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Items: 1 to 50 of 140

1.

LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function.

Tang F, Gao R, Jeevan-Raj B, Wyss CB, Kalathur RKR, Piscuoglio S, Ng CKY, Hindupur SK, Nuciforo S, Dazert E, Bock T, Song S, Buechel D, Morini MF, Hergovich A, Matthias P, Lim DS, Terracciano LM, Heim MH, Hall MN, Christofori G.

Nat Commun. 2019 Dec 17;10(1):5755. doi: 10.1038/s41467-019-13591-7.

2.

Expression of AXL receptor tyrosine kinase relates to monocyte dysfunction and severity of cirrhosis.

Brenig R, Pop OT, Triantafyllou E, Geng A, Singanayagam A, Perez-Shibayama C, Besse L, Cupovic J, Künzler P, Boldanova T, Brand S, Semela D, Duong FH, Weston CJ, Ludewig B, Heim MH, Wendon J, Antoniades CG, Bernsmeier C.

Life Sci Alliance. 2019 Dec 10;3(1). pii: e201900465. doi: 10.26508/lsa.201900465. Print 2020 Jan.

3.

Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells.

Calabrese D, Roma G, Bergling S, Carbone W, Mele V, Nuciforo S, Fofana I, Campana B, Szkolnicka D, Hay DC, Tchorz J, Bouwmeester T, Wieland S, Heim MH.

PLoS One. 2019 Aug 29;14(8):e0221762. doi: 10.1371/journal.pone.0221762. eCollection 2019.

4.

Unique T-Cell Populations Define Immune-Inflamed Hepatocellular Carcinoma.

Di Blasi D, Boldanova T, Mori L, Terracciano L, Heim MH, De Libero G.

Cell Mol Gastroenterol Hepatol. 2019 Aug 22;9(2):195-218. doi: 10.1016/j.jcmgh.2019.08.004. [Epub ahead of print]

5.

Hepatocellular Carcinoma Xenografts Established From Needle Biopsies Preserve the Characteristics of the Originating Tumors.

Blumer T, Fofana I, Matter MS, Wang X, Montazeri H, Calabrese D, Coto-Llerena M, Boldanova T, Nuciforo S, Kancherla V, Tornillo L, Piscuoglio S, Wieland S, Terracciano LM, Ng CKY, Heim MH.

Hepatol Commun. 2019 May 6;3(7):971-986. doi: 10.1002/hep4.1365. eCollection 2019 Jul.

6.

The IFN-λ Pony Express.

Wieland SF, Heim MH.

Nat Immunol. 2019 May;20(5):522-524. doi: 10.1038/s41590-019-0362-9. No abstract available.

PMID:
30911106
7.

Mapping the Heterogeneity of Histone Modifications on Hepatitis B Virus DNA Using Liver Needle Biopsies Obtained from Chronically Infected Patients.

Flecken T, Meier MA, Skewes-Cox P, Barkan DT, Heim MH, Wieland SF, Holdorf MM.

J Virol. 2019 Apr 17;93(9). pii: e02036-18. doi: 10.1128/JVI.02036-18. Print 2019 May 1.

8.

Growth of Epithelial Organoids in a Defined Hydrogel.

Broguiere N, Isenmann L, Hirt C, Ringel T, Placzek S, Cavalli E, Ringnalda F, Villiger L, Züllig R, Lehmann R, Rogler G, Heim MH, Schüler J, Zenobi-Wong M, Schwank G.

Adv Mater. 2018 Oct;30(43):e1801621. doi: 10.1002/adma.201801621. Epub 2018 Sep 10.

9.

Diagnostic Targeted Sequencing Panel for Hepatocellular Carcinoma Genomic Screening.

Paradiso V, Garofoli A, Tosti N, Lanzafame M, Perrina V, Quagliata L, Matter MS, Wieland S, Heim MH, Piscuoglio S, Ng CKY, Terracciano LM.

J Mol Diagn. 2018 Nov;20(6):836-848. doi: 10.1016/j.jmoldx.2018.07.003. Epub 2018 Aug 22.

10.

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies.

Nuciforo S, Fofana I, Matter MS, Blumer T, Calabrese D, Boldanova T, Piscuoglio S, Wieland S, Ringnalda F, Schwank G, Terracciano LM, Ng CKY, Heim MH.

Cell Rep. 2018 Jul 31;24(5):1363-1376. doi: 10.1016/j.celrep.2018.07.001.

11.

New insights into HDV-induced innate immunity: MDA5 senses HDV replication.

Suslov A, Heim MH, Wieland S.

