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A wide star-black-hole binary system from radial-velocity measurements.

Liu J, Zhang H, Howard AW, Bai Z, Lu Y, Soria R, Justham S, Li X, Zheng Z, Wang T, Belczynski K, Casares J, Zhang W, Yuan H, Dong Y, Lei Y, Isaacson H, Wang S, Bai Y, Shao Y, Gao Q, Wang Y, Niu Z, Cui K, Zheng C, Mu X, Zhang L, Wang W, Heger A, Qi Z, Liao S, Lattanzi M, Gu WM, Wang J, Wu J, Shao L, Shen R, Wang X, Bregman J, Di Stefano R, Liu Q, Han Z, Zhang T, Wang H, Ren J, Zhang J, Zhang J, Wang X, Cabrera-Lavers A, Corradi R, Rebolo R, Zhao Y, Zhao G, Chu Y, Cui X.

Nature. 2019 Nov;575(7784):618-621. doi: 10.1038/s41586-019-1766-2. Epub 2019 Nov 27.


Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling.

Ilott NE, Bollrath J, Danne C, Schiering C, Shale M, Adelmann K, Krausgruber T, Heger A, Sims D, Powrie F.

ISME J. 2020 Mar;14(3):879. doi: 10.1038/s41396-019-0539-0.


Fatal attack on a pedestrian by an escaped circus elephant.

Heger A, Schwarz CS, Krauskopf A, Heinze S.

Forensic Sci Int. 2019 Jul;300:e1-e3. doi: 10.1016/j.forsciint.2019.04.027. Epub 2019 May 1.


Sequencing of human genomes with nanopore technology.

Bowden R, Davies RW, Heger A, Pagnamenta AT, de Cesare M, Oikkonen LE, Parkes D, Freeman C, Dhalla F, Patel SY, Popitsch N, Ip CLC, Roberts HE, Salatino S, Lockstone H, Lunter G, Taylor JC, Buck D, Simpson MA, Donnelly P.

Nat Commun. 2019 Apr 23;10(1):1869. doi: 10.1038/s41467-019-09637-5.


The Light Chain IgLV3-21 Defines a New Poor Prognostic Subgroup in Chronic Lymphocytic Leukemia: Results of a Multicenter Study.

Stamatopoulos B, Smith T, Crompot E, Pieters K, Clifford R, Mraz M, Robbe P, Burns A, Timbs A, Bruce D, Hillmen P, Meuleman N, Mineur P, Firescu R, Maerevoet M, De Wilde V, Efira A, Philippé J, Verhasselt B, Offner F, Sims D, Heger A, Dreau H, Schuh A.

Clin Cancer Res. 2018 Oct 15;24(20):5048-5057. doi: 10.1158/1078-0432.CCR-18-0133. Epub 2018 Jun 26.


Genomic Response to Vitamin D Supplementation in the Setting of a Randomized, Placebo-Controlled Trial.

Berlanga-Taylor AJ, Plant K, Dahl A, Lau E, Hill M, Sims D, Heger A, Emberson J, Armitage J, Clarke R, Knight JC.

EBioMedicine. 2018 May;31:133-142. doi: 10.1016/j.ebiom.2018.04.010. Epub 2018 Apr 10.


Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations.

Cartier J, Smith T, Thomson JP, Rose CM, Khulan B, Heger A, Meehan RR, Drake AJ.

Genome Biol. 2018 Apr 10;19(1):50. doi: 10.1186/s13059-018-1422-4.


Smoking Decreases Endometrial Thickness in IVF/ICSI Patients.

Heger A, Sator M, Walch K, Pietrowski D.

Geburtshilfe Frauenheilkd. 2018 Jan;78(1):78-82. doi: 10.1055/s-0043-123762. Epub 2018 Jan 22.


Motivational (con)fusion: Identity fusion does not quell personal self-interest.

Gaertner L, Heger A, Sedikides C.

Behav Brain Sci. 2018 Jan;41:e202. doi: 10.1017/S0140525X18001607.


Thawing of Pooled, Solvent/Detergent-Treated Plasma octaplasLG®: Validation Studies Using Different Thawing Devices.

Heger A, Pock K, Römisch J.

Transfus Med Hemother. 2017 Apr;44(2):94-98. doi: 10.1159/000460302. Epub 2017 Mar 14.


Familial childhood-onset progressive cerebellar syndrome associated with the ATP1A3 mutation.

Jaffer F, Fawcett K, Sims D, Heger A, Houlden H, Hanna MG, Kingston H, Sisodiya SM.

