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Items: 1 to 50 of 216

1.

Identification of the Antigen Content of Electroimmunoprecipitates.

Beyer NH, Heegaard NHH.

Methods Mol Biol. 2019;2024:119-135. doi: 10.1007/978-1-4939-9597-4_7.

PMID:
31364046
2.

Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma.

Jensen CS, Bahl JM, Østergaard LB, Høgh P, Wermuth L, Heslegrave A, Zetterberg H, Heegaard NHH, Hasselbalch SG, Simonsen AH.

Exp Gerontol. 2019 Jul 1;121:91-98. doi: 10.1016/j.exger.2019.04.003. Epub 2019 Apr 11.

3.

The biomarker potential of cell-free microRNA from cerebrospinal fluid in Parkinsonian Syndromes.

Starhof C, Hejl AM, Heegaard NHH, Carlsen AL, Burton M, Lilje B, Winge K.

Mov Disord. 2019 Feb;34(2):246-254. doi: 10.1002/mds.27542. Epub 2018 Dec 17.

PMID:
30557454
4.

Nationwide prevalence and incidence study of neuromyelitis optica spectrum disorder in Denmark.

Papp V, Illes Z, Magyari M, Koch-Henriksen N, Kant M, Pfleger CC, Roemer SF, Jensen MB, Petersen AE, Nielsen HH, Rosendahl L, Mezei Z, Christensen T, Svendsen K, Hyldgaard Jensen PE, Lydolph MC, Heegaard N, Frederiksen JL, Sellebjerg F, Stenager E, Petersen T.

Neurology. 2018 Dec 11;91(24):e2265-e2275. doi: 10.1212/WNL.0000000000006645. Epub 2018 Nov 9.

5.

Cerebrospinal fluid pro-inflammatory cytokines differentiate parkinsonian syndromes.

Starhof C, Winge K, Heegaard NHH, Skogstrand K, Friis S, Hejl A.

J Neuroinflammation. 2018 Nov 3;15(1):305. doi: 10.1186/s12974-018-1339-6.

6.

Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis.

Sode J, Bank S, Vogel U, Andersen PS, Sørensen SB, Bojesen AB, Andersen MR, Brandslund I, Dessau RB, Hoffmann HJ, Glintborg B, Hetland ML, Locht H, Heegaard NH, Andersen V.

BMC Med Genet. 2018 Sep 12;19(1):165. doi: 10.1186/s12881-018-0680-z.

7.

Value of anti-plasminogen binding peptide, anti-carbonic anhydrase II, immunoglobulin G4, and other serological markers for the differentiation of autoimmune pancreatitis and pancreatic cancer.

Detlefsen S, de Vos JD, Tanassi JT, Heegaard NHH, Fristrup C, Schaffalitzky de Muckadell OB.

Medicine (Baltimore). 2018 Aug;97(31):e11641. doi: 10.1097/MD.0000000000011641.

8.

Quantification of microRNA levels in plasma - Impact of preanalytical and analytical conditions.

Binderup HG, Madsen JS, Heegaard NHH, Houlind K, Andersen RF, Brasen CL.

PLoS One. 2018 Jul 19;13(7):e0201069. doi: 10.1371/journal.pone.0201069. eCollection 2018.

9.

Associations of circulating cell-free microRNA with vasculopathy and vascular events in systemic lupus erythematosus patients.

Kay SD, Carlsen AL, Voss A, Burton M, Diederichsen A, Poulsen MK, Heegaard N.

Scand J Rheumatol. 2019 Jan;48(1):32-41. doi: 10.1080/03009742.2018.1450892. Epub 2018 Jul 9.

PMID:
29985728
10.

Circulating microRNAs disclose biology of normal cognitive function in healthy elderly people - a discovery twin study.

Mengel-From J, Feddersen S, Halekoh U, Heegaard NHH, McGue M, Christensen K, Tan Q, Christiansen L.

Eur J Hum Genet. 2018 Sep;26(9):1378-1387. doi: 10.1038/s41431-018-0157-8. Epub 2018 May 2.

11.

Pediatric Inflammatory Bowel Diseases: Should We Be Looking for Kidney Abnormalities?

Lauritzen D, Andreassen BU, Heegaard NHH, Klinge LG, Walsted AM, Neland M, Nielsen RG, Wittenhagen P.

