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Items: 1 to 50 of 66

1.

Global Proteome of LonP1+/- Mouse Embryonal Fibroblasts Reveals Impact on Respiratory Chain, but No Interdependence between Eral1 and Mitoribosomes.

Key J, Kohli A, Bárcena C, López-Otín C, Heidler J, Wittig I, Auburger G.

Int J Mol Sci. 2019 Sep 12;20(18). pii: E4523. doi: 10.3390/ijms20184523.

2.

Nitric oxide maintains endothelial redox homeostasis through PKM2 inhibition.

Siragusa M, Thöle J, Bibli SI, Luck B, Loot AE, de Silva K, Wittig I, Heidler J, Stingl H, Randriamboavonjy V, Kohlstedt K, Brüne B, Weigert A, Fisslthaler B, Fleming I.

EMBO J. 2019 Sep 2;38(17):e100938. doi: 10.15252/embj.2018100938. Epub 2019 Jul 22.

PMID:
31328803
3.

Myeloid-Specific Deletion of the AMPKα2 Subunit Alters Monocyte Protein Expression and Atherogenesis.

Fisslthaler B, Zippel N, Abdel Malik R, Delgado Lagos F, Zukunft S, Thoele J, Siuda D, Soehnlein O, Wittig I, Heidler J, Weigert A, Fleming I.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E3005. doi: 10.3390/ijms20123005.

4.

Design guidelines for an electron diffractometer for structural chemistry and structural biology.

Heidler J, Pantelic R, Wennmacher JTC, Zaubitzer C, Fecteau-Lefebvre A, Goldie KN, Müller E, Holstein JJ, van Genderen E, De Carlo S, Gruene T.

Acta Crystallogr D Struct Biol. 2019 May 1;75(Pt 5):458-466. doi: 10.1107/S2059798319003942. Epub 2019 Apr 8.

5.

TLR2-Dependent Reversible Oxidation of Connexin 43 at Cys260 Modifies Electrical Coupling After Experimental Myocardial Ischemia/Reperfusion.

Raimann FJ, Dröse S, Bonke E, Schneider L, Tybl E, Wittig I, Heidler J, Heide H, Josipovic I, Leisegang M, Brandes RP, Roeper J, Zacharowski K, Mersmann J.

J Cardiovasc Transl Res. 2019 Oct;12(5):478-487. doi: 10.1007/s12265-019-09887-0. Epub 2019 Apr 8.

PMID:
30963423
6.

BIAM switch assay coupled to mass spectrometry identifies novel redox targets of NADPH oxidase 4.

Löwe O, Rezende F, Heidler J, Wittig I, Helfinger V, Brandes RP, Schröder K.

Redox Biol. 2019 Feb;21:101125. doi: 10.1016/j.redox.2019.101125. Epub 2019 Jan 29.

7.

Deep proteome of human nNOS/NOS1-positive versus MOCK SH-SY5Y neuroblastoma cells under full nutrition, serum free starvation and rapamycin treatment.

Heidler J, Valek L, Wittig I, Tegeder I.

Data Brief. 2018 Oct 26;21:1309-1314. doi: 10.1016/j.dib.2018.10.079. eCollection 2018 Dec.

8.

Redox-proteomes of human NOS1-transduced versus MOCK SH-SY5Y neuroblastoma cells under full nutrition, serum-free starvation, and rapamycin treatment.

Heidler J, Valek L, Wittig I, Tegeder I.

Data Brief. 2018 Oct 26;21:1302-1308. doi: 10.1016/j.dib.2018.10.078. eCollection 2018 Dec.

9.

Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D.

Valek L, Heidler J, Scheving R, Wittig I, Tegeder I.

Redox Biol. 2019 Jan;20:217-235. doi: 10.1016/j.redox.2018.10.002. Epub 2018 Oct 16.

10.

Rapid Structure Determination of Microcrystalline Molecular Compounds Using Electron Diffraction.

Gruene T, Wennmacher JTC, Zaubitzer C, Holstein JJ, Heidler J, Fecteau-Lefebvre A, De Carlo S, Müller E, Goldie KN, Regeni I, Li T, Santiso-Quinones G, Steinfeld G, Handschin S, van Genderen E, van Bokhoven JA, Clever GH, Pantelic R.

