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Items: 1 to 50 of 82

1.

Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group.

Cohen KJ, Heideman RL, Zhou T, Holmes EJ, Lavey RS, Bouffet E, Pollack IF.

Neuro Oncol. 2011 Apr;13(4):410-6. doi: 10.1093/neuonc/noq205. Epub 2011 Feb 22.

2.

Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group.

Cohen KJ, Pollack IF, Zhou T, Buxton A, Holmes EJ, Burger PC, Brat DJ, Rosenblum MK, Hamilton RL, Lavey RS, Heideman RL.

Neuro Oncol. 2011 Mar;13(3):317-23. doi: 10.1093/neuonc/noq191.

3.

Extended phase I evaluation of vincristine, irinotecan, temozolomide, and antibiotic in children with refractory solid tumors.

McNall-Knapp RY, Williams CN, Reeves EN, Heideman RL, Meyer WH.

Pediatr Blood Cancer. 2010 Jul 1;54(7):909-15. doi: 10.1002/pbc.22460.

PMID:
20405511
4.

Two new patients with Curry-Jones syndrome with trichoblastoma and medulloblastoma suggest an etiologic role of the sonic hedgehog-patched-GLI pathway.

Grange DK, Clericuzio CL, Bayliss SJ, Berk DR, Heideman RL, Higginson JK, Julian S, Lind A.

Am J Med Genet A. 2008 Oct 15;146A(20):2589-97. doi: 10.1002/ajmg.a.32503.

PMID:
18798318
5.

Risk determinants for catheter-associated blood stream infections in children and young adults with cancer.

Allen RC, Holdsworth MT, Johnson CA, Chavez CM, Heideman RL, Overturf G, Lemon D, Hunt WC, Winter SS.

Pediatr Blood Cancer. 2008 Jul;51(1):53-8. doi: 10.1002/pbc.21497.

PMID:
18266227
6.

Successful treatment of an unresectable choroid plexus carcinoma in a patient with Li-Fraumeni syndrome.

Dickens DS, Dothage JA, Heideman RL, Ballard ET, Jubinsky PT.

J Pediatr Hematol Oncol. 2005 Jan;27(1):46-9.

PMID:
15654279
7.

Clinically evident venous thromboembolic events in children with brain tumors.

Deitcher SR, Gajjar A, Kun L, Heideman RL.

J Pediatr. 2004 Dec;145(6):848-50.

PMID:
15580217
8.

Early neuro-otologic effects of three-dimensional irradiation in children with primary brain tumors.

Merchant TE, Gould CJ, Xiong X, Robbins N, Zhu J, Pritchard DL, Khan R, Heideman RL, Krasin MJ, Kun LE.

Int J Radiat Oncol Biol Phys. 2004 Mar 15;58(4):1194-207.

PMID:
15001264
9.

Phase 2 study of idarubicin in pediatric brain tumors: Pediatric Oncology Group study POG 9237.

Dreyer ZE, Kadota RP, Stewart CF, Friedman HS, Mahoney DH, Kun LE, McCluggage CW, Burger PC, Kepner J, Heideman RL; Pediatric Oncology Group.

Neuro Oncol. 2003 Oct;5(4):261-7.

10.

Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.

Panetta JC, Kirstein MN, Gajjar A, Nair G, Fouladi M, Heideman RL, Wilkinson M, Stewart CF.

Cancer Chemother Pharmacol. 2003 Dec;52(6):435-41. Epub 2003 Sep 16.

PMID:
13680158
11.

Survival and functional outcome of children with hypothalamic/chiasmatic tumors.

Fouladi M, Wallace D, Langston JW, Mulhern R, Rose SR, Gajjar A, Sanford RA, Merchant TE, Jenkins JJ, Kun LE, Heideman RL.

Cancer. 2003 Feb 15;97(4):1084-92.

12.

Altered irinotecan pharmacokinetics in pediatric high-grade glioma patients receiving enzyme-inducing anticonvulsant therapy.

Crews KR, Stewart CF, Jones-Wallace D, Thompson SJ, Houghton PJ, Heideman RL, Fouladi M, Bowers DC, Chintagumpala MM, Gajjar A.

Clin Cancer Res. 2002 Jul;8(7):2202-9.

13.

Influence of tumor grade on time to progression after irradiation for localized ependymoma in children.