J Hepatol. 2018 Jul;69(1):5-7. doi: 10.1016/j.jhep.2018.03.030. Epub 2018 Apr 12. No abstract available.

PMID:
29654818
12.

The protein histidine phosphatase LHPP is a tumour suppressor.

Hindupur SK, Colombi M, Fuhs SR, Matter MS, Guri Y, Adam K, Cornu M, Piscuoglio S, Ng CKY, Betz C, Liko D, Quagliata L, Moes S, Jenoe P, Terracciano LM, Heim MH, Hunter T, Hall MN.

Nature. 2018 Mar 29;555(7698):678-682. doi: 10.1038/nature26140. Epub 2018 Mar 21.

13.

Genetic profiling using plasma-derived cell-free DNA in therapy-naïve hepatocellular carcinoma patients: a pilot study.

Ng CKY, Di Costanzo GG, Tosti N, Paradiso V, Coto-Llerena M, Roscigno G, Perrina V, Quintavalle C, Boldanova T, Wieland S, Marino-Marsilia G, Lanzafame M, Quagliata L, Condorelli G, Matter MS, Tortora R, Heim MH, Terracciano LM, Piscuoglio S.

Ann Oncol. 2018 May 1;29(5):1286-1291. doi: 10.1093/annonc/mdy083.

14.

Hepatitis B Virus Does Not Interfere With Innate Immune Responses in the Human Liver.

Suslov A, Boldanova T, Wang X, Wieland S, Heim MH.

Gastroenterology. 2018 May;154(6):1778-1790. doi: 10.1053/j.gastro.2018.01.034. Epub 2018 Mar 19.

15.

[From Molecuar to Natural Medicine].

Allgaier HP, Arnold C, Baumert TF, Becker G, Geißler M, Hafkemeyer P, Harder J, Heim MH, Huber R, Kern WV, Mohr L, Moradpour D, Offensperger S, Offensperger WB, Spangenberg HC, Thimme R, Walter E, von Weizsäcker F.

Dtsch Med Wochenschr. 2018 Jan;143(1):40-45. doi: 10.1055/s-0043-123263. Epub 2018 Jan 9. German. No abstract available.

PMID:
29316584
16.

mTORC2 Promotes Tumorigenesis via Lipid Synthesis.

Guri Y, Colombi M, Dazert E, Hindupur SK, Roszik J, Moes S, Jenoe P, Heim MH, Riezman I, Riezman H, Hall MN.

Cancer Cell. 2017 Dec 11;32(6):807-823.e12. doi: 10.1016/j.ccell.2017.11.011.

17.

In vivo analysis at the cellular level reveals similar steatosis induction in both hepatitis C virus genotype 1 and 3 infections.

Campana B, Calabrese D, Matter MS, Terracciano LM, Wieland SF, Heim MH.

J Viral Hepat. 2018 Mar;25(3):262-271. doi: 10.1111/jvh.12816. Epub 2017 Nov 20.

PMID:
29086446
18.

Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib.

Quintavalle C, Hindupur SK, Quagliata L, Pallante P, Nigro C, Condorelli G, Andersen JB, Tagscherer KE, Roth W, Beguinot F, Heim MH, Ng CKY, Piscuoglio S, Matter MS.

Cell Death Dis. 2017 Oct 26;8(10):e3138. doi: 10.1038/cddis.2017.512.

19.

SOCS1 is an inducible negative regulator of interferon λ (IFN-λ)-induced gene expression in vivo.

Blumer T, Coto-Llerena M, Duong FHT, Heim MH.

J Biol Chem. 2017 Oct 27;292(43):17928-17938. doi: 10.1074/jbc.M117.788877. Epub 2017 Sep 12.

20.

Transcriptional response to hepatitis C virus infection and interferon-alpha treatment in the human liver.

Boldanova T, Suslov A, Heim MH, Necsulea A.

EMBO Mol Med. 2017 Jun;9(6):816-834. doi: 10.15252/emmm.201607006.

21.

A systematic review and meta-analysis of HCV clearance.

Gauthiez E, Habfast-Robertson I, Rüeger S, Kutalik Z, Aubert V, Berg T, Cerny A, Gorgievski M, George J, Heim MH, Malinverni R, Moradpour D, Müllhaupt B, Negro F, Semela D, Semmo N, Villard J, Bibert S, Bochud PY; Swiss Hepatitis C Cohort Study.

Liver Int. 2017 Oct;37(10):1431-1445. doi: 10.1111/liv.13401. Epub 2017 Mar 30. Review.

PMID:
28261910
22.

Hepatitis B virus covalently closed circular DNA homeostasis is independent of the lymphotoxin pathway during chronic HBV infection.

