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Items: 1 to 50 of 58

1.

The C-type Lectin Receptor CLEC12A Recognizes Plasmodial Hemozoin and Contributes to Cerebral Malaria Development.

Raulf MK, Johannssen T, Matthiesen S, Neumann K, Hachenberg S, Mayer-Lambertz S, Steinbeis F, Hegermann J, Seeberger PH, Baumgärtner W, Strube C, Ruland J, Lepenies B.

Cell Rep. 2019 Jul 2;28(1):30-38.e5. doi: 10.1016/j.celrep.2019.06.015.

2.

Diversity patterns of bacteriophages infecting Aggregatibacter and Haemophilus species across clades and niches.

Szafrański SP, Kilian M, Yang I, Bei der Wieden G, Winkel A, Hegermann J, Stiesch M.

ISME J. 2019 Jun 14. doi: 10.1038/s41396-019-0450-8. [Epub ahead of print]

PMID:
31201356
3.

A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants.

Eggenschwiler R, Patronov A, Hegermann J, Fráguas-Eggenschwiler M, Wu G, Cortnumme L, Ochs M, Antes I, Cantz T.

Sci Rep. 2019 May 16;9(1):7486. doi: 10.1038/s41598-019-44043-3.

4.

Protein O- and C-Glycosylation pathways in Toxoplasma gondii and Plasmodium falciparum.

Bandini G, Albuquerque-Wendt A, Hegermann J, Samuelson J, Routier FH.

Parasitology. 2019 Feb 18:1-12. doi: 10.1017/S0031182019000040. [Epub ahead of print]

PMID:
30773146
5.

On the Topological Complexity of Human Alveolar Epithelial Type 1 Cells.

Schneider JP, Wrede C, Hegermann J, Weibel ER, Mühlfeld C, Ochs M.

Am J Respir Crit Care Med. 2019 May 1;199(9):1153-1156. doi: 10.1164/rccm.201810-1866LE. No abstract available.

6.

Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis.

Beike L, Wrede C, Hegermann J, Lopez-Rodriguez E, Kloth C, Gauldie J, Kolb M, Maus UA, Ochs M, Knudsen L.

Lab Invest. 2019 Jun;99(6):830-852. doi: 10.1038/s41374-019-0189-x. Epub 2019 Jan 30.

PMID:
30700849
7.

Zidovudine-Mediated Autophagy Inhibition Enhances Mitochondrial Toxicity in Muscle Cells.

Lin H, Stankov MV, Hegermann J, Budida R, Panayotova-Dimitrova D, Schmidt RE, Behrens GMN.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01443-18. doi: 10.1128/AAC.01443-18. Print 2019 Jan.

8.

Air-blood barrier thickening and alterations of alveolar epithelial type 2 cells in mouse lungs with disrupted hepcidin/ferroportin regulatory system.

Mühlfeld C, Neves J, Brandenberger C, Hegermann J, Wrede C, Altamura S, Muckenthaler MU.

Histochem Cell Biol. 2019 Mar;151(3):217-228. doi: 10.1007/s00418-018-1737-y. Epub 2018 Oct 3.

PMID:
30280242
9.

oxLDL inhibits differentiation and functional activity of osteoclasts via scavenger receptor-A mediated autophagy and cathepsin K secretion.

Dawodu D, Patecki M, Hegermann J, Dumler I, Haller H, Kiyan Y.

Sci Rep. 2018 Aug 2;8(1):11604. doi: 10.1038/s41598-018-29963-w.

10.

Absence of Complex I Implicates Rearrangement of the Respiratory Chain in European Mistletoe.

Senkler J, Rugen N, Eubel H, Hegermann J, Braun HP.

Curr Biol. 2018 May 21;28(10):1606-1613.e4. doi: 10.1016/j.cub.2018.03.050. Epub 2018 May 3.

11.

ABCA3 missense mutations causing surfactant dysfunction disorders have distinct cellular phenotypes.

Schindlbeck U, Wittmann T, Höppner S, Kinting S, Liebisch G, Hegermann J, Griese M.