Merchant TE, Jenkins JJ, Burger PC, Sanford RA, Sherwood SH, Jones-Wallace D, Heideman RL, Thompson SJ, Helton KJ, Kun LE.

Int J Radiat Oncol Biol Phys. 2002 May 1;53(1):52-7.

PMID:
12007941
14.

Preliminary results from a Phase II trail of conformal radiation therapy for pediatric patients with localised low-grade astrocytoma and ependymoma.

Merchant TE, Zhu Y, Thompson SJ, Sontag MR, Heideman RL, Kun LE.

Int J Radiat Oncol Biol Phys. 2002 Feb 1;52(2):325-32.

PMID:
11872277
15.

Phase I study of combination topotecan and carboplatin in pediatric solid tumors.

Athale UH, Stewart C, Kuttesch JF, Moghrabi A, Meyer W, Pratt C, Gajjar A, Heideman RL.

J Clin Oncol. 2002 Jan 1;20(1):88-95.

PMID:
11773158
16.

Overview of the treatment of infant central nervous system tumors: medulloblastoma as a model.

Heideman RL.

J Pediatr Hematol Oncol. 2001 Jun-Jul;23(5):268-71. Review. No abstract available.

PMID:
11464980
17.

Immediate neurocognitive effects of methylphenidate on learning-impaired survivors of childhood cancer.

Thompson SJ, Leigh L, Christensen R, Xiong X, Kun LE, Heideman RL, Reddick WE, Gajjar A, Merchant T, Pui CH, Hudson MM, Mulhern RK.

J Clin Oncol. 2001 Mar 15;19(6):1802-8.

PMID:
11251012
18.

Tamoxifen and carboplatin for children with low-grade gliomas: a pilot study at St. Jude Children's Research Hospital.

Walter AW, Gajjar A, Reardon DA, Thompson SJ, Langston JW, Jones-Wallace D, Kun LE, Heideman RL.

J Pediatr Hematol Oncol. 2000 May-Jun;22(3):247-51.

PMID:
10864056
19.

Pediatric choroid plexus neoplasms.

Chow E, Reardon DA, Shah AB, Jenkins JJ, Langston J, Heideman RL, Sanford RA, Kun LE, Merchant TE.

Int J Radiat Oncol Biol Phys. 1999 May 1;44(2):249-54.

PMID:
10760416
20.

Malignant evolution of choroid plexus papilloma.

Chow E, Jenkins JJ, Burger PC, Reardon DA, Langston JW, Sanford RA, Heideman RL, Kun LE, Merchant TE.

Pediatr Neurosurg. 1999 Sep;31(3):127-30.

PMID:
10708353
21.

Diagnosis of hidden central hypothyroidism in survivors of childhood cancer.

Rose SR, Lustig RH, Pitukcheewanont P, Broome DC, Burghen GA, Li H, Hudson MM, Kun LE, Heideman RL.

J Clin Endocrinol Metab. 1999 Dec;84(12):4472-9.

PMID:
10599705
22.

Survival and neurodevelopmental outcome of young children with medulloblastoma at St Jude Children's Research Hospital.

Walter AW, Mulhern RK, Gajjar A, Heideman RL, Reardon D, Sanford RA, Xiong X, Kun LE.

J Clin Oncol. 1999 Dec;17(12):3720-8.

PMID:
10577843
23.

Comparison of lumbar and shunt cerebrospinal fluid specimens for cytologic detection of leptomeningeal disease in pediatric patients with brain tumors.

Gajjar A, Fouladi M, Walter AW, Thompson SJ, Reardon DA, Merchant TE, Jenkins JJ, Liu A, Boyett JM, Kun LE, Heideman RL.

J Clin Oncol. 1999 Jun;17(6):1825-8.

PMID:
10561221
24.

Comparison of CSF cytology and spinal magnetic resonance imaging in the detection of leptomeningeal disease in pediatric medulloblastoma or primitive neuroectodermal tumor.

Fouladi M, Gajjar A, Boyett JM, Walter AW, Thompson SJ, Merchant TE, Jenkins JJ, Langston JW, Liu A, Kun LE, Heideman RL.

J Clin Oncol. 1999 Oct;17(10):3234-7.

PMID:
10506624
25.

Topotecan for the treatment of recurrent or progressive central nervous system tumors - a pediatric oncology group phase II study.

