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Items: 1 to 50 of 232

1.

Tumor immune microenvironment and genomic evolution in a patient with metastatic triple negative breast cancer and a complete response to atezolizumab.

Molinero L, Li Y, Chang CW, Maund S, Berg M, Harrison J, Fassò M, O'Hear C, Hegde P, Emens LA.

J Immunother Cancer. 2019 Oct 23;7(1):274. doi: 10.1186/s40425-019-0740-8.

2.

Late-differentiated effector neoantigen-specific CD8+ T cells are enriched in peripheral blood of non-small cell lung carcinoma patients responding to atezolizumab treatment.

Fehlings M, Jhunjhunwala S, Kowanetz M, O'Gorman WE, Hegde PS, Sumatoh H, Lee BH, Nardin A, Becht E, Flynn S, Ballinger M, Newell EW, Yadav M.

J Immunother Cancer. 2019 Sep 12;7(1):249. doi: 10.1186/s40425-019-0695-9.

3.

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.

Guerrero EN, Mitra J, Wang H, Rangaswamy S, Hegde PM, Basu P, Rao KS, Hegde ML.

Hum Mol Genet. 2019 Sep 15;28(18):3161-3162. doi: 10.1093/hmg/ddz141. No abstract available.

4.

Chiral Phase Transition Temperature in (2+1)-Flavor QCD.

Ding HT, Hegde P, Kaczmarek O, Karsch F, Lahiri A, Li ST, Mukherjee S, Ohno H, Petreczky P, Schmidt C, Steinbrecher P; HotQCD Collaboration.

Phys Rev Lett. 2019 Aug 9;123(6):062002. doi: 10.1103/PhysRevLett.123.062002.

PMID:
31491166
5.

A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability-High Cases in 67,000 Patient Samples.

Trabucco SE, Gowen K, Maund SL, Sanford E, Fabrizio DA, Hall MJ, Yakirevich E, Gregg JP, Stephens PJ, Frampton GM, Hegde PS, Miller VA, Ross JS, Hartmaier RJ, Huang SA, Sun JX.

J Mol Diagn. 2019 Nov;21(6):1053-1066. doi: 10.1016/j.jmoldx.2019.06.011. Epub 2019 Aug 22.

6.

Safety, Clinical Activity, and Biological Correlates of Response in Patients with Metastatic Melanoma: Results from a Phase I Trial of Atezolizumab.

Hamid O, Molinero L, Bolen CR, Sosman JA, Muñoz-Couselo E, Kluger HM, McDermott DF, Powderly JD, Sarkar I, Ballinger M, Fassò M, O'Hear C, Chen DS, Hegde PS, Hodi FS.

Clin Cancer Res. 2019 Oct 15;25(20):6061-6072. doi: 10.1158/1078-0432.CCR-18-3488. Epub 2019 Jul 29.

PMID:
31358540
7.

Combined Endosonographic Mediastinal Lymph Node Staging in Positron Emission Tomography and Computed Tomography Node-Negative Non-Small-Cell Lung Cancer in High-Risk Patients.

Hegde P, Molina JC, Thivierge-Southidara M, Jain RV, Gowda A, Ferraro P, Liberman M.

Semin Thorac Cardiovasc Surg. 2019 Jul 17. pii: S1043-0679(19)30175-3. doi: 10.1053/j.semtcvs.2019.07.007. [Epub ahead of print]

PMID:
31325576
8.

Paraganglioma of the spermatic cord: A case report and literature review.

Gontarz B, Hegde P, McFadden D.

Int J Surg Case Rep. 2019;60:368-370. doi: 10.1016/j.ijscr.2019.06.047. Epub 2019 Jun 26.

9.

Stearoyl-CoA Desaturase 1 Protects Ovarian Cancer Cells from Ferroptotic Cell Death.

Tesfay L, Paul BT, Konstorum A, Deng Z, Cox AO, Lee J, Furdui CM, Hegde P, Torti FM, Torti SV.

Cancer Res. 2019 Oct 15;79(20):5355-5366. doi: 10.1158/0008-5472.CAN-19-0369. Epub 2019 Jul 3.

