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Items: 9


Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells.

Heemskerk I, Burt K, Miller M, Chhabra S, Guerra MC, Liu L, Warmflash A.

Elife. 2019 Mar 4;8. pii: e40526. doi: 10.7554/eLife.40526.


Active Tension Network model suggests an exotic mechanical state realized in epithelial tissues.

Noll N, Mani M, Heemskerk I, Streichan SJ, Shraiman BI.

Nat Phys. 2017 Dec;13(12):1221-1226. doi: 10.1038/nphys4219. Epub 2017 Aug 7.


Opening the black box: Stem cell-based modeling of human post-implantation development.

Taniguchi K, Heemskerk I, Gumucio DL.

J Cell Biol. 2019 Feb 4;218(2):410-421. doi: 10.1083/jcb.201810084. Epub 2018 Dec 14. Review.


A synthetic planar cell polarity system reveals localized feedback on Fat4-Ds1 complexes.

Loza O, Heemskerk I, Gordon-Bar N, Amir-Zilberstein L, Jung Y, Sprinzak D.

Elife. 2017 Aug 18;6. pii: e24820. doi: 10.7554/eLife.24820.


Morphogen and community effects determine cell fates in response to BMP4 signaling in human embryonic stem cells.

Nemashkalo A, Ruzo A, Heemskerk I, Warmflash A.

Development. 2017 Sep 1;144(17):3042-3053. doi: 10.1242/dev.153239. Epub 2017 Jul 31.


Differential growth triggers mechanical feedback that elevates Hippo signaling.

Pan Y, Heemskerk I, Ibar C, Shraiman BI, Irvine KD.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):E6974-E6983. doi: 10.1073/pnas.1615012113. Epub 2016 Oct 26.


Pluripotent stem cells as a model for embryonic patterning: From signaling dynamics to spatial organization in a dish.

Heemskerk I, Warmflash A.

Dev Dyn. 2016 Oct;245(10):976-90. doi: 10.1002/dvdy.24432. Epub 2016 Aug 25. Review.


Tissue cartography: compressing bio-image data by dimensional reduction.

Heemskerk I, Streichan SJ.

Nat Methods. 2015 Dec;12(12):1139-42. doi: 10.1038/nmeth.3648. Epub 2015 Nov 2.


Dynamic clonal analysis based on chronic in vivo imaging allows multiscale quantification of growth in the Drosophila wing disc.

Heemskerk I, Lecuit T, LeGoff L.

Development. 2014 Jun;141(11):2339-48. doi: 10.1242/dev.109264.

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