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Items: 1 to 50 of 202

1.

Virtual monochromatic spectral imaging versus linearly blended dual-energy and single-energy imaging during CT-guided biopsy needle positioning: Optimization of keV settings and impact on image quality.

Do TD, Heim J, Melzig C, Vollherbst DF, Kauczor HU, Skornitzke S, Sommer CM.

PLoS One. 2020 Feb 10;15(2):e0228578. doi: 10.1371/journal.pone.0228578. eCollection 2020.

2.

Biallelic mutations of TBC1D24 in exercise-induced paroxysmal dystonia.

Steel D, Heim J, Kruer MC, Sanchis-Juan A, Raymond LF, Eunson P, Kurian MA.

Mov Disord. 2020 Feb;35(2):372-373. doi: 10.1002/mds.27981. Epub 2020 Jan 10. No abstract available.

PMID:
31922275
3.

Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site.

Heim JB, Hodnik V, Heggelund JE, Anderluh G, Krengel U.

Sci Rep. 2019 Aug 22;9(1):12243. doi: 10.1038/s41598-019-48579-2.

4.

Upper limits on perturbations of nuclear decay rates induced by reactor electron antineutrinos.

Barnes VE, Bernstein DJ, Bryan CD, Cinko N, Deichert GG, Gruenwald JT, Heim JM, Kaplan HB, LaZur R, Neff D, Nistor JM, Sahelijo N, Fischbach E.

Appl Radiat Isot. 2019 Jul;149:182-199. doi: 10.1016/j.apradiso.2019.01.027. Epub 2019 Feb 13.

PMID:
31075563
5.

Specificity of Escherichia coli Heat-Labile Enterotoxin Investigated by Single-Site Mutagenesis and Crystallography.

Heggelund JE, Heim JB, Bajc G, Hodnik V, Anderluh G, Krengel U.

Int J Mol Sci. 2019 Feb 6;20(3). pii: E703. doi: 10.3390/ijms20030703.

6.

Non-human Papillomavirus Cervical Mucinous Adenocarcinoma in a Phenotypic Male with Congenital Adrenal Hyperplasia.

Heim J, Dickson E, Geller MA, Rivard C.

Cureus. 2018 Nov 18;10(11):e3607. doi: 10.7759/cureus.3607.

7.

Genomic Analyses of Acute Flaccid Myelitis Cases among a Cluster in Arizona Provide Further Evidence of Enterovirus D68 Role.

Bowers JR, Valentine M, Harrison V, Fofanov VY, Gillece J, Delisle J, Patton B, Schupp J, Sheridan K, Lemmer D, Ostdiek S, Bains HK, Heim J, Sylvester T, Prasai S, Kretschmer M, Fowle N, Komatsu K, Brady S, Robinson S, Fitzpatrick K, Ostovar GA, Alsop E, Hutchins E, Jensen K, Keim P, Engelthaler DM.

mBio. 2019 Jan 22;10(1). pii: e02262-18. doi: 10.1128/mBio.02262-18.

8.

Predicting the Future: Using Simulation Modeling to Forecast Patient Flow on General Medicine Units.

Mishra V, Tu SP, Heim J, Masters H, Hall L, Clark RR, Dow AW.

J Hosp Med. 2019 Jan 8;14(1):9-15. doi: 10.12788/jhm.3081. Epub 2018 Nov 28.

PMID:
30534642
9.

Salivary beta amyloid protein levels are detectable and differentiate patients with Alzheimer's disease dementia from normal controls: preliminary findings.

Sabbagh MN, Shi J, Lee M, Arnold L, Al-Hasan Y, Heim J, McGeer P.

BMC Neurol. 2018 Sep 26;18(1):155. doi: 10.1186/s12883-018-1160-y.

10.

FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis.

Heim JB, McDonald CA, Wyles SP, Sominidi-Damodaran S, Squirewell EJ, Li M, Motsonelidze C, Böttcher RT, van Deursen J, Meves A.

PLoS One. 2018 Jul 12;13(7):e0200558. doi: 10.1371/journal.pone.0200558. eCollection 2018.

11.

Environmental risk assessment of biocidal products: identification of relevant components and reliability of a component-based mixture assessment.

Coors A, Vollmar P, Heim J, Sacher F, Kehrer A.

Environ Sci Eur. 2018;30(1):3. doi: 10.1186/s12302-017-0130-0. Epub 2018 Jan 18.

12.

Are there fitness costs of adaptive pyrethroid resistance in the amphipod, Hyalella azteca?

Heim JR, Weston DP, Major K, Poynton H, Huff Hartz KE, Lydy MJ.