Hum Mutat. 2018 Jun;39(6):841-850. doi: 10.1002/humu.23416. Epub 2018 Mar 25.

PMID:
29505158
12.

1700012B09Rik, a FOXJ1 effector gene active in ciliated tissues of the mouse but not essential for motile ciliogenesis.

Stauber M, Boldt K, Wrede C, Weidemann M, Kellner M, Schuster-Gossler K, Kühnel MP, Hegermann J, Ueffing M, Gossler A.

Dev Biol. 2017 Sep 1;429(1):186-199. doi: 10.1016/j.ydbio.2017.06.027. Epub 2017 Jun 28.

13.

Autophagy in kidney transplants of sirolimus treated recipients.

Bhayana S, Baisantry A, Kraemer TD, Wrede C, Hegermann J, Bräsen JH, Bockmeyer C, Ulrich Becker J, Ochs M, Gwinner W, Haller H, Melk A, Schmitt R.

J Nephropathol. 2017 Mar;6(2):90-96. doi: 10.15171/jnp.2017.15. Epub 2016 Oct 22.

14.

Development and Characterization of a Porcine Mitral Valve Scaffold for Tissue Engineering.

Granados M, Morticelli L, Andriopoulou S, Kalozoumis P, Pflaum M, Iablonskii P, Glasmacher B, Harder M, Hegermann J, Wrede C, Tudorache I, Cebotari S, Hilfiker A, Haverich A, Korossis S.

J Cardiovasc Transl Res. 2017 Aug;10(4):374-390. doi: 10.1007/s12265-017-9747-z. Epub 2017 May 1.

PMID:
28462436
15.

CFAP157 is a murine downstream effector of FOXJ1 that is specifically required for flagellum morphogenesis and sperm motility.

Weidemann M, Schuster-Gossler K, Stauber M, Wrede C, Hegermann J, Ott T, Boldt K, Beyer T, Serth K, Kremmer E, Blum M, Ueffing M, Gossler A.

Development. 2016 Dec 15;143(24):4736-4748.

16.

Differentiation of induced pluripotent stem cell-derived neutrophil granulocytes from common marmoset monkey (Callithrix jacchus).

Schrimpf C, Wrede C, Glage S, Hegermann J, Backhaus S, Blasczyk R, Heuft HG, Müller T.

Transfusion. 2017 Jan;57(1):60-69. doi: 10.1111/trf.13909. Epub 2016 Nov 25.

PMID:
27888517
17.

The impact of autophagy on the development of senescence in primary tubular epithelial cells.

Baisantry A, Bhayana S, Wrede C, Hegermann J, Haller H, Melk A, Schmitt R.

Cell Cycle. 2016 Nov;15(21):2973-2979. Epub 2016 Oct 7.

18.

CO2 and HCO3- Permeability of the Rat Liver Mitochondrial Membrane.

Arias-Hidalgo M, Hegermann J, Tsiavaliaris G, Carta F, Supuran CT, Gros G, Endeward V.

Cell Physiol Biochem. 2016;39(5):2014-2024. Epub 2016 Oct 24.

19.

Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes.

Weber N, Schwanke K, Greten S, Wendland M, Iorga B, Fischer M, Geers-Knörr C, Hegermann J, Wrede C, Fiedler J, Kempf H, Franke A, Piep B, Pfanne A, Thum T, Martin U, Brenner B, Zweigerdt R, Kraft T.

Basic Res Cardiol. 2016 Nov;111(6):68. Epub 2016 Oct 14.

PMID:
27743117
20.

Using electron microscopes to look into the lung.

Ochs M, Knudsen L, Hegermann J, Wrede C, Grothausmann R, Mühlfeld C.

Histochem Cell Biol. 2016 Dec;146(6):695-707. doi: 10.1007/s00418-016-1502-z. Epub 2016 Sep 29. Review.

PMID:
27688057
21.

Regulation of macroautophagy in amiodarone-induced pulmonary fibrosis.

