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Items: 1 to 50 of 290

1.

Distribution of Small Molecular Weight Drugs into the Porcine Lens: Studies on Imaging Mass Spectrometry, Partition Coefficients, and Implications in Ocular Pharmacokinetics.

Heikkinen EM, Auriola S, Ranta VP, Demarais NJ, Grey AC, Del Amo EM, Toropainen E, Vellonen KS, Urtti A, Ruponen M.

Mol Pharm. 2019 Sep 3;16(9):3968-3976. doi: 10.1021/acs.molpharmaceut.9b00585. Epub 2019 Aug 8.

2.

The impact of an adaptation course on health-related quality of life and functional capacity of patients with inflammatory bowel disease.

Haapamäki J, Heikkinen E, Sipponen T, Roine RP, Arkkila P.

Scand J Gastroenterol. 2018 Sep;53(9):1074-1078. doi: 10.1080/00365521.2018.1500639. Epub 2018 Sep 2.

PMID:
30175636
3.

Esterase activity in porcine and albino rabbit ocular tissues.

Heikkinen EM, Del Amo EM, Ranta VP, Urtti A, Vellonen KS, Ruponen M.

Eur J Pharm Sci. 2018 Oct 15;123:106-110. doi: 10.1016/j.ejps.2018.07.034. Epub 2018 Jul 17.

4.

Dielectric properties and carbothermic reduction of zinc oxide and zinc ferrite by microwave heating.

Omran M, Fabritius T, Heikkinen EP, Chen G.

R Soc Open Sci. 2017 Sep 20;4(9):170710. doi: 10.1098/rsos.170710. eCollection 2017 Sep.

5.

Chemical Characterization of Gas- and Particle-Phase Products from the Ozonolysis of α-Pinene in the Presence of Dimethylamine.

Duporté G, Riva M, Parshintsev J, Heikkinen E, Barreira LMF, Myllys N, Heikkinen L, Hartonen K, Kulmala M, Ehn M, Riekkola ML.

Environ Sci Technol. 2017 May 16;51(10):5602-5610. doi: 10.1021/acs.est.6b06231. Epub 2017 May 4.

PMID:
28422480
6.

Pharmacokinetic aspects of retinal drug delivery.

Del Amo EM, Rimpelä AK, Heikkinen E, Kari OK, Ramsay E, Lajunen T, Schmitt M, Pelkonen L, Bhattacharya M, Richardson D, Subrizi A, Turunen T, Reinisalo M, Itkonen J, Toropainen E, Casteleijn M, Kidron H, Antopolsky M, Vellonen KS, Ruponen M, Urtti A.

Prog Retin Eye Res. 2017 Mar;57:134-185. doi: 10.1016/j.preteyeres.2016.12.001. Epub 2016 Dec 24. Review.

7.

Foetal Fentanyl Exposure and Ion Trapping after Intravenous and Transdermal Administration to the Ewe.

Heikkinen EM, Kokki H, Heikkinen A, Ranta VP, Räsänen J, Voipio HM, Kokki M.

Basic Clin Pharmacol Toxicol. 2017 Feb;120(2):195-198. doi: 10.1111/bcpt.12665. Epub 2016 Oct 26.

8.

Event-related brain potentials to change in the frequency and temporal structure of sounds in typically developing 5-6-year-old children.

Ervast L, Hämäläinen JA, Zachau S, Lohvansuu K, Heinänen K, Veijola M, Heikkinen E, Suominen K, Luotonen M, Lehtihalmes M, Leppänen PH.

Int J Psychophysiol. 2015 Dec;98(3 Pt 1):413-25. doi: 10.1016/j.ijpsycho.2015.08.007. Epub 2015 Sep 2.

PMID:
26342552
9.

Survival and its predictors from age 75 to 85 in men and women belonging to cohorts with marked survival differences to age 75: a comparative study in three Nordic populations.

Heikkinen E, Kauppinen M, Schroll M, Steen B, Era P.

Aging Clin Exp Res. 2016 Jun;28(3):541-50. doi: 10.1007/s40520-015-0418-0. Epub 2015 Aug 9.

PMID:
26254793
10.

Fentanyl Pharmacokinetics in Pregnant Sheep after Intravenous and Transdermal Administration to the Ewe.

Heikkinen EM, Voipio HM, Laaksonen S, Haapala L, Räsänen J, Acharya G, Erkinaro T, Haapsamo M, Hautajärvi H, Kokki H, Kokki M, Heikkinen AT.

Basic Clin Pharmacol Toxicol. 2015 Sep;117(3):156-63. doi: 10.1111/bcpt.12382. Epub 2015 Feb 20.