Inflamm Bowel Dis. 2018 Nov 29;24(12):2599-2605. doi: 10.1093/ibd/izy166.

PMID:
29718370
12.

Circulating, Cell-Free Micro-RNA Profiles Reflect Discordant Development of Dementia in Monozygotic Twins.

Mengel-From J, Rønne ME, Carlsen AL, Skogstrand K, Larsen LA, Tan Q, Christiansen L, Christensen K, Heegaard NHH.

J Alzheimers Dis. 2018;63(2):591-601. doi: 10.3233/JAD-171163.

13.

Concentration of filaggrin monomers, its metabolites and corneocyte surface texture in individuals with a history of atopic dermatitis and controls.

Engebretsen KA, Bandier J, Kezic S, Riethmüller C, Heegaard NHH, Carlsen BC, Linneberg A, Johansen JD, Thyssen JP.

J Eur Acad Dermatol Venereol. 2018 May;32(5):796-804. doi: 10.1111/jdv.14801. Epub 2018 Feb 12.

PMID:
29360238
14.

Plasma MicroRNA Profiles in Patients with Early Rheumatoid Arthritis Responding to Adalimumab plus Methotrexate vs Methotrexate Alone: A Placebo-controlled Clinical Trial.

Sode J, Krintel SB, Carlsen AL, Hetland ML, Johansen JS, Hørslev-Petersen K, Stengaard-Pedersen K, Ellingsen T, Burton M, Junker P, Østergaard M, Heegaard NHH.

J Rheumatol. 2018 Jan;45(1):53-61. doi: 10.3899/jrheum.170266. Epub 2017 Nov 15.

PMID:
29142030
15.

Endothelial dysfunction is associated with activation of the type I interferon system and platelets in patients with systemic lupus erythematosus.

Tydén H, Lood C, Gullstrand B, Nielsen CT, Heegaard NHH, Kahn R, Jönsen A, Bengtsson AA.

RMD Open. 2017 Oct 25;3(2):e000508. doi: 10.1136/rmdopen-2017-000508. eCollection 2017.

16.

Changes in circulating inflammatory markers following febrile non-haemolytic transfusion reactions to leucoreduced red cells.

Larsen R, Sandhu N, Heegaard NHH, Ullum H, von Stemann JH, Sørensen E, Nellemann DS, Hansen MB.

Vox Sang. 2018 Jan;113(1):76-79. doi: 10.1111/vox.12607. Epub 2017 Oct 11.

PMID:
29023768
17.

Biomarker Research in Parkinson's Disease Using Metabolite Profiling.

Havelund JF, Heegaard NHH, Færgeman NJK, Gramsbergen JB.

Metabolites. 2017 Aug 11;7(3). pii: E42. doi: 10.3390/metabo7030042. Review.

18.

Individual values of antineutrophil cytoplasmic antibodies do not correspond between antigen-specific assays.

Rasmussen N, Damoiseaux J, Csernok E, Heegaard NHH, Hellmich B, Paassen PV, Baslund B, Vermeersch P, Blockmans D, Tervaert JC, Bossuyt X.

Clin Chem Lab Med. 2018 Jan 26;56(2):e39-e42. doi: 10.1515/cclm-2017-0362. No abstract available.

PMID:
28755530
19.

Elevation of brain-enriched miRNAs in cerebrospinal fluid of patients with acute ischemic stroke.

Sørensen SS, Nygaard AB, Carlsen AL, Heegaard NHH, Bak M, Christensen T.

Biomark Res. 2017 Jul 11;5:24. doi: 10.1186/s40364-017-0104-9. eCollection 2017.

20.

Distinct proteome pathology of circulating microparticles in systemic lupus erythematosus.

Østergaard O, Nielsen CT, Tanassi JT, Iversen LV, Jacobsen S, Heegaard NHH.

Clin Proteomics. 2017 Jun 21;14:23. doi: 10.1186/s12014-017-9159-8. eCollection 2017.

21.

Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions.

Loke I, Østergaard O, Heegaard NHH, Packer NH, Thaysen-Andersen M.

Mol Cell Proteomics. 2017 Aug;16(8):1507-1527. doi: 10.1074/mcp.M116.066746. Epub 2017 Jun 19.

22.