Environ Pollut. 2018 Apr;235:39-46. doi: 10.1016/j.envpol.2017.12.043. Epub 2017 Dec 20.

PMID:
29274536
13.

Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.

Burschowsky D, Thorbjørnsrud HV, Heim JB, Fahrig-Kamarauskaitė JR, Würth-Roderer K, Kast P, Krengel U.

Biochemistry. 2018 Feb 6;57(5):557-573. doi: 10.1021/acs.biochem.7b01018. Epub 2017 Dec 21.

PMID:
29178787
14.

Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines.

Alirol E, Wi TE, Bala M, Bazzo ML, Chen XS, Deal C, Dillon JR, Kularatne R, Heim J, Hooft van Huijsduijnen R, Hook EW, Lahra MM, Lewis DA, Ndowa F, Shafer WM, Tayler L, Workowski K, Unemo M, Balasegaram M.

PLoS Med. 2017 Jul 26;14(7):e1002366. doi: 10.1371/journal.pmed.1002366. eCollection 2017 Jul.

15.

Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics.

Heggelund JE, Mackenzie A, Martinsen T, Heim JB, Cheshev P, Bernardi A, Krengel U.

Sci Rep. 2017 May 24;7(1):2326. doi: 10.1038/s41598-017-02179-0.

16.

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.

Heim JB, Squirewell EJ, Neu A, Zocher G, Sominidi-Damodaran S, Wyles SP, Nikolova E, Behrendt N, Saunte DM, Lock-Andersen J, Gaonkar KS, Yan H, Sarkaria JN, Krendel M, van Deursen J, Sprangers R, Stehle T, Böttcher RT, Lee JH, Ordog T, Meves A.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3933-3938. doi: 10.1073/pnas.1614894114. Epub 2017 Mar 27.

17.

EFFECTS OF MOUTHING AND INTERLOCUTOR PRESENCE ON MOVEMENTS OF VISIBLE VS. NON-VISIBLE ARTICULATORS.

Bicevskis K, de Vries J, Green L, Heim J, Božič J, D'Aquisto J, Fry M, Sadlier-Brown E, Tkachman O, Yamane N, Gick B.

Can Acoust. 2016;44(1):17-24.

18.

Evaluation of the American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator in Gynecologic Oncology Patients Undergoing Minimally Invasive Surgery.

Teoh D, Halloway RN, Heim J, Vogel RI, Rivard C.

J Minim Invasive Gynecol. 2017 Jan 1;24(1):48-54. doi: 10.1016/j.jmig.2016.10.005. Epub 2016 Oct 24.

19.

Do pyrethroid-resistant Hyalella azteca have greater bioaccumulation potential compared to non-resistant populations? Implications for bioaccumulation in fish.

Muggelberg LL, Huff Hartz KE, Nutile SA, Harwood AD, Heim JR, Derby AP, Weston DP, Lydy MJ.

Environ Pollut. 2017 Jan;220(Pt A):375-382. doi: 10.1016/j.envpol.2016.09.073. Epub 2016 Oct 15.

PMID:
27756597
20.

RNA-seq Identification of RACGAP1 as a Metastatic Driver in Uterine Carcinosarcoma.

Mi S, Lin M, Brouwer-Visser J, Heim J, Smotkin D, Hebert T, Gunter MJ, Goldberg GL, Zheng D, Huang GS.

Clin Cancer Res. 2016 Sep 15;22(18):4676-86. doi: 10.1158/1078-0432.CCR-15-2116. Epub 2016 Apr 27.

21.

Investigation of Acidithiobacillus ferrooxidans in pure and mixed-species culture for bioleaching of Theisen sludge from former copper smelting.

Klink C, Eisen S, Daus B, Heim J, Schlömann M, Schopf S.

J Appl Microbiol. 2016 Jun;120(6):1520-30. doi: 10.1111/jam.13142. Epub 2016 Apr 25.

22.

Tumor Cell Adhesion As a Risk Factor for Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma.

Meves A, Nikolova E, Heim JB, Squirewell EJ, Cappel MA, Pittelkow MR, Otley CC, Behrendt N, Saunte DM, Lock-Andersen J, Schenck LA, Weaver AL, Suman VJ.

J Clin Oncol. 2015 Aug 10;33(23):2509-15. doi: 10.1200/JCO.2014.60.7002. Epub 2015 Jul 6.

23.

Design and implementation of a combined influenza immunization and tuberculosis screening campaign with simulation modelling.

Heim JA, Huang H, Zabinsky ZB, Dickerson J, Wellner M, Astion M, Cruz D, Vincent J, Jack R.

J Eval Clin Pract. 2015 Aug;21(4):727-34. doi: 10.1111/jep.12377. Epub 2015 May 26.

