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Items: 1 to 50 of 89

1.

Embracing the Diversity of Halogen Bonding Motifs in Fragment-Based Drug Discovery-Construction of a Diversity-Optimized Halogen-Enriched Fragment Library.

Heidrich J, Sperl LE, Boeckler FM.

Front Chem. 2019 Feb 18;7:9. doi: 10.3389/fchem.2019.00009. eCollection 2019.

2.

Scaffold Effects on Halogen Bonding Strength.

Lange A, Heidrich J, Zimmermann MO, Exner TE, Boeckler FM.

J Chem Inf Model. 2019 Feb 25;59(2):885-894. doi: 10.1021/acs.jcim.8b00621. Epub 2019 Jan 28.

PMID:
30629432
3.

Predicting the Magnitude of σ-Holes Using VmaxPred, a Fast and Efficient Tool Supporting the Application of Halogen Bonds in Drug Discovery.

Heidrich J, Exner TE, Boeckler FM.

J Chem Inf Model. 2019 Feb 25;59(2):636-643. doi: 10.1021/acs.jcim.8b00622. Epub 2019 Jan 28.

PMID:
30582814
4.

Switching Between Bicyclic and Linear Peptides - The Sulfhydryl-Specific Linker TPSMB Enables Reversible Cyclization of Peptides.

Ernst C, Heidrich J, Sessler C, Sindlinger J, Schwarzer D, Koch P, Boeckler FM.

Front Chem. 2018 Oct 16;6:484. doi: 10.3389/fchem.2018.00484. eCollection 2018.

5.

Carbon dioxide CT angiography during endovascular treatment of bilateral common iliac disease with angio-CT utilisation.

Heidrich J, Nguyen J, Florescu C, Steward A.

J Med Imaging Radiat Oncol. 2018 Dec;62(6):798-802. doi: 10.1111/1754-9485.12799. Epub 2018 Sep 19.

PMID:
30230265
6.

Mg2+ binding triggers rearrangement of the IM30 ring structure, resulting in augmented exposure of hydrophobic surfaces competent for membrane binding.

Heidrich J, Junglas B, Grytsyk N, Hellmann N, Rusitzka K, Gebauer W, Markl J, Hellwig P, Schneider D.

J Biol Chem. 2018 May 25;293(21):8230-8241. doi: 10.1074/jbc.RA117.000991. Epub 2018 Apr 4.

7.

Detection Rates of Ductal Carcinoma in Situ with Biennial Digital Mammography Screening: Radiologic Findings Support Pathologic Model of Tumor Progression.

Weigel S, Khil L, Hense HW, Decker T, Wellmann J, Heidrich J, Sommer A, Heidinger O, Heindel W.

Radiology. 2018 Feb;286(2):424-432. doi: 10.1148/radiol.2017170673. Epub 2017 Nov 6.

PMID:
29106821
8.

A Janus-Faced IM30 Ring Involved in Thylakoid Membrane Fusion Is Assembled from IM30 Tetramers.

Saur M, Hennig R, Young P, Rusitzka K, Hellmann N, Heidrich J, Morgner N, Markl J, Schneider D.

Structure. 2017 Sep 5;25(9):1380-1390.e5. doi: 10.1016/j.str.2017.07.001. Epub 2017 Aug 10.

9.

Digital mammography screening: sensitivity of the programme dependent on breast density.

Weigel S, Heindel W, Heidrich J, Hense HW, Heidinger O.

Eur Radiol. 2017 Jul;27(7):2744-2751. doi: 10.1007/s00330-016-4636-4. Epub 2016 Nov 7.

PMID:
27822617
10.

Specific interaction of IM30/Vipp1 with cyanobacterial and chloroplast membranes results in membrane remodeling and eventually in membrane fusion.

Heidrich J, Thurotte A, Schneider D.

Biochim Biophys Acta Biomembr. 2017 Apr;1859(4):537-549. doi: 10.1016/j.bbamem.2016.09.025. Epub 2016 Sep 30. Review.