PMID:
31270077
10.

Management of iatrogenic dislodgment of a mandibular third molar into the pterygomandibular space.

Shetty V, Hegde P, Jain S.

Gen Dent. 2019 May-Jun;67(3):e1-e4.

PMID:
31199751
12.

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.

Guerrero EN, Mitra J, Wang H, Rangaswamy S, Hegde PM, Basu P, Rao KS, Hegde ML.

Hum Mol Genet. 2019 Aug 1;28(5):2459-2476. doi: 10.1093/hmg/ddz062. Epub 2019 Apr 1. Erratum in: Hum Mol Genet. 2019 Sep 15;28(18):3161-3162.

PMID:
31067307
13.

An L-fucose specific lectin from Aspergillus niger isolated from mycotic keratitis patient and its interaction with human pancreatic adenocarcinoma PANC-1 cells.

Jagadeesh N, Belur S, Hegde P, Kamalanathan AS, Swamy BM, Inamdar SR.

Int J Biol Macromol. 2019 Aug 1;134:487-497. doi: 10.1016/j.ijbiomac.2019.04.192. Epub 2019 Apr 30.

PMID:
31051203
14.

Evaluation of Four Incisions Used For Radical Neck Dissection- A Comparative Study

Roy S, Shetty V, Sherigar V, Hegde P, Prasad R.

Asian Pac J Cancer Prev. 2019 Feb 26;20(2):575-580.

15.

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.

Mitra J, Guerrero EN, Hegde PM, Liachko NF, Wang H, Vasquez V, Gao J, Pandey A, Taylor JP, Kraemer BC, Wu P, Boldogh I, Garruto RM, Mitra S, Rao KS, Hegde ML.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4696-4705. doi: 10.1073/pnas.1818415116. Epub 2019 Feb 15.

16.

Neoadjuvant denosumab: its role and results in operable cases of giant cell tumour of bone.

Puri A, Gulia A, Hegde P, Verma V, Rekhi B.

Bone Joint J. 2019 Feb;101-B(2):170-177. doi: 10.1302/0301-620X.101B2.BJJ-2018-0907.R2.

PMID:
30700112
17.

Seasonal changes in carbonaceous aerosols over a tropical coastal location in response to meteorological processes.

Aswini AR, Hegde P, Nair PR, Aryasree S.

Sci Total Environ. 2019 Mar 15;656:1261-1279. doi: 10.1016/j.scitotenv.2018.11.366. Epub 2018 Nov 26.

PMID:
30625656
18.

22. My arches are short but still 'i can enjoy food like you'- the SDA concept review and criticism.

Hegde P.

J Indian Prosthodont Soc. 2018 Nov;18(Suppl 2):S81. doi: 10.4103/0972-4052.246693. Review. No abstract available.

19.

Indole-2-Carboxamides Are Active against Mycobacterium abscessus in a Mouse Model of Acute Infection.

Pandya AN, Prathipati PK, Hegde P, Li W, Graham KF, Mandal S, Drescher KM, Destache CJ, Ordway D, Jackson M, North EJ.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e02245-18. doi: 10.1128/AAC.02245-18. Print 2019 Mar.

20.

Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology.

Okrah K, Tarighat S, Liu B, Koeppen H, Wagle MC, Cheng G, Sun C, Dey A, Chang MT, Sumiyoshi T, Mounir Z, Cummings C, Hampton G, Amler L, Fridlyand J, Hegde PS, Turley SJ, Lackner MR, Huang SM.

NPJ Precis Oncol. 2018 Nov 15;2:25. doi: 10.1038/s41698-018-0068-8. eCollection 2018.

21.

Comparison of Healthy and Dandruff Scalp Microbiome Reveals the Role of Commensals in Scalp Health.

Saxena R, Mittal P, Clavaud C, Dhakan DB, Hegde P, Veeranagaiah MM, Saha S, Souverain L, Roy N, Breton L, Misra N, Sharma VK.

