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Items: 1 to 50 of 251

1.

Polymers with distinctive anticancer mechanism that kills MDR cancer cells and inhibits tumor metastasis.

Zhong G, Yang C, Liu S, Zheng Y, Lou W, Teo JY, Bao C, Cheng W, Tan JPK, Gao S, Park N, Venkataraman S, Huang Y, Tan MH, Wang X, Hedrick JL, Fan W, Yang YY.

Biomaterials. 2019 Apr;199:76-87. doi: 10.1016/j.biomaterials.2019.01.036. Epub 2019 Jan 25.

PMID:
30771551
2.

Effective encapsulation of apomorphine into biodegradable polymeric nanoparticles through a reversible chemical bond for delivery across the blood-brain barrier.

Tan JPK, Voo ZX, Lim S, Venkataraman S, Ng KM, Gao S, Hedrick JL, Yang YY.

Nanomedicine. 2019 Feb 6. pii: S1549-9634(19)30026-7. doi: 10.1016/j.nano.2019.01.014. [Epub ahead of print]

PMID:
30738234
3.

Nanocombinatorics with Cantilever-Free Scanning Probe Arrays.

Brown KA, Hedrick JL, Eichelsdoerfer DJ, Mirkin CA.

ACS Nano. 2018 Dec 18. doi: 10.1021/acsnano.8b08185. [Epub ahead of print]

PMID:
30561191
4.

Catalyst discovery through megalibraries of nanomaterials.

Kluender EJ, Hedrick JL, Brown KA, Rao R, Meckes B, Du JS, Moreau LM, Maruyama B, Mirkin CA.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):40-45. doi: 10.1073/pnas.1815358116. Epub 2018 Dec 17.

PMID:
30559201
5.

Hydrogels with prolonged release of therapeutic antibody: Block junction chemistry modification of 'ABA' copolymers provides superior anticancer efficacy.

Yang C, Lee A, Gao S, Liu S, Hedrick JL, Yang YY.

J Control Release. 2019 Jan 10;293:193-200. doi: 10.1016/j.jconrel.2018.11.026. Epub 2018 Dec 4.

PMID:
30521830
6.

Disease-directed design of biodegradable polymers: Reactive oxygen species and pH-responsive micellar nanoparticles for anticancer drug delivery.

Leong J, Chin W, Ke X, Gao S, Kong H, Hedrick JL, Yang YY.

Nanomedicine. 2018 Nov;14(8):2666-2677. doi: 10.1016/j.nano.2018.06.015. Epub 2018 Jul 12.

PMID:
30017961
7.

Dual pH-Responsive Shell-Cleavable Polycarbonate Micellar Nanoparticles for in Vivo Anticancer Drug Delivery.

Liu S, Ono RJ, Yang C, Gao S, Ming Tan JY, Hedrick JL, Yang YY.

ACS Appl Mater Interfaces. 2018 Jun 13;10(23):19355-19364. doi: 10.1021/acsami.8b01954. Epub 2018 May 29.

PMID:
29757607
8.

Injectable Coacervate Hydrogel for Delivery of Anticancer Drug-Loaded Nanoparticles in vivo.

Lee ALZ, Voo ZX, Chin W, Ono RJ, Yang C, Gao S, Hedrick JL, Yang YY.

ACS Appl Mater Interfaces. 2018 Apr 25;10(16):13274-13282. doi: 10.1021/acsami.7b14319. Epub 2018 Apr 16.

PMID:
29595244
9.

Addressing Drug Resistance in Cancer with Macromolecular Chemotherapeutic Agents.

Park NH, Cheng W, Lai F, Yang C, Florez de Sessions P, Periaswamy B, Wenhan Chu C, Bianco S, Liu S, Venkataraman S, Chen Q, Yang YY, Hedrick JL.

J Am Chem Soc. 2018 Mar 28;140(12):4244-4252. doi: 10.1021/jacs.7b11468. Epub 2018 Mar 15.

PMID:
29504396
10.

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset.

Chin W, Zhong G, Pu Q, Yang C, Lou W, De Sessions PF, Periaswamy B, Lee A, Liang ZC, Ding X, Gao S, Chu CW, Bianco S, Bao C, Tong YW, Fan W, Wu M, Hedrick JL, Yang YY.

Nat Commun. 2018 Mar 2;9(1):917. doi: 10.1038/s41467-018-03325-6.

11.

Peptide-Functionalized Polyurethane Coatings Prepared via Grafting-To Strategy to Selectively Promote Endothelialization.

Ding X, Chin W, Lee CN, Hedrick JL, Yang YY.

Adv Healthc Mater. 2018 Mar;7(5). doi: 10.1002/adhm.201700944. Epub 2017 Dec 4.

PMID:
29205938
12.