11.

Regular exercise behaviour and intention and symptoms of anxiety and depression in coronary heart disease patients across Europe: Results from the EUROASPIRE III survey.

Prugger C, Wellmann J, Heidrich J, De Bacquer D, De Smedt D, De Backer G, Reiner Ž, Empana JP, Fras Z, Gaita D, Jennings C, Kotseva K, Wood D, Keil U; EUROASPIRE Study Group.

Eur J Prev Cardiol. 2017 Jan;24(1):84-91. Epub 2016 Sep 1.

12.

Trends in advanced breast cancer incidence rates after implementation of a mammography screening program in a German population.

Simbrich A, Wellmann I, Heidrich J, Heidinger O, Hense HW.

Cancer Epidemiol. 2016 Oct;44:44-51. doi: 10.1016/j.canep.2016.07.006. Epub 2016 Jul 25.

13.

Organization into Higher Ordered Ring Structures Counteracts Membrane Binding of IM30, a Protein Associated with Inner Membranes in Chloroplasts and Cyanobacteria.

Heidrich J, Wulf V, Hennig R, Saur M, Markl J, Sönnichsen C, Schneider D.

J Biol Chem. 2016 Jul 15;291(29):14954-62. doi: 10.1074/jbc.M116.722686. Epub 2016 May 20.

14.

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

Fechner U, de Graaf C, Torda AE, Güssregen S, Evers A, Matter H, Hessler G, Richmond NJ, Schmidtke P, Segler MHS, Waller MP, Pleik S, Shea JE, Levine Z, Mullen R, van den Broek K, Epple M, Kuhn H, Truszkowski A, Zielesny A, Fraaije JH, Gracia RS, Kast SM, Bulusu KC, Bender A, Yosipof A, Nahum O, Senderowitz H, Krotzky T, Schulz R, Wolber G, Bietz S, Rarey M, Zimmermann MO, Lange A, Ruff M, Heidrich J, Onlia I, Exner TE, Boeckler FM, Bermudez M, Firaha DS, Hollóczki O, Kirchner B, Tautermann CS, Volkamer A, Eid S, Turk S, Rippmann F, Fulle S, Saleh N, Saladino G, Gervasio FL, Haensele E, Banting L, Whitley DC, Oliveira Santos JS, Bureau R, Clark T, Sandmann A, Lanig H, Kibies P, Heil J, Hoffgaard F, Frach R, Engel J, Smith S, Basu D, Rauh D, Kohlbacher O, Boeckler FM, Essex JW, Bodnarchuk MS, Ross GA, Finkelmann AR, Göller AH, Schneider G, Husch T, Schütter C, Balducci A, Korth M, Ntie-Kang F, Günther S, Sippl W, Mbaze LM, Ntie-Kang F, Simoben CV, Lifongo LL, Ntie-Kang F, Judson P, Barilla J, Lokajíček MV, Pisaková H, Simr P, Kireeva N, Petrov A, Ostroumov D, Solovev VP, Pervov VS, Friedrich NO, Sommer K, Rarey M, Kirchmair J, Proschak E, Weber J, Moser D, Kalinowski L, Achenbach J, Mackey M, Cheeseright T, Renner G, Renner G, Schmidt TC, Schram J, Egelkraut-Holtus M, van Oeyen A, Kalliokoski T, Fourches D, Ibezim A, Mbah CJ, Adikwu UM, Nwodo NJ, Steudle A, Masek BB, Nagy S, Baker D, Soltanshahi F, Dorfman R, Dubrucq K, Patel H, Koch O, Mrugalla F, Kast SM, Ain QU, Fuchs JE, Owen RM, Omoto K, Torella R, Pryde DC, Glen R, Bender A, Hošek P, Spiwok V, Mervin LH, Barrett I, Firth M, Murray DC, McWilliams L, Cao Q, Engkvist O, Warszycki D, Śmieja M, Bojarski AJ, Aniceto N, Freitas A, Ghafourian T, Herrmann G, Eigner-Pitto V, Naß A, Kurczab R, Bojarski AJ, Lange A, Günther MB, Hennig S, Büttner FM, Schall C, Sievers-Engler A, Ansideri F, Koch P, Stehle T, Laufer S, Böckler FM, Zdrazil B, Montanari F, Ecker GF, Grebner C, Hogner A, Ulander J, Edman K, Guallar V, Tyrchan C, Ulander J, Tyrchan C, Klute W, Bergström F, Kramer C, Nguyen QD, Frach R, Kibies P, Strohfeldt S, Böttcher S, Pongratz T, Horinek D, Kast SM, Rupp B, Al-Yamori R, Lisurek M, Kühne R, Furtado F, van den Broek K, Wessjohann L, Mathea M, Baumann K, Mohamad-Zobir SZ, Fu X, Fan TP, Bender A, Kuhn MA, Sotriffer CA, Zoufir A, Li X, Mervin L, Berg E, Polokoff M, Ihlenfeldt WD, Ihlenfeldt WD, Pretzel J, Alhalabi Z, Fraczkiewicz R, Waldman M, Clark RD, Shaikh N, Garg P, Kos A, Himmler HJ, Sandmann A, Jardin C, Sticht H, Steinbrecher TB, Dahlgren M, Cappel D, Lin T, Wang L, Krilov G, Abel R, Friesner R, Sherman W, Pöhner IA, Panecka J, Wade RC, Bietz S, Schomburg KT, Hilbig M, Rarey M, Jäger C, Wieczorek V, Westerhoff LM, Borbulevych OY, Demuth HU, Buchholz M, Schmidt D, Rickmeyer T, Krotzky T, Kolb P, Mittal S, Sánchez-García E, Nogueira MS, Oliveira TB, da Costa FB, Schmidt TJ.