Front Cell Infect Microbiol. 2018 Oct 4;8:346. doi: 10.3389/fcimb.2018.00346. eCollection 2018.

22.

Purification, characterization and fine sugar specificity of a N-Acetylgalactosamine specific lectin from Adenia hondala.

Sharma M, Hegde P, Hiremath K, Reddy H V, Kamalanathan AS, Swamy BM, Inamdar SR.

Glycoconj J. 2018 Dec;35(6):511-523. doi: 10.1007/s10719-018-9843-6. Epub 2018 Oct 10.

PMID:
30306293
23.
24.

Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver.

Habib A, Chokr D, Wan J, Hegde P, Mabire M, Siebert M, Ribeiro-Parenti L, Le Gall M, Lettéron P, Pilard N, Mansouri A, Brouillet A, Tardelli M, Weiss E, Le Faouder P, Guillou H, Cravatt BF, Moreau R, Trauner M, Lotersztajn S.

Gut. 2018 Oct 9. pii: gutjnl-2018-316137. doi: 10.1136/gutjnl-2018-316137. [Epub ahead of print]

PMID:
30301768
25.

Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).

Kowanetz M, Zou W, Gettinger SN, Koeppen H, Kockx M, Schmid P, Kadel EE 3rd, Wistuba I, Chaft J, Rizvi NA, Spigel DR, Spira A, Hirsch FR, Cohen V, Smith D, Boyd Z, Miley N, Flynn S, Leveque V, Shames DS, Ballinger M, Mocci S, Shankar G, Funke R, Hampton G, Sandler A, Amler L, Mellman I, Chen DS, Hegde PS.

Proc Natl Acad Sci U S A. 2018 Oct 23;115(43):E10119-E10126. doi: 10.1073/pnas.1802166115. Epub 2018 Oct 8.

26.

Publisher Correction: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.

McDermott DF, Huseni MA, Atkins MB, Motzer RJ, Rini BI, Escudier B, Fong L, Joseph RW, Pal SK, Reeves JA, Sznol M, Hainsworth J, Rathmell WK, Stadler WM, Hutson T, Gore ME, Ravaud A, Bracarda S, Suárez C, Danielli R, Gruenwald V, Choueiri TK, Nickles D, Jhunjhunwala S, Piault-Louis E, Thobhani A, Qiu J, Chen DS, Hegde PS, Schiff C, Fine GD, Powles T.

Nat Med. 2018 Dec;24(12):1941. doi: 10.1038/s41591-018-0235-z.

PMID:
30291359
27.

Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis.

Wang H, Guo W, Mitra J, Hegde PM, Vandoorne T, Eckelmann BJ, Mitra S, Tomkinson AE, Van Den Bosch L, Hegde ML.

Nat Commun. 2018 Sep 11;9(1):3683. doi: 10.1038/s41467-018-06111-6.

28.

A Comparative Evaluation of Stress Distribution with Two Attachment Systems of Varying Heights in a Mandibular Implant-Supported Overdenture: A Three-Dimensional Finite Element Analysis.

Khurana N, Rodrigues S, Shenoy S, Saldanha S, Pai U, Shetty T, N S, Mahesh M, Hegde P.

J Prosthodont. 2019 Feb;28(2):e795-e805. doi: 10.1111/jopr.12966. Epub 2018 Sep 6.

PMID:
30191668
29.

Breast Cancer Risk factor awareness and utilization of screening program: A cross-sectional study among women in the Northern Emirates.

Hegde P, Pande J, Adly HH, Shetty P, Jayakumari A.

Gulf J Oncolog. 2018 May;1(27):24-30.

PMID:
30145548
30.

Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab.

Gandara DR, Paul SM, Kowanetz M, Schleifman E, Zou W, Li Y, Rittmeyer A, Fehrenbacher L, Otto G, Malboeuf C, Lieber DS, Lipson D, Silterra J, Amler L, Riehl T, Cummings CA, Hegde PS, Sandler A, Ballinger M, Fabrizio D, Mok T, Shames DS.

Nat Med. 2018 Sep;24(9):1441-1448. doi: 10.1038/s41591-018-0134-3. Epub 2018 Aug 6.