Angew Chem Int Ed Engl. 2018 Dec 10;57(50):16313-16317. doi: 10.1002/anie.201811318. Epub 2018 Nov 15.

11.

The terpenes of leaves, pollen, and nectar of thyme (Thymus vulgaris) inhibit growth of bee disease-associated microbes.

Wiese N, Fischer J, Heidler J, Lewkowski O, Degenhardt J, Erler S.

Sci Rep. 2018 Oct 2;8(1):14634. doi: 10.1038/s41598-018-32849-6.

12.

Bi-allelic Mutations in NDUFA6 Establish Its Role in Early-Onset Isolated Mitochondrial Complex I Deficiency.

Alston CL, Heidler J, Dibley MG, Kremer LS, Taylor LS, Fratter C, French CE, Glasgow RIC, Feichtinger RG, Delon I, Pagnamenta AT, Dolling H, Lemonde H, Aiton N, Bjørnstad A, Henneke L, Gärtner J, Thiele H, Tauchmannova K, Quaghebeur G, Houstek J, Sperl W, Raymond FL, Prokisch H, Mayr JA, McFarland R, Poulton J, Ryan MT, Wittig I, Henneke M, Taylor RW.

Am J Hum Genet. 2018 Oct 4;103(4):592-601. doi: 10.1016/j.ajhg.2018.08.013. Epub 2018 Sep 20.

13.

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis.

Bibli SI, Hu J, Sigala F, Wittig I, Heidler J, Zukunft S, Tsilimigras DI, Randriamboavonjy V, Wittig J, Kojonazarov B, Schürmann C, Siragusa M, Siuda D, Luck B, Abdel Malik R, Filis KA, Zografos G, Chen C, Wang DW, Pfeilschifter J, Brandes RP, Szabo C, Papapetropoulos A, Fleming I.

Circulation. 2019 Jan 2;139(1):101-114. doi: 10.1161/CIRCULATIONAHA.118.034757.

PMID:
29970364
14.

Metabolic Maturation during Muscle Stem Cell Differentiation Is Achieved by miR-1/133a-Mediated Inhibition of the Dlk1-Dio3 Mega Gene Cluster.

Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T.

Cell Metab. 2018 May 1;27(5):1026-1039.e6. doi: 10.1016/j.cmet.2018.02.022. Epub 2018 Apr 5.

15.

Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.

Lampe S, Kunze M, Scholz A, Brauß TF, Winslow S, Simm S, Keller M, Heidler J, Wittig I, Brüne B, Schmid T.

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):147-157. doi: 10.1016/j.bbagrm.2018.01.010. Epub 2018 Jan 31. No abstract available.

PMID:
29378331
16.

Acyl modification and binding of mitochondrial ACP to multiprotein complexes.

Angerer H, Schönborn S, Gorka J, Bahr U, Karas M, Wittig I, Heidler J, Hoffmann J, Morgner N, Zickermann V.

Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1913-1920. doi: 10.1016/j.bbamcr.2017.08.006. Epub 2017 Aug 9.

17.

Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex.

Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D.

Mol Biol Cell. 2017 Aug 9. pii: mbc.E17-02-0093. doi: 10.1091/mbc.E17-02-0093. [Epub ahead of print]

18.

Loss of synaptic zinc transport in progranulin deficient mice may contribute to progranulin-associated psychopathology and chronic pain.

Hardt S, Heidler J, Albuquerque B, Valek L, Altmann C, Wilken-Schmitz A, Schäfer MKE, Wittig I, Tegeder I.

Biochim Biophys Acta Mol Basis Dis. 2017 Nov;1863(11):2727-2745. doi: 10.1016/j.bbadis.2017.07.014. Epub 2017 Jul 15.

19.

Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy.

Roos J, Peters M, Maucher IV, Kühn B, Fettel J, Hellmuth N, Brat C, Sommer B, Urbschat A, Piesche M, Vogel A, Proschak E, Blöcher R, Buscató E, Häfner AK, Matrone C, Werz O, Heidler J, Wittig I, Angioni C, Geisslinger G, Parnham MJ, Zacharowski K, Steinhilber D, Maier TJ.

