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Items: 41

1.

Functional Studies on Steroid Receptors.

Schlanger S, Heemers HV.

Methods Mol Biol. 2018;1786:117-130. doi: 10.1007/978-1-4939-7845-8_7.

PMID:
29786790
2.

Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.

Luo J, Attard G, Balk SP, Bevan C, Burnstein K, Cato L, Cherkasov A, De Bono JS, Dong Y, Gao AC, Gleave M, Heemers H, Kanayama M, Kittler R, Lang JM, Lee RJ, Logothetis CJ, Matusik R, Plymate S, Sawyers CL, Selth LA, Soule H, Tilley W, Weigel NL, Zoubeidi A, Dehm SM, Raj GV.

Eur Urol. 2018 May;73(5):715-723. doi: 10.1016/j.eururo.2017.11.038. Epub 2017 Dec 16.

PMID:
29258679
3.

Correction: A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer.

Liu S, Kumari S, Hu Q, Senapati D, Venkadakrishnan VB, Wang D, DePriest AD, Schlanger SE, Ben-Salem S, Valenzuela MM, Willard B, Mudambi S, Swetzig WM, Das GM, Shourideh M, Koochekpour S, Falzarano SM, Magi-Galluzzi C, Yadav N, Chen X, Lao C, Wang J, Billaud JN, Heemers HV.

Elife. 2017 Nov 22;6. pii: e33738. doi: 10.7554/eLife.33738. No abstract available.

4.

A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer.

Liu S, Kumari S, Hu Q, Senapati D, Venkadakrishnan VB, Wang D, DePriest AD, Schlanger SE, Ben-Salem S, Valenzuela MM, Willard B, Mudambi S, Swetzig WM, Das GM, Shourideh M, Koochekpour S, Falzarano SM, Magi-Galluzzi C, Yadav N, Chen X, Lao C, Wang J, Billaud JN, Heemers HV.

Elife. 2017 Aug 18;6. pii: e28482. doi: 10.7554/eLife.28482. Erratum in: Elife. 2017 Nov 22;6:.

5.

Rationale for the development of alternative forms of androgen deprivation therapy.

Kumari S, Senapati D, Heemers HV.

Endocr Relat Cancer. 2017 Aug;24(8):R275-R295. doi: 10.1530/ERC-17-0121. Epub 2017 May 31. Review.

6.

Lipid degradation promotes prostate cancer cell survival.

Itkonen HM, Brown M, Urbanucci A, Tredwell G, Ho Lau C, Barfeld S, Hart C, Guldvik IJ, Takhar M, Heemers HV, Erho N, Bloch K, Davicioni E, Derua R, Waelkens E, Mohler JL, Clarke N, Swinnen JV, Keun HC, Rekvig OP, Mills IG.

Oncotarget. 2017 Jun 13;8(24):38264-38275. doi: 10.18632/oncotarget.16123.

7.

Androgen Signaling in Prostate Cancer.

Dai C, Heemers H, Sharifi N.

Cold Spring Harb Perspect Med. 2017 Sep 1;7(9). pii: a030452. doi: 10.1101/cshperspect.a030452. Review.

PMID:
28389515
8.

GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models.

Shourideh M, Azabdaftari G, Attwood K, DePriest A, Wadosky KM, Gillard BM, Karasik E, Heemers H, Kyprianou N, Gelman IH, Corey E, Vessella RL, Mohler JL, Koochekpour S.

Clin Cancer Res. 2016 Jul 25. pii: clincanres.0137.2016. doi: 10.1158/1078-0432.CCR-16-0137. [Epub ahead of print] Retraction in: Clin Cancer Res. 2017 Jul 15;23 (14 ):3973.

PMID:
27458247
9.

Intratumoral and Intertumoral Genomic Heterogeneity of Multifocal Localized Prostate Cancer Impacts Molecular Classifications and Genomic Prognosticators.

Wei L, Wang J, Lampert E, Schlanger S, DePriest AD, Hu Q, Gomez EC, Murakam M, Glenn ST, Conroy J, Morrison C, Azabdaftari G, Mohler JL, Liu S, Heemers HV.

