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Items: 37

1.

Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases.

Holzer T, Probst K, Etich J, Auler M, Georgieva VS, Bluhm B, Frie C, Heilig J, Niehoff A, Nüchel J, Plomann M, Seeger JM, Kashkar H, Baris OR, Wiesner RJ, Brachvogel B.

J Cell Biol. 2019 May 13. pii: jcb.201809056. doi: 10.1083/jcb.201809056. [Epub ahead of print]

PMID:
31085560
2.

Plastin 3 influences bone homeostasis through regulation of osteoclast activity.

Neugebauer J, Heilig J, Hosseinibarkooie S, Ross BC, Mendoza-Ferreira N, Nolte F, Peters M, Hölker I, Hupperich K, Tschanz T, Grysko V, Zaucke F, Niehoff A, Wirth B.

Hum Mol Genet. 2018 Dec 15;27(24):4249-4262. doi: 10.1093/hmg/ddy318.

PMID:
30204862
3.

Impact of Arginine to Cysteine Mutations in Collagen II on Protein Secretion and Cell Survival.

Chakkalakal SA, Heilig J, Baumann U, Paulsson M, Zaucke F.

Int J Mol Sci. 2018 Feb 11;19(2). pii: E541. doi: 10.3390/ijms19020541.

4.

miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage.

Bluhm B, Ehlen HWA, Holzer T, Georgieva VS, Heilig J, Pitzler L, Etich J, Bortecen T, Frie C, Probst K, Niehoff A, Belluoccio D, Van den Bergen J, Brachvogel B.

Development. 2017 Oct 1;144(19):3562-3577. doi: 10.1242/dev.148429. Epub 2017 Aug 29.

5.

Extracellular Distribution of Collagen II and Perifibrillar Adapter Proteins in Healthy and Osteoarthritic Human Knee Joint Cartilage.

Firner S, Zaucke F, Michael J, Dargel J, Schiwy-Bochat KH, Heilig J, Rothschild MA, Eysel P, Brüggemann GP, Niehoff A.

J Histochem Cytochem. 2017 Oct;65(10):593-606. doi: 10.1369/0022155417729154. Epub 2017 Aug 28.

6.

Neutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition.

Stoffel W, Hammels I, Jenke B, Binczek E, Schmidt-Soltau I, Brodesser S, Schauss A, Etich J, Heilig J, Zaucke F.

Cell Death Dis. 2016 Nov 24;7(11):e2488. doi: 10.1038/cddis.2016.385.

7.

Immunogenicity associated with metreleptin treatment in patients with obesity or lipodystrophy.

Chan JL, Koda J, Heilig JS, Cochran EK, Gorden P, Oral EA, Brown RJ.

Clin Endocrinol (Oxf). 2016 Jul;85(1):137-49. doi: 10.1111/cen.12980. Epub 2016 Feb 2.

8.

Insulin-like growth factor 1 receptor (IGF1R) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification.

Heilig J, Paulsson M, Zaucke F.

Bone. 2016 Feb;83:48-57. doi: 10.1016/j.bone.2015.10.007. Epub 2015 Oct 22. No abstract available.

PMID:
26475121
9.

Collagen II regulates chondroycte integrin expression profile and differentiation.

Xin W, Heilig J, Paulsson M, Zaucke F.

Connect Tissue Res. 2015;56(4):307-14. doi: 10.3109/03008207.2015.1026965. Epub 2015 Apr 29.

PMID:
25803621
10.

Moderate cyclic tensile strain alters the assembly of cartilage extracellular matrix proteins in vitro.

Bleuel J, Zaucke F, Brüggemann GP, Heilig J, Wolter ML, Hamann N, Firner S, Niehoff A.

J Biomech Eng. 2015 Jun;137(6):061009. doi: 10.1115/1.4030053. Epub 2015 Apr 14.

PMID:
25782164
11.

Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment.

Clapper JR, Hendricks MD, Gu G, Wittmer C, Dolman CS, Herich J, Athanacio J, Villescaz C, Ghosh SS, Heilig JS, Lowe C, Roth JD.

Am J Physiol Gastrointest Liver Physiol. 2013 Oct 1;305(7):G483-95. doi: 10.1152/ajpgi.00079.2013. Epub 2013 Jul 25.