Mahavadi P, Knudsen L, Venkatesan S, Henneke I, Hegermann J, Wrede C, Ochs M, Ahuja S, Chillappagari S, Ruppert C, Seeger W, Korfei M, Guenther A.

J Pathol Clin Res. 2015 Jun 3;1(4):252-63. doi: 10.1002/cjp2.20. eCollection 2015 Oct.

22.

Tools to explore ABCA3 mutations causing interstitial lung disease.

Wittmann T, Schindlbeck U, Höppner S, Kinting S, Frixel S, Kröner C, Liebisch G, Hegermann J, Aslanidis C, Brasch F, Reu S, Lasch P, Zarbock R, Griese M.

Pediatr Pulmonol. 2016 Dec;51(12):1284-1294. doi: 10.1002/ppul.23471. Epub 2016 May 13.

PMID:
27177387
23.

Increased Risk of Interstitial Lung Disease in Children with a Single R288K Variant of ABCA3.

Wittmann T, Frixel S, Höppner S, Schindlbeck U, Schams A, Kappler M, Hegermann J, Wrede C, Liebisch G, Vierzig A, Zacharasiewicz A, Kopp MV, Poets CF, Baden W, Hartl D, van Kaam AH, Lohse P, Aslanidis C, Zarbock R, Griese M.

Mol Med. 2016 Sep;22:183-191. doi: 10.2119/molmed.2015.00244. Epub 2016 Feb 26.

24.

Visualization of the glomerular endothelial glycocalyx by electron microscopy using cationic colloidal thorium dioxide.

Hegermann J, Lünsdorf H, Ochs M, Haller H.

Histochem Cell Biol. 2016 Jan;145(1):41-51. doi: 10.1007/s00418-015-1378-3. Epub 2015 Nov 25.

PMID:
26608651
25.

MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.

Schlosser A, Pilecki B, Hemstra LE, Kejling K, Kristmannsdottir GB, Wulf-Johansson H, Moeller JB, Füchtbauer EM, Nielsen O, Kirketerp-Møller K, Dubey LK, Hansen PB, Stubbe J, Wrede C, Hegermann J, Ochs M, Rathkolb B, Schrewe A, Bekeredjian R, Wolf E, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Lindholt JS, Holmskov U, Sorensen GL.

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):122-33. doi: 10.1161/ATVBAHA.115.306672. Epub 2015 Nov 12.

PMID:
26564819
26.

Autophagy Induces Prosenescent Changes in Proximal Tubular S3 Segments.

Baisantry A, Bhayana S, Rong S, Ermeling E, Wrede C, Hegermann J, Pennekamp P, Sörensen-Zender I, Haller H, Melk A, Schmitt R.

J Am Soc Nephrol. 2016 Jun;27(6):1609-16. doi: 10.1681/ASN.2014111059. Epub 2015 Oct 20.

27.

Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance.

Schieck E, Lartigue C, Frey J, Vozza N, Hegermann J, Miller RA, Valguarnera E, Muriuki C, Meens J, Nene V, Naessens J, Weber J, Lowary TL, Vashee S, Feldman MF, Jores J.

Mol Microbiol. 2016 Jan;99(1):55-70. doi: 10.1111/mmi.13213. Epub 2015 Oct 14.

28.

A review of recent developments and applications of morphometry/stereology in lung research.

Mühlfeld C, Hegermann J, Wrede C, Ochs M.

Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15;309(6):L526-36. doi: 10.1152/ajplung.00047.2015. Epub 2015 Jul 17. Review.

29.

Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4.

Holm AT, Wulf-Johansson H, Hvidsten S, Jorgensen PT, Schlosser A, Pilecki B, Ormhøj M, Moeller JB, Johannsen C, Baun C, Andersen T, Schneider JP, Hegermann J, Ochs M, Götz AA, Schulz H, de Angelis MH, Vestbo J, Holmskov U, Sorensen GL.

Am J Physiol Lung Cell Mol Physiol. 2015 Jun 1;308(11):L1114-24. doi: 10.1152/ajplung.00351.2014. Epub 2015 Apr 10.

30.

