues LC, Gourdine JP, Noll AJ, von Gunten S, Smith DF, Knirel YA, Paulson JC, Cummings RD.

Nat Chem Biol. 2014 Jun;10(6):470-6. doi: 10.1038/nchembio.1525. Epub 2014 May 11.


Differential expression of anti-glycan antibodies in schistosome-infected humans, rhesus monkeys and mice.

Luyai AE, Heimburg-Molinaro J, Prasanphanich NS, Mickum ML, Lasanajak Y, Song X, Nyame AK, Wilkins P, Rivera-Marrero CA, Smith DF, Van Die I, Secor WE, Cummings RD.

Glycobiology. 2014 Jul;24(7):602-18. doi: 10.1093/glycob/cwu029. Epub 2014 Apr 11.


Immunization with recombinantly expressed glycan antigens from Schistosoma mansoni induces glycan-specific antibodies against the parasite.

Prasanphanich NS, Luyai AE, Song X, Heimburg-Molinaro J, Mandalasi M, Mickum M, Smith DF, Nyame AK, Cummings RD.

Glycobiology. 2014 Jul;24(7):619-37. doi: 10.1093/glycob/cwu027. Epub 2014 Apr 11.


Chemistry of natural glycan microarrays.

Song X, Heimburg-Molinaro J, Cummings RD, Smith DF.

Curr Opin Chem Biol. 2014 Feb;18:70-7. doi: 10.1016/j.cbpa.2014.01.001. Epub 2014 Jan 30. Review.


Profiling of glycan receptors for minute virus of mice in permissive cell lines towards understanding the mechanism of cell recognition.

Halder S, Cotmore S, Heimburg-Molinaro J, Smith DF, Cummings RD, Chen X, Trollope AJ, North SJ, Haslam SM, Dell A, Tattersall P, McKenna R, Agbandje-McKenna M.

PLoS One. 2014 Jan 27;9(1):e86909. doi: 10.1371/journal.pone.0086909. eCollection 2014.


Molecular basis of 9G4 B cell autoreactivity in human systemic lupus erythematosus.

Richardson C, Chida AS, Adlowitz D, Silver L, Fox E, Jenks SA, Palmer E, Wang Y, Heimburg-Molinaro J, Li QZ, Mohan C, Cummings R, Tipton C, Sanz I.

J Immunol. 2013 Nov 15;191(10):4926-39. doi: 10.4049/jimmunol.1202263. Epub 2013 Oct 9.


Glycoconjugates in host-helminth interactions.

Prasanphanich NS, Mickum ML, Heimburg-Molinaro J, Cummings RD.

Front Immunol. 2013 Aug 28;4:240. doi: 10.3389/fimmu.2013.00240. eCollection 2013. Review.


Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers.

Ju T, Wang Y, Aryal RP, Lehoux SD, Ding X, Kudelka MR, Cutler C, Zeng J, Wang J, Sun X, Heimburg-Molinaro J, Smith DF, Cummings RD.

Proteomics Clin Appl. 2013 Oct;7(9-10):618-31. doi: 10.1002/prca.201300024. Epub 2013 Sep 9. Review.


Microarray analysis of the human antibody response to synthetic Cryptosporidium glycopeptides.

Heimburg-Molinaro J, Priest JW, Live D, Boons GJ, Song X, Cummings RD, Mead JR.

Int J Parasitol. 2013 Oct;43(11):901-7. doi: 10.1016/j.ijpara.2013.05.012. Epub 2013 Jul 12.


Structure and receptor binding specificity of hemagglutinin H13 from avian influenza A virus H13N6.

Lu X, Qi J, Shi Y, Wang M, Smith DF, Heimburg-Molinaro J, Zhang Y, Paulson JC, Xiao H, Gao GF.

J Virol. 2013 Aug;87(16):9077-85. doi: 10.1128/JVI.00235-13. Epub 2013 Jun 12.


Development and characterization of a specific IgG monoclonal antibody toward the Lewis x antigen using splenocytes of Schistosoma mansoni-infected mice.

Mandalasi M, Dorabawila N, Smith DF, Heimburg-Molinaro J, Cummings RD, Nyame AK.

Glycobiology. 2013 Jul;23(7):877-92. doi: 10.1093/glycob/cwt025. Epub 2013 Mar 29.


Computational screening of the human TF-glycome provides a structural definition for the specificity of anti-tumor antibody JAA-F11.

Tessier MB, Grant OC, Heimburg-Molinaro J, Smith D, Jadey S, Gulick AM, Glushka J, Deutscher SL, Rittenhouse-Olson K, Woods RJ.

PLoS One. 2013;8(1):e54874. doi: 10.1371/journal.pone.0054874. Epub 2013 Jan 24.


Deciphering structural elements of mucin glycoprotein recognition.

Borgert A, Heimburg-Molinaro J, Song X, Lasanajak Y, Ju T, Liu M, Thompson P, Ragupathi G, Barany G, Smith DF, Cummings RD, Live D.

ACS Chem Biol. 2012 Jun 15;7(6):1031-9. doi: 10.1021/cb300076s. Epub 2012 Apr 9.


Lectins identify glycan biomarkers on glioblastoma-derived cancer stem cells.

Tucker-Burden C, Chappa P, Krishnamoorthy M, Gerwe BA, Scharer CD, Heimburg-Molinaro J, Harris W, Usta SN, Eilertson CD, Hadjipanayis CG, Stice SL, Brat DJ, Nash RJ.