Meier MA, Suslov A, Ketterer S, Heim MH, Wieland SF.

J Viral Hepat. 2017 Aug;24(8):662-671. doi: 10.1111/jvh.12689. Epub 2017 Mar 13.

PMID:
28182305
23.

miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis.

Van Renne N, Roca Suarez AA, Duong FHT, Gondeau C, Calabrese D, Fontaine N, Ababsa A, Bandiera S, Croonenborghs T, Pochet N, De Blasi V, Pessaux P, Piardi T, Sommacale D, Ono A, Chayama K, Fujita M, Nakagawa H, Hoshida Y, Zeisel MB, Heim MH, Baumert TF, Lupberger J.

Gut. 2018 May;67(5):953-962. doi: 10.1136/gutjnl-2016-312270. Epub 2017 Feb 3.

24.

Liver damage and senescence increases in patients developing hepatocellular carcinoma.

Rey S, Quintavalle C, Burmeister K, Calabrese D, Schlageter M, Quagliata L, Cathomas G, Diebold J, Molinolo A, Heim MH, Terracciano LM, Matter MS.

J Gastroenterol Hepatol. 2017 Aug;32(8):1480-1486. doi: 10.1111/jgh.13717.

PMID:
28052383
25.

HMGA1 Expression in Human Hepatocellular Carcinoma Correlates with Poor Prognosis and Promotes Tumor Growth and Migration in in vitro Models.

Andreozzi M, Quintavalle C, Benz D, Quagliata L, Matter M, Calabrese D, Tosti N, Ruiz C, Trapani F, Tornillo L, Fusco A, Heim MH, Ng CK, Pallante P, Terracciano LM, Piscuoglio S.

Neoplasia. 2016 Dec;18(12):724-731. doi: 10.1016/j.neo.2016.10.002. Epub 2016 Nov 14.

26.

Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS.

Nat Cell Biol. 2016 Oct 27;18(11):1260. doi: 10.1038/ncb3428. No abstract available.

PMID:
27784900
27.

A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients.

Ulveling D, Le Clerc S, Cobat A, Labib T, Noirel J, Laville V, Coulonges C, Carpentier W, Nalpas B, Heim MH, Poynard T, Cerny A, Pol S, Bochud PY, Dabis F, Theodorou I, Lévy Y, Salmon D, Abel L, Dominguez S, Zagury JF; HEPAVIH ANRS CO13 Cohort Study Group; Swiss Hepatitis C Cohort Study Group; French ANRS HC EP 26 Genoscan Study Group.

Hepatology. 2016 Nov;64(5):1462-1472. doi: 10.1002/hep.28695. Epub 2016 Jul 29.

PMID:
27339598
28.

Hepatic Deletion of Janus Kinase 2 Counteracts Oxidative Stress in Mice.

Themanns M, Mueller KM, Kessler SM, Golob-Schwarzl N, Mohr T, Kaltenecker D, Bourgeais J, Paier-Pourani J, Friedbichler K, Schneller D, Schlederer M, Zebedin-Brandl E, Terracciano LM, Han X, Kenner L, Wagner KU, Mikulits W, Kozlov AV, Heim MH, Gouilleux F, Haybaeck J, Moriggl R.

Sci Rep. 2016 Oct 7;6:34719. doi: 10.1038/srep34719.

29.

The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation.

Mobin MB, Gerstberger S, Teupser D, Campana B, Charisse K, Heim MH, Manoharan M, Tuschl T, Stoffel M.

Nat Commun. 2016 Sep 26;7:12848. doi: 10.1038/ncomms12848.

30.

Host - hepatitis C viral interactions: The role of genetics.

Heim MH, Bochud PY, George J.

J Hepatol. 2016 Oct;65(1 Suppl):S22-S32. doi: 10.1016/j.jhep.2016.07.037. Review.

PMID:
27641986
31.

Gene expression analysis of biopsy samples reveals critical limitations of transcriptome-based molecular classifications of hepatocellular carcinoma.

Makowska Z, Boldanova T, Adametz D, Quagliata L, Vogt JE, Dill MT, Matter MS, Roth V, Terracciano L, Heim MH.

J Pathol Clin Res. 2016 Feb 5;2(2):80-92. doi: 10.1002/cjp2.37. eCollection 2016 Apr.

32.

Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation.

Bernsmeier C, Dill MT, Provenzano A, Makowska Z, Krol I, Muscogiuri G, Semela D, Tornillo L, Marra F, Heim MH, Duong FH.

Lab Invest. 2016 Sep;96(9):972-80. doi: 10.1038/labinvest.2016.75. Epub 2016 Jul 18.

33.