Antioxid Redox Signal. 2018 May 10;28(14):1265-1285. doi: 10.1089/ars.2017.7155. Epub 2017 Sep 8.

PMID:
28699354
20.

Conserved and species-specific molecular denominators in mammalian skeletal muscle aging.

Mercken EM, Capri M, Carboneau BA, Conte M, Heidler J, Santoro A, Martin-Montalvo A, Gonzalez-Freire M, Khraiwesh H, González-Reyes JA, Moaddel R, Zhang Y, Becker KG, Villalba JM, Mattison JA, Wittig I, Franceschi C, de Cabo R.

NPJ Aging Mech Dis. 2017 May 5;3:8. doi: 10.1038/s41514-017-0009-8. eCollection 2017.

21.

Rab7-a novel redox target that modulates inflammatory pain processing.

Kallenborn-Gerhardt W, Möser CV, Lorenz JE, Steger M, Heidler J, Scheving R, Petersen J, Kennel L, Flauaus C, Lu R, Edinger AL, Tegeder I, Geisslinger G, Heide H, Wittig I, Schmidtko A.

Pain. 2017 Jul;158(7):1354-1365. doi: 10.1097/j.pain.0000000000000920.

PMID:
28394828
22.

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.

Leisegang MS, Fork C, Josipovic I, Richter FM, Preussner J, Hu J, Miller MJ, Epah J, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ Jr, Brandes RP.

Circulation. 2017 Jul 4;136(1):65-79. doi: 10.1161/CIRCULATIONAHA.116.026991. Epub 2017 Mar 28.

23.

Halogen-bond-based cooperative ion-pair recognition by a crown-ether-embedded 5-iodo-1,2,3-triazole.

Tepper R, Schulze B, Bellstedt P, Heidler J, Görls H, Jäger M, Schubert US.

Chem Commun (Camb). 2017 Feb 14;53(14):2260-2263. doi: 10.1039/c6cc09749a.

PMID:
28150008
24.

Enhanced Nonadiabaticity in Vortex Cores due to the Emergent Hall Effect.

Bisig A, Akosa CA, Moon JH, Rhensius J, Moutafis C, von Bieren A, Heidler J, Kiliani G, Kammerer M, Curcic M, Weigand M, Tyliszczak T, Van Waeyenberge B, Stoll H, Schütz G, Lee KJ, Manchon A, Kläui M.

Phys Rev Lett. 2016 Dec 30;117(27):277203. doi: 10.1103/PhysRevLett.117.277203. Epub 2016 Dec 30.

PMID:
28084754
25.

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.

Szibor M, Dhandapani PK, Dufour E, Holmström KM, Zhuang Y, Salwig I, Wittig I, Heidler J, Gizatullina Z, Gainutdinov T; German Mouse Clinic Consortium, Fuchs H, Gailus-Durner V, de Angelis MH, Nandania J, Velagapudi V, Wietelmann A, Rustin P, Gellerich FN, Jacobs HT, Braun T.

Dis Model Mech. 2017 Feb 1;10(2):163-171. doi: 10.1242/dmm.027839. Epub 2016 Dec 14.

26.
27.

A Bak-dependent mitochondrial amplification step contributes to Smac mimetic/glucocorticoid-induced necroptosis.

Rohde K, Kleinesudeik L, Roesler S, Löwe O, Heidler J, Schröder K, Wittig I, Dröse S, Fulda S.

Cell Death Differ. 2017 Jan;24(1):83-97. doi: 10.1038/cdd.2016.102. Epub 2016 Nov 11.

28.

AMP-Activated Protein Kinase α2 in Neutrophils Regulates Vascular Repair via Hypoxia-Inducible Factor-1α and a Network of Proteins Affecting Metabolism and Apoptosis.

Abdel Malik R, Zippel N, Frömel T, Heidler J, Zukunft S, Walzog B, Ansari N, Pampaloni F, Wingert S, Rieger MA, Wittig I, Fisslthaler B, Fleming I.

Circ Res. 2017 Jan 6;120(1):99-109. doi: 10.1161/CIRCRESAHA.116.309937. Epub 2016 Oct 24.

29.

Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling.

Altmann C, Vasic V, Hardt S, Heidler J, Häussler A, Wittig I, Schmidt MHH, Tegeder I.

Mol Neurodegener. 2016 Oct 22;11(1):69.

30.

Progranulin overexpression in sensory neurons attenuates neuropathic pain in mice: Role of autophagy.

Altmann C, Hardt S, Fischer C, Heidler J, Lim HY, Häussler A, Albuquerque B, Zimmer B, Möser C, Behrends C, Koentgen F, Wittig I, Schmidt MHH, Clement AM, Deller T, Tegeder I.

Neurobiol Dis. 2016 Dec;96:294-311. doi: 10.1016/j.nbd.2016.09.010. Epub 2016 Sep 11.

PMID:
27629805
31.

Ciprofloxacin: pH-dependent SERS signal and its detection in spiked river water using LoC-SERS.

Hidi IJ, Heidler J, Weber K, Cialla-May D, Popp J.

Anal Bioanal Chem. 2016 Nov;408(29):8393-8401. Epub 2016 Oct 3.

PMID:
27699451
32.

Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue.

Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, Kley RA, Barkovits K, Strecker V, Berwanger C, Herrmann H, Marcus K, Kornblum C, Kunz WS, Schröder R, Clemen CS.

Acta Neuropathol. 2016 Sep;132(3):453-73. doi: 10.1007/s00401-016-1592-7. Epub 2016 Jul 8.

33.
34.

Supercomplex-associated Cox26 protein binds to cytochrome c oxidase.

Strecker V, Kadeer Z, Heidler J, Cruciat CM, Angerer H, Giese H, Pfeiffer K, Stuart RA, Wittig I.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1643-52. doi: 10.1016/j.bbamcr.2016.04.012. Epub 2016 Apr 16.

35.

S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.

Stathopoulou K, Wittig I, Heidler J, Piasecki A, Richter F, Diering S, van der Velden J, Buck F, Donzelli S, Schröder E, Wijnker PJ, Voigt N, Dobrev D, Sadayappan S, Eschenhagen T, Carrier L, Eaton P, Cuello F.

FASEB J. 2016 May;30(5):1849-64. doi: 10.1096/fj.201500048. Epub 2016 Feb 2.

36.

Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.

Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, Schnütgen F, Scheibe S, Seimetz M, Jaksch P, Hyman A, Weissmann N, von Melchner H.

J Biol Chem. 2015 Apr 10;290(15):9738-52. doi: 10.1074/jbc.M114.632133. Epub 2015 Feb 25.

37.

Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.

Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E.

Methods Mol Biol. 2015;1264:245-61. doi: 10.1007/978-1-4939-2257-4_22.

PMID:
25631019
38.

Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD.

Heidler J, Fysikopoulos A, Wempe F, Seimetz M, Bangsow T, Tomasovic A, Veit F, Scheibe S, Pichl A, Weisel F, Lloyd KC, Jaksch P, Klepetko W, Weissmann N, von Melchner H.

Dis Model Mech. 2013 Nov;6(6):1378-87. doi: 10.1242/dmm.013482. Epub 2013 Aug 29.

39.

Quantification of protein complexes by blue native electrophoresis.

Heidler J, Strecker V, Csintalan F, Bleier L, Wittig I.

Methods Mol Biol. 2013;1033:363-79. doi: 10.1007/978-1-62703-487-6_23.

PMID:
23996189
40.

Correlation between spin structure oscillations and domain wall velocities.

Bisig A, Stärk M, Mawass MA, Moutafis C, Rhensius J, Heidler J, Büttner F, Noske M, Weigand M, Eisebitt S, Tyliszczak T, Van Waeyenberge B, Stoll H, Schütz G, Kläui M.

Nat Commun. 2013;4:2328. doi: 10.1038/ncomms3328.

41.

The effect of magnetic anisotropy on the spin configurations of patterned La(0.7)Sr(0.3)MnO3 elements.

Wohlhüter P, Rhensius J, Vaz CA, Heidler J, Körner HS, Bisig A, Foerster M, Méchin L, Gaucher F, Locatelli A, Niño MA, El Moussaoui S, Nolting F, Goering E, Heyderman LJ, Kläui M.

