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Items: 1 to 50 of 76

1.

CPn0572, the C. pneumoniae ortholog of TarP, reorganizes the actin cytoskeleton via a newly identified F-actin binding domain and recruitment of vinculin.

Braun C, Alcázar-Román AR, Laska A, Mölleken K, Fleig U, Hegemann JH.

PLoS One. 2019 Jan 10;14(1):e0210403. doi: 10.1371/journal.pone.0210403. eCollection 2019.

2.

Vaginal Gel Component Hydroxyethyl Cellulose Significantly Enhances the Infectivity of Chlamydia trachomatis Serovars D and E.

Raffai T, Burián K, Janovák L, Bogdanov A, Hegemann JH, Endrész V, Virok DP.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e02034-18. doi: 10.1128/AAC.02034-18. Print 2019 Jan.

3.

The Chlamydia pneumoniae Tarp Ortholog CPn0572 Stabilizes Host F-Actin by Displacement of Cofilin.

Zrieq R, Braun C, Hegemann JH.

Front Cell Infect Microbiol. 2017 Dec 12;7:511. doi: 10.3389/fcimb.2017.00511. eCollection 2017.

4.

Genome sequencing of Chlamydia trachomatis serovars E and F reveals substantial genetic variation.

Eder T, Kobus S, Stallmann S, Stepanow S, Köhrer K, Hegemann JH, Rattei T.

Pathog Dis. 2017 Dec 29;75(9). doi: 10.1093/femspd/ftx120.

5.

Broad recruitment of mGBP family members to Chlamydia trachomatis inclusions.

Lindenberg V, Mölleken K, Kravets E, Stallmann S, Hegemann JH, Degrandi D, Pfeffer K.

PLoS One. 2017 Sep 25;12(9):e0185273. doi: 10.1371/journal.pone.0185273. eCollection 2017.

6.

Acquisition of Rab11 and Rab11-Fip2-A novel strategy for Chlamydia pneumoniae early survival.

Mölleken K, Hegemann JH.

PLoS Pathog. 2017 Aug 7;13(8):e1006556. doi: 10.1371/journal.ppat.1006556. eCollection 2017 Aug.

7.

Vaccination with the polymorphic membrane protein A reduces Chlamydia muridarum induced genital tract pathology.

Müller T, Becker E, Stallmann S, Waldhuber A, Römmler-Dreher F, Albrecht S, Mohr F, Hegemann JH, Miethke T.

Vaccine. 2017 May 15;35(21):2801-2810. doi: 10.1016/j.vaccine.2017.04.017. Epub 2017 Apr 14.

PMID:
28413133
8.

Comparison of the nine polymorphic membrane proteins of Chlamydia trachomatis for their ability to induce protective immune responses in mice against a C. muridarum challenge.

Pal S, Favaroni A, Tifrea DF, Hanisch PT, Luczak SET, Hegemann JH, de la Maza LM.

Vaccine. 2017 May 2;35(19):2543-2549. doi: 10.1016/j.vaccine.2017.03.070. Epub 2017 Apr 3.

9.

A Probiotic Adjuvant Lactobacillus rhamnosus Enhances Specific Immune Responses after Ocular Mucosal Immunization with Chlamydial Polymorphic Membrane Protein C.

Inic-Kanada A, Stojanovic M, Marinkovic E, Becker E, Stein E, Lukic I, Djokic R, Schuerer N, Hegemann JH, Barisani-Asenbauer T.

PLoS One. 2016 Sep 16;11(9):e0157875. doi: 10.1371/journal.pone.0157875. eCollection 2016.

10.

The Chlamydia pneumoniae Adhesin Pmp21 Forms Oligomers with Adhesive Properties.

Luczak SE, Smits SH, Decker C, Nagel-Steger L, Schmitt L, Hegemann JH.

J Biol Chem. 2016 Oct 21;291(43):22806-22818. Epub 2016 Aug 22.

11.

The Type III Secretion System-Related CPn0809 from Chlamydia pneumoniae.

Engel AC, Herbst F, Kerres A, Galle JN, Hegemann JH.