J Cheminform. 2016 Apr 26;8(Suppl 1):18. doi: 10.1186/s13321-016-0119-5. No abstract available.

15.

Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond.

Lange A, Günther M, Büttner FM, Zimmermann MO, Heidrich J, Hennig S, Zahn S, Schall C, Sievers-Engler A, Ansideri F, Koch P, Laemmerhofer M, Stehle T, Laufer SA, Boeckler FM.

J Am Chem Soc. 2015 Nov 25;137(46):14640-52. doi: 10.1021/jacs.5b07090. Epub 2015 Nov 12.

PMID:
26505827
16.

Digital Mammography Screening: Does Age Influence the Detection Rates of Low-, Intermediate-, and High-Grade Ductal Carcinoma in Situ?

Weigel S, Hense HW, Heidrich J, Berkemeyer S, Heindel W, Heidinger O.

Radiology. 2016 Mar;278(3):707-13. doi: 10.1148/radiol.2015150322. Epub 2015 Oct 27.

PMID:
26505802
17.

Reduction of Advanced Breast Cancer Stages at Subsequent Participation in Mammography Screening.

Weigel S, Heindel W, Heidrich J, Heidinger O, Hense HW.

Rofo. 2016 Jan;188(1):33-7. doi: 10.1055/s-0041-107835. Epub 2015 Oct 20.

18.

Modifying Behaviors in Patients With Coronary Heart Disease.

Behrens T, Heidrich J, Keil U.

Dtsch Arztebl Int. 2015 Jun 26;112(26):459. doi: 10.3238/arztebl.2015.0459a. No abstract available.

19.

One-pot synthesis of human metabolites of SAR548304 by fungal peroxygenases.

Kiebist J, Holla W, Heidrich J, Poraj-Kobielska M, Sandvoss M, Simonis R, Gröbe G, Atzrodt J, Hofrichter M, Scheibner K.

Bioorg Med Chem. 2015 Aug 1;23(15):4324-32. doi: 10.1016/j.bmc.2015.06.035. Epub 2015 Jun 19.

PMID:
26142319
20.

IM30 triggers membrane fusion in cyanobacteria and chloroplasts.