Upk3b is dispensable for development and integrity of urothelium and mesothelium.

Rudat C, Grieskamp T, Röhr C, Airik R, Wrede C, Hegermann J, Herrmann BG, Schuster-Gossler K, Kispert A.

PLoS One. 2014 Nov 12;9(11):e112112. doi: 10.1371/journal.pone.0112112. eCollection 2014.

31.

The quantitative nuclear matrix proteome as a biochemical snapshot of nuclear organization.

Engelke R, Riede J, Hegermann J, Wuerch A, Eimer S, Dengjel J, Mittler G.

J Proteome Res. 2014 Sep 5;13(9):3940-56. doi: 10.1021/pr500218f. Epub 2014 Aug 12.

PMID:
25090448
32.

Novel magnesium alloy Mg-2La caused no cytotoxic effects on cells in physiological conditions.

Weizbauer A, Seitz JM, Werle P, Hegermann J, Willbold E, Eifler R, Windhagen H, Reifenrath J, Waizy H.

Mater Sci Eng C Mater Biol Appl. 2014 Aug 1;41:267-73. doi: 10.1016/j.msec.2014.04.063. Epub 2014 May 5.

PMID:
24907760
33.

Involvement of ClC-3 chloride/proton exchangers in controlling glutamatergic synaptic strength in cultured hippocampal neurons.

Guzman RE, Alekov AK, Filippov M, Hegermann J, Fahlke C.

Front Cell Neurosci. 2014 May 23;8:143. doi: 10.3389/fncel.2014.00143. eCollection 2014.

34.

A large kindred of pulmonary fibrosis associated with a novel ABCA3 gene variant.

Campo I, Zorzetto M, Mariani F, Kadija Z, Morbini P, Dore R, Kaltenborn E, Frixel S, Zarbock R, Liebisch G, Hegermann J, Wrede C, Griese M, Luisetti M.

Respir Res. 2014 Apr 15;15:43. doi: 10.1186/1465-9921-15-43.

35.

Two Rab2 interactors regulate dense-core vesicle maturation.

Ailion M, Hannemann M, Dalton S, Pappas A, Watanabe S, Hegermann J, Liu Q, Han HF, Gu M, Goulding MQ, Sasidharan N, Schuske K, Hullett P, Eimer S, Jorgensen EM.

Neuron. 2014 Apr 2;82(1):167-80. doi: 10.1016/j.neuron.2014.02.017.

36.

Liprin-α/SYD-2 determines the size of dense projections in presynaptic active zones in C. elegans.

Kittelmann M, Hegermann J, Goncharov A, Taru H, Ellisman MH, Richmond JE, Jin Y, Eimer S.

J Cell Biol. 2013 Dec 9;203(5):849-63. doi: 10.1083/jcb.201302022.

37.

In vivo synaptic recovery following optogenetic hyperstimulation.

Kittelmann M, Liewald JF, Hegermann J, Schultheis C, Brauner M, Steuer Costa W, Wabnig S, Eimer S, Gottschalk A.

Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E3007-16. doi: 10.1073/pnas.1305679110. Epub 2013 Jul 22.

38.

Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 in hepatocellular carcinoma.

Kirstein MM, Boukouris AE, Pothiraju D, Buitrago-Molina LE, Marhenke S, Schütt J, Orlik J, Kühnel F, Hegermann J, Manns MP, Vogel A.

Liver Int. 2013 May;33(5):780-93. doi: 10.1111/liv.12126. Epub 2013 Mar 15.

PMID:
23489999
39.

Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth.

Schmid B, Hruscha A, Hogl S, Banzhaf-Strathmann J, Strecker K, van der Zee J, Teucke M, Eimer S, Hegermann J, Kittelmann M, Kremmer E, Cruts M, Solchenberger B, Hasenkamp L, van Bebber F, Van Broeckhoven C, Edbauer D, Lichtenthaler SF, Haass C.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):4986-91. doi: 10.1073/pnas.1218311110. Epub 2013 Mar 1.

40.

Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro.