Hepatitis C Virus-Induced Upregulation of MicroRNA miR-146a-5p in Hepatocytes Promotes Viral Infection and Deregulates Metabolic Pathways Associated with Liver Disease Pathogenesis.

Bandiera S, Pernot S, El Saghire H, Durand SC, Thumann C, Crouchet E, Ye T, Fofana I, Oudot MA, Barths J, Schuster C, Pessaux P, Heim MH, Baumert TF, Zeisel MB.

J Virol. 2016 Jun 24;90(14):6387-6400. doi: 10.1128/JVI.00619-16. Print 2016 Jul 15.

34.

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS.

Nat Cell Biol. 2016 May;18(5):467-79. doi: 10.1038/ncb3337. Epub 2016 Apr 18. Erratum in: Nat Cell Biol. 2016 Oct 27;18(11):1260.

PMID:
27088858
35.

Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient.

Dazert E, Colombi M, Boldanova T, Moes S, Adametz D, Quagliata L, Roth V, Terracciano L, Heim MH, Jenoe P, Hall MN.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1381-6. doi: 10.1073/pnas.1523434113. Epub 2016 Jan 19.

36.

Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls.

Bernsmeier C, Weisskopf DM, Pflueger MO, Mosimann J, Campana B, Terracciano L, Beglinger C, Heim MH, Cajochen C.

PLoS One. 2015 Nov 17;10(11):e0143293. doi: 10.1371/journal.pone.0143293. eCollection 2015.

37.

YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors.

Marti P, Stein C, Blumer T, Abraham Y, Dill MT, Pikiolek M, Orsini V, Jurisic G, Megel P, Makowska Z, Agarinis C, Tornillo L, Bouwmeester T, Ruffner H, Bauer A, Parker CN, Schmelzle T, Terracciano LM, Heim MH, Tchorz JS.

Hepatology. 2015 Nov;62(5):1497-510. doi: 10.1002/hep.27992. Epub 2015 Aug 25.

PMID:
26173433
38.

Corrigendum: reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes.

Terczyńska-Dyla E, Bibert S, Duong FHT, Krol I, Jørgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, Müllhaupt B, Negro F, Santoro R, Semela D, Semmo N; Swiss Hepatitis C Cohort Study Group, Heim MH, Bochud PY, Hartmann R.

Nat Commun. 2015 Jun 29;6:7280. doi: 10.1038/ncomms8280. No abstract available.

39.

Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation.

Anggakusuma, Romero-Brey I, Berger C, Colpitts CC, Boldanova T, Engelmann M, Todt D, Perin PM, Behrendt P, Vondran FW, Xu S, Goffinet C, Schang LM, Heim MH, Bartenschlager R, Pietschmann T, Steinmann E.

Hepatology. 2015 Sep;62(3):702-14. doi: 10.1002/hep.27913. Epub 2015 Jul 28.

PMID:
25999047
40.

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody.

Mailly L, Xiao F, Lupberger J, Wilson GK, Aubert P, Duong FHT, Calabrese D, Leboeuf C, Fofana I, Thumann C, Bandiera S, Lütgehetmann M, Volz T, Davis C, Harris HJ, Mee CJ, Girardi E, Chane-Woon-Ming B, Ericsson M, Fletcher N, Bartenschlager R, Pessaux P, Vercauteren K, Meuleman P, Villa P, Kaderali L, Pfeffer S, Heim MH, Neunlist M, Zeisel MB, Dandri M, McKeating JA, Robinet E, Baumert TF.

Nat Biotechnol. 2015 May;33(5):549-554. doi: 10.1038/nbt.3179. Epub 2015 Mar 23.

41.

Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes.

Terczyńska-Dyla E, Bibert S, Duong FH, Krol I, Jørgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, Müllhaupt B, Negro F, Santoro R, Semela D, Semmo N; Swiss Hepatitis C Cohort Study Group, Heim MH, Bochud PY, Hartmann R.

Nat Commun. 2014 Dec 23;5:5699. doi: 10.1038/ncomms6699. Erratum in: Nat Commun. 2015;6:7280.

PMID:
25534433
42.

An intrahepatic transcriptional signature of enhanced immune activity predicts response to peginterferon in chronic hepatitis B.

Jansen L, de Niet A, Makowska Z, Dill MT, van Dort KA, Terpstra V, Bart Takkenberg R, Janssen HL, Heim MH, Kootstra NA, Reesink HW.

Liver Int. 2015 Jul;35(7):1824-32. doi: 10.1111/liv.12768. Epub 2015 Jan 21.

PMID:
25533046
43.

Innate and adaptive immune responses in HCV infections.

Heim MH, Thimme R.