Eur Urol. 2017 Feb;71(2):183-192. doi: 10.1016/j.eururo.2016.07.008. Epub 2016 Jul 21.

10.

Regulators of Androgen Action Resource: a one-stop shop for the comprehensive study of androgen receptor action.

DePriest AD, Fiandalo MV, Schlanger S, Heemers F, Mohler JL, Liu S, Heemers HV.

Database (Oxford). 2016 Feb 13;2016. pii: bav125. doi: 10.1093/database/bav125. Print 2016.

11.

Revisiting nomenclature for the description of prostate cancer androgen-responsiveness.

Heemers HV, Mohler JL.

Am J Clin Exp Urol. 2014 Jul 12;2(2):121-6. eCollection 2014. Review.

12.

Words of wisdom. Re: Activity of cabazitaxel in castration-resistant prostate cancer progressing after docetaxel and next-generation endocrine agents.

Heemers HV, Mohler JL.

Eur Urol. 2014 Sep;66(3):597. doi: 10.1016/j.eururo.2014.06.032. No abstract available.

13.

Targeting androgen receptor action for prostate cancer treatment: does the post-receptor level provide novel opportunities?

Heemers HV.

Int J Biol Sci. 2014 Jun 1;10(6):576-87. doi: 10.7150/ijbs.8479. eCollection 2014. Review.

14.
15.

Androgen-responsive serum response factor target genes regulate prostate cancer cell migration.

Verone AR, Duncan K, Godoy A, Yadav N, Bakin A, Koochekpour S, Jin JP, Heemers HV.

Carcinogenesis. 2013 Aug;34(8):1737-46. doi: 10.1093/carcin/bgt126. Epub 2013 Apr 10.

16.

Androgen receptor and prostate cancer: new insights in an old target translate into novel therapeutic strategies.

Heemers HV.

Curr Drug Targets. 2013 Apr;14(4):399-400. No abstract available.

PMID:
23565752
18.

The association between calcium channel blocker use and prostate cancer outcome.

Poch MA, Mehedint D, Green DJ, Payne-Ondracek R, Fontham ET, Bensen JT, Attwood K, Wilding GE, Guru KA, Underwood W, Mohler JL, Heemers HV.

Prostate. 2013 Jun;73(8):865-72. doi: 10.1002/pros.22632. Epub 2012 Dec 31.

19.

RhoA as a mediator of clinically relevant androgen action in prostate cancer cells.

Schmidt LJ, Duncan K, Yadav N, Regan KM, Verone AR, Lohse CM, Pop EA, Attwood K, Wilding G, Mohler JL, Sebo TJ, Tindall DJ, Heemers HV.

Mol Endocrinol. 2012 May;26(5):716-35. doi: 10.1210/me.2011-1130. Epub 2012 Mar 28.

20.

Androgen action in the prostate gland.

Yadav N, Heemers HV.

Minerva Urol Nefrol. 2012 Mar;64(1):35-49. Review.

PMID:
22402316
21.

Identification of a clinically relevant androgen-dependent gene signature in prostate cancer.

Heemers HV, Schmidt LJ, Sun Z, Regan KM, Anderson SK, Duncan K, Wang D, Liu S, Ballman KV, Tindall DJ.

Cancer Res. 2011 Mar 1;71(5):1978-88. doi: 10.1158/0008-5472.CAN-10-2512. Epub 2011 Feb 15.

22.

Differential regulation of steroid nuclear receptor coregulator expression between normal and neoplastic prostate epithelial cells.

Heemers HV, Schmidt LJ, Kidd E, Raclaw KA, Regan KM, Tindall DJ.

Prostate. 2010 Jun 15;70(9):959-70. doi: 10.1002/pros.21130.

23.

Unraveling the complexities of androgen receptor signaling in prostate cancer cells.

Heemers HV, Tindall DJ.

Cancer Cell. 2009 Apr 7;15(4):245-7. doi: 10.1016/j.ccr.2009.03.009.

24.

Androgen modulation of coregulator expression in prostate cancer cells.

Heemers HV, Regan KM, Schmidt LJ, Anderson SK, Ballman KV, Tindall DJ.

