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Items: 35

1.

Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data.

Cheng DT, Cheng J, Mitchell TN, Syed A, Zehir A, Mensah NYT, Oultache A, Nafa K, Levine RL, Arcila ME, Berger MF, Hedvat CV.

J Mol Diagn. 2014 Sep;16(5):504-518. doi: 10.1016/j.jmoldx.2014.05.006. Epub 2014 Jul 10.

2.

Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells.

Dickson MA, Papadopoulos EB, Hedvat CV, Jhanwar SC, Brentjens RJ.

Leuk Res Rep. 2014 May 20;3(2):38-41. doi: 10.1016/j.lrr.2014.04.001. eCollection 2014.

3.

Association of quantitative assessment of the intrafollicular proliferation index with outcome in follicular lymphoma.

Kedmi M, Hedvat CV, Maragulia J, Zhang Z, Zelenetz AD.

Br J Haematol. 2014 Mar;164(5):646-52. doi: 10.1111/bjh.12667. Epub 2013 Dec 5.

PMID:
24303881
4.

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing.

Frampton GM, Fichtenholtz A, Otto GA, Wang K, Downing SR, He J, Schnall-Levin M, White J, Sanford EM, An P, Sun J, Juhn F, Brennan K, Iwanik K, Maillet A, Buell J, White E, Zhao M, Balasubramanian S, Terzic S, Richards T, Banning V, Garcia L, Mahoney K, Zwirko Z, Donahue A, Beltran H, Mosquera JM, Rubin MA, Dogan S, Hedvat CV, Berger MF, Pusztai L, Lechner M, Boshoff C, Jarosz M, Vietz C, Parker A, Miller VA, Ross JS, Curran J, Cronin MT, Stephens PJ, Lipson D, Yelensky R.

Nat Biotechnol. 2013 Nov;31(11):1023-31. doi: 10.1038/nbt.2696. Epub 2013 Oct 20.

5.

Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus.

Liu Y, Liu F, Yu H, Zhao X, Sashida G, Deblasio A, Harr M, She QB, Chen Z, Lin HK, Di Giandomenico S, Elf SE, Yang Y, Miyata Y, Huang G, Menendez S, Mellinghoff IK, Rosen N, Pandolfi PP, Hedvat CV, Nimer SD.

Sci Signal. 2012 Oct 23;5(247):ra77. doi: 10.1126/scisignal.2003199.

6.

Regulatory T cell infiltration predicts outcome following resection of colorectal cancer liver metastases.

Katz SC, Bamboat ZM, Maker AV, Shia J, Pillarisetty VG, Yopp AC, Hedvat CV, Gonen M, Jarnagin WR, Fong Y, D'Angelica MI, DeMatteo RP.

Ann Surg Oncol. 2013 Mar;20(3):946-55. doi: 10.1245/s10434-012-2668-9. Epub 2012 Sep 26.

7.

Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice.

Xiong X, Chorzalska A, Dubielecka PM, White JR, Vedvyas Y, Hedvat CV, Haimovitz-Friedman A, Koutcher JA, Reimand J, Bader GD, Sawicki JA, Kotula L.

Oncogenesis. 2012 Sep 3;1:e26. doi: 10.1038/oncsis.2012.28.

8.

Importance of day 21 BM chimerism in sustained neutrophil engraftment following double-unit cord blood transplantation.

Avery S, Voss MH, Gonzales AM, Lubin M, Castro-Malaspina H, Giralt S, Kernan NA, Scaradavou A, Hedvat CV, Stevens CE, Barker JN.

Bone Marrow Transplant. 2012 Aug;47(8):1056-60. doi: 10.1038/bmt.2011.236. Epub 2011 Dec 5.

9.

Human epidermal growth factor receptor 2 testing in gastroesophageal cancer: correlation between immunohistochemistry and fluorescence in situ hybridization.

Tafe LJ, Janjigian YY, Zaidinski M, Hedvat CV, Hameed MR, Tang LH, Hicks JB, Shah MA, Barbashina V.

Arch Pathol Lab Med. 2011 Nov;135(11):1460-5. doi: 10.5858/arpa.2010-0541-OA.

PMID:
22032573
10.

High frequency of IDH-1 mutation links glioneuronal tumors with neuropil-like islands to diffuse astrocytomas.

Huse JT, Nafa K, Shukla N, Kastenhuber ER, Lavi E, Hedvat CV, Ladanyi M, Rosenblum MK.

Acta Neuropathol. 2011 Sep;122(3):367-9. doi: 10.1007/s00401-011-0855-6. Epub 2011 Jul 14. No abstract available.

11.

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML.

