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Items: 1 to 50 of 59

1.

Correction to: Best practice management guidelines for fibrous dysplasia/McCune-Albright syndrome: a consensus statement from the FD/MAS international consortium.

Javaid MK, Boyce A, Appelman-Dijkstra N, Ong J, Defabianis P, Offiah A, Arundel P, Shaw N, Pos VD, Underhil A, Portero D, Heral L, Heegaard AM, Masi L, Monsell F, Stanton R, Dijkstra PDS, Brandi ML, Chapurlat R, Hamdy NAT, Collins MT.

Orphanet J Rare Dis. 2019 Nov 21;14(1):267. doi: 10.1186/s13023-019-1255-6.

2.

The nociceptin/orphaninFQ receptor system as a target to alleviate cancer-induced bone pain in rats: Model validation and pharmacological evaluation.

Sliepen SHJ, Korioth J, Christoph T, Tzschentke TM, Diaz-delCastillo M, Heegaard AM, Rutten K.

Br J Pharmacol. 2019 Nov 13. doi: 10.1111/bph.14899. [Epub ahead of print]

PMID:
31724155
3.

Exploring the Patients' Perception of Background and Breakthrough Pain: A McGill Pain Questionnaire Inquiry in Patients with Bone Cancer Pain.

Hansen RB, Frost CØ, Sonne NM, Johnsen AT, Heegaard AM.

J Palliat Med. 2019 Aug;22(8):881-883. doi: 10.1089/jpm.2018.0621. No abstract available.

PMID:
31380726
4.

Cancer-induced Bone Pain Impairs Burrowing Behaviour in Mouse and Rat.

Sliepen SHJ, Diaz-Delcastillo M, Korioth J, Olsen RB, Appel CK, Christoph T, Heegaard AM, Rutten K.

In Vivo. 2019 Jul-Aug;33(4):1125-1132. doi: 10.21873/invivo.11582.

5.

Best practice management guidelines for fibrous dysplasia/McCune-Albright syndrome: a consensus statement from the FD/MAS international consortium.

Javaid MK, Boyce A, Appelman-Dijkstra N, Ong J, Defabianis P, Offiah A, Arundel P, Shaw N, Pos VD, Underhil A, Portero D, Heral L, Heegaard AM, Masi L, Monsell F, Stanton R, Dijkstra PDS, Brandi ML, Chapurlat R, Hamdy NAT, Collins MT.

Orphanet J Rare Dis. 2019 Jun 13;14(1):139. doi: 10.1186/s13023-019-1102-9. Erratum in: Orphanet J Rare Dis. 2019 Nov 21;14(1):267.

6.

Author Correction: The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain.

Appel CK, Gallego-Pedersen S, Andersen L, Blancheflor Kristensen S, Ding M, Falk S, Sayilekshmy M, Gabel-Jensen C, Heegaard AM.

Sci Rep. 2019 May 9;9(1):7399. doi: 10.1038/s41598-019-43721-6.

7.

Innervation is higher above Bone Remodeling Surfaces and in Cortical Pores in Human Bone: Lessons from patients with primary hyperparathyroidism.

Sayilekshmy M, Hansen RB, Delaissé JM, Rolighed L, Andersen TL, Heegaard AM.

Sci Rep. 2019 Mar 29;9(1):5361. doi: 10.1038/s41598-019-41779-w.

8.

Vitamin D levels and cancer incidence in 217,244 individuals from primary health care in Denmark.

Vojdeman FJ, Madsen CM, Frederiksen K, Durup D, Olsen A, Hansen L, Heegaard AM, Lind B, Tjønneland A, Jørgensen HL, Schwarz P.

Int J Cancer. 2019 Jul 15;145(2):338-346. doi: 10.1002/ijc.32105. Epub 2019 Jan 20.

PMID:
30613979
9.

Chronic high dose P2X7 receptor inhibition exacerbates cancer-induced bone pain.

Falk S, Appel CK, Bennedbæk HB, Al-Dihaissy T, Unger A, Dinkel K, Heegaard AM.

Eur J Pharmacol. 2019 Feb 15;845:48-55. doi: 10.1016/j.ejphar.2018.12.032. Epub 2018 Dec 22.

PMID:
30582910
10.

Decitabine attenuates nociceptive behavior in a murine model of bone cancer pain.

Appel CK, Scheff NN, Viet CT, Schmidt BL, Heegaard AM.

Pain. 2019 Mar;160(3):619-631. doi: 10.1097/j.pain.0000000000001442.

PMID:
30422869
11.

Neuropeptide Y is Up-regulated and Induces Antinociception in Cancer-induced Bone Pain.