11.

Enhancement of brain event-related potentials to speech sounds is associated with compensated reading skills in dyslexic children with familial risk for dyslexia.

Lohvansuu K, Hämäläinen JA, Tanskanen A, Ervast L, Heikkinen E, Lyytinen H, Leppänen PH.

Int J Psychophysiol. 2014 Dec;94(3):298-310. doi: 10.1016/j.ijpsycho.2014.10.002. Epub 2014 Oct 12.

PMID:
25312203
12.

Expression of VEGF and collagen XVIII in meningiomas: correlations with histopathological and MRI characteristics.

Salokorpi N, Yrjänä S, Tuominen H, Karttunen A, Heljasvaara R, Pihlajaniemi T, Heikkinen E, Koivukangas J.

Acta Neurochir (Wien). 2013 Jun;155(6):989-96; discussion 996. doi: 10.1007/s00701-013-1699-8. Epub 2013 Apr 20.

PMID:
23605255
13.

Stereotactic operations using the o-arm.

Katisko JP, Kauppinen MT, Koivukangas JP, Heikkinen ER.

Stereotact Funct Neurosurg. 2012;90(6):401-9. doi: 10.1159/000341699. Epub 2012 Oct 17.

14.

The current state and developments in higher education in gerontology in the nordic countries.

Hietanen H, Lyyra TM, Parkatti T, Heikkinen E.

Gerontol Geriatr Educ. 2012;33(2):218-31. doi: 10.1080/02701960.2011.611555.

PMID:
22490076
15.

[Update on current care guidelines. Parkinson's disease].

Reijo M, Atula S, Heikkinen E, Jaakkola MR, Pekka J, Keränen T, Martikainen K, Pekkonen E, Sotaniemi K; Suomalaisen Lääkäriseuran Duodecimin ja Suomen Neurologisen Yhdistyksen Asettama Työryhmä.

Duodecim. 2010;126(19):2289-90. Finnish.

PMID:
21086687
16.

Quality of life and barriers in the urban outdoor environment in old age.

Rantakokko M, Iwarsson S, Kauppinen M, Leinonen R, Heikkinen E, Rantanen T.

J Am Geriatr Soc. 2010 Nov;58(11):2154-9. doi: 10.1111/j.1532-5415.2010.03143.x.

PMID:
21054297
17.

Factors associated with maximal walking speed among older community-living adults.

Sallinen J, Mänty M, Leinonen R, Kallinen M, Törmäkangas T, Heikkinen E, Rantanen T.

Aging Clin Exp Res. 2011 Aug;23(4):273-8. doi: 10.3275/7270. Epub 2010 Sep 28.

PMID:
20881453
18.

Unmet physical activity need in old age.

Rantakokko M, Iwarsson S, Hirvensalo M, Leinonen R, Heikkinen E, Rantanen T.

J Am Geriatr Soc. 2010 Apr;58(4):707-12. doi: 10.1111/j.1532-5415.2010.02792.x.

PMID:
20398151
19.

Cohort differences in health, functioning and physical activity in the young-old Finnish population.

Heikkinen E, Kauppinen M, Rantanen T, Leinonen R, Lyyra TM, Suutama T, Heikkinen RL.

Aging Clin Exp Res. 2011 Apr;23(2):126-34. doi: 10.3275/6932. Epub 2010 Mar 18.

PMID:
20308805
20.

Mobility performance and its sensory, psychomotor and musculoskeletal determinants from age 75 to age 80.

Sakari R, Era P, Rantanen T, Leskinen E, Laukkanen P, Heikkinen E.

Aging Clin Exp Res. 2010 Feb;22(1):47-53.

PMID:
20305367
21.

Perceived constraints on physical exercise among obese and non-obese older people.

Sallinen J, Leinonen R, Hirvensalo M, Lyyra TM, Heikkinen E, Rantanen T.

Prev Med. 2009 Dec;49(6):506-10. doi: 10.1016/j.ypmed.2009.10.001. Epub 2009 Oct 13.

PMID:
19833148
22.

Fear of moving outdoors and development of outdoor walking difficulty in older people.

Rantakokko M, Mänty M, Iwarsson S, Törmäkangas T, Leinonen R, Heikkinen E, Rantanen T.

J Am Geriatr Soc. 2009 Apr;57(4):634-40. doi: 10.1111/j.1532-5415.2009.02180.x.

PMID:
19392955
23.

Physical activity history and end-of-life hospital and long-term care.

von Bonsdorff MB, Rantanen T, Leinonen R, Kujala UM, Törmäkangas T, Mänty M, Heikkinen E.