Payne EM, Bolli N, Rhodes J, Abdel-Wahab OI, Levine R, Hedvat CV, Stone R, Khanna-Gupta A, Sun H, Kanki JP, Gazda HT, Beggs AH, Cotter FE, Look AT.

Blood. 2011 Jul 28;118(4):903-15. doi: 10.1182/blood-2010-11-318022. Epub 2011 Jun 7.

12.

Blood consult: acute myeloid leukemia and the t(8;21)(q22;22).

Park JH, Hedvat CV, Tallman MS.

Blood. 2011 Mar 10;117(10):2775-7. doi: 10.1182/blood-2011-01-326819. Epub 2011 Feb 1. No abstract available.

PMID:
21285436
13.

Digital microscopy: past, present, and future.

Hedvat CV.

Arch Pathol Lab Med. 2010 Nov;134(11):1666-70. doi: 10.1043/2009-0579-RAR1.1. Review.

PMID:
21043820
14.

PHF6 mutations in adult acute myeloid leukemia.

Van Vlierberghe P, Patel J, Abdel-Wahab O, Lobry C, Hedvat CV, Balbin M, Nicolas C, Payer AR, Fernandez HF, Tallman MS, Paietta E, Melnick A, Vandenberghe P, Speleman F, Aifantis I, Cools J, Levine R, Ferrando A.

Leukemia. 2011 Jan;25(1):130-4. doi: 10.1038/leu.2010.247. Epub 2010 Oct 29.

15.

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

Ward PS, Patel J, Wise DR, Abdel-Wahab O, Bennett BD, Coller HA, Cross JR, Fantin VR, Hedvat CV, Perl AE, Rabinowitz JD, Carroll M, Su SM, Sharp KA, Levine RL, Thompson CB.

Cancer Cell. 2010 Mar 16;17(3):225-34. doi: 10.1016/j.ccr.2010.01.020. Epub 2010 Feb 18.

16.

Prognostic impact of proliferative index determined by quantitative image analysis and the International Prognostic Index in patients with mantle cell lymphoma.

Schaffel R, Hedvat CV, Teruya-Feldstein J, Persky D, Maragulia J, Lin D, Portlock CS, Moskowitz CH, Zelenetz AD.

Ann Oncol. 2010 Jan;21(1):133-9. doi: 10.1093/annonc/mdp495.

17.

PIK3CA mutation associates with improved outcome in breast cancer.

Kalinsky K, Jacks LM, Heguy A, Patil S, Drobnjak M, Bhanot UK, Hedvat CV, Traina TA, Solit D, Gerald W, Moynahan ME.

Clin Cancer Res. 2009 Aug 15;15(16):5049-59. doi: 10.1158/1078-0432.CCR-09-0632. Epub 2009 Aug 11.

18.

Isolation of avian paramyxovirus 1 from a patient with a lethal case of pneumonia.

Goebel SJ, Taylor J, Barr BC, Kiehn TE, Castro-Malaspina HR, Hedvat CV, Rush-Wilson KA, Kelly CD, Davis SW, Samsonoff WA, Hurst KR, Behr MJ, Masters PS.

J Virol. 2007 Nov;81(22):12709-14. Epub 2007 Sep 12.

19.

Tumor promoting properties of the ETS protein MEF in ovarian cancer.

Yao JJ, Liu Y, Lacorazza HD, Soslow RA, Scandura JM, Nimer SD, Hedvat CV.

Oncogene. 2007 Jun 7;26(27):4032-7. Epub 2007 Jan 8.

PMID:
17213815
20.

Patterns of expression of cell cycle/apoptosis genes along the spectrum of thyroid carcinoma progression.

Saltman B, Singh B, Hedvat CV, Wreesmann VB, Ghossein R.

Surgery. 2006 Dec;140(6):899-905; discussion 905-6.

PMID:
17188136
21.

The ETS protein MEF is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2.

Liu Y, Hedvat CV, Mao S, Zhu XH, Yao J, Nguyen H, Koff A, Nimer SD.

Mol Cell Biol. 2006 Apr;26(8):3114-23.

22.

Doxorubicin and dexamethasone followed by thalidomide and dexamethasone is an effective well tolerated initial therapy for multiple myeloma.

Hassoun H, Reich L, Klimek VM, Dhodapkar M, Cohen A, Kewalramani T, Zimman R, Drake L, Riedel ER, Hedvat CV, Teruya-Feldstein J, Filippa DA, Fleisher M, Nimer SD, Comenzo RL.

Br J Haematol. 2006 Jan;132(2):155-61.

PMID:
16398649
23.

Expression of p63 in diffuse large B-cell lymphoma.