12.

First result from the Alpha Magnetic Spectrometer on the International Space Station: precision measurement of the positron fraction in primary cosmic rays of 0.5-350 GeV.

Aguilar M, Alberti G, Alpat B, Alvino A, Ambrosi G, Andeen K, Anderhub H, Arruda L, Azzarello P, Bachlechner A, Barao F, Baret B, Barrau A, Barrin L, Bartoloni A, Basara L, Basili A, Batalha L, Bates J, Battiston R, Bazo J, Becker R, Becker U, Behlmann M, Beischer B, Berdugo J, Berges P, Bertucci B, Bigongiari G, Biland A, Bindi V, Bizzaglia S, Boella G, de Boer W, Bollweg K, Bolmont J, Borgia B, Borsini S, Boschini MJ, Boudoul G, Bourquin M, Brun P, Buénerd M, Burger J, Burger W, Cadoux F, Cai XD, Capell M, Casadei D, Casaus J, Cascioli V, Castellini G, Cernuda I, Cervelli F, Chae MJ, Chang YH, Chen AI, Chen CR, Chen H, Cheng GM, Chen HS, Cheng L, Chernoplyiokov N, Chikanian A, Choumilov E, Choutko V, Chung CH, Clark C, Clavero R, Coignet G, Commichau V, Consolandi C, Contin A, Corti C, Costado Dios MT, Coste B, Crespo D, Cui Z, Dai M, Delgado C, Della Torre S, Demirkoz B, Dennett P, Derome L, Di Falco S, Diao XH, Diago A, Djambazov L, Díaz C, von Doetinchem P, Du WJ, Dubois JM, Duperay R, Duranti M, D'Urso D, Egorov A, Eline A, Eppling FJ, Eronen T, van Es J, Esser H, Falvard A, Fiandrini E, Fiasson A, Finch E, Fisher P, Flood K, Foglio R, Fohey M, Fopp S, Fouque N, Galaktionov Y, Gallilee M, Gallin-Martel L, Gallucci G, García B, García J, García-López R, García-Tabares L, Gargiulo C, Gast H, Gebauer I, Gentile S, Gervasi M, Gillard W, Giovacchini F, Girard L, Goglov P, Gong J, Goy-Henningsen C, Grandi D, Graziani M, Grechko A, Gross A, Guerri I, de la Guía C, Guo KH, Habiby M, Haino S, Hauler F, He ZH, Heil M, Heilig J, Hermel R, Hofer H, Huang ZC, Hungerford W, Incagli M, Ionica M, Jacholkowska A, Jang WY, Jinchi H, Jongmanns M, Journet L, Jungermann L, Karpinski W, Kim GN, Kim KS, Kirn T, Kossakowski R, Koulemzine A, Kounina O, Kounine A, Koutsenko V, Krafczyk MS, Laudi E, Laurenti G, Lauritzen C, Lebedev A, Lee MW, Lee SC, Leluc C, León Vargas H, Lepareur V, Li JQ, Li Q, Li TX, Li W, Li ZH, Lipari P, Lin CH, Liu D, Liu H, Lomtadze T, Lu YS, Lucidi S, Lübelsmeyer K, Luo JZ, Lustermann W, Lv S, Madsen J, Majka R, Malinin A, Mañá C, Marín J, Martin T, Martínez G, Masciocchi F, Masi N, Maurin D, McInturff A, McIntyre P, Menchaca-Rocha A, Meng Q, Menichelli M, Mereu I, Millinger M, Mo DC, Molina M, Mott P, Mujunen A, Natale S, Nemeth P, Ni JQ, Nikonov N, Nozzoli F, Nunes P, Obermeier A, Oh S, Oliva A, Palmonari F, Palomares C, Paniccia M, Papi A, Park WH, Pauluzzi M, Pauss F, Pauw A, Pedreschi E, Pensotti S, Pereira R, Perrin E, Pessina G, Pierschel G, Pilo F, Piluso A, Pizzolotto C, Plyaskin V, Pochon J, Pohl M, Poireau V, Porter S, Pouxe J, Putze A, Quadrani L, Qi XN, Rancoita PG, Rapin D, Ren ZL, Ricol JS, Riihonen E, Rodríguez I, Roeser U, Rosier-Lees S, Rossi L, Rozhkov A, Rozza D, Sabellek A, Sagdeev R, Sandweiss J, Santos B, Saouter P, Sarchioni M, Schael S, Schinzel D, Schmanau M, Schwering G, Schulz von Dratzig A, Scolieri G, Seo ES, Shan BS, Shi JY, Shi YM, Siedenburg T, Siedling R, Son D, Spada F, Spinella F, Steuer M, Stiff K, Sun W, Sun WH, Sun XH, Tacconi M, Tang CP, Tang XW, Tang ZC, Tao L, Tassan-Viol J, Ting SC, Ting SM, Titus C, Tomassetti N, Toral F, Torsti J, Tsai JR, Tutt JC, Ulbricht J, Urban T, Vagelli V, Valente E, Vannini C, Valtonen E, Vargas Trevino M, Vaurynovich S, Vecchi M, Vergain M, Verlaat B, Vescovi C, Vialle JP, Viertel G, Volpini G, Wang D, Wang NH, Wang QL, Wang RS, Wang X, Wang ZX, Wallraff W, Weng ZL, Willenbrock M, Wlochal M, Wu H, Wu KY, Wu ZS, Xiao WJ, Xie S, Xiong RQ, Xin GM, Xu NS, Xu W, Yan Q, Yang J, Yang M, Ye QH, Yi H, Yu YJ, Yu ZQ, Zeissler S, Zhang JG, Zhang Z, Zhang MM, Zheng ZM, Zhuang HL, Zhukov V, Zichichi A, Zuccon P, Zurbach C; AMS Collaboration.