Mol Endocrinol. 2009 Apr;23(4):572-83. doi: 10.1210/me.2008-0363. Epub 2009 Jan 22.

25.

Expression and significance of androgen receptor coactivators in urothelial carcinoma of the bladder.

Boorjian SA, Heemers HV, Frank I, Farmer SA, Schmidt LJ, Sebo TJ, Tindall DJ.

Endocr Relat Cancer. 2009 Mar;16(1):123-37. doi: 10.1677/ERC-08-0124. Epub 2008 Oct 9.

26.

Induction of FLIP expression by androgens protects prostate cancer cells from TRAIL-mediated apoptosis.

Raclaw KA, Heemers HV, Kidd EM, Dehm SM, Tindall DJ.

Prostate. 2008 Nov 1;68(15):1696-706. doi: 10.1002/pros.20844.

27.

Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance.

Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ.

Cancer Res. 2008 Jul 1;68(13):5469-77. doi: 10.1158/0008-5472.CAN-08-0594.

28.

The role of the transcriptional coactivator p300 in prostate cancer progression.

Heemers HV, Debes JD, Tindall DJ.

Adv Exp Med Biol. 2008;617:535-40. doi: 10.1007/978-0-387-69080-3_54.

30.

Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex.

Heemers HV, Tindall DJ.

Endocr Rev. 2007 Dec;28(7):778-808. Epub 2007 Oct 16. Review.

PMID:
17940184
31.

Androgen deprivation increases p300 expression in prostate cancer cells.

Heemers HV, Sebo TJ, Debes JD, Regan KM, Raclaw KA, Murphy LM, Hobisch A, Culig Z, Tindall DJ.

Cancer Res. 2007 Apr 1;67(7):3422-30.

32.

Androgen activation of the sterol regulatory element-binding protein pathway: Current insights.

Heemers HV, Verhoeven G, Swinnen JV.

Mol Endocrinol. 2006 Oct;20(10):2265-77. Epub 2006 Feb 2. Review.

PMID:
16455816
33.

p300 modulates nuclear morphology in prostate cancer.

Debes JD, Sebo TJ, Heemers HV, Kipp BR, Haugen DL, Lohse CM, Tindall DJ.

Cancer Res. 2005 Feb 1;65(3):708-12.

34.

Androgens, lipogenesis and prostate cancer.

Swinnen JV, Heemers H, van de Sande T, de Schrijver E, Brusselmans K, Heyns W, Verhoeven G.

J Steroid Biochem Mol Biol. 2004 Nov;92(4):273-9. Epub 2004 Dec 19. Review.

PMID:
15663990
35.

Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor.

Heemers H, Verrijdt G, Organe S, Claessens F, Heyns W, Verhoeven G, Swinnen JV.

J Biol Chem. 2004 Jul 16;279(29):30880-7. Epub 2004 May 6.

36.

Androgens stimulate coordinated lipogenic gene expression in normal target tissues in vivo.

Heemers H, Vanderhoydonc F, Roskams T, Shechter I, Heyns W, Verhoeven G, Swinnen JV.

Mol Cell Endocrinol. 2003 Jul 31;205(1-2):21-31.

PMID:
12890564
37.

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

Swinnen JV, Van Veldhoven PP, Timmermans L, De Schrijver E, Brusselmans K, Vanderhoydonc F, Van de Sande T, Heemers H, Heyns W, Verhoeven G.

Biochem Biophys Res Commun. 2003 Mar 21;302(4):898-903.

PMID:
12646257
38.

Androgen regulation of lipogenesis.

Swinnen JV, Heemers H, Heyns W, Verhoeven G.

Adv Exp Med Biol. 2002;506(Pt A):379-87. Review. No abstract available.

PMID:
12613937
40.

Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway.

Swinnen JV, Heemers H, Deboel L, Foufelle F, Heyns W, Verhoeven G.

Oncogene. 2000 Oct 26;19(45):5173-81.

41.

Progestins and androgens increase expression of Spot 14 in T47-D breast tumor cells.

Heemers H, Vanderhoydonc F, Heyns W, Verhoeven G, Swinnen JV.

Biochem Biophys Res Commun. 2000 Mar 5;269(1):209-12.

PMID:
10694501

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