Kensah G, Roa Lara A, Dahlmann J, Zweigerdt R, Schwanke K, Hegermann J, Skvorc D, Gawol A, Azizian A, Wagner S, Maier LS, Krause A, Dräger G, Ochs M, Haverich A, Gruh I, Martin U.

Eur Heart J. 2013 Apr;34(15):1134-46. doi: 10.1093/eurheartj/ehs349. Epub 2012 Oct 26.

PMID:
23103664
41.

RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.

Sasidharan N, Sumakovic M, Hannemann M, Hegermann J, Liewald JF, Olendrowitz C, Koenig S, Grant BD, Rizzoli SO, Gottschalk A, Eimer S.

Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18944-9. doi: 10.1073/pnas.1203306109. Epub 2012 Oct 25.

42.

Does augmentation with alpha1-antitrypsin affect neutrophil extracellular traps formation?

Frenzel E, Korenbaum E, Hegermann J, Ochs M, Koepke J, Koczulla AR, Welte T, Köhnlein T, Janciauskiene S.

Int J Biol Sci. 2012;8(7):1023-5. doi: 10.7150/ijbs.4701. Epub 2012 Aug 8. No abstract available.

43.

miRNAs can increase the efficiency of ex vivo platelet generation.

Emmrich S, Henke K, Hegermann J, Ochs M, Reinhardt D, Klusmann JH.

Ann Hematol. 2012 Nov;91(11):1673-84. doi: 10.1007/s00277-012-1517-z. Epub 2012 Jul 5.

PMID:
22763947
44.

TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans.

Hannemann M, Sasidharan N, Hegermann J, Kutscher LM, Koenig S, Eimer S.

PLoS Genet. 2012;8(5):e1002722. doi: 10.1371/journal.pgen.1002722. Epub 2012 May 24.

45.

The endoplasmic reticulum localized PIN8 is a pollen-specific auxin carrier involved in intracellular auxin homeostasis.

Dal Bosco C, Dovzhenko A, Liu X, Woerner N, Rensch T, Eismann M, Eimer S, Hegermann J, Paponov IA, Ruperti B, Heberle-Bors E, Touraev A, Cohen JD, Palme K.

Plant J. 2012 Sep;71(5):860-70. doi: 10.1111/j.1365-313X.2012.05037.x. Epub 2012 Jul 3.

46.

Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.

Alten L, Schuster-Gossler K, Beckers A, Groos S, Ulmer B, Hegermann J, Ochs M, Gossler A.

Development. 2012 Apr;139(7):1276-84. doi: 10.1242/dev.072728. Epub 2012 Feb 22.

47.

The Caenorhabditis elegans GARP complex contains the conserved Vps51 subunit and is required to maintain lysosomal morphology.

Luo L, Hannemann M, Koenig S, Hegermann J, Ailion M, Cho MK, Sasidharan N, Zweckstetter M, Rensing SA, Eimer S.

Mol Biol Cell. 2011 Jul 15;22(14):2564-78. doi: 10.1091/mbc.E10-06-0493. Epub 2011 May 25.

48.

TFG-1 function in protein secretion and oncogenesis.

Witte K, Schuh AL, Hegermann J, Sarkeshik A, Mayers JR, Schwarze K, Yates JR 3rd, Eimer S, Audhya A.

Nat Cell Biol. 2011 May;13(5):550-8. doi: 10.1038/ncb2225. Epub 2011 Apr 10.

49.

Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

Kamp F, Exner N, Lutz AK, Wender N, Hegermann J, Brunner B, Nuscher B, Bartels T, Giese A, Beyer K, Eimer S, Winklhofer KF, Haass C.

EMBO J. 2010 Oct 20;29(20):3571-89. doi: 10.1038/emboj.2010.223. Epub 2010 Sep 14.

50.

UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans.

Sumakovic M, Hegermann J, Luo L, Husson SJ, Schwarze K, Olendrowitz C, Schoofs L, Richmond J, Eimer S.

J Cell Biol. 2009 Sep 21;186(6):897-914. doi: 10.1083/jcb.200902096.

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