Diaz-delCastillo M, Christiansen SH, Appel CK, Falk S, Woldbye DPD, Heegaard AM.

Neuroscience. 2018 Aug 1;384:111-119. doi: 10.1016/j.neuroscience.2018.05.025. Epub 2018 May 29.

PMID:
29852245
12.

The effect of gender on early colonic anastomotic wound healing.

Kjaer M, Kristjánsdóttir H, Andersen L, Heegaard AM, Ågren MS, Jorgensen LN.

Int J Colorectal Dis. 2018 Sep;33(9):1269-1276. doi: 10.1007/s00384-018-3089-4. Epub 2018 May 31.

PMID:
29850942
13.

The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain.

Kristensen PJ, Gegelashvili G, Munro G, Heegaard AM, Bjerrum OJ.

Eur J Pain. 2018 Feb;22(2):282-294. doi: 10.1002/ejp.1117. Epub 2017 Oct 6.

PMID:
28984398
14.

Neuropeptide Y and its Involvement in Chronic Pain.

Diaz-delCastillo M, Woldbye DPD, Heegaard AM.

Neuroscience. 2018 Sep 1;387:162-169. doi: 10.1016/j.neuroscience.2017.08.050. Epub 2017 Sep 7. Review.

PMID:
28890052
15.

Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach.

Papathanasiou T, Juul RV, Gabel-Jensen C, Kreilgaard M, Heegaard AM, Lund TM.

AAPS J. 2017 Nov;19(6):1804-1813. doi: 10.1208/s12248-017-0140-2. Epub 2017 Aug 29.

PMID:
28853055
16.

The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain.

Appel CK, Gallego-Pedersen S, Andersen L, Blancheflor Kristensen S, Ding M, Falk S, Sayilekshmy M, Gabel-Jensen C, Heegaard AM.

Sci Rep. 2017 Jul 6;7(1):4792. doi: 10.1038/s41598-017-05029-1. Erratum in: Sci Rep. 2019 May 9;9(1):7399.

17.

Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

Kristensen PJ, Heegaard AM, Hestehave S, Jeggo RD, Bjerrum OJ, Munro G.

Eur J Pain. 2017 Apr;21(4):692-704. doi: 10.1002/ejp.973. Epub 2016 Nov 2.

PMID:
27805755
18.

Bone pain: current and future treatments.

Frost CØ, Hansen RR, Heegaard AM.

Curr Opin Pharmacol. 2016 Jun;28:31-7. doi: 10.1016/j.coph.2016.02.007. Epub 2016 Mar 2. Review.

PMID:
26940053
19.

Effect of sex in the MRMT-1 model of cancer-induced bone pain.

Falk S, Al-Dihaissy T, Mezzanotte L, Heegaard AM.

Version 3. F1000Res. 2015 Jul 31 [revised 2015 Jan 1];4:445. doi: 10.12688/f1000research.6827.3. eCollection 2015.

20.

Co-administration of morphine and gabapentin leads to dose dependent synergistic effects in a rat model of postoperative pain.

Papathanasiou T, Juul RV, Heegaard AM, Kreilgaard M, Lund TM.

Eur J Pharm Sci. 2016 Jan 20;82:97-105. doi: 10.1016/j.ejps.2015.11.015. Epub 2015 Nov 21.

PMID:
26610393
21.

A Reverse J-Shaped Association Between Serum 25-Hydroxyvitamin D and Cardiovascular Disease Mortality: The CopD Study.

Durup D, Jørgensen HL, Christensen J, Tjønneland A, Olsen A, Halkjær J, Lind B, Heegaard AM, Schwarz P.

J Clin Endocrinol Metab. 2015 Jun;100(6):2339-46. doi: 10.1210/jc.2014-4551. Epub 2015 Feb 24.

PMID:
25710567
22.

P2X7 receptor-mediated analgesia in cancer-induced bone pain.

Falk S, Schwab SD, Frøsig-Jørgensen M, Clausen RP, Dickenson AH, Heegaard AM.

Neuroscience. 2015 Apr 16;291:93-105. doi: 10.1016/j.neuroscience.2015.02.011. Epub 2015 Feb 14.

PMID:
25686524
23.

Randall Selitto pressure algometry for assessment of bone-related pain in rats.

Falk S, Ipsen DH, Appel CK, Ugarak A, Durup D, Dickenson AH, Heegaard AM.

Eur J Pain. 2015 Mar;19(3):305-12. doi: 10.1002/ejp.547.

PMID:
25057115
24.

Spinal neuronal correlates of tapentadol analgesia in cancer pain: a back-translational approach.