PLoS One. 2016 Feb 19;11(2):e0148509. doi: 10.1371/journal.pone.0148509. eCollection 2016.

12.

The novel chlamydial adhesin CPn0473 mediates the lipid raft-dependent uptake of Chlamydia pneumoniae.

Fechtner T, Galle JN, Hegemann JH.

Cell Microbiol. 2016 Aug;18(8):1094-105. doi: 10.1111/cmi.12569. Epub 2016 Feb 21.

13.

Genome-wide Screen of Pseudomonas aeruginosa in Saccharomyces cerevisiae Identifies New Virulence Factors.

Zrieq R, Sana TG, Vergin S, Garvis S, Volfson I, Bleves S, Voulhoux R, Hegemann JH.

Front Cell Infect Microbiol. 2015 Nov 16;5:81. doi: 10.3389/fcimb.2015.00081. eCollection 2015.

14.

The Chlamydia trachomatis Ctad1 invasin exploits the human integrin β1 receptor for host cell entry.

Stallmann S, Hegemann JH.

Cell Microbiol. 2016 May;18(5):761-75. doi: 10.1111/cmi.12549. Epub 2016 Jan 17.

PMID:
26597572
15.

OmpA family proteins and Pmp-like autotransporter: new adhesins of Waddlia chondrophila.

Kebbi-Beghdadi C, Domröse A, Becker E, Cisse OH, Hegemann JH, Greub G.

Pathog Dis. 2015 Aug;73(6):ftv035. doi: 10.1093/femspd/ftv035. Epub 2015 May 17.

PMID:
25986220
16.

All subtypes of the Pmp adhesin family are implicated in chlamydial virulence and show species-specific function.

Becker E, Hegemann JH.

Microbiologyopen. 2014 Aug;3(4):544-56. doi: 10.1002/mbo3.186. Epub 2014 Jul 1.

17.

Targeted gene deletion in Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Hegemann JH, Heick SB, Pöhlmann J, Langen MM, Fleig U.

Methods Mol Biol. 2014;1163:45-73. doi: 10.1007/978-1-4939-0799-1_5.

PMID:
24841299
18.

Characterization of the interaction between the chlamydial adhesin OmcB and the human host cell.

Fechtner T, Stallmann S, Moelleken K, Meyer KL, Hegemann JH.

J Bacteriol. 2013 Dec;195(23):5323-33. doi: 10.1128/JB.00780-13. Epub 2013 Sep 20.

19.

The Chlamydia pneumoniae invasin protein Pmp21 recruits the EGF receptor for host cell entry.

Mölleken K, Becker E, Hegemann JH.

PLoS Pathog. 2013;9(4):e1003325. doi: 10.1371/journal.ppat.1003325. Epub 2013 Apr 25.

20.

Delete and repeat: a comprehensive toolkit for sequential gene knockout in the budding yeast Saccharomyces cerevisiae.

Hegemann JH, Heick SB.

Methods Mol Biol. 2011;765:189-206. doi: 10.1007/978-1-61779-197-0_12.

PMID:
21815094
21.

Missense variants in hMLH1 identified in patients from the German HNPCC consortium and functional studies.

Hardt K, Heick SB, Betz B, Goecke T, Yazdanparast H, Küppers R, Servan K, Steinke V, Rahner N, Morak M, Holinski-Feder E, Engel C, Möslein G, Schackert HK, von Knebel Doeberitz M, Pox C; Peter Propping; German HNPCC consortium, Hegemann JH, Royer-Pokora B.

Fam Cancer. 2011 Jun;10(2):273-84. doi: 10.1007/s10689-011-9431-4.

PMID:
21404117
22.

Members of the Pmp protein family of Chlamydia pneumoniae mediate adhesion to human cells via short repetitive peptide motifs.

Mölleken K, Schmidt E, Hegemann JH.

Mol Microbiol. 2010 Nov;78(4):1004-17. doi: 10.1111/j.1365-2958.2010.07386.x. Epub 2010 Oct 6.

23.