J Hepatol. 2014 Nov;61(1 Suppl):S14-25. doi: 10.1016/j.jhep.2014.06.035. Epub 2014 Nov 3. Review.

44.

Generation of a murine hepatic angiosarcoma cell line and reproducible mouse tumor model.

Rothweiler S, Dill MT, Terracciano L, Makowska Z, Quagliata L, Hlushchuk R, Djonov V, Heim MH, Semela D.

Lab Invest. 2015 Mar;95(3):351-62. doi: 10.1038/labinvest.2014.141. Epub 2014 Nov 24.

45.

Impact of common risk factors of fibrosis progression in chronic hepatitis C.

Rüeger S, Bochud PY, Dufour JF, Müllhaupt B, Semela D, Heim MH, Moradpour D, Cerny A, Malinverni R, Booth DR, Suppiah V, George J, Argiro L, Halfon P, Bourlière M, Talal AH, Jacobson IM, Patin E, Nalpas B, Poynard T, Pol S, Abel L, Kutalik Z, Negro F.

Gut. 2015 Oct;64(10):1605-15. doi: 10.1136/gutjnl-2014-306997. Epub 2014 Sep 11.

PMID:
25214320
46.

Clinical course of infection and viral tissue tropism of hepatitis C virus-like nonprimate hepaciviruses in horses.

Pfaender S, Cavalleri JM, Walter S, Doerrbecker J, Campana B, Brown RJ, Burbelo PD, Postel A, Hahn K, Anggakusuma, Riebesehl N, Baumgärtner W, Becher P, Heim MH, Pietschmann T, Feige K, Steinmann E.

Hepatology. 2015 Feb;61(2):447-59. doi: 10.1002/hep.27440. Epub 2015 Jan 5.

PMID:
25212983
47.

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index.

Hoggart CJ, Venturini G, Mangino M, Gomez F, Ascari G, Zhao JH, Teumer A, Winkler TW, Tšernikova N, Luan J, Mihailov E, Ehret GB, Zhang W, Lamparter D, Esko T, Macé A, Rüeger S, Bochud PY, Barcella M, Dauvilliers Y, Benyamin B, Evans DM, Hayward C, Lopez MF, Franke L, Russo A, Heid IM, Salvi E, Vendantam S, Arking DE, Boerwinkle E, Chambers JC, Fiorito G, Grallert H, Guarrera S, Homuth G, Huffman JE, Porteous D; Generation Scotland Consortium; LifeLines Cohort study; GIANT Consortium, Moradpour D, Iranzo A, Hebebrand J, Kemp JP, Lammers GJ, Aubert V, Heim MH, Martin NG, Montgomery GW, Peraita-Adrados R, Santamaria J, Negro F, Schmidt CO, Scott RA, Spector TD, Strauch K, Völzke H, Wareham NJ, Yuan W, Bell JT, Chakravarti A, Kooner JS, Peters A, Matullo G, Wallaschofski H, Whitfield JB, Paccaud F, Vollenweider P, Bergmann S, Beckmann JS, Tafti M, Hastie ND, Cusi D, Bochud M, Frayling TM, Metspalu A, Jarvelin MR, Scherag A, Smith GD, Borecki IB, Rousson V, Hirschhorn JN, Rivolta C, Loos RJ, Kutalik Z.

PLoS Genet. 2014 Jul 31;10(7):e1004508. doi: 10.1371/journal.pgen.1004508. eCollection 2014 Jul.

48.

The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota.

Balmer ML, Slack E, de Gottardi A, Lawson MA, Hapfelmeier S, Miele L, Grieco A, Van Vlierberghe H, Fahrner R, Patuto N, Bernsmeier C, Ronchi F, Wyss M, Stroka D, Dickgreber N, Heim MH, McCoy KD, Macpherson AJ.

Sci Transl Med. 2014 May 21;6(237):237ra66. doi: 10.1126/scitranslmed.3008618.

49.

Vitamin D receptor and Jak-STAT signaling crosstalk results in calcitriol-mediated increase of hepatocellular response to IFN-α.

Lange CM, Gouttenoire J, Duong FH, Morikawa K, Heim MH, Moradpour D.

J Immunol. 2014 Jun 15;192(12):6037-44. doi: 10.4049/jimmunol.1302296. Epub 2014 May 12.

50.

IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies.

Duong FH, Trincucci G, Boldanova T, Calabrese D, Campana B, Krol I, Durand SC, Heydmann L, Zeisel MB, Baumert TF, Heim MH.

J Exp Med. 2014 May 5;211(5):857-68. doi: 10.1084/jem.20131557. Epub 2014 Apr 21.

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