PMID:
30082870
31.

Transesophageal approach to lung, adrenal biopsy and fiducial placement using endoscopic ultrasonography (EUS): An interventional pulmonology experience. Initial experience of the UCSF-FRETOC (fresno tracheobronchial & oesophageal center) study group.

Pais FM, Shah RA, Vempilly JJ, Gullapalli S, Upadhyay D, Peterson M, Liberman M, Hegde P.

Respir Med. 2018 Aug;141:52-55. doi: 10.1016/j.rmed.2018.06.019. Epub 2018 Jun 21.

PMID:
30053972
32.

MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections.

Li W, Yazidi A, Pandya AN, Hegde P, Tong W, Calado Nogueira de Moura V, North EJ, Sygusch J, Jackson M.

Front Microbiol. 2018 Jul 10;9:1547. doi: 10.3389/fmicb.2018.01547. eCollection 2018.

33.

Phase I study of the anti-α5β1 monoclonal antibody MINT1526A with or without bevacizumab in patients with advanced solid tumors.

Weekes CD, Rosen LS, Capasso A, Wong KM, Ye W, Anderson M, McCall B, Fredrickson J, Wakshull E, Eppler S, Shon-Nguyen Q, Desai R, Huseni M, Hegde PS, Pourmohamad T, Rhee I, Bessudo A.

Cancer Chemother Pharmacol. 2018 Aug;82(2):339-351. doi: 10.1007/s00280-018-3622-8. Epub 2018 Jun 15.

PMID:
29905898
34.

Identifying an early treatment window for predicting breast cancer response to neoadjuvant chemotherapy using immunohistopathology and hemoglobin parameters.

Zhu Q, Tannenbaum S, Kurtzman SH, DeFusco P, Ricci A Jr, Vavadi H, Zhou F, Xu C, Merkulov A, Hegde P, Kane M, Wang L, Sabbath K.

Breast Cancer Res. 2018 Jun 14;20(1):56. doi: 10.1186/s13058-018-0975-1.

35.

Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer.

Jarzabek MA, Proctor WR, Vogt J, Desai R, Dicker P, Cain G, Raja R, Brodbeck J, Stevens D, van der Stok EP, Martens JWM, Verhoef C, Hegde PS, Byrne AT, Tarrant JM.

PLoS One. 2018 Jun 7;13(6):e0198099. doi: 10.1371/journal.pone.0198099. eCollection 2018.

36.

Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.

McDermott DF, Huseni MA, Atkins MB, Motzer RJ, Rini BI, Escudier B, Fong L, Joseph RW, Pal SK, Reeves JA, Sznol M, Hainsworth J, Rathmell WK, Stadler WM, Hutson T, Gore ME, Ravaud A, Bracarda S, Suárez C, Danielli R, Gruenwald V, Choueiri TK, Nickles D, Jhunjhunwala S, Piault-Louis E, Thobhani A, Qiu J, Chen DS, Hegde PS, Schiff C, Fine GD, Powles T.

Nat Med. 2018 Jun;24(6):749-757. doi: 10.1038/s41591-018-0053-3. Epub 2018 Jun 4. Erratum in: Nat Med. 2018 Dec;24(12):1941.

37.

Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver.

Hegde P, Weiss E, Paradis V, Wan J, Mabire M, Sukriti S, Rautou PE, Albuquerque M, Picq O, Gupta AC, Ferrere G, Gilgenkrantz H, Kiaf B, Toubal A, Beaudoin L, Lettéron P, Moreau R, Lehuen A, Lotersztajn S.

Nat Commun. 2018 Jun 1;9(1):2146. doi: 10.1038/s41467-018-04450-y.

38.

An unlikely connection: Rare case of colo-urachal fistula, surgical management, and review of the literature.

Soyster M, Ristau BT, Girard ED, Liang Y, Hegde P, Harnisch BA.

Urol Case Rep. 2018 Feb 23;18:9-10. doi: 10.1016/j.eucr.2018.02.015. eCollection 2018 May. No abstract available.

39.

Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress.