Kadota RP, Stewart CF, Horn M, Kuttesch JF Jr, Burger PC, Kepner JL, Kun LE, Friedman HS, Heideman RL.

J Neurooncol. 1999 May;43(1):43-7.

PMID:
10448870
26.

Hypothalamic obesity caused by cranial insult in children: altered glucose and insulin dynamics and reversal by a somatostatin agonist.

Lustig RH, Rose SR, Burghen GA, Velasquez-Mieyer P, Broome DC, Smith K, Li H, Hudson MM, Heideman RL, Kun LE.

J Pediatr. 1999 Aug;135(2 Pt 1):162-8.

PMID:
10431109
27.

Interpatient variability in bioavailability of the intravenous formulation of topotecan given orally to children with recurrent solid tumors.

Zamboni WC, Bowman LC, Tan M, Santana VM, Houghton PJ, Meyer WH, Pratt CB, Heideman RL, Gajjar AJ, Pappo AS, Stewart CF.

Cancer Chemother Pharmacol. 1999;43(6):454-60.

PMID:
10321504
28.

O6-Methylguanine-DNA methyltransferase protein levels in pediatric brain tumors.

Hongeng S, Brent TP, Sanford RA, Li H, Kun LE, Heideman RL.

Clin Cancer Res. 1997 Dec;3(12 Pt 1):2459-63.

29.

A four-hour topotecan infusion achieves cytotoxic exposure throughout the neuraxis in the nonhuman primate model: implications for treatment of children with metastatic medulloblastoma.

Zamboni WC, Gajjar AJ, Mandrell TD, Einhaus SL, Danks MK, Rogers WP, Heideman RL, Houghton PJ, Stewart CF.

Clin Cancer Res. 1998 Oct;4(10):2537-44.

30.

Bithalamic involvement predicts poor outcome among children with thalamic glial tumors.

Reardon DA, Gajjar A, Sanford RA, Heideman RL, Walter AW, Thompson SJ, Merchant TE, Li H, Jenkins JJ, Langston J, Boyett JM, Kun LE.

Pediatr Neurosurg. 1998 Jul;29(1):29-35.

PMID:
9867348
31.

Phenytoin alters the disposition of topotecan and N-desmethyl topotecan in a patient with medulloblastoma.

Zamboni WC, Gajjar AJ, Heideman RL, Beijnen JH, Rosing H, Houghton PJ, Stewart CF.

Clin Cancer Res. 1998 Mar;4(3):783-9.

32.

Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization.

Reardon DA, Michalkiewicz E, Boyett JM, Sublett JE, Entrekin RE, Ragsdale ST, Valentine MB, Behm FG, Li H, Heideman RL, Kun LE, Shapiro DN, Look AT.

Cancer Res. 1997 Sep 15;57(18):4042-7.

33.

Cerebellar pontine angle ependymoma in infants.

Sanford RA, Kun LE, Heideman RL, Gajjar A.

Pediatr Neurosurg. 1997 Aug;27(2):84-91.

PMID:
9520080
34.

Patterns of failure in children with medulloblastoma: effects of preirradiation chemotherapy.

Hartsell WF, Gajjar A, Heideman RL, Langston JA, Sanford RA, Walter A, Jones D, Chen G, Kun LE.

Int J Radiat Oncol Biol Phys. 1997 Aug 1;39(1):15-24.

PMID:
9300735
35.

Reduced TSC2 RNA and protein in sporadic astrocytomas and ependymomas.

Wienecke R, Guha A, Maize JC Jr, Heideman RL, DeClue JE, Gutmann DH.

Ann Neurol. 1997 Aug;42(2):230-5.

PMID:
9266734
36.

Supratentorial malignant gliomas in childhood: a single institution perspective.

Heideman RL, Kuttesch J Jr, Gajjar AJ, Walter AW, Jenkins JJ, Li Y, Sanford RA, Kun LE.

Cancer. 1997 Aug 1;80(3):497-504.

PMID:
9241084
37.

Papillary thyroid carcinoma: demographics, treatment, and outcome in eleven pediatric patients treated at a single institution.

Kuefer MU, Moinuddin M, Heideman RL, Lustig RH, Rose SR, Burstein S, VanMiddlesworth L, Fleming I, Jenkins JJ, Shearer PD.

Med Pediatr Oncol. 1997 Jun;28(6):433-40.