Neurol Genet. 2017 Mar 27;3(2):e145. doi: 10.1212/NXG.0000000000000145. eCollection 2017 Apr. No abstract available.


UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy.

Smith T, Heger A, Sudbery I.

Genome Res. 2017 Mar;27(3):491-499. doi: 10.1101/gr.209601.116. Epub 2017 Jan 18.


Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson's disease.

Sandor C, Robertson P, Lang C, Heger A, Booth H, Vowles J, Witty L, Bowden R, Hu M, Cowley SA, Wade-Martins R, Webber C.

Hum Mol Genet. 2017 Feb 1;26(3):552-566. doi: 10.1093/hmg/ddw412.


11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet.

Johnson JS, Opiyo MN, Thomson M, Gharbi K, Seckl JR, Heger A, Chapman KE.

J Endocrinol. 2017 Feb;232(2):273-283. Epub 2016 Nov 24.


Evidence from stable isotopes and 10Be for solar system formation triggered by a low-mass supernova.

Banerjee P, Qian YZ, Heger A, Haxton WC.

Nat Commun. 2016 Nov 22;7:13639. doi: 10.1038/ncomms13639.


High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner.

Chambers TJG, Morgan MD, Heger AH, Sharpe RM, Drake AJ.

Sci Rep. 2016 Aug 23;6:31857. doi: 10.1038/srep31857.


New bone post-processing tools in forensic imaging: a multi-reader feasibility study to evaluate detection time and diagnostic accuracy in rib fracture assessment.

Glemser PA, Pfleiderer M, Heger A, Tremper J, Krauskopf A, Schlemmer HP, Yen K, Simons D.

Int J Legal Med. 2017 Mar;131(2):489-496. doi: 10.1007/s00414-016-1412-6. Epub 2016 Jul 22.


Long noncoding RNAs in B-cell development and activation.

Brazão TF, Johnson JS, Müller J, Heger A, Ponting CP, Tybulewicz VL.

Blood. 2016 Aug 18;128(7):e10-9. doi: 10.1182/blood-2015-11-680843. Epub 2016 Jul 5.


Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling.

Ilott NE, Bollrath J, Danne C, Schiering C, Shale M, Adelmann K, Krausgruber T, Heger A, Sims D, Powrie F.

ISME J. 2016 Oct;10(10):2389-404. doi: 10.1038/ismej.2016.40. Epub 2016 Mar 22. Erratum in: ISME J. 2020 Mar;14(3):879.


Five-day stability of thawed plasma: solvent/detergent-treated plasma comparable with fresh-frozen plasma and plasma frozen within 24 hours.

Neisser-Svae A, Trawnicek L, Heger A, Mehta T, Triulzi D.

Transfusion. 2016 Feb;56(2):404-9. doi: 10.1111/trf.13356. Epub 2015 Sep 29.


First Direct Measurement of (12)C((12)C,n)(23)Mg at Stellar Energies.

Bucher B, Tang XD, Fang X, Heger A, Almaraz-Calderon S, Alongi A, Ayangeakaa AD, Beard M, Best A, Browne J, Cahillane C, Couder M, deBoer RJ, Kontos A, Lamm L, Li YJ, Long A, Lu W, Lyons S, Notani M, Patel D, Paul N, Pignatari M, Roberts A, Robertson D, Smith K, Stech E, Talwar R, Tan WP, Wiescher M, Woosley SE.

Phys Rev Lett. 2015 Jun 26;114(25):251102. Epub 2015 Jun 25.


CGAT: a model for immersive personalized training in computational genomics.

Sims D, Ponting CP, Heger A.

Brief Funct Genomics. 2016 Jan;15(1):32-7. doi: 10.1093/bfgp/elv021. Epub 2015 May 16. Review.


Corrigendum: Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes.

Ilott NE, Heward JA, Roux B, Tsitsiou E, Fenwick PS, Lenzi L, Goodhead I, Hertz-Fowler C, Heger A, Hall N, Donnelly LE, Sims D, Lindsay MA.

Nat Commun. 2015 Apr 9;6:6814. doi: 10.1038/ncomms7814. No abstract available.


Identification of a candidate prognostic gene signature by transcriptome analysis of matched pre- and post-treatment prostatic biopsies from patients with advanced prostate cancer.

Rajan P, Stockley J, Sudbery IM, Fleming JT, Hedley A, Kalna G, Sims D, Ponting CP, Heger A, Robson CN, McMenemin RM, Pedley ID, Leung HY.