Changes in kynurenine pathway metabolism in Parkinson patients with L-DOPA-induced dyskinesia.

Havelund JF, Andersen AD, Binzer M, Blaabjerg M, Heegaard NHH, Stenager E, Faergeman NJ, Gramsbergen JB.

J Neurochem. 2017 Sep;142(5):756-766. doi: 10.1111/jnc.14104. Epub 2017 Jul 11.

23.

Complexes of DNA with fluorescent dyes are effective reagents for detection of autoimmune antibodies.

Domljanovic I, Carstens A, Okholm A, Kjems J, Nielsen CT, Heegaard NHH, Astakhova K.

Sci Rep. 2017 May 15;7(1):1925. doi: 10.1038/s41598-017-02214-0.

24.

A review of studies of the proteomes of circulating microparticles: key roles for galectin-3-binding protein-expressing microparticles in vascular diseases and systemic lupus erythematosus.

Nielsen CT, Østergaard O, Rasmussen NS, Jacobsen S, Heegaard NHH.

Clin Proteomics. 2017 Apr 8;14:11. doi: 10.1186/s12014-017-9146-0. eCollection 2017. Review.

25.

Corrigendum to "Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration".

Bruun SW, Josefsen K, Tanassi JT, Marek A, Pedersen MH, Sidenius U, Haupt-Jorgensen M, Antvorskov JC, Larsen J, Heegaard NH, Buschard K.

J Diabetes Res. 2017;2017:9709704. doi: 10.1155/2017/9709704. Epub 2017 Mar 12.

26.

Decreased platelet size is associated with platelet activation and anti-phospholipid syndrome in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Nielsen CT, Heegaard NH, Linge P, Jönsen A, Hesselstrand R, Kahn R, Bengtsson AA.

Rheumatology (Oxford). 2017 Mar 1;56(3):408-416. doi: 10.1093/rheumatology/kew437.

PMID:
28031442
27.

Autoantibodies persist in relatives to systemic lupus erythematosus patients during 12 years follow-up.

Langkilde H, Voss A, Heegaard N, Laustrup H.

Lupus. 2017 Jun;26(7):723-728. doi: 10.1177/0961203316676378. Epub 2016 Nov 12.

PMID:
27831535
28.

Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration.

Bruun SW, Josefsen K, Tanassi JT, Marek A, Pedersen MH, Sidenius U, Haupt-Jorgensen M, Antvorskov JC, Larsen J, Heegaard NH, Buschard K.

J Diabetes Res. 2016;2016:2424306. Epub 2016 Oct 4. Erratum in: J Diabetes Res. 2017;2017:9709704.

29.

Quantitative Protein Profiling of Chlamydia trachomatis Growth Forms Reveals Defense Strategies Against Tryptophan Starvation.

Østergaard O, Follmann F, Olsen AW, Heegaard NH, Andersen P, Rosenkrands I.

Mol Cell Proteomics. 2016 Dec;15(12):3540-3550. Epub 2016 Oct 26.

30.

Synthetic oligonucleotide antigens modified with locked nucleic acids detect disease specific antibodies.

Samuelsen SV, Solov'yov IA, Balboni IM, Mellins E, Nielsen CT, Heegaard NH, Astakhova K.

Sci Rep. 2016 Oct 24;6:35827. doi: 10.1038/srep35827.

31.

Confirmation of an IRAK3 polymorphism as a genetic marker predicting response to anti-TNF treatment in rheumatoid arthritis.

Sode J, Vogel U, Bank S, Andersen PS, Hetland ML, Locht H, Heegaard NHH, Andersen V.

Pharmacogenomics J. 2018 Jan;18(1):81-86. doi: 10.1038/tpj.2016.66. Epub 2016 Oct 4.

PMID:
27698401
32.

Flow-Induced Dispersion Analysis for Probing Anti-dsDNA Antibody Binding Heterogeneity in Systemic Lupus Erythematosus Patients: Toward a New Approach for Diagnosis and Patient Stratification.

Poulsen NN, Pedersen ME, Østergaard J, Petersen NJ, Nielsen CT, Heegaard NH, Jensen H.

Anal Chem. 2016 Sep 20;88(18):9056-61. doi: 10.1021/acs.analchem.6b01741. Epub 2016 Sep 8.

PMID:
27571264
33.