Hennig R, Heidrich J, Saur M, Schmüser L, Roeters SJ, Hellmann N, Woutersen S, Bonn M, Weidner T, Markl J, Schneider D.

Nat Commun. 2015 May 8;6:7018. doi: 10.1038/ncomms8018.

PMID:
25952141
21.

Digital mammography screening in Germany: Impact of age and histological subtype on program sensitivity.

Heidinger O, Heidrich J, Batzler WU, Krieg V, Weigel S, Heindel W, Hense HW.

Breast. 2015 Jun;24(3):191-6. doi: 10.1016/j.breast.2014.12.009. Epub 2015 Feb 14.

PMID:
25687106
22.

Readiness for smoking cessation in coronary heart disease patients across Europe: Results from the EUROASPIRE III survey.

Prugger C, Wellmann J, Heidrich J, De Bacquer D, De Backer G, Périer MC, Empana JP, Reiner Ž, Fras Z, Jennings C, Kotseva K, Wood D, Keil U; EUROASPIRE Study Group.

Eur J Prev Cardiol. 2015 Sep;22(9):1212-9. doi: 10.1177/2047487314564728. Epub 2014 Dec 16.

23.

Control of main risk factors after ischaemic stroke across Europe: data from the stroke-specific module of the EUROASPIRE III survey.

Heuschmann PU, Kircher J, Nowe T, Dittrich R, Reiner Z, Cifkova R, Malojcic B, Mayer O, Bruthans J, Wloch-Kopec D, Prugger C, Heidrich J, Keil U.

Eur J Prev Cardiol. 2015 Oct;22(10):1354-62. doi: 10.1177/2047487314546825. Epub 2014 Aug 19.

PMID:
25139770
24.

Optical and SPION-enhanced MR imaging shows that trans-stilbene inhibitors of NF-κB concomitantly lower Alzheimer's disease plaque formation and microglial activation in AβPP/PS-1 transgenic mouse brain.

Solberg NO, Chamberlin R, Vigil JR, Deck LM, Heidrich JE, Brown DC, Brady CI, Vander Jagt TA, Garwood M, Bisoffi M, Severns V, Vander Jagt DL, Sillerud LO.

J Alzheimers Dis. 2014;40(1):191-212. doi: 10.3233/JAD-131031.

25.

Passive smoking and smoking cessation among patients with coronary heart disease across Europe: results from the EUROASPIRE III survey.

Prugger C, Wellmann J, Heidrich J, De Bacquer D, Perier MC, Empana JP, Reiner Ž, Fras Z, Jennings C, Kotseva K, Wood D, Keil U; EUROASPIRE Study Group.

Eur Heart J. 2014 Mar;35(9):590-8. doi: 10.1093/eurheartj/eht538. Epub 2013 Dec 13.

PMID:
24334711
26.

SPION-enhanced magnetic resonance imaging of Alzheimer's disease plaques in AβPP/PS-1 transgenic mouse brain.

Sillerud LO, Solberg NO, Chamberlain R, Orlando RA, Heidrich JE, Brown DC, Brady CI, Vander Jagt TA, Garwood M, Vander Jagt DL.

J Alzheimers Dis. 2013;34(2):349-65. doi: 10.3233/JAD-121171.

27.

Influenza virus infection in nonhuman primates.

Karlsson EA, Engel GA, Feeroz MM, San S, Rompis A, Lee BP, Shaw E, Oh G, Schillaci MA, Grant R, Heidrich J, Schultz-Cherry S, Jones-Engel L.

Emerg Infect Dis. 2012 Oct;18(10):1672-5. doi: 10.3201/eid1810.120214.

28.

Trends in cardiovascular risk factors among patients with coronary heart disease: results from the EUROASPIRE I, II, and III surveys in the Münster region.

Prugger C, Heidrich J, Wellmann J, Dittrich R, Brand SM, Telgmann R, Breithardt G, Reinecke H, Scheld H, Kleine-Katthöfer P, Heuschmann PU, Keil U.