Stem Cells Dev. 2012 Sep 1;21(13):2374-86. doi: 10.1089/scd.2011.0369. Epub 2012 Apr 27.


Probing virus-glycan interactions using glycan microarrays.

Heimburg-Molinaro J, Tappert M, Song X, Lasanajak Y, Air G, Smith DF, Cummings RD.

Methods Mol Biol. 2012;808:251-67. doi: 10.1007/978-1-61779-373-8_18.


Glycan microarrays.

Song X, Heimburg-Molinaro J, Smith DF, Cummings RD.

Methods Mol Biol. 2012;800:163-71. doi: 10.1007/978-1-61779-349-3_11.


Cancer vaccines and carbohydrate epitopes.

Heimburg-Molinaro J, Lum M, Vijay G, Jain M, Almogren A, Rittenhouse-Olson K.

Vaccine. 2011 Nov 8;29(48):8802-26. doi: 10.1016/j.vaccine.2011.09.009. Epub 2011 Oct 1. Review.


Analysis of influenza virus hemagglutinin receptor binding mutants with limited receptor recognition properties and conditional replication characteristics.

Bradley KC, Galloway SE, Lasanajak Y, Song X, Heimburg-Molinaro J, Yu H, Chen X, Talekar GR, Smith DF, Cummings RD, Steinhauer DA.

J Virol. 2011 Dec;85(23):12387-98. doi: 10.1128/JVI.05570-11. Epub 2011 Sep 14.


GABRB3 gene expression increases upon ethanol exposure in human embryonic stem cells.

Krishnamoorthy M, Gerwe BA, Scharer CD, Heimburg-Molinaro J, Gregory F, Nash RJ, Arumugham J, Usta SN, Eilertson CD, Stice SL, Nash RJ.

J Recept Signal Transduct Res. 2011 Jun;31(3):206-13. doi: 10.3109/10799893.2011.569723.


Preparation and analysis of glycan microarrays.

Heimburg-Molinaro J, Song X, Smith DF, Cummings RD.

Curr Protoc Protein Sci. 2011 Apr;Chapter 12:Unit12.10. doi: 10.1002/0471140864.ps1210s64.


Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1).

Bradley KC, Jones CA, Tompkins SM, Tripp RA, Russell RJ, Gramer MR, Heimburg-Molinaro J, Smith DF, Cummings RD, Steinhauer DA.

Virology. 2011 May 10;413(2):169-82. doi: 10.1016/j.virol.2011.01.027. Epub 2011 Feb 24.


Shotgun glycomics: a microarray strategy for functional glycomics.

Song X, Lasanajak Y, Xia B, Heimburg-Molinaro J, Rhea JM, Ju H, Zhao C, Molinaro RJ, Cummings RD, Smith DF.

Nat Methods. 2011 Jan;8(1):85-90. doi: 10.1038/nmeth.1540. Epub 2010 Dec 5.


Identification and characterization of endogenous galectins expressed in Madin Darby canine kidney cells.

Poland PA, Rondanino C, Kinlough CL, Heimburg-Molinaro J, Arthur CM, Stowell SR, Smith DF, Hughey RP.

J Biol Chem. 2011 Feb 25;286(8):6780-90. doi: 10.1074/jbc.M110.179002. Epub 2010 Dec 2.


Low ethanol concentration alters CHRNA5 RNA levels during early human development.

Krishnamoorthy M, Gerwe BA, Scharer CD, Heimburg-Molinaro J, Gregory F, Nash RJ, Arumugham J, Stewart B, Stice SL, Nash RJ.

Reprod Toxicol. 2010 Nov;30(3):489-92. doi: 10.1016/j.reprotox.2010.04.011. Epub 2010 May 11.


Innate immune lectins kill bacteria expressing blood group antigen.

Stowell SR, Arthur CM, Dias-Baruffi M, Rodrigues LC, Gourdine JP, Heimburg-Molinaro J, Ju T, Molinaro RJ, Rivera-Marrero C, Xia B, Smith DF, Cummings RD.

Nat Med. 2010 Mar;16(3):295-301. doi: 10.1038/nm.2103. Epub 2010 Feb 14.


Heparin binding epidermal growth factor-like growth factor reduces ethanol-induced apoptosis and differentiation in human embryonic stem cells.

Nash RJ, Heimburg-Molinaro J, Nash RJ.

Growth Factors. 2009 Dec;27(6):362-9. doi: 10.3109/08977190903159953.


Development, characterization, and immunotherapeutic use of peptide mimics of the Thomsen-Friedenreich carbohydrate antigen.

Heimburg-Molinaro J, Almogren A, Morey S, Glinskii OV, Roy R, Wilding GE, Cheng RP, Glinsky VV, Rittenhouse-Olson K.

Neoplasia. 2009 Aug;11(8):780-92.


Development and characterization of antibodies to carbohydrate antigens.

Heimburg-Molinaro J, Rittenhouse-Olson K.

Methods Mol Biol. 2009;534:341-57. doi: 10.1007/978-1-59745-022-5_24. Review.


Heparin binding epidermal growth factor-like growth factor and PD169316 prevent apoptosis in mouse embryonic stem cells.

Krishnamoorthy M, Heimburg-Molinaro J, Bargo AM, Nash RJ, Nash RJ.

J Biochem. 2009 Feb;145(2):177-84. doi: 10.1093/jb/mvn153. Epub 2008 Nov 14.

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