Diurnal Variations of Human Circulating Cell-Free Micro-RNA.

Heegaard NH, Carlsen AL, Lilje B, Ng KL, Rønne ME, Jørgensen HL, Sennels H, Fahrenkrug J.

PLoS One. 2016 Aug 5;11(8):e0160577. doi: 10.1371/journal.pone.0160577. eCollection 2016.

34.

"Kill" the messenger: Targeting of cell-derived microparticles in lupus nephritis.

Nielsen CT, Rasmussen NS, Heegaard NH, Jacobsen S.

Autoimmun Rev. 2016 Jul;15(7):719-25. doi: 10.1016/j.autrev.2016.03.009. Epub 2016 Mar 9. Review.

PMID:
26970484
35.

Amyloid-β and α-Synuclein Decrease the Level of Metal-Catalyzed Reactive Oxygen Species by Radical Scavenging and Redox Silencing.

Pedersen JT, Chen SW, Borg CB, Ness S, Bahl JM, Heegaard NH, Dobson CM, Hemmingsen L, Cremades N, Teilum K.

J Am Chem Soc. 2016 Mar 30;138(12):3966-9. doi: 10.1021/jacs.5b13577. Epub 2016 Mar 21.

36.

Quantification of Epidermal Filaggrin in Human Skin and its Response to Skin Irritation.

Bandier J, Ross-Hansen K, Carlsen BC, Tanassi JT, Johansen JD, Heegaard NHH.

J Invest Dermatol. 2016 Jun;136(6):1296-1299. doi: 10.1016/j.jid.2016.01.034. Epub 2016 Feb 18. No abstract available.

37.

Circulating Extracellular microRNA in Systemic Autoimmunity.

Heegaard NHH, Carlsen AL, Skovgaard K, Heegaard PMH.

Exp Suppl. 2015;106:171-195. doi: 10.1007/978-3-0348-0955-9_8.

PMID:
26608204
38.

Impact of microRNA-130a on the neutrophil proteome.

Pedersen CC, Refsgaard JC, Østergaard O, Jensen LJ, Heegaard NH, Borregaard N, Cowland JB.

BMC Immunol. 2015 Nov 25;16:70. doi: 10.1186/s12865-015-0134-8.

39.

The Urine Proteome Profile Is Different in Neuromyelitis Optica Compared to Multiple Sclerosis: A Clinical Proteome Study.

Nielsen HH, Beck HC, Kristensen LP, Burton M, Csepany T, Simo M, Dioszeghy P, Sejbaek T, Grebing M, Heegaard NH, Illes Z.

PLoS One. 2015 Oct 13;10(10):e0139659. doi: 10.1371/journal.pone.0139659. eCollection 2015.

40.

Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis.

Sode J, Vogel U, Bank S, Andersen PS, Hetland ML, Locht H, Heegaard NH, Andersen V.

PLoS One. 2015 Oct 6;10(10):e0139781. doi: 10.1371/journal.pone.0139781. eCollection 2015.

41.

Cross-sectional study of soluble selectins, fractions of circulating microparticles and their relationship to lung and skin involvement in systemic sclerosis.

Iversen LV, Ullman S, Østergaard O, Nielsen CT, Halberg P, Karlsmark T, Heegaard NH, Jacobsen S.

BMC Musculoskelet Disord. 2015 Aug 12;16:191. doi: 10.1186/s12891-015-0653-8.

42.

Specific autoantibody profiles and disease subgroups correlate with circulating micro-RNA in systemic sclerosis.

Wuttge DM, Carlsen AL, Teku G, Steen SO, Wildt M, Vihinen M, Hesselstrand R, Heegaard NH.

Rheumatology (Oxford). 2015 Nov;54(11):2100-7. doi: 10.1093/rheumatology/kev234. Epub 2015 Jul 10.

PMID:
26163687
43.

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study.

Kruse N, Persson S, Alcolea D, Bahl JM, Baldeiras I, Capello E, Chiasserini D, Bocchio Chiavetto L, Emersic A, Engelborghs S, Eren E, Fladby T, Frisoni G, García-Ayllón MS, Genc S, Gkatzima O, Heegaard NH, Janeiro AM, Kováčech B, Kuiperij HB, Leitão MJ, Lleó A, Martins M, Matos M, Mollergard HM, Nobili F, Öhrfelt A, Parnetti L, de Oliveira CR, Rot U, Sáez-Valero J, Struyfs H, Tanassi JT, Taylor P, Tsolaki M, Vanmechelen E, Verbeek MM, Zilka N, Blennow K, Zetterberg H, Mollenhauer B.

