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Items: 30

1.

Targeting interferon signaling and CTLA-4 enhance the therapeutic efficacy of anti-PD-1 immunotherapy in preclinical model of HPV+ oral cancer.

Dorta-Estremera S, Hegde VL, Slay RB, Sun R, Yanamandra AV, Nicholas C, Nookala S, Sierra G, Curran MA, Sastry KJ.

J Immunother Cancer. 2019 Sep 18;7(1):252. doi: 10.1186/s40425-019-0728-4.

2.

Cannabinoid exposure during pregnancy and its impact on immune function.

Dong C, Chen J, Harrington A, Vinod KY, Hegde ML, Hegde VL.

Cell Mol Life Sci. 2019 Feb;76(4):729-743. doi: 10.1007/s00018-018-2955-0. Epub 2018 Oct 29. Review.

PMID:
30374520
3.

MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target.

Zhang T, Zhou J, Man GCW, Leung KT, Liang B, Xiao B, Ma X, Huang S, Huang H, Hegde VL, Zhong Y, Li Y, Kong GWS, Yiu AKW, Kwong J, Ng PC, Lessey BA, Nagarkatti PS, Nagarkatti M, Wang CC.

Eur J Immunol. 2018 Jun;48(6):1059-1073. doi: 10.1002/eji.201747417. Epub 2018 Mar 13.

4.

Skin prick test analysis reveals cross-sensitization to tomato profilin and grass pollen in nasobronchialallergic patients with history of tomato food allergy.

Hegde VL, Mahesh PA, Venkatesh YP.

Eur Ann Allergy Clin Immunol. 2018 Jan;50(1):10-18. doi: 10.23822/EurAnnACI.1764-1489.27.

5.

Critical Role of Mast Cells and Peroxisome Proliferator-Activated Receptor γ in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo.

Hegde VL, Singh UP, Nagarkatti PS, Nagarkatti M.

J Immunol. 2015 Jun 1;194(11):5211-22. doi: 10.4049/jimmunol.1401844. Epub 2015 Apr 27.

6.

miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses.

Singh UP, Murphy AE, Enos RT, Shamran HA, Singh NP, Guan H, Hegde VL, Fan D, Price RL, Taub DD, Mishra MK, Nagarkatti M, Nagarkatti PS.

Immunology. 2014 Nov;143(3):478-89. doi: 10.1111/imm.12328.

7.

Histone modifications are associated with Δ9-tetrahydrocannabinol-mediated alterations in antigen-specific T cell responses.

Yang X, Hegde VL, Rao R, Zhang J, Nagarkatti PS, Nagarkatti M.

J Biol Chem. 2014 Jul 4;289(27):18707-18. doi: 10.1074/jbc.M113.545210. Epub 2014 May 19.

8.

Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1.

Jackson AR, Hegde VL, Nagarkatti PS, Nagarkatti M.

J Leukoc Biol. 2014 Apr;95(4):609-19. doi: 10.1189/jlb.0613350. Epub 2013 Dec 6.

9.

Identification and characterization of a basic thaumatin-like protein (TLP 2) as an allergen in sapodilla plum (Manilkara zapota).

Hegde VL, Ashok Kumar HG, Sreenath K, Hegde ML, Venkatesh YP.

Mol Nutr Food Res. 2014 Apr;58(4):894-902. doi: 10.1002/mnfr.201300261. Epub 2013 Dec 5.

PMID:
24311523
10.

The severity of experimental autoimmune cystitis can be ameliorated by anti-CXCL10 Ab treatment.

Singh UP, Singh NP, Guan H, Hegde VL, Price RL, Taub DD, Mishra MK, Nagarkatti M, Nagarkatti PS.

PLoS One. 2013 Nov 21;8(11):e79751. doi: 10.1371/journal.pone.0079751. eCollection 2013.

11.

Distinct microRNA expression profile and targeted biological pathways in functional myeloid-derived suppressor cells induced by Δ9-tetrahydrocannabinol in vivo: regulation of CCAAT/enhancer-binding protein α by microRNA-690.

Hegde VL, Tomar S, Jackson A, Rao R, Yang X, Singh UP, Singh NP, Nagarkatti PS, Nagarkatti M.

J Biol Chem. 2013 Dec 27;288(52):36810-26. doi: 10.1074/jbc.M113.503037. Epub 2013 Nov 7.

