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Items: 1 to 50 of 458

1.

Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective.

Derry PJ, Hegde ML, Jackson GR, Kayed R, Tour JM, Kent TA, Tsa AL.

Prog Neurobiol. 2019 Oct 8:101716. doi: 10.1016/j.pneurobio.2019.101716. [Epub ahead of print] Review.

PMID:
31604111
2.

Hexahydropyrrolo[2,3-b]indole Compounds as Potential Therapeutics for Alzheimer's Disease.

Doens D, Valdés-Tresanco ME, Vasquez V, Carreira MB, De La Guardia Y, Stephens DE, Nguyen VD, Nguyen VT, Gu J, Hegde ML, Larionov OV, Valiente PA, Lleonart R, Fernández PL.

ACS Chem Neurosci. 2019 Oct 16;10(10):4250-4263. doi: 10.1021/acschemneuro.9b00297. Epub 2019 Oct 7.

PMID:
31545596
3.

Type 2 diabetes differentially affects the substrate saturation kinetic attributes of erythrocyte hexokinase and phosphofructokinase.

Bhise S, Rao J, Hegde M, Katyare S.

FEBS Lett. 2019 Sep 14. doi: 10.1002/1873-3468.13604. [Epub ahead of print]

PMID:
31520487
4.

Isolated Partial Anomalous Pulmonary Venous Connection: Development of Volume Overload and Elevated Estimated Pulmonary Pressure in Adults.

Hegde M, Manjunath SC, Usha MK.

J Clin Imaging Sci. 2019 Jun 14;9:29. doi: 10.25259/JCIS-8-2019. eCollection 2019.

5.

Nanofibrillar Ionic Polymer Composites Enable High-Modulus Ion-Conducting Membranes.

Fox RJ, Yu D, Hegde M, Kumbhar AS, Madsen LA, Dingemans TJ.

ACS Appl Mater Interfaces. 2019 Sep 30. doi: 10.1021/acsami.9b10921. [Epub ahead of print]

PMID:
31507155
6.

Immunotherapy for pediatric brain tumors: past and present.

Foster JB, Madsen PJ, Hegde M, Ahmed N, Cole KA, Maris JM, Resnick AC, Storm PB, Waanders AJ.

Neuro Oncol. 2019 Oct 9;21(10):1226-1238. doi: 10.1093/neuonc/noz077.

PMID:
31504801
7.

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.

Guerrero EN, Mitra J, Wang H, Rangaswamy S, Hegde PM, Basu P, Rao KS, Hegde ML.

Hum Mol Genet. 2019 Sep 2. pii: ddz062. doi: 10.1093/hmg/ddz141. [Epub ahead of print] No abstract available.

PMID:
31504503
8.

Faceting-Controlled Zeeman Splitting in Plasmonic TiO2 Nanocrystals.

Yin P, Hegde M, Garnet NS, Tan Y, Radovanovic PV.

Nano Lett. 2019 Sep 11;19(9):6695-6702. doi: 10.1021/acs.nanolett.9b03128. Epub 2019 Aug 29.

PMID:
31448925
9.

Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group.

Roberts RD, Lizardo MM, Reed DR, Hingorani P, Glover J, Allen-Rhoades W, Fan T, Khanna C, Sweet-Cordero EA, Cash T, Bishop MW, Hegde M, Sertil AR, Koelsche C, Mirabello L, Malkin D, Sorensen PH, Meltzer PS, Janeway KA, Gorlick R, Crompton BD.

Cancer. 2019 Oct 15;125(20):3514-3525. doi: 10.1002/cncr.32351. Epub 2019 Jul 29. Review.

PMID:
31355930
10.

Oral candidal carriage correlates with CD4+ cell count but not with HIV and highly active antiretroviral therapy status.

Sah P, Patel P, Chandrashekar C, Martena S, Ballal M, Hegde M, Guddattu V, Murdoch C, Sharma M, Radhakrishnan R.

J Investig Clin Dent. 2019 Jul 17:e12438. doi: 10.1111/jicd.12438. [Epub ahead of print]

PMID:
31313889
11.

Protection of wear resistance behaviour of enamel against electron beam irradiation.

Hegde MN, Gatti P, Hegde ND.

BDJ Open. 2019 Jul 11;5:11. doi: 10.1038/s41405-019-0021-0. eCollection 2019.

12.

Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape.

Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA, Wakefield A, Fousek K, Bielamowicz K, Chow KK, Brawley VS, Byrd TT, Krebs S, Gottschalk S, Wels WS, Baker ML, Dotti G, Mamonkin M, Brenner MK, Orange JS, Ahmed N.