Neurobiol Aging. 2015 Sep;36(9):2587-96. doi: 10.1016/j.neurobiolaging.2015.05.003. Epub 2015 May 15.

PMID:
26093515
44.

Circulating microRNA expression pattern separates patients with anti-neutrophil cytoplasmic antibody associated vasculitis from healthy controls.

Skoglund C, Carlsen AL, Weiner M, Kurz T, Hellmark T, Eriksson P, Heegaard NH, Segelmark M.

Clin Exp Rheumatol. 2015 Mar-Apr;33(2 Suppl 89):S-64-71. Epub 2015 May 26.

PMID:
26016752
45.

Biological properties of extracellular vesicles and their physiological functions.

Yáñez-Mó M, Siljander PR, Andreu Z, Zavec AB, Borràs FE, Buzas EI, Buzas K, Casal E, Cappello F, Carvalho J, Colás E, Cordeiro-da Silva A, Fais S, Falcon-Perez JM, Ghobrial IM, Giebel B, Gimona M, Graner M, Gursel I, Gursel M, Heegaard NH, Hendrix A, Kierulf P, Kokubun K, Kosanovic M, Kralj-Iglic V, Krämer-Albers EM, Laitinen S, Lässer C, Lener T, Ligeti E, Linē A, Lipps G, Llorente A, Lötvall J, Manček-Keber M, Marcilla A, Mittelbrunn M, Nazarenko I, Nolte-'t Hoen EN, Nyman TA, O'Driscoll L, Olivan M, Oliveira C, Pállinger É, Del Portillo HA, Reventós J, Rigau M, Rohde E, Sammar M, Sánchez-Madrid F, Santarém N, Schallmoser K, Ostenfeld MS, Stoorvogel W, Stukelj R, Van der Grein SG, Vasconcelos MH, Wauben MH, De Wever O.

J Extracell Vesicles. 2015 May 14;4:27066. doi: 10.3402/jev.v4.27066. eCollection 2015.

46.

Type I interferon-mediated skewing of the serotonin synthesis is associated with severe disease in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Klint C, Wenglén C, Nielsen CT, Heegaard NH, Jönsen A, Kahn R, Bengtsson AA.

PLoS One. 2015 Apr 21;10(4):e0125109. doi: 10.1371/journal.pone.0125109. eCollection 2015.

47.

Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis.

Nielsen CT, Østergaard O, Rekvig OP, Sturfelt G, Jacobsen S, Heegaard NH.

Lupus. 2015 Oct;24(11):1150-60. doi: 10.1177/0961203315580146. Epub 2015 Apr 2.

PMID:
25837289
48.

Immunodeficiency among children with recurrent invasive pneumococcal disease.

Ingels H, Schejbel L, Lundstedt AC, Jensen L, Laursen IA, Ryder LP, Heegaard NH, Konradsen H, Christensen JJ, Heilmann C, Marquart HV.

Pediatr Infect Dis J. 2015 Jun;34(6):644-51. doi: 10.1097/INF.0000000000000701.

49.

Associations between gastrointestinal toxicity, micro RNA and cytokine production in patients undergoing myeloablative allogeneic stem cell transplantation.

Pontoppidan PL, Jordan K, Carlsen AL, Uhlving HH, Kielsen K, Christensen M, Ifversen M, Nielsen CH, Sangild P, Heegaard NH, Heilmann C, Sengeløv H, Müller K.

Int Immunopharmacol. 2015 Mar;25(1):180-8. doi: 10.1016/j.intimp.2014.12.038. Epub 2015 Jan 20.

PMID:
25614225
50.

Changes in circulating microRNA-126 during treatment with chemotherapy and bevacizumab predicts treatment response in patients with metastatic colorectal cancer.

Hansen TF, Carlsen AL, Heegaard NH, Sørensen FB, Jakobsen A.

Br J Cancer. 2015 Feb 17;112(4):624-9. doi: 10.1038/bjc.2014.652. Epub 2015 Jan 13.

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