Erratum: Organocatalyzed synthesis of fluorinated poly(aryl thioethers).

Park NH, Gomes GDP, Fevre M, Jones GO, Alabugin IV, Hedrick JL.

Nat Commun. 2017 Nov 13;8(1):1553. doi: 10.1038/s41467-017-01129-8.

13.

Supramolecular nanofibers self-assembled from cationic small molecules derived from repurposed poly(ethylene teraphthalate) for antibiotic delivery.

Liu S, Fukushima K, Venkataraman S, Hedrick JL, Yang YY.

Nanomedicine. 2018 Jan;14(1):165-172. doi: 10.1016/j.nano.2017.09.007. Epub 2017 Sep 30.

PMID:
28974393
14.

Organocatalyzed synthesis of fluorinated poly(aryl thioethers).

Park NH, Gomes GDP, Fevre M, Jones GO, Alabugin IV, Hedrick JL.

Nat Commun. 2017 Aug 1;8(1):166. doi: 10.1038/s41467-017-00186-3. Erratum in: Nat Commun. 2017 Nov 13;8(1):1553.

15.

Structural Evolution of Three-Component Nanoparticles in Polymer Nanoreactors.

Chen PC, Du JS, Meckes B, Huang L, Xie Z, Hedrick JL, Dravid VP, Mirkin CA.

J Am Chem Soc. 2017 Jul 26;139(29):9876-9884. doi: 10.1021/jacs.7b03163. Epub 2017 Jul 12.

PMID:
28700228
16.

Biodegradable Strain-Promoted Click Hydrogels for Encapsulation of Drug-Loaded Nanoparticles and Sustained Release of Therapeutics.

Ono RJ, Lee ALZ, Voo ZX, Venkataraman S, Koh BW, Yang YY, Hedrick JL.

Biomacromolecules. 2017 Aug 14;18(8):2277-2285. doi: 10.1021/acs.biomac.7b00377. Epub 2017 Jul 21.

PMID:
28682629
17.

Broad Spectrum Macromolecular Antimicrobials with Biofilm Disruption Capability and In Vivo Efficacy.

Tan JPK, Coady DJ, Sardon H, Yuen A, Gao S, Lim SW, Liang ZC, Tan EW, Venkataraman S, Engler AC, Fevre M, Ono R, Yang YY, Hedrick JL.

Adv Healthc Mater. 2017 Aug;6(16). doi: 10.1002/adhm.201601420. Epub 2017 May 15.

PMID:
28504348
18.

Biodegradable cationic poly(carbonates): Effect of varying side chain hydrophobicity on key aspects of gene transfection.

Ong ZY, Yang C, Cheng W, Voo ZX, Chin W, Hedrick JL, Yang YY.

Acta Biomater. 2017 May;54:201-211. doi: 10.1016/j.actbio.2017.03.027. Epub 2017 Mar 18.

19.

Highly potent antimicrobial polyionenes with rapid killing kinetics, skin biocompatibility and in vivo bactericidal activity.

Liu S, Ono RJ, Wu H, Teo JY, Liang ZC, Xu K, Zhang M, Zhong G, Tan JP, Ng M, Yang C, Chan J, Ji Z, Bao C, Kumar K, Gao S, Lee A, Fevre M, Dong H, Ying JY, Li L, Fan W, Hedrick JL, Yang YY.

Biomaterials. 2017 May;127:36-48. doi: 10.1016/j.biomaterials.2017.02.027. Epub 2017 Feb 28.

PMID:
28279920
20.

Non-Isocyanate Polyurethane Soft Nanoparticles Obtained by Surfactant-Assisted Interfacial Polymerization.

Bossion A, Jones GO, Taton D, Mecerreyes D, Hedrick JL, Ong ZY, Yang YY, Sardon H.

Langmuir. 2017 Feb 28;33(8):1959-1968. doi: 10.1021/acs.langmuir.6b04242. Epub 2017 Feb 17.

PMID:
28118018
21.

Amphiphilic and Hydrophilic Block Copolymers from Aliphatic N-Substituted 8-Membered Cyclic Carbonates: A Versatile Macromolecular Platform for Biomedical Applications.

Venkataraman S, Tan JP, Ng VW, Tan EW, Hedrick JL, Yang YY.

Biomacromolecules. 2017 Jan 9;18(1):178-188. doi: 10.1021/acs.biomac.6b01463. Epub 2016 Dec 7.

PMID:
28064501
22.

Sialic acid-specific lectin participates in an immune response and ovarian development of the banana shrimp Fenneropenaeus merguiensis.

Utarabhand P, Rittidach W, Rattanaporn O, Runsaeng P, Hedrick JL.

Comp Biochem Physiol B Biochem Mol Biol. 2017 Jan;203:