Phys Rev Lett. 2013 Apr 5;110(14):141102. Epub 2013 Apr 3.

PMID:
25166975
13.

Glucagon-like peptide-1 in the rat brain: distribution of expression and functional implication.

Gu G, Roland B, Tomaselli K, Dolman CS, Lowe C, Heilig JS.

J Comp Neurol. 2013 Jul 1;521(10):2235-61. doi: 10.1002/cne.23282.

PMID:
23238833
14.

Effect of different running modes on the morphological, biochemical, and mechanical properties of articular cartilage.

Hamann N, Zaucke F, Heilig J, Oberländer KD, Brüggemann GP, Niehoff A.

Scand J Med Sci Sports. 2014 Feb;24(1):179-88. doi: 10.1111/j.1600-0838.2012.01513.x. Epub 2012 Aug 13.

PMID:
22889098
15.

Differentiation and quantification of endogenous and recombinant-methionyl human leptin in clinical plasma samples by immunocapture/mass spectrometry.

Wang Y, Heilig JS.

J Pharm Biomed Anal. 2012 Nov;70:440-6. doi: 10.1016/j.jpba.2012.06.018. Epub 2012 Jun 26.

PMID:
22795822
16.

Aptamer-based multiplexed proteomic technology for biomarker discovery.

Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN, Carter J, Dalby AB, Eaton BE, Fitzwater T, Flather D, Forbes A, Foreman T, Fowler C, Gawande B, Goss M, Gunn M, Gupta S, Halladay D, Heil J, Heilig J, Hicke B, Husar G, Janjic N, Jarvis T, Jennings S, Katilius E, Keeney TR, Kim N, Koch TH, Kraemer S, Kroiss L, Le N, Levine D, Lindsey W, Lollo B, Mayfield W, Mehan M, Mehler R, Nelson SK, Nelson M, Nieuwlandt D, Nikrad M, Ochsner U, Ostroff RM, Otis M, Parker T, Pietrasiewicz S, Resnicow DI, Rohloff J, Sanders G, Sattin S, Schneider D, Singer B, Stanton M, Sterkel A, Stewart A, Stratford S, Vaught JD, Vrkljan M, Walker JJ, Watrobka M, Waugh S, Weiss A, Wilcox SK, Wolfson A, Wolk SK, Zhang C, Zichi D.

PLoS One. 2010 Dec 7;5(12):e15004. doi: 10.1371/journal.pone.0015004.

17.