Hedvat CV, Teruya-Feldstein J, Puig P, Capodieci P, Dudas M, Pica N, Qin J, Cordon-Cardo C, Di Como CJ.

Appl Immunohistochem Mol Morphol. 2005 Sep;13(3):237-42.

PMID:
16082248
24.

Differential expression patterns of c-REL protein in classic and nodular lymphocyte predominant Hodgkin lymphoma.

Xiao Q, Shen N, Hedvat CV, Moskowitz CH, Sussman LK, Filippa DA, Zelenetz AD, Houldsworth J, Chaganti RS, Teruya-Feldstein J.

Appl Immunohistochem Mol Morphol. 2004 Sep;12(3):211-5.

PMID:
15551733
25.

Wilms Tumor Gene (WT1) and p53 expression in endometrial carcinomas: a study of 130 cases using a tissue microarray.

Dupont J, Wang X, Marshall DS, Leitao M, Hedvat CV, Hummer A, Thaler H, O'Reilly RJ, Soslow RA.

Gynecol Oncol. 2004 Aug;94(2):449-55.

PMID:
15297187
26.

Expression of cancer-testis antigens in endometrial carcinomas using a tissue microarray.

Chitale DA, Jungbluth AA, Marshall DS, Leitao MM, Hedvat CV, Kolb D, Spagnoli GC, Iversen K, Soslow RA.

Mod Pathol. 2005 Jan;18(1):119-26.

27.

Myeloid ELF1-like factor is a potent activator of interleukin-8 expression in hematopoietic cells.

Hedvat CV, Yao J, Sokolic RA, Nimer SD.

J Biol Chem. 2004 Feb 20;279(8):6395-400. Epub 2003 Nov 17. Erratum in: J Biol Chem. 2006 Mar 31;281(13):8996.

28.

Melan-A (A103) and inhibin expression in ovarian neoplasms.

Yao DX, Soslow RA, Hedvat CV, Leitao M, Baergen RN.

Appl Immunohistochem Mol Morphol. 2003 Sep;11(3):244-9.

PMID:
12966351
29.

Insights into extramedullary tumour cell growth revealed by expression profiling of human plasmacytomas and multiple myeloma.

Hedvat CV, Comenzo RL, Teruya-Feldstein J, Olshen AB, Ely SA, Osman K, Zhang Y, Kalakonda N, Nimer SD.

Br J Haematol. 2003 Sep;122(5):728-44. Erratum in: Br J Haematol. 2003 Nov;123(3):563.

PMID:
12930383
30.

Expression of cancer/testis (CT) antigens MAGE-A1, MAGE-A3, MAGE-A4, CT-7, and NY-ESO-1 in malignant gammopathies is heterogeneous and correlates with site, stage and risk status of disease.

Dhodapkar MV, Osman K, Teruya-Feldstein J, Filippa D, Hedvat CV, Iversen K, Kolb D, Geller MD, Hassoun H, Kewalramani T, Comenzo RL, Coplan K, Chen YT, Jungbluth AA.

Cancer Immun. 2003 Jul 23;3:9.

31.

Tissue microarray molecular profiling of early, node-negative adenocarcinoma of the rectum: a comprehensive analysis.

Hoos A, Nissan A, Stojadinovic A, Shia J, Hedvat CV, Leung DH, Paty PB, Klimstra D, Cordon-Cardo C, Wong WD.

Clin Cancer Res. 2002 Dec;8(12):3841-9.

32.

Application of tissue microarray technology to the study of non-Hodgkin's and Hodgkin's lymphoma.

Hedvat CV, Hegde A, Chaganti RS, Chen B, Qin J, Filippa DA, Nimer SD, Teruya-Feldstein J.

Hum Pathol. 2002 Oct;33(10):968-74.

PMID:
12395368
33.

p63 expression profiles in human normal and tumor tissues.

Di Como CJ, Urist MJ, Babayan I, Drobnjak M, Hedvat CV, Teruya-Feldstein J, Pohar K, Hoos A, Cordon-Cardo C.

Clin Cancer Res. 2002 Feb;8(2):494-501.

34.

Macrophage-derived chemokine expression in classical Hodgkin's lymphoma: application of tissue microarrays.

Hedvat CV, Jaffe ES, Qin J, Filippa DA, Cordon-Cardo C, Tosato G, Nimer SD, Teruya-Feldstein J.

Mod Pathol. 2001 Dec;14(12):1270-6.

35.

The isolation and characterization of MINOR, a novel mitogen-inducible nuclear orphan receptor.

Hedvat CV, Irving SG.

Mol Endocrinol. 1995 Dec;9(12):1692-700.

PMID:
8614405

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