J Clin Invest. 2019 Jul 2;129(8):3464. doi: 10.1172/JCI131246. eCollection 2019 Jul 2. No abstract available.

13.

New Mechanisms of DNA Repair Defects in Fused in Sarcoma-Associated Neurodegeneration: Stage Set for DNA Repair-Based Therapeutics?

Wang H, Hegde ML.

J Exp Neurosci. 2019 Jun 10;13:1179069519856358. doi: 10.1177/1179069519856358. eCollection 2019.

15.

Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.

Guerrero EN, Mitra J, Wang H, Rangaswamy S, Hegde PM, Basu P, Rao KS, Hegde ML.

Hum Mol Genet. 2019 Apr 1. pii: ddz062. doi: 10.1093/hmg/ddz062. [Epub ahead of print]

PMID:
31067307
16.

Differential sensitivity of structural, diffusion, and resting-state functional MRI for detecting brain alterations and verbal memory impairment in temporal lobe epilepsy.

Chang YA, Marshall A, Bahrami N, Mathur K, Javadi SS, Reyes A, Hegde M, Shih JJ, Paul BM, Hagler DJ Jr, McDonald CR.

Epilepsia. 2019 May;60(5):935-947. doi: 10.1111/epi.14736. Epub 2019 Apr 25.

PMID:
31020649
17.

Correction of pseudoexon splicing caused by a novel intronic dysferlin mutation.

Dominov JA, Uyan Ö, McKenna-Yasek D, Nallamilli BRR, Kergourlay V, Bartoli M, Levy N, Hudson J, Evangelista T, Lochmuller H, Krahn M, Rufibach L, Hegde M, Brown RH Jr.

Ann Clin Transl Neurol. 2019 Mar 3;6(4):642-654. doi: 10.1002/acn3.738. eCollection 2019 Apr.

18.

Clinical utility of RNA sequencing to resolve unusual GNE myopathy with a novel promoter deletion.

Chakravorty S, Berger K, Arafat D, Nallamilli BRR, Subramanian HP, Joseph S, Anderson ME, Campbell KP, Glass J, Gibson G, Hegde M.

Muscle Nerve. 2019 Jul;60(1):98-103. doi: 10.1002/mus.26486. Epub 2019 Apr 29.

PMID:
30990900
19.

Cognitive phenotypes in temporal lobe epilepsy are associated with distinct patterns of white matter network abnormalities.

Reyes A, Kaestner E, Bahrami N, Balachandra A, Hegde M, Paul BM, Hermann B, McDonald CR.

Neurology. 2019 Apr 23;92(17):e1957-e1968. doi: 10.1212/WNL.0000000000007370. Epub 2019 Mar 27.

PMID:
30918094
20.

Asymmetric confinement for defining outgrowth directionality.

Holloway PM, Hallinan GI, Hegde M, Lane SIR, Deinhardt K, West J.

Lab Chip. 2019 Apr 9;19(8):1484-1489. doi: 10.1039/c9lc00078j.

PMID:
30899932
21.

Saliva as a biomarker for dental caries: A systematic review.

Hegde MN, Attavar SH, Shetty N, Hegde ND, Hegde NN.

J Conserv Dent. 2019 Jan-Feb;22(1):2-6. doi: 10.4103/JCD.JCD_531_18. Review.

22.

Retraction Note: A homing system targets therapeutic T cells to brain cancer.

Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N.

Nature. 2019 Mar;567(7746):132. doi: 10.1038/s41586-019-0967-z.

23.

Double helical conformation and extreme rigidity in a rodlike polyelectrolyte.

Wang Y, He Y, Yu Z, Gao J, Ten Brinck S, Slebodnick C, Fahs GB, Zanelotti CJ, Hegde M, Moore RB, Ensing B, Dingemans TJ, Qiao R, Madsen LA.

Nat Commun. 2019 Feb 18;10(1):801. doi: 10.1038/s41467-019-08756-3.

24.

Anticancer and antimetastatic potential of enterolactone: Clinical, preclinical and mechanistic perspectives.

Mali AV, Padhye SB, Anant S, Hegde MV, Kadam SS.

Eur J Pharmacol. 2019 Jun 5;852:107-124. doi: 10.1016/j.ejphar.2019.02.022. Epub 2019 Feb 14. Review.

PMID:
30771348
25.

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.

Mitra J, Guerrero EN, Hegde PM, Liachko NF, Wang H, Vasquez V, Gao J, Pandey A, Taylor JP, Kraemer BC, Wu P, Boldogh I, Garruto RM, Mitra S, Rao KS, Hegde ML.