PMID:
26009843
24.

Genotoxic effects of zinc oxide nanoparticles.

Heim J, Felder E, Tahir MN, Kaltbeitzel A, Heinrich UR, Brochhausen C, Mailänder V, Tremel W, Brieger J.

Nanoscale. 2015 May 21;7(19):8931-8. doi: 10.1039/c5nr01167a.

PMID:
25916659
25.

Proteomic identification of the heterogeneous nuclear ribonucleoprotein K as irradiation responsive protein related to migration.

Strozynski J, Heim J, Bunbanjerdsuk S, Wiesmann N, Zografidou L, Becker SK, Meierl AM, Gouveris H, Lüddens H, Grus F, Brieger J.

J Proteomics. 2015 Jan 15;113:154-61. doi: 10.1016/j.jprot.2014.09.017. Epub 2014 Oct 2.

PMID:
25281771
26.

Neither snow nor rain: contingency planning by a clinical reference laboratory courier service for weather related emergencies.

Bankson DD, Heim JA.

Lab Med. 2014 Summer;45(3):e128-38. doi: 10.1309/LMX71RQD0KNIDIEB.

PMID:
25217517
27.

IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells.

Tamzalit F, Barbieux I, Plet A, Heim J, Nedellec S, Morisseau S, Jacques Y, Mortier E.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8565-70. doi: 10.1073/pnas.1405514111. Epub 2014 May 27.

28.

Incidence of type 2 diabetes among patients exposed to the combination of pravastatin and paroxetine.

Gooden KM, Bibeau KB, Wood J, Irizarry MC, Pan X, Allen J, Sampson T, Heim JM.

Curr Drug Saf. 2015;10(2):152-8.

PMID:
24861991
29.

Yeast synthetic biology platform generates novel chemical structures as scaffolds for drug discovery.

Klein J, Heal JR, Hamilton WD, Boussemghoune T, Tange TØ, Delegrange F, Jaeschke G, Hatsch A, Heim J.

ACS Synth Biol. 2014 May 16;3(5):314-23. doi: 10.1021/sb400177x. Epub 2014 Jan 30.

30.

Vinylogous chain branching catalysed by a dedicated polyketide synthase module.

Bretschneider T, Heim JB, Heine D, Winkler R, Busch B, Kusebauch B, Stehle T, Zocher G, Hertweck C.

Nature. 2013 Oct 3;502(7469):124-8. doi: 10.1038/nature12588. Epub 2013 Sep 18.

PMID:
24048471
31.

Use of an algorithm for identifying hidden drug–drug interactions in adverse event reports.

Gooden KM, Pan X, Kawabata H, Heim JM.

J Am Med Inform Assoc. 2013 May;20(3):590. No abstract available.

32.

Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase.

Zocher G, Saleh O, Heim JB, Herbst DA, Heide L, Stehle T.

PLoS One. 2012;7(10):e48427. doi: 10.1371/journal.pone.0048427. Epub 2012 Oct 31.

33.

The alpha subunit of the G protein G13 regulates activity of one or more Gli transcription factors independently of smoothened.

Douglas AE, Heim JA, Shen F, Almada LL, Riobo NA, Fernández-Zapico ME, Manning DR.

J Biol Chem. 2011 Sep 2;286(35):30714-22. doi: 10.1074/jbc.M111.219279. Epub 2011 Jul 11.

34.

Tapping the potential of intact cell mass spectrometry with a combined data analytical approach applied to Yersinia spp.: detection, differentiation and identification of Y. pestis.

Wittwer M, Heim J, Schär M, Dewarrat G, Schürch N.

Syst Appl Microbiol. 2011 Feb;34(1):12-9. doi: 10.1016/j.syapm.2010.11.006. Epub 2011 Jan 15.

PMID:
21239132
35.

A multifactorial approach to understanding fall risk in older people.

Delbaere K, Close JC, Heim J, Sachdev PS, Brodaty H, Slavin MJ, Kochan NA, Lord SR.

J Am Geriatr Soc. 2010 Sep;58(9):1679-85. doi: 10.1111/j.1532-5415.2010.03017.x.

PMID:
20863327
36.

DISCO: distance and spectrum correlation optimization alignment for two-dimensional gas chromatography time-of-flight mass spectrometry-based metabolomics.

Wang B, Fang A, Heim J, Bogdanov B, Pugh S, Libardoni M, Zhang X.

Anal Chem. 2010 Jun 15;82(12):5069-81. doi: 10.1021/ac100064b.

37.

Investigation of the exclusive 3He(e,e' pn)1H reaction.