Dtsch Arztebl Int. 2012 Apr;109(17):303-10. doi: 10.3238/arztebl.2012.0303. Epub 2012 Apr 27.

29.

Depression, anxiety, and risk factor control in patients after hospitalization for coronary heart disease: the EUROASPIRE III Study.

Pająk A, Jankowski P, Kotseva K, Heidrich J, de Smedt D, De Bacquer D; EUROASPIRE Study Group.

Eur J Prev Cardiol. 2013 Apr;20(2):331-40. doi: 10.1177/2047487312441724. Epub 2012 Mar 6.

PMID:
22396247
30.

Barriers to guideline implementation.

Behrens T, Keil U, Heidrich J.

Dtsch Arztebl Int. 2011 Jul;108(28-29):491; author reply 493. doi: 10.3238/arztebl.2011.0491a. Epub 2011 Jul 18. No abstract available.

31.

Blood pressure control and knowledge of target blood pressure in coronary patients across Europe: results from the EUROASPIRE III survey.

Prugger C, Keil U, Wellmann J, de Bacquer D, de Backer G, Ambrosio GB, Reiner Z, Gaita D, Wood D, Kotseva K, Heidrich J; EUROASPIRE III Study Group.

J Hypertens. 2011 Aug;29(8):1641-8. doi: 10.1097/HJH.0b013e328348efa7.

PMID:
21720270
32.

Gender differences in the implementation of cardiovascular prevention measures after an acute coronary event.

Dallongevillle J, De Bacquer D, Heidrich J, De Backer G, Prugger C, Kotseva K, Montaye M, Amouyel P; EUROASPIRE Study Group.

Heart. 2010 Nov;96(21):1744-9. doi: 10.1136/hrt.2010.196170.

PMID:
20956490
33.

Management of overweight and obese patients with coronary heart disease across Europe.

De Bacquer D, Dallongeville J, Heidrich J, Kotseva K, Reiner Z, Gaita D, Prugger C, Wellmann J, Wood D, De Backer G, Keil U; EUROASPIRE III Study Group.

Eur J Cardiovasc Prev Rehabil. 2010 Aug;17(4):447-54. doi: 10.1097/HJR.0b013e328336a05f.

PMID:
20485181
34.

Synanthropic primates in Asia: potential sentinels for environmental toxins.

Engel G, O'Hara TM, Cardona-Marek T, Heidrich J, Chalise MK, Kyes R, Jones-Engel L.

Am J Phys Anthropol. 2010 Jul;142(3):453-60. doi: 10.1002/ajpa.21247.

35.

Improving antithrombotic management in patients with atrial fibrillation: current status and perspectives.

Levi M, Hobbs FD, Jacobson AK, Pisters R, Prisco D, Bernardo A, Haas M, Heidrich J, Rosenberg M, Nielsen JD, Wuillemin WA.

Semin Thromb Hemost. 2009 Sep;35(6):527-42. doi: 10.1055/s-0029-1240013. Epub 2009 Sep 28.

PMID:
19787556
36.

The efficacy of erythropoietin and its analogues in animal stroke models: a meta-analysis.

Minnerup J, Heidrich J, Rogalewski A, Schäbitz WR, Wellmann J.

Stroke. 2009 Sep;40(9):3113-20. doi: 10.1161/STROKEAHA.109.555789. Epub 2009 Jun 18. Review.

PMID:
19542052
37.

Experimental ELISA for diagnosis of ovine dicrocoeliosis and application in a field survey.

Broglia A, Heidrich J, Lanfranchi P, Nöckler K, Schuster R.

Parasitol Res. 2009 Mar;104(4):949-53. doi: 10.1007/s00436-008-1315-7. Epub 2008 Dec 24.

PMID:
19107521
38.

Cardiovascular risk factors and mortality in patients with coronary heart disease.

Prugger C, Wellmann J, Heidrich J, Brand-Herrmann SM, Keil U.