Proc Natl Acad Sci U S A. 2019 Feb 15. pii: 201818415. doi: 10.1073/pnas.1818415116. [Epub ahead of print]

26.

Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome.

Berauer JP, Mezina AI, Okou DT, Sabo A, Muzny DM, Gibbs RA, Hegde MR, Chopra P, Cutler DJ, Perlmutter DH, Bull LN, Thompson RJ, Loomes KM, Spinner NB, Rajagopalan R, Guthery SL, Moore B, Yandell M, Harpavat S, Magee JC, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Alonso EM, Rosenthal P, Squires RH, Wang KS, Finegold MJ, Russo P, Sherker AH, Sokol RJ, Karpen SJ; Childhood Liver Disease Research Network (ChiLDReN).

Hepatology. 2019 Sep;70(3):899-910. doi: 10.1002/hep.30515. Epub 2019 Mar 21.

PMID:
30664273
27.

Evidence-Based Consensus and Systematic Review on Reducing the Time to Diagnosis of Duchenne Muscular Dystrophy.

Aartsma-Rus A, Hegde M, Ben-Omran T, Buccella F, Ferlini A, Gallano P, Howell RR, Leturcq F, Martin AS, Potulska-Chromik A, Saute JA, Schmidt WM, Sejersen T, Tuffery-Giraud S, Uyguner ZO, Witcomb LA, Yau S, Nelson SF.

J Pediatr. 2019 Jan;204:305-313.e14. doi: 10.1016/j.jpeds.2018.10.043. No abstract available.

28.

Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities.

Sanson KR, Hanna RE, Hegde M, Donovan KF, Strand C, Sullender ME, Vaimberg EW, Goodale A, Root DE, Piccioni F, Doench JG.

Nat Commun. 2018 Dec 21;9(1):5416. doi: 10.1038/s41467-018-07901-8.

29.

Genetic landscape and novel disease mechanisms from a large LGMD cohort of 4656 patients.

Nallamilli BRR, Chakravorty S, Kesari A, Tanner A, Ankala A, Schneider T, da Silva C, Beadling R, Alexander JJ, Askree SH, Whitt Z, Bean L, Collins C, Khadilkar S, Gaitonde P, Dastur R, Wicklund M, Mozaffar T, Harms M, Rufibach L, Mittal P, Hegde M.

Ann Clin Transl Neurol. 2018 Dec 1;5(12):1574-1587. doi: 10.1002/acn3.649. eCollection 2018 Dec.

30.
31.

Beyond depression: The impact of executive functioning on quality of life in patients with temporal lobe epilepsy.

Ehrlich T, Reyes A, Paul BM, Uttarwar V, Hartman S, Mathur K, Chang YA, Hegde M, Shih JJ, McDonald CR.

Epilepsy Res. 2019 Jan;149:30-36. doi: 10.1016/j.eplepsyres.2018.11.004. Epub 2018 Nov 13.

PMID:
30468945
32.

Reverse rotary instrumentation in the apical third of the root canal system: An scanning electron microscope analysis.

Bhat R, Hegde MN.

Indian J Dent Res. 2018 Sep-Oct;29(5):594-599. doi: 10.4103/ijdr.IJDR_143_15.

33.

Cannabinoid exposure during pregnancy and its impact on immune function.

Dong C, Chen J, Harrington A, Vinod KY, Hegde ML, Hegde VL.

Cell Mol Life Sci. 2019 Feb;76(4):729-743. doi: 10.1007/s00018-018-2955-0. Epub 2018 Oct 29. Review.

PMID:
30374520
34.

Controlling the Mechanism of Excitonic Splitting in In2O3 Nanocrystals by Carrier Delocalization.

Yin P, Hegde M, Tan Y, Chen S, Garnet N, Radovanovic PV.

ACS Nano. 2018 Nov 27;12(11):11211-11218. doi: 10.1021/acsnano.8b05782. Epub 2018 Oct 18.

PMID:
30335948
35.

An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson's Disease1.

Vasquez V, Mitra J, Perry G, Rao KS, Hegde ML.

J Alzheimers Dis. 2018;66(2):453-460. doi: 10.3233/JAD-180610.

36.

ClinGen Variant Curation Expert Panel experiences and standardized processes for disease and gene-level specification of the ACMG/AMP guidelines for sequence variant interpretation.