J Phys Condens Matter. 2013 May 1;25(17):176004. doi: 10.1088/0953-8984/25/17/176004. Epub 2013 Apr 8.

PMID:
23567900
42.

[Costs of delivering allogenic blood in hospitals].

Hönemann C, Bierbaum M, Heidler J, Doll D, Schöffski O.

Chirurg. 2013 May;84(5):426-32. doi: 10.1007/s00104-012-2464-x. German.

PMID:
23519380
43.

Antioxidant activity of sestrin 2 controls neuropathic pain after peripheral nerve injury.

Kallenborn-Gerhardt W, Lu R, Syhr KM, Heidler J, von Melchner H, Geisslinger G, Bangsow T, Schmidtko A.

Antioxid Redox Signal. 2013 Dec 10;19(17):2013-23. doi: 10.1089/ars.2012.4958. Epub 2013 Apr 19.

44.

Optimal ferromagnetically-coated carbon nanotube tips for ultra-high resolution magnetic force microscopy.

Lisunova Y, Heidler J, Levkivskyi I, Gaponenko I, Weber A, Caillier Ch, Heyderman LJ, Kläui M, Paruch P.

Nanotechnology. 2013 Mar 15;24(10):105705. doi: 10.1088/0957-4484/24/10/105705. Epub 2013 Feb 20.

PMID:
23426040
45.

The mitochondrial genome of the venomous cone snail Conus consors.

Brauer A, Kurz A, Stockwell T, Baden-Tillson H, Heidler J, Wittig I, Kauferstein S, Mebs D, Stöcklin R, Remm M.

PLoS One. 2012;7(12):e51528. doi: 10.1371/journal.pone.0051528. Epub 2012 Dec 7.

46.

X-Treme beamline at SLS: X-ray magnetic circular and linear dichroism at high field and low temperature.

Piamonteze C, Flechsig U, Rusponi S, Dreiser J, Heidler J, Schmidt M, Wetter R, Calvi M, Schmidt T, Pruchova H, Krempasky J, Quitmann C, Brune H, Nolting F.

J Synchrotron Radiat. 2012 Sep;19(Pt 5):661-74. doi: 10.1107/S0909049512027847. Epub 2012 Jul 21.

PMID:
22898943
47.

Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany.

Peiser M, Tralau T, Heidler J, Api AM, Arts JH, Basketter DA, English J, Diepgen TL, Fuhlbrigge RC, Gaspari AA, Johansen JD, Karlberg AT, Kimber I, Lepoittevin JP, Liebsch M, Maibach HI, Martin SF, Merk HF, Platzek T, Rustemeyer T, Schnuch A, Vandebriel RJ, White IR, Luch A.

Cell Mol Life Sci. 2012 Mar;69(5):763-81. doi: 10.1007/s00018-011-0846-8. Epub 2011 Oct 14. Review.

48.

Two-spinon and orbital excitations of the spin-Peierls system TiOCl.

Glawion S, Heidler J, Haverkort MW, Duda LC, Schmitt T, Strocov VN, Monney C, Zhou KJ, Ruff A, Sing M, Claessen R.

Phys Rev Lett. 2011 Sep 2;107(10):107402. Epub 2011 Sep 1. Erratum in: Phys Rev Lett. 2011 Sep 16;107(12):129902.

PMID:
21981527
49.

Nitric oxide-associated protein 1 (NOA1) is necessary for oxygen-dependent regulation of mitochondrial respiratory complexes.

Heidler J, Al-Furoukh N, Kukat C, Salwig I, Ingelmann ME, Seibel P, Krüger M, Holtz J, Wittig I, Braun T, Szibor M.

J Biol Chem. 2011 Sep 16;286(37):32086-93. doi: 10.1074/jbc.M111.221986. Epub 2011 Jul 19.

50.

Photoemission of a doped Mott insulator: spectral weight transfer and a qualitative Mott-Hubbard description.

Sing M, Glawion S, Schlachter M, Scholz MR, Goss K, Heidler J, Berner G, Claessen R.

Phys Rev Lett. 2011 Feb 4;106(5):056403. Epub 2011 Feb 4.

PMID:
21405415

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