Preparation of bacterial plasmid DNA.

Engebrecht J, Heilig JS, Brent R.

Curr Protoc Immunol. 2001 May;Chapter 10:Unit 10.3. doi: 10.1002/0471142735.im1003s27. Review.

PMID:
18432694
18.

Preparation of bacterial plasmid DNA.

Engebrecht J, Heilig JS, Brent R.

Curr Protoc Neurosci. 2001 May;Appendix 1:Appendix 1J. doi: 10.1002/0471142301.nsa01js10.

PMID:
18428441
19.

Large-scale preparation of plasmid DNA.

Heilig JS, Elbing KL, Brent R.

Curr Protoc Mol Biol. 2001 May;Chapter 1:Unit1.7. doi: 10.1002/0471142727.mb0107s41.

PMID:
18265046
20.

Photoaptamer arrays applied to multiplexed proteomic analysis.

Bock C, Coleman M, Collins B, Davis J, Foulds G, Gold L, Greef C, Heil J, Heilig JS, Hicke B, Hurst MN, Husar GM, Miller D, Ostroff R, Petach H, Schneider D, Vant-Hull B, Waugh S, Weiss A, Wilcox SK, Zichi D.

Proteomics. 2004 Mar;4(3):609-18.

PMID:
14997484
21.

Driving forces in cancer diagnostics.

Gander TR, Brody EN, Mehler RE, Heilig JS, Singer BS, Gold L.

MLO Med Lab Obs. 2003 Jan;35(1):10-6, 20; quiz 20-1. No abstract available. Erratum in: MLO Med Lab Obs. 2003 Apr;35(4):43.

PMID:
12561741
22.

One, two, infinity: genomes filled with aptamers.

Gold L, Brody E, Heilig J, Singer B.

Chem Biol. 2002 Dec;9(12):1259-64. No abstract available.

23.
24.

Genetic analysis of Drosophila larval optic nerve development.

Holmes AL, Raper RN, Heilig JS.

Genetics. 1998 Mar;148(3):1189-201.

25.

DeLIMiting development.

Curtiss J, Heilig JS.

Bioessays. 1998 Jan;20(1):58-69. Review.

PMID:
9504048
26.
27.

Testing the power of belief.

Heilig JS.

Science. 1997 May 9;276(5314):881. No abstract available.

PMID:
9163028
28.
29.

Isolation and characterization of the disconnected gene of Drosophila melanogaster.

Heilig JS, Freeman M, Laverty T, Lee KJ, Campos AR, Rubin GM, Steller H.

EMBO J. 1991 Apr;10(4):809-15.

30.
31.

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes.

Heilig JS, Tonegawa S.

Nature. 1986 Aug 28-Sep 3;322(6082):836-40.

PMID:
2943999
32.

Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants.

Heilig JS, Glimcher LH, Kranz DM, Clayton LK, Greenstein JL, Saito H, Maxam AM, Burakoff SJ, Eisen HN, Tonegawa S.

Nature. 1985 Sep 5-11;317(6032):68-70.

PMID:
2412133
33.

Unusual organization and diversity of T-cell receptor alpha-chain genes.

Hayday AC, Diamond DJ, Tanigawa G, Heilig JS, Folsom V, Saito H, Tonegawa S.

Nature. 1985 Aug 29-Sep 4;316(6031):828-32.

PMID:
2993907
34.
35.

Calcium hydroxide pulpotomy for primary teeth: a clinical study.

Heilig J, Yates J, Siskin M, McKnight J, Turner J.

J Am Dent Assoc. 1984 May;108(5):775-8.

PMID:
6588119
36.

Gene for the RNA polymerase sigma subunit mapped in Salmonella typhimurium and Escherichia coli by cloning and deletion.

Scaife JG, Heilig JS, Rowen L, Calendar R.

Proc Natl Acad Sci U S A. 1979 Dec;76(12):6510-4.

37.

Temperature-sensitive Escherichia coli mutant producing a temperature-sensitive sigma subunit of DNA-dependent RNA polymerase.

Harris JD, Heilig JS, Martinez II, Calendar R, Isaksson LA.

Proc Natl Acad Sci U S A. 1978 Dec;75(12):6177-81.

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