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SHP-2 is activated in response to force on E-cadherin and dephosphorylates vinculin Y822.

Campbell H, Heidema C, Pilarczyk DG, DeMali KA.

J Cell Sci. 2018 Dec 14;131(24). pii: jcs216648. doi: 10.1242/jcs.216648.


Linking E-cadherin mechanotransduction to cell metabolism through force-mediated activation of AMPK.

Bays JL, Campbell HK, Heidema C, Sebbagh M, DeMali KA.

Nat Cell Biol. 2017 Jun;19(6):724-731. doi: 10.1038/ncb3537. Epub 2017 May 29.

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