BMC Cancer. 2014 Dec 18;14:977. doi: 10.1186/1471-2407-14-977.


Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia.

Sansom SN, Shikama-Dorn N, Zhanybekova S, Nusspaumer G, Macaulay IC, Deadman ME, Heger A, Ponting CP, Holländer GA.

Genome Res. 2014 Dec;24(12):1918-31. doi: 10.1101/gr.171645.113. Epub 2014 Sep 15.


IRF5:RelA interaction targets inflammatory genes in macrophages.

Saliba DG, Heger A, Eames HL, Oikonomopoulos S, Teixeira A, Blazek K, Androulidaki A, Wong D, Goh FG, Weiss M, Byrne A, Pasparakis M, Ragoussis J, Udalova IA.

Cell Rep. 2014 Sep 11;8(5):1308-17. doi: 10.1016/j.celrep.2014.07.034. Epub 2014 Aug 21.


Early solar system. Stellar origin of the ¹⁸²Hf cosmochronometer and the presolar history of solar system matter.

Lugaro M, Heger A, Osrin D, Goriely S, Zuber K, Karakas AI, Gibson BK, Doherty CL, Lattanzio JC, Ott U.

Science. 2014 Aug 8;345(6197):650-3. doi: 10.1126/science.1253338.


Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes.

IIott NE, Heward JA, Roux B, Tsitsiou E, Fenwick PS, Lenzi L, Goodhead I, Hertz-Fowler C, Heger A, Hall N, Donnelly LE, Sims D, Lindsay MA.

Nat Commun. 2014 Jun 9;5:3979. doi: 10.1038/ncomms4979. Erratum in: Nat Commun. 2015;6:6814.


Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment.

Cooper S, Dienstbier M, Hassan R, Schermelleh L, Sharif J, Blackledge NP, De Marco V, Elderkin S, Koseki H, Klose R, Heger A, Brockdorff N.

Cell Rep. 2014 Jun 12;7(5):1456-1470. doi: 10.1016/j.celrep.2014.04.012. Epub 2014 May 22.


Effective helium burning rates and the production of the neutrino nuclei.

Austin SM, West C, Heger A.

Phys Rev Lett. 2014 Mar 21;112(11):111101. Epub 2014 Mar 17.


A single low-energy, iron-poor supernova as the source of metals in the star SMSS J031300.36-670839.3.

Keller SC, Bessell MS, Frebel A, Casey AR, Asplund M, Jacobson HR, Lind K, Norris JE, Yong D, Heger A, Magic Z, Da Costa GS, Schmidt BP, Tisserand P.

Nature. 2014 Feb 27;506(7489):463-6. doi: 10.1038/nature12990. Epub 2014 Feb 9.


Sequencing depth and coverage: key considerations in genomic analyses.

Sims D, Sudbery I, Ilott NE, Heger A, Ponting CP.

Nat Rev Genet. 2014 Feb;15(2):121-32. doi: 10.1038/nrg3642. Review.


CGAT: computational genomics analysis toolkit.

Sims D, Ilott NE, Sansom SN, Sudbery IM, Johnson JS, Fawcett KA, Berlanga-Taylor AJ, Luna-Valero S, Ponting CP, Heger A.

Bioinformatics. 2014 May 1;30(9):1290-1. doi: 10.1093/bioinformatics/btt756. Epub 2014 Jan 5.


Neurodevelopmental and esthetic results in children after surgical correction of metopic suture synostosis: a single institutional experience.

Kunz M, Lehner M, Heger A, Armbruster L, Weigand H, Mast G, Peraud A.

Childs Nerv Syst. 2014 Jun;30(6):1075-82. doi: 10.1007/s00381-013-2340-0. Epub 2013 Dec 13.


Pfam: the protein families database.

Finn RD, Bateman A, Clements J, Coggill P, Eberhardt RY, Eddy SR, Heger A, Hetherington K, Holm L, Mistry J, Sonnhammer EL, Tate J, Punta M.

Nucleic Acids Res. 2014 Jan;42(Database issue):D222-30. doi: 10.1093/nar/gkt1223. Epub 2013 Nov 27.


Next-generation sequencing of advanced prostate cancer treated with androgen-deprivation therapy.

Rajan P, Sudbery IM, Villasevil ME, Mui E, Fleming J, Davis M, Ahmad I, Edwards J, Sansom OJ, Sims D, Ponting CP, Heger A, McMenemin RM, Pedley ID, Leung HY.