Transcriptional regulation of ASK/Dbf4 in cutaneous melanoma is dependent on E2F1.

Nambiar S, Mirmohammadsadegh A, Hassan M, Hegemann JH, Hengge UR.

Exp Dermatol. 2008 Dec;17(12):986-91. doi: 10.1111/j.1600-0625.2008.00730.x. Epub 2008 May 21.

PMID:
18503552
24.

Chlamydia pneumoniae GroEL1 protein is cell surface associated and required for infection of HEp-2 cells.

Wuppermann FN, Mölleken K, Julien M, Jantos CA, Hegemann JH.

J Bacteriol. 2008 May;190(10):3757-67. doi: 10.1128/JB.01638-07. Epub 2008 Feb 29.

25.
26.

Identification and functional characterization of ASK/Dbf4, a novel cell survival gene in cutaneous melanoma with prognostic relevance.

Nambiar S, Mirmohammadsadegh A, Hassan M, Mota R, Marini A, Alaoui A, Tannapfel A, Hegemann JH, Hengge UR.

Carcinogenesis. 2007 Dec;28(12):2501-10. Epub 2007 Sep 3.

PMID:
17768177
27.

Mechanisms of Chlamydophila pneumoniae-mediated GM-CSF release in human bronchial epithelial cells.

Krüll M, Bockstaller P, Wuppermann FN, Klucken AC, Mühling J, Schmeck B, Seybold J, Walter C, Maass M, Rosseau S, Hegemann JH, Suttorp N, Hippenstiel S.

Am J Respir Cell Mol Biol. 2006 Mar;34(3):375-82. Epub 2005 Dec 9.

PMID:
16340003
28.

Gene disruption in the budding yeast Saccharomyces cerevisiae.

Hegemann JH, Güldener U, Köhler GJ.

Methods Mol Biol. 2006;313:129-44.

PMID:
16118431
29.

HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae.

Hopfe M, Hegemann JH, Henrich B.

BMC Microbiol. 2005 May 18;5:27.

30.

Characterization of the Saccharomyces cerevisiae Fol1 protein: starvation for C1 carrier induces pseudohyphal growth.

Güldener U, Koehler GJ, Haussmann C, Bacher A, Kricke J, Becher D, Hegemann JH.

Mol Biol Cell. 2004 Aug;15(8):3811-28. Epub 2004 May 28.

31.

Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes.

Bogengruber E, Briza P, Doppler E, Wimmer H, Koller L, Fasiolo F, Senger B, Hegemann JH, Breitenbach M.

FEMS Yeast Res. 2003 Mar;3(1):35-43.

32.

The vesicular transport protein Cgp1p/Vps54p/Tcs3p/Luv1p is required for the integrity of the actin cytoskeleton.

Fiedler TA, Karpova TS, Fleig U, Young ME, Cooper JA, Hegemann JH.

Mol Genet Genomics. 2002 Oct;268(2):190-205. Epub 2002 Sep 20.

PMID:
12395193
33.

Functional profiling of the Saccharomyces cerevisiae genome.

Giaever G, Chu AM, Ni L, Connelly C, Riles L, Véronneau S, Dow S, Lucau-Danila A, Anderson K, André B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Güldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kötter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M.

Nature. 2002 Jul 25;418(6896):387-91.

PMID:
12140549
34.

Gene disruption.

Johnston M, Riles L, Hegemann JH.

Methods Enzymol. 2002;350:290-315. No abstract available.

PMID:
12073319
35.

A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast.

Gueldener U, Heinisch J, Koehler GJ, Voss D, Hegemann JH.

Nucleic Acids Res. 2002 Mar 15;30(6):e23.

36.

Heparan sulfate-like glycosaminoglycan is a cellular receptor for Chlamydia pneumoniae.

Wuppermann FN, Hegemann JH, Jantos CA.

J Infect Dis. 2001 Jul 15;184(2):181-7. Epub 2001 Jun 5.

PMID:
11424015
37.

Molecular analysis of the Saccharomyces cerevisiae YHR076w gene.