Rivera-Muñoz EA, Milko LV, Harrison SM, Azzariti DR, Kurtz CL, Lee K, Mester JL, Weaver MA, Currey E, Craigen W, Eng C, Funke B, Hegde M, Hershberger RE, Mao R, Steiner RD, Vincent LM, Martin CL, Plon SE, Ramos E, Rehm HL, Watson M, Berg JS.

Hum Mutat. 2018 Nov;39(11):1614-1622. doi: 10.1002/humu.23645.

PMID:
30311389
37.

Gene-specific criteria for PTEN variant curation: Recommendations from the ClinGen PTEN Expert Panel.

Mester JL, Ghosh R, Pesaran T, Huether R, Karam R, Hruska KS, Costa HA, Lachlan K, Ngeow J, Barnholtz-Sloan J, Sesock K, Hernandez F, Zhang L, Milko L, Plon SE, Hegde M, Eng C.

Hum Mutat. 2018 Nov;39(11):1581-1592. doi: 10.1002/humu.23636.

PMID:
30311380
38.

Sinomenine hydrochloride sensitizes cervical cancer cells to ionizing radiation by impairing DNA damage response.

Zhang D, Dong Y, Zhao Y, Zhou C, Qian Y, Hegde ML, Wang H, Han S.

Oncol Rep. 2018 Nov;40(5):2886-2895. doi: 10.3892/or.2018.6693. Epub 2018 Sep 10.

PMID:
30226618
39.

Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis.

Wang H, Guo W, Mitra J, Hegde PM, Vandoorne T, Eckelmann BJ, Mitra S, Tomkinson AE, Van Den Bosch L, Hegde ML.

Nat Commun. 2018 Sep 11;9(1):3683. doi: 10.1038/s41467-018-06111-6.

40.

A homing system targets therapeutic T cells to brain cancer.

Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N.

Nature. 2018 Sep;561(7723):331-337. doi: 10.1038/s41586-018-0499-y. Epub 2018 Sep 5. Retraction in: Nature. 2019 Mar;567(7746):132.

41.

CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.

Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH.

Cell. 2018 Aug 23;174(5):1325. doi: 10.1016/j.cell.2018.08.014. No abstract available.

42.

Serial integration of Dean-structured sample cores with linear inertial focussing for enhanced particle and cell sorting.

Holloway PM, Butement J, Hegde M, West J.

Biomicrofluidics. 2018 Jul 9;12(4):044104. doi: 10.1063/1.5038965. eCollection 2018 Jul.

43.

In Vitro Studies of the Antimicrobial and Free-Radical Scavenging Potentials of Silver Nanoparticles Biosynthesized From the Extract of Desmostachya bipinnata.

Guntur SR, Kumar NS, Hegde MM, Dirisala VR.

Anal Chem Insights. 2018 Jul 2;13:1177390118782877. doi: 10.1177/1177390118782877. eCollection 2018.

44.

CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia.

Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH.

Cell. 2018 Jun 28;174(1):172-186.e21. doi: 10.1016/j.cell.2018.05.048. Erratum in: Cell. 2018 Aug 23;174(5):1325.

45.
46.

Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs.

Okonkwo A, Mitra J, Johnson GS, Li L, Dashwood WM, Hegde ML, Yue C, Dashwood RH, Rajendran P.

Mol Nutr Food Res. 2018 Sep;62(18):e1800228. doi: 10.1002/mnfr.201800228. Epub 2018 Jul 19.

47.

Validation of the diagnostic potential of mtDNA copy number derived from whole genome sequencing.

Brockhage R, Slone J, Ma Z, Hegde MR, Valencia CA, Huang T.

J Genet Genomics. 2018 Jun 6. pii: S1673-8527(18)30098-5. doi: 10.1016/j.jgg.2018.06.001. [Epub ahead of print] No abstract available.

PMID:
29910094
48.

Cytotoxicity Evaluation of Combination Irrigant Regimens with MTAD on Two Different Cell Lines.

Ravinanthanan M, Hegde MN, Shetty V, Kumari S.

Contemp Clin Dent. 2018 Apr-Jun;9(2):255-259. doi: 10.4103/ccd.ccd_854_17.

49.

Evaluation of salivary parameters and dental status in adult hemodialysis patients in an indian population.

Shetty P, Hegde MN, Eraly SM.

J Clin Exp Dent. 2018 May 1;10(5):e419-e424. doi: 10.4317/jced.54633. eCollection 2018 May.

50.

Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens.

Hegde M, Strand C, Hanna RE, Doench JG.

PLoS One. 2018 May 25;13(5):e0197547. doi: 10.1371/journal.pone.0197547. eCollection 2018.

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