Middleton DG, Annand JR, Antelo MA, Ayerbe C, Barneo P, Baumann D, Bermuth J, Bernauer J, Blok HP, Böhm R, Bosnar D, Ding M, Distler MO, Friedrich J, Llongo JG, Glazier DI, Golak J, Glöckle W, Grabmayr P, Hehl T, Heim J, Hesselink WH, Jans E, Kamada H, Mañas GJ, Kohl M, Lapikás L, MacGregor IJ, Martin I, McGeorge JC, Merkel H, Merle P, Monstad K, Moschini F, Müller U, Nogga A, Pérez-Benito R, Pospischil T, Potokar M, Rosner G, Seimetz M, Skibiński R, de Vries H, Walcher T, Watts DP, Weinriefer M, Weiss M, Witała H, Zihlmann B.

Phys Rev Lett. 2009 Oct 9;103(15):152501. Epub 2009 Oct 7.

PMID:
19905628
38.

Prospects for the next anti-Pseudomonas drug.

Page MG, Heim J.

Curr Opin Pharmacol. 2009 Oct;9(5):558-65. doi: 10.1016/j.coph.2009.08.006. Epub 2009 Sep 12. Review.

PMID:
19748829
39.

New molecules from old classes: revisiting the development of beta-lactams.

Page MG, Heim J.

IDrugs. 2009 Sep;12(9):561-5.

PMID:
19697275
40.

Identification of Taenia sp. in a mummy from a Christian Necropolis in El-Deir, Oasis of Kharga, ancient Egypt.

Le Bailly M, Mouze S, da Rocha GC, Heim JL, Lichtenberg R, Dunand F, Bouchet F.

J Parasitol. 2010 Feb;96(1):213-5. doi: 10.1645/GE-2076.1.

PMID:
19681649
41.

In vitro and in vivo properties of dihydrophthalazine antifolates, a novel family of antibacterial drugs.

Caspers P, Bury L, Gaucher B, Heim J, Shapiro S, Siegrist S, Schmitt-Hoffmann A, Thenoz L, Urwyler H.

Antimicrob Agents Chemother. 2009 Sep;53(9):3620-7. doi: 10.1128/AAC.00377-09. Epub 2009 Jun 22.

42.

Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta.

Reynaert NL, van der Vliet A, Guala AS, McGovern T, Hristova M, Pantano C, Heintz NH, Heim J, Ho YS, Matthews DE, Wouters EF, Janssen-Heininger YM.

Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13086-91. Epub 2006 Aug 17.

43.

New cytochrome P450 2D6*56 allele identified by genotype/phenotype analysis of cryopreserved human hepatocytes.

Li L, Pan RM, Porter TD, Jensen NS, Silber P, Russo G, Tine JA, Heim J, Ring B, Wedlund PJ.

Drug Metab Dispos. 2006 Aug;34(8):1411-6. Epub 2006 May 5.

PMID:
16679388
44.

Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.

Rehmel JL, Eckstein JA, Farid NA, Heim JB, Kasper SC, Kurihara A, Wrighton SA, Ring BJ.

Drug Metab Dispos. 2006 Apr;34(4):600-7. Epub 2006 Jan 13.

PMID:
16415119
45.

Hematopoietic transcription factor GATA-2 promotes upregulation of alpha globin and cell death in FL5.12 cells.

Brecht K, Simonen M, Kamke M, Heim J.

Apoptosis. 2005 Oct;10(5):1063-78.

PMID:
16151640
46.

Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12.

Brecht K, Simonen M, Heim J.

Apoptosis. 2005 Oct;10(5):1043-62.

PMID:
16151639
47.

Suspected central anticholinergic syndrome in a 6-week-old infant.

Kulka PJ, Toker H, Heim J, Joist A, Jakschik J.

Anesth Analg. 2004 Nov;99(5):1376-8; table of contents.

PMID:
15502033
48.

Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium.

Palmer BM, Noguchi T, Wang Y, Heim JR, Alpert NR, Burgon PG, Seidman CE, Seidman JG, Maughan DW, LeWinter MM.

Circ Res. 2004 Jun 25;94(12):1615-22. Epub 2004 May 20.

PMID:
15155526
49.

Oxidative stress and hemorheological changes induced by acute treadmill exercise.

Ajmani RS, Fleg JL, Demehin AA, Wright JG, O'Connor F, Heim JM, Tarien E, Rifkind JM.

Clin Hemorheol Microcirc. 2003;28(1):29-40.

PMID:
12632010
50.

Second-site NMR screening and linker design.

Jahnke W, Flörsheimer A, Blommers MJ, Paris CG, Heim J, Nalin CM, Perez LB.

Curr Top Med Chem. 2003;3(1):69-80. Review.

PMID:
12570778

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