Ramos CW, Güldener U, Klein S, Hegemann JH, Gonzalez S, Rodríguez-Medina JR.

IUBMB Life. 2000 Dec;50(6):371-7.

38.

Infection and activation of airway epithelial cells by Chlamydia pneumoniae.

Jahn HU, Krüll M, Wuppermann FN, Klucken AC, Rosseau S, Seybold J, Hegemann JH, Jantos CA, Suttorp N.

J Infect Dis. 2000 Dec;182(6):1678-87. Epub 2000 Oct 18.

PMID:
11069240
39.

Antibody response to the 60-kDa heat-shock protein of Chlamydia pneumoniae in patients with coronary artery disease.

Jantos CA, Krombach C, Wuppermann FN, Gardemann A, Bepler S, Asslan H, Hegemann JH, Haberbosch W.

J Infect Dis. 2000 May;181(5):1700-5. Epub 2000 May 15.

PMID:
10823771
40.

Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach.

Entian KD, Schuster T, Hegemann JH, Becher D, Feldmann H, Güldener U, Götz R, Hansen M, Hollenberg CP, Jansen G, Kramer W, Klein S, Kötter P, Kricke J, Launhardt H, Mannhaupt G, Maierl A, Meyer P, Mewes W, Munder T, Niedenthal RK, Ramezani Rad M, Röhmer A, Römer A, Hinnen A, et al.

Mol Gen Genet. 1999 Dec;262(4-5):683-702.

PMID:
10628851
41.

Systematic analysis of S. cerevisiae chromosome VIII genes.

Niedenthal R, Riles L, Güldener U, Klein S, Johnston M, Hegemann JH.

Yeast. 1999 Dec;15(16):1775-96.

42.

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.

Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G, Hegemann JH, Jones T, Laub M, Liao H, Liebundguth N, Lockhart DJ, Lucau-Danila A, Lussier M, M'Rabet N, Menard P, Mittmann M, Pai C, Rebischung C, Revuelta JL, Riles L, Roberts CJ, Ross-MacDonald P, Scherens B, Snyder M, Sookhai-Mahadeo S, Storms RK, Véronneau S, Voet M, Volckaert G, Ward TR, Wysocki R, Yen GS, Yu K, Zimmermann K, Philippsen P, Johnston M, Davis RW.

Science. 1999 Aug 6;285(5429):901-6.

43.

A fast method to diagnose chromosome and plasmid loss in Saccharomyces cerevisiae strains.

Hegemann JH, Klein S, Heck S, Güldener U, Niedenthal RK, Fleig U.

Yeast. 1999 Jul;15(10B):1009-19.

45.

Signal transduction pathways activated in endothelial cells following infection with Chlamydia pneumoniae.

Krüll M, Klucken AC, Wuppermann FN, Fuhrmann O, Magerl C, Seybold J, Hippenstiel S, Hegemann JH, Jantos CA, Suttorp N.

J Immunol. 1999 Apr 15;162(8):4834-41.

46.

All 16 centromere DNAs from Saccharomyces cerevisiae show DNA curvature.

Bechert T, Heck S, Fleig U, Diekmann S, Hegemann JH.

Nucleic Acids Res. 1999 Mar 15;27(6):1444-9.

47.

Depolarization of the actin cytoskeleton is a specific phenotype in Saccharomyces cerevisiae.

Karpova TS, Moltz SL, Riles LE, Güldener U, Hegemann JH, Veronneau S, Bussey H, Cooper JA.

J Cell Sci. 1998 Sep;111 ( Pt 17):2689-96.

48.

Rapid detection of Chlamydia pneumoniae by PCR-enzyme immunoassay.

Jantos CA, Roggendorf R, Wuppermann FN, Hegemann JH.

J Clin Microbiol. 1998 Jul;36(7):1890-4.

49.
50.

Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the left arm of chromosome XIV from Saccharomyces cerevisiae.

Sen-Gupta M, Güldener U, Beinhauer J, Fiedler T, Hegemann JH.

Yeast. 1997 Jul;13(9):849-60.

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