J Gerontol A Biol Sci Med Sci. 2009 Jul;64(7):778-84. doi: 10.1093/gerona/glp029. Epub 2009 Apr 6.

PMID:
19349592
24.

Effect of physical activity counseling on home care use in older people.

von Bonsdorff MB, Leinonen R, Kujala UM, Heikkinen E, Törmäkangas T, Hirvensalo M, Rasinaho M, Karhula S, Mänty M, Rantanen T.

J Am Geriatr Soc. 2009 Mar;57(3):571-3. doi: 10.1111/j.1532-5415.2009.02163.x. No abstract available.

PMID:
19278409
25.

Long-term effect of physical activity counseling on mobility limitation among older people: a randomized controlled study.

Mänty M, Heinonen A, Leinonen R, Törmäkangas T, Hirvensalo M, Kallinen M, Sakari R, von Bonsdorff MB, Heikkinen E, Rantanen T.

J Gerontol A Biol Sci Med Sci. 2009 Jan;64(1):83-9. doi: 10.1093/gerona/gln029. Epub 2009 Jan 20.

26.

Effect of physical activity counseling on disability in older people: a 2-year randomized controlled trial.

von Bonsdorff MB, Leinonen R, Kujala UM, Heikkinen E, Törmäkangas T, Hirvensalo M, Rasinaho M, Karhula S, Mänty M, Rantanen T.

J Am Geriatr Soc. 2008 Dec;56(12):2188-94. doi: 10.1111/j.1532-5415.2008.02000.x.

PMID:
19093917
27.

Bordetella pertussis isolates in Finland: serotype and fimbrial expression.

Heikkinen E, Xing DK, Olander RM, Hytönen J, Viljanen MK, Mertsola J, He Q.

BMC Microbiol. 2008 Sep 25;8:162. doi: 10.1186/1471-2180-8-162.

28.

Peripheral arterial disease and its clinical significance in nonagenarians.

Suominen V, Rantanen T, Heikkinen E, Venermo M, Salenius J.

Aging Clin Exp Res. 2008 Jun;20(3):211-5.

PMID:
18594188
29.

Factors affecting the increased risk of physical inactivity among older people with depressive symptoms.

Rosqvist E, Heikkinen E, Lyyra TM, Hirvensalo M, Kallinen M, Leinonen R, Rasinaho M, Pakkala I, Rantanen T.

Scand J Med Sci Sports. 2009 Jun;19(3):398-405. doi: 10.1111/j.1600-0838.2008.00798.x. Epub 2009 May 22.

PMID:
18503493
30.

Visual acuity and mortality in older people and factors on the pathway.

Kulmala J, Era P, Törmäkangas T, Pärssinen O, Rantanen T, Heikkinen E.

Ophthalmic Epidemiol. 2008 Mar-Apr;15(2):128-34. doi: 10.1080/09286580701840388.

PMID:
18432497
31.

Cortical electroencephalogram from subcortical electrodes rather than electrosubcorticogram.

Jäntti V, Heikkinen E, Alahuhta S, Remes R, Suominen K.

Anesthesiology. 2008 May;108(5):963-4; author reply 964-5. doi: 10.1097/ALN.0b013e31816bbdcf. No abstract available.

PMID:
18431134
32.

Lowered vision as a risk factor for injurious accidents in older people.

Kulmala J, Era P, Pärssinen O, Sakari R, Sipilä S, Rantanen T, Heikkinen E.

Aging Clin Exp Res. 2008 Feb;20(1):25-30.

PMID:
18283225
33.

Self-rated health and mortality in older men and women: a time-dependent covariate analysis.

Lyyra TM, Leskinen E, Jylhä M, Heikkinen E.

Arch Gerontol Geriatr. 2009 Jan-Feb;48(1):14-8. Epub 2007 Oct 22.

PMID:
17950481
34.

Comparative genomics of Bordetella pertussis reveals progressive gene loss in Finnish strains.

Heikkinen E, Kallonen T, Saarinen L, Sara R, King AJ, Mooi FR, Soini JT, Mertsola J, He Q.

PLoS One. 2007 Sep 19;2(9):e904.

35.

Genetic effects in common on maximal walking speed and muscle performance in older women.

Tiainen K, Pajala S, Sipilä S, Kaprio J, Koskenvuo M, Alén M, Heikkinen E, Tolvanen A, Rantanen T.

Scand J Med Sci Sports. 2007 Jun;17(3):274-80.

PMID:
17501868
36.