Falk S, Patel R, Heegaard A, Mercadante S, Dickenson AH.

Eur J Pain. 2015 Feb;19(2):152-8. doi: 10.1002/ejp.530. Epub 2014 Jun 11.

PMID:
24917026
25.

Pain without nociceptors? Nav1.7-independent pain mechanisms.

Minett MS, Falk S, Santana-Varela S, Bogdanov YD, Nassar MA, Heegaard AM, Wood JN.

Cell Rep. 2014 Jan 30;6(2):301-12. doi: 10.1016/j.celrep.2013.12.033. Epub 2014 Jan 16.

26.

Influence of sex differences on the progression of cancer-induced bone pain.

Falk S, Uldall M, Appel C, Ding M, Heegaard AM.

Anticancer Res. 2013 May;33(5):1963-9.

PMID:
23645744
27.

Impaired behavioural pain responses in hph-1 mice with inherited deficiency in GTP cyclohydrolase 1 in models of inflammatory pain.

Nasser A, Bjerrum OJ, Heegaard AM, Møller AT, Larsen M, Dalbøge LS, Dupont E, Jensen TS, Møller LB.

Mol Pain. 2013 Feb 19;9:5. doi: 10.1186/1744-8069-9-5.

28.

The role of purinergic receptors in cancer-induced bone pain.

Falk S, Uldall M, Heegaard AM.

J Osteoporos. 2012;2012:758181. doi: 10.1155/2012/758181. Epub 2012 Oct 3.

29.

Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice.

Hansen RR, Nasser A, Falk S, Baldvinsson SB, Ohlsson PH, Bahl JM, Jarvis MF, Ding M, Heegaard AM.

Eur J Pharmacol. 2012 Aug 5;688(1-3):27-34. doi: 10.1016/j.ejphar.2012.05.008. Epub 2012 May 22.

PMID:
22634164
30.

A reverse J-shaped association of all-cause mortality with serum 25-hydroxyvitamin D in general practice: the CopD study.

Durup D, Jørgensen HL, Christensen J, Schwarz P, Heegaard AM, Lind B.

J Clin Endocrinol Metab. 2012 Aug;97(8):2644-52. doi: 10.1210/jc.2012-1176. Epub 2012 May 9.

PMID:
22573406
31.

P2X7 receptor-deficient mice are susceptible to bone cancer pain.

Hansen RR, Nielsen CK, Nasser A, Thomsen SI, Eghorn LF, Pham Y, Schulenburg C, Syberg S, Ding M, Stojilkovic SS, Jorgensen NR, Heegaard AM.

Pain. 2011 Aug;152(8):1766-76. doi: 10.1016/j.pain.2011.03.024. Epub 2011 May 11.

32.

Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity.

Ågren MS, Andersen TL, Andersen L, Schiødt CB, Surve V, Andreassen TT, Risteli J, Franzén LE, Delaissé JM, Heegaard AM, Jorgensen LN.

Int J Colorectal Dis. 2011 Mar;26(3):329-37. doi: 10.1007/s00384-010-1106-3. Epub 2010 Dec 31.

PMID:
21193914
33.

Cancer-induced bone loss and associated pain-related behavior is reduced by risedronate but not its phosphonocarboxylate analog NE-10790.

Hald A, Hansen RR, Thomsen MW, Ding M, Croucher PI, Gallagher O, Ebetino FH, Kassem M, Heegaard AM.

Int J Cancer. 2009 Sep 1;125(5):1177-85. doi: 10.1002/ijc.24436.

34.

Potential roles for the small leucine-rich proteoglycans biglycan and fibromodulin in ectopic ossification of tendon induced by exercise and in modulating rotarod performance.

Kilts T, Ameye L, Syed-Picard F, Ono M, Berendsen AD, Oldberg A, Heegaard AM, Bi Y, Young MF.

Scand J Med Sci Sports. 2009 Aug;19(4):536-46. doi: 10.1111/j.1600-0838.2009.00909.x. Epub 2009 Apr 13.

35.

Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain.

Hald A, Ding M, Egerod K, Hansen RR, Konradsen D, Jørgensen SG, Atalay B, Nasser A, Bjerrum OJ, Heegaard AM.

Pharmacol Biochem Behav. 2008 Nov;91(1):38-46. doi: 10.1016/j.pbb.2008.04.021. Epub 2008 Jun 20.

PMID:
18611408
36.

Effect of parenteral zinc sulfate on colon anastomosis repair in the rat.

Agren MS, Andersen L, Heegaard AM, Jorgensen LN.

Int J Colorectal Dis. 2008 Sep;23(9):857-61. doi: 10.1007/s00384-008-0501-5. Epub 2008 Jun 18.