Sengupta S, Yang C, Hegde ML, Hegde PM, Mitra J, Pandey A, Dutta A, Datarwala AT, Bhakat KK, Mitra S.

DNA Repair (Amst). 2018 Jun - Jul;66-67:1-10. doi: 10.1016/j.dnarep.2018.04.001. Epub 2018 Apr 17.

40.

Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer.

Blanchette-Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, Claffey KP, Torti FM, Torti SV.

Oncogene. 2018 Jul;37(29):4013-4032. doi: 10.1038/s41388-018-0243-y. Epub 2018 Apr 26.

41.

Efficacy studies of Sclerotium rolfsii lectin on breast cancer using NOD SCID mouse model.

Hegde P, Narasimhappagari J, Swamy BM, Inamdar SR.

Chem Biol Drug Des. 2018 Aug;92(2):1488-1496. doi: 10.1111/cbdd.13314. Epub 2018 May 31.

PMID:
29675931
42.

Evaluation of bioceramics and zirconia-reinforced glass ionomer cement in repair of furcation perforations: An in vitro study.

Lagisetti AK, Hegde P, Hegde MN.

J Conserv Dent. 2018 Mar-Apr;21(2):184-189. doi: 10.4103/JCD.JCD_397_16.

43.

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel EE III, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Şenbabaoğlu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T.

Nature. 2018 Feb 22;554(7693):544-548. doi: 10.1038/nature25501. Epub 2018 Feb 14.

44.

Randomized Phase II Trial of Parsatuzumab (Anti-EGFL7) or Placebo in Combination with Carboplatin, Paclitaxel, and Bevacizumab for First-Line Nonsquamous Non-Small Cell Lung Cancer.

von Pawel J, Spigel DR, Ervin T, Losonczy G, Barlesi F, Juhász E, Anderson M, McCall B, Wakshull E, Hegde P, Ye W, Chen D, Chang I, Rhee I, Reck M.

Oncologist. 2018 Jun;23(6):654-e58. doi: 10.1634/theoncologist.2017-0690. Epub 2018 Feb 7.

45.

Natural Immunomodulators.

Ortuño-Sahagún D, Zänker K, Rawat AKS, Kaveri SV, Hegde P.

J Immunol Res. 2017;2017:7529408. doi: 10.1155/2017/7529408. Epub 2017 Dec 14. No abstract available.

46.

A mitogenic lectin from Rhizoctonia bataticola arrests growth, inhibits metastasis, and induces apoptosis in human colon epithelial cancer cells.

Hegde P, Rajakumar SB, Swamy BM, Inamdar SR.

J Cell Biochem. 2018 Jul;119(7):5632-5645. doi: 10.1002/jcb.26740. Epub 2018 Mar 14.

PMID:
29384227
47.

Combined Endosonography Reduces Time to Diagnose Pulmonary Coccidioidomycosis.

Shah RA, Vempilly JJ, Noor Ul Husnain SM, Hegde P.

J Bronchology Interv Pulmonol. 2018 Apr;25(2):152-155. doi: 10.1097/LBR.0000000000000454.

PMID:
29346251
48.

Development of a PD-L1 Complementary Diagnostic Immunohistochemistry Assay (SP142) for Atezolizumab.

Vennapusa B, Baker B, Kowanetz M, Boone J, Menzl I, Bruey JM, Fine G, Mariathasan S, McCaffery I, Mocci S, Rost S, Smith D, Dennis E, Tang SY, Damadzadeh B, Walker E, Hegde PS, Williams JA, Koeppen H, Boyd Z.

Appl Immunohistochem Mol Morphol. 2019 Feb;27(2):92-100. doi: 10.1097/PAI.0000000000000594.

50.

Tumor Infiltration Depth as a Prognostic Parameter for Nodal Metastasis in Oral Squamous Cell Carcinoma.

Hegde P, Roy S, Shetty T, Prasad BR, Shetty U.

Int J Appl Basic Med Res. 2017 Oct-Dec;7(4):252-257. doi: 10.4103/ijabmr.IJABMR_66_17. Review.

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