Eur Urol. 2014 Jul;66(1):32-9. doi: 10.1016/j.eururo.2013.08.011. Epub 2013 Aug 14.


GAT: a simulation framework for testing the association of genomic intervals.

Heger A, Webber C, Goodson M, Ponting CP, Lunter G.

Bioinformatics. 2013 Aug 15;29(16):2046-8. doi: 10.1093/bioinformatics/btt343. Epub 2013 Jun 18.


Universal pooled plasma (Uniplas(®)) does not induce complement-mediated hemolysis of human red blood cells in vitro.

Heger A, Brandstätter H, Prager B, Brainovic J, Cortes R, Römisch J.

Transfus Apher Sci. 2015 Feb;52(1):128-35. doi: 10.1016/j.transci.2013.04.039. Epub 2013 May 23.


New primary mechanisms for the synthesis of rare 9Be in early supernovae.

Banerjee P, Qian YZ, Haxton WC, Heger A.

Phys Rev Lett. 2013 Apr 5;110(14):141101. Epub 2013 Apr 1.


Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates.

Long HK, Sims D, Heger A, Blackledge NP, Kutter C, Wright ML, Grützner F, Odom DT, Patient R, Ponting CP, Klose RJ.

Elife. 2013 Feb 26;2:e00348. doi: 10.7554/eLife.00348.


Insights into the evolution of Darwin's finches from comparative analysis of the Geospiza magnirostris genome sequence.

Rands CM, Darling A, Fujita M, Kong L, Webster MT, Clabaut C, Emes RD, Heger A, Meader S, Hawkins MB, Eisen MB, Teiling C, Affourtit J, Boese B, Grant PR, Grant BR, Eisen JA, Abzhanov A, Ponting CP.

BMC Genomics. 2013 Feb 12;14:95. doi: 10.1186/1471-2164-14-95.


Astrophysics: Going supernova.

Heger A.

Nature. 2013 Feb 7;494(7435):46-7. doi: 10.1038/494046a. No abstract available. Erratum in: Nature. 2013 Feb 21;494(7437):322.


Evidence for conserved post-transcriptional roles of unitary pseudogenes and for frequent bifunctionality of mRNAs.

Marques AC, Tan J, Lee S, Kong L, Heger A, Ponting CP.

Genome Biol. 2012 Nov 15;13(11):R102. doi: 10.1186/gb-2012-13-11-r102.


Intake of a resveratrol-containing dietary supplement has no impact on DNA stability in healthy subjects.

Heger A, Ferk F, Nersesyan A, Szekeres T, Kundi M, Wagner KH, Haidinger G, Mišík M, Knasmüller S.

Mutat Res. 2012 Dec 12;749(1-2):82-6. doi: 10.1016/j.mrgentox.2012.07.005. Epub 2012 Sep 5.


Endometrial Receptivity and its Predictive Value for IVF/ICSI-Outcome.

Heger A, Sator M, Pietrowski D.

Geburtshilfe Frauenheilkd. 2012 Aug;72(8):710-715.


Sexual assault documentation program.

Willoughby V, Heger A, Rogers C, Sathyavagiswaran L.

Am J Forensic Med Pathol. 2012 Mar;33(1):22-5.


Insights into hominid evolution from the gorilla genome sequence.

Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, Herrero J, Hobolth A, Lappalainen T, Mailund T, Marques-Bonet T, McCarthy S, Montgomery SH, Schwalie PC, Tang YA, Ward MC, Xue Y, Yngvadottir B, Alkan C, Andersen LN, Ayub Q, Ball EV, Beal K, Bradley BJ, Chen Y, Clee CM, Fitzgerald S, Graves TA, Gu Y, Heath P, Heger A, Karakoc E, Kolb-Kokocinski A, Laird GK, Lunter G, Meader S, Mort M, Mullikin JC, Munch K, O'Connor TD, Phillips AD, Prado-Martinez J, Rogers AS, Sajjadian S, Schmidt D, Shaw K, Simpson JT, Stenson PD, Turner DJ, Vigilant L, Vilella AJ, Whitener W, Zhu B, Cooper DN, de Jong P, Dermitzakis ET, Eichler EE, Flicek P, Goldman N, Mundy NI, Ning Z, Odom DT, Ponting CP, Quail MA, Ryder OA, Searle SM, Warren WC, Wilson RK, Schierup MH, Rogers J, Tyler-Smith C, Durbin R.

Nature. 2012 Mar 7;483(7388):169-75. doi: 10.1038/nature10842.

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