PMID:
18563421
37.

Estrogenic uterovaginal effects of oral estetrol in the modified Allen-Doisy test.

Heegaard AM, Holinka CF, Kenemans P, Coelingh Bennink HJ.

Climacteric. 2008;11 Suppl 1:22-8. doi: 10.1080/13697130701842490.

PMID:
18464018
38.

Oral bioavailability and bone-sparing effects of estetrol in an osteoporosis model.

Coelingh Bennink HJ, Heegaard AM, Visser M, Holinka CF, Christiansen C.

Climacteric. 2008;11 Suppl 1:2-14. doi: 10.1080/13697130701798692.

PMID:
18464016
39.

Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain.

Hald A, Nedergaard S, Hansen RR, Ding M, Heegaard AM.

Eur J Pain. 2009 Feb;13(2):138-45. doi: 10.1016/j.ejpain.2008.03.014. Epub 2008 May 21.

PMID:
18499488
40.

Doxycycline-coated sutures improve mechanical strength of intestinal anastomoses.

Pasternak B, Rehn M, Andersen L, Agren MS, Heegaard AM, Tengvall P, Aspenberg P.

Int J Colorectal Dis. 2008 Mar;23(3):271-6. Epub 2007 Nov 28.

PMID:
18043927
41.

Biglycan deficiency causes spontaneous aortic dissection and rupture in mice.

Heegaard AM, Corsi A, Danielsen CC, Nielsen KL, Jorgensen HL, Riminucci M, Young MF, Bianco P.

Circulation. 2007 May 29;115(21):2731-8. Epub 2007 May 14.

PMID:
17502576
42.

Small leucine-rich proteoglycans in the aging skeleton.

Young MF, Bi Y, Ameye L, Xu T, Wadhwa S, Heegaard A, Kilts T, Chen XD.

J Musculoskelet Neuronal Interact. 2006 Oct-Dec;6(4):364-5.

43.

Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts.

Bi Y, Nielsen KL, Kilts TM, Yoon A, A Karsdal M, Wimer HF, Greenfield EM, Heegaard AM, Young MF.

Bone. 2006 Jun;38(6):778-86. Epub 2005 Dec 20.

PMID:
16364709
44.

Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption.

Karsdal MA, Henriksen K, Sørensen MG, Gram J, Schaller S, Dziegiel MH, Heegaard AM, Christophersen P, Martin TJ, Christiansen C, Bollerslev J.

Am J Pathol. 2005 Feb;166(2):467-76.

45.

Transforming growth factor beta stimulation of biglycan gene expression is potentially mediated by sp1 binding factors.

Heegaard AM, Xie Z, Young MF, Nielsen KL.

J Cell Biochem. 2004 Oct 15;93(3):463-75.

PMID:
15372625
46.

The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation.

Schaller S, Henriksen K, Sveigaard C, Heegaard AM, Hélix N, Stahlhut M, Ovejero MC, Johansen JV, Solberg H, Andersen TL, Hougaard D, Berryman M, Shiødt CB, Sørensen BH, Lichtenberg J, Christophersen P, Foged NT, Delaissé JM, Engsig MT, Karsdal MA.

J Bone Miner Res. 2004 Jul;19(7):1144-53. Epub 2004 Mar 1. Erratum in: J Bone Miner Res. 2004 Aug;19(8):1378.

47.

Measurement of tumor load and distribution in a model of cancer-induced osteolysis: a necessary precaution when testing novel anti-resorptive therapies.

Amhlaoibh RN, Hoegh-Andersen P, Brünner N, Sørensen A, Winding B, Holst-Hansen C, Karsdal MA, Engsig MT, Delaissé JM, Heegaard AM.

Clin Exp Metastasis. 2004;21(1):65-74.

PMID:
15065604
48.

Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application.

Høegh-Andersen P, Tankó LB, Andersen TL, Lundberg CV, Mo JA, Heegaard AM, Delaissé JM, Christgau S.

Arthritis Res Ther. 2004;6(2):R169-80. Epub 2004 Feb 19.

49.

Biglycan deficiency interferes with ovariectomy-induced bone loss.

Nielsen KL, Allen MR, Bloomfield SA, Andersen TL, Chen XD, Poulsen HS, Young MF, Heegaard AM.

J Bone Miner Res. 2003 Dec;18(12):2152-8.

50.

Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice.

Winding B, NicAmhlaoibh R, Misander H, Høegh-Andersen P, Andersen TL, Holst-Hansen C, Heegaard AM, Foged NT, Brünner N, Delaissé JM.

Clin Cancer Res. 2002 Jun;8(6):1932-9.

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