Customer-oriented counseling for physical activity in older people: study protocol and selected baseline results of a randomized-controlled trial (ISRCTN 07330512).

Leinonen R, Heikkinen E, Hirvensalo M, Lintunen T, Rasinaho M, Sakari-Rantala R, Kallinen M, Koski J, Möttönen S, Kannas S, Huovinen P, Rantanen T.

Scand J Med Sci Sports. 2007 Apr;17(2):156-64.

PMID:
17394477
37.

Parkinsonin tauti.

Marttila R, Heikkinen E, Hänninen J, Jousilahti P, Jäättelä A, Kaakkola S, Keränen T, Sotaniemi K, Teräväinen H.

Duodecim. 2006;122(21):2655-6. Finnish. No abstract available.

PMID:
17233345
38.

Fall-related injuries among initially 75- and 80-year old people during a 10-year follow-up.

Saari P, Heikkinen E, Sakari-Rantala R, Rantanen T.

Arch Gerontol Geriatr. 2007 Sep-Oct;45(2):207-15. Epub 2006 Dec 20.

PMID:
17184857
39.

Absent pedal pulse and impaired balance in older people: a cross-sectional and longitudinal study.

Suominen V, Salenius J, Heikkinen E, Heikkinen M, Rantanen T.

Aging Clin Exp Res. 2006 Oct;18(5):388-93.

PMID:
17167303
40.

Physical activity compensates for increased mortality risk among older people with poor muscle strength.

Portegijs E, Rantanen T, Sipilä S, Laukkanen P, Heikkinen E.

Scand J Med Sci Sports. 2007 Oct;17(5):473-9. Epub 2006 Dec 13.

PMID:
17166169
41.

Low-field MR imaging of meningiomas including dynamic contrast enhancement study: evaluation of surgical and histopathologic characteristics.

Yrjänä SK, Tuominen H, Karttunen A, Lähdesluoma N, Heikkinen E, Koivukangas J.

AJNR Am J Neuroradiol. 2006 Nov-Dec;27(10):2128-34.

42.

Motor speed and lower extremity strength as predictors of fall-related bone fractures in elderly individuals.

Shigematsu R, Rantanen T, Saari P, Sakari-Rantala R, Kauppinen M, Sipilä S, Heikkinen E.

Aging Clin Exp Res. 2006 Aug;18(4):320-4.

PMID:
17063067
43.

Activity as a predictor of mental well-being among older adults.

Lampinen P, Heikkinen RL, Kauppinen M, Heikkinen E.

Aging Ment Health. 2006 Sep;10(5):454-66.

PMID:
16938681
44.

Mobility limitations and cognitive deficits as predictors of institutionalization among community-dwelling older people.

von Bonsdorff M, Rantanen T, Laukkanen P, Suutama T, Heikkinen E.

Gerontology. 2006;52(6):359-65. Epub 2006 Aug 11.

PMID:
16905887
45.

The predictive value of exercise testing for survival among 75-year-old men and women.

Kallinen M, Kauppinen M, Era P, Heikkinen E.

Scand J Med Sci Sports. 2006 Aug;16(4):237-44.

PMID:
16895528
46.

Subthalamic nucleus deep brain stimulation does not alter long-term heart rate variability in Parkinson's disease.

Erola T, Haapaniemi T, Heikkinen E, Huikuri H, Myllyä V.

Clin Auton Res. 2006 Aug;16(4):286-8. Epub 2006 Jun 21.

PMID:
16791409
47.

A paradigm shift: from disease to health orientation.

Heikkinen E.

Aging Male. 2000 Dec;3(4):171-6.

PMID:
16760022
48.

Cardiac autonomic control in patients with refractory epilepsy before and during vagus nerve stimulation treatment: a one-year follow-up study.

Ronkainen E, Korpelainen JT, Heikkinen E, Myllylä VV, Huikuri HV, Isojärvi JI.

Epilepsia. 2006 Mar;47(3):556-62.

49.

Endogenous hormones, muscle strength, and risk of fall-related fractures in older women.

Sipilä S, Heikkinen E, Cheng S, Suominen H, Saari P, Kovanen V, Alén M, Rantanen T.

J Gerontol A Biol Sci Med Sci. 2006 Jan;61(1):92-6.

PMID:
16456199
50.

Efficacy of bilateral subthalamic nucleus (STN) stimulation in Parkinson's disease.

Erola T, Heikkinen ER, Haapaniemi T, Tuominen J, Juolasmaa A, Myllylä VV.

Acta Neurochir (Wien). 2006 Apr;148(4):389-94. Epub 2005 Nov 14.

PMID:
16284705

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