12.

Characterization and gene cloning of an acidic thaumatin-like protein (TLP 1), an allergen from sapodilla fruit (Manilkara zapota).

Ashok Kumar HG, Hegde VL, Shetty SM, Venkatesh YP.

Allergol Int. 2013 Dec;62(4):447-62. doi: 10.2332/allergolint.12-OA-0522. Epub 2013 Sep 25.

13.

Perinatal exposure to Δ9-tetrahydrocannabinol triggers profound defects in T cell differentiation and function in fetal and postnatal stages of life, including decreased responsiveness to HIV antigens.

Lombard C, Hegde VL, Nagarkatti M, Nagarkatti PS.

J Pharmacol Exp Ther. 2011 Nov;339(2):607-17. doi: 10.1124/jpet.111.181206. Epub 2011 Aug 10.

14.

Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: evidence from an experimental murine model.

Pandey R, Hegde VL, Nagarkatti M, Nagarkatti PS.

J Pharmacol Exp Ther. 2011 Sep;338(3):819-28. doi: 10.1124/jpet.111.182717. Epub 2011 Jun 14.

15.

Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-κB.

Singh NP, Singh UP, Hegde VL, Guan H, Hofseth L, Nagarkatti M, Nagarkatti PS.

Mol Nutr Food Res. 2011 Aug;55(8):1207-18. doi: 10.1002/mnfr.201000576. Epub 2011 Apr 26.

16.

Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiol.

Hegde VL, Nagarkatti PS, Nagarkatti M.

PLoS One. 2011 Apr 1;6(4):e18281. doi: 10.1371/journal.pone.0018281.

17.

Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties.

Hegde VL, Nagarkatti M, Nagarkatti PS.

Eur J Immunol. 2010 Dec;40(12):3358-71. doi: 10.1002/eji.201040667.

18.

Do cannabinoids have a therapeutic role in transplantation?

Nagarkatti M, Rieder SA, Hegde VL, Kanada S, Nagarkatti P.

Trends Pharmacol Sci. 2010 Aug;31(8):345-50. doi: 10.1016/j.tips.2010.05.006. Epub 2010 Jun 28. Review.

19.

Cannabinoids as novel anti-inflammatory drugs.

Nagarkatti P, Pandey R, Rieder SA, Hegde VL, Nagarkatti M.

Future Med Chem. 2009 Oct;1(7):1333-49. doi: 10.4155/fmc.09.93. Review.

20.

Use of cannabinoids as a novel therapeutic modality against autoimmune hepatitis.

Pandey R, Hegde VL, Singh NP, Hofseth L, Singh U, Ray S, Nagarkatti M, Nagarkatti PS.

Vitam Horm. 2009;81:487-504. doi: 10.1016/S0083-6729(09)81019-4. Review.

21.

CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation.

Hegde VL, Singh NP, Nagarkatti PS, Nagarkatti M.

J Leukoc Biol. 2008 Jul;84(1):134-42. doi: 10.1189/jlb.1107752. Epub 2008 Apr 3.

22.

Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells.

Hegde VL, Hegde S, Cravatt BF, Hofseth LJ, Nagarkatti M, Nagarkatti PS.

Mol Pharmacol. 2008 Jul;74(1):20-33. doi: 10.1124/mol.108.047035. Epub 2008 Apr 3.

23.

Anaphylaxis following ingestion of mango fruit.

Hegde VL, Venkatesh YP.

J Investig Allergol Clin Immunol. 2007;17(5):341-4.

26.

Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria.

Jia W, Hegde VL, Singh NP, Sisco D, Grant S, Nagarkatti M, Nagarkatti PS.

Mol Cancer Res. 2006 Aug;4(8):549-62.

28.

Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E-mediated mechanism.

Hegde VL, Venkatesh YP.

Clin Exp Allergy. 2004 Oct;34(10):1602-9.

PMID:
15479277
29.

Bryostatin-1 enhances the maturation and antigen-presenting ability of murine and human dendritic cells.

Do Y, Hegde VL, Nagarkatti PS, Nagarkatti M.

Cancer Res. 2004 Sep 15;64(18):6756-65.

30.

Oral allergy syndrome to sapodilla (Achras zapota).

Hegde VL, Venkatesh YP.

J Allergy Clin Immunol. 2002 Sep;110(3):533-4. No abstract available.

PMID:
12209110

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