Eur J Epidemiol. 2008;23(11):731-7. doi: 10.1007/s10654-008-9291-x. Epub 2008 Oct 15.

PMID:
18855105
39.

Thoracic radiography of pet macaques in Sulawesi, Indonesia.

Schillaci MA, Jones-Engel L, Heidrich JE, Benamore R, Pereira A, Paul N.

J Med Primatol. 2008 Jun;37(3):141-5. doi: 10.1111/j.1600-0684.2007.00250.x.

PMID:
18547258
40.

Meta-analysis of the efficacy of granulocyte-colony stimulating factor in animal models of focal cerebral ischemia.

Minnerup J, Heidrich J, Wellmann J, Rogalewski A, Schneider A, Schäbitz WR.

Stroke. 2008 Jun;39(6):1855-61. doi: 10.1161/STROKEAHA.107.506816. Epub 2008 Apr 10.

PMID:
18403735
41.

Stroke mortality and morbidity attributable to passive smoking in Germany.

Heuschmann PU, Heidrich J, Wellmann J, Kraywinkel K, Keil U.

Eur J Cardiovasc Prev Rehabil. 2007 Dec;14(6):793-5.

PMID:
18043301
42.

Alcohol consumption, alcohol dehydrogenase and risk of coronary heart disease in the MONICA/KORA-Augsburg cohort 1994/1995-2002.

Heidrich J, Wellmann J, Döring A, Illig T, Keil U.

Eur J Cardiovasc Prev Rehabil. 2007 Dec;14(6):769-74.

PMID:
18043297
43.

Liver flukes in dogs and treatment with praziquantel.

Schuster RK, Heidrich J, Pauly A, Nöckler K.

Vet Parasitol. 2007 Dec 25;150(4):362-5. Epub 2007 Nov 5.

PMID:
17981396
44.

Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease.

Bertilsson G, Patrone C, Zachrisson O, Andersson A, Dannaeus K, Heidrich J, Kortesmaa J, Mercer A, Nielsen E, Rönnholm H, Wikström L.

J Neurosci Res. 2008 Feb 1;86(2):326-38.

PMID:
17803225
45.

Mortality and morbidity from coronary heart disease attributable to passive smoking.

Heidrich J, Wellmann J, Heuschmann PU, Kraywinkel K, Keil U.

Eur Heart J. 2007 Oct;28(20):2498-502. Epub 2007 May 15.

PMID:
17507368
46.

Stroke risk perception among participants of a stroke awareness campaign.

Kraywinkel K, Heidrich J, Heuschmann PU, Wagner M, Berger K.

BMC Public Health. 2007 Mar 20;7:39.

47.

Variations in the use of diagnostic procedures after acute stroke in Europe: results from the BIOMED II study of stroke care.

Heidrich J, Heuschmann PU, Kolominsky-Rabas P, Rudd AG, Wolfe CD; European BIOMED II Study of Stroke Care Group.

Eur J Neurol. 2007 Mar;14(3):255-61.

PMID:
17355544
48.

Considering human-primate transmission of measles virus through the prism of risk analysis.

Jones-Engel L, Engel GA, Schillaci MA, Lee B, Heidrich J, Chalise M, Kyes RC.

Am J Primatol. 2006 Sep;68(9):868-79.

PMID:
16900498
49.

Temple monkeys and health implications of commensalism, Kathmandu, Nepal.

Jones-Engel L, Engel GA, Heidrich J, Chalise M, Poudel N, Viscidi R, Barry PA, Allan JS, Grant R, Kyes R.

Emerg Infect Dis. 2006 Jun;12(6):900-6.

50.

Genetic characterization of rhesus macaques (Macaca mulatta) in Nepal.

Kyes RC, Jones-Engel L, Chalise MK, Engel G, Heidrich J, Grant R, Bajimaya SS, McDonough J, Smith DG, Ferguson B.

Am J Primatol. 2006 May;68(5):445-55.

PMID:
16541441

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