PMID:
9143389
38.

Clinical value of proton magnetic resonance spectroscopy for differentiating recurrent or residual brain tumor from delayed cerebral necrosis.

Taylor JS, Langston JW, Reddick WE, Kingsley PB, Ogg RJ, Pui MH, Kun LE, Jenkins JJ 3rd, Chen G, Ochs JJ, Sanford RA, Heideman RL.

Int J Radiat Oncol Biol Phys. 1996 Dec 1;36(5):1251-61.

PMID:
8985051
39.

DNA index of glial tumors in children. Correlation with tumor grade and prognosis.

Mathew P, Look T, Luo X, Ashmun R, Nash M, Gajjar A, Walter A, Kun L, Heideman RL.

Cancer. 1996 Aug 15;78(4):881-6.

PMID:
8756385
40.

Phase II evaluation of topotecan for pediatric central nervous system tumors.

Blaney SM, Phillips PC, Packer RJ, Heideman RL, Berg SL, Adamson PC, Allen JC, Sallan SE, Jakacki RI, Lange BJ, Reaman GH, Horowitz ME, Poplack DG, Balis FM.

Cancer. 1996 Aug 1;78(3):527-31.

PMID:
8697400
41.

Topoisomerase I interactive drugs in children with cancer.

Stewart CF, Zamboni WC, Crom WR, Gajjar A, Heideman RL, Furman WL, Meyer WH, Houghton PJ, Pratt CB.

Invest New Drugs. 1996;14(1):37-47. Review.

PMID:
8880392
42.

Carboplatin pharmacokinetics in young children with brain tumors.

Tonda ME, Heideman RL, Petros WP, Friedman HS, Murry DJ, Rodman JH.

Cancer Chemother Pharmacol. 1996;38(5):395-400.

PMID:
8765431
43.

Cerebrospinal fluid pharmacokinetics and penetration of continuous infusion topotecan in children with central nervous system tumors.

Baker SD, Heideman RL, Crom WR, Kuttesch JF, Gajjar A, Stewart CF.

Cancer Chemother Pharmacol. 1996;37(3):195-202.

PMID:
8529278
44.
45.

Preirradiation chemotherapy with carboplatin and etoposide in newly diagnosed embryonal pediatric CNS tumors.

Heideman RL, Kovnar EH, Kellie SJ, Douglass EC, Gajjar AJ, Walter AW, Langston JA, Jenkins JJ, Li Y, Greenwald C, et al.

J Clin Oncol. 1995 Sep;13(9):2247-54.

PMID:
7666082
46.

A phase II evaluation of thiotepa followed by other multiagent chemotherapy regimens in infants and young children with malignant brain tumors.

Razzouk BI, Heideman RL, Friedman HS, Jenkins JJ, Kun LE, Fairclough DL, Horowitz ME.

Cancer. 1995 Jun 1;75(11):2762-7.

PMID:
7743483
47.

A phase II study of every other day high-dose ifosfamide in pediatric brain tumors: a Pediatric Oncology Group Study.

Heideman RL, Douglass EC, Langston JA, Krischer JP, Burger PC, Kovnar EH, Kun LE, Friedman HS, Kadota R.

J Neurooncol. 1995;25(1):77-84.

PMID:
8523093
48.

High-activity 125I interstitial irradiation in the treatment of pediatric central nervous system tumors: a pilot study.

Fontanesi J, Heideman RL, Muhlbauer M, Mulhern R, Sanford RA, Douglass EC, Kovnar E, Ochs JJ, Kuttesch JF, Tai D, et al.

Pediatr Neurosurg. 1995;22(6):289-97; discussion 98.

PMID:
7577662
49.

Clinical pharmacodynamics of continuous infusion topotecan in children: systemic exposure predicts hematologic toxicity.

Stewart CF, Baker SD, Heideman RL, Jones D, Crom WR, Pratt CB.

J Clin Oncol. 1994 Sep;12(9):1946-54.

PMID:
8083716
50.

Medulloblastoma in very young children: outcome of definitive craniospinal irradiation following incomplete response to chemotherapy.

Gajjar A, Mulhern RK, Heideman RL, Sanford RA, Douglass EC, Kovnar EH, Langston JA, Jenkins JJ, Kun LE.

J Clin Oncol. 1994 Jun;12(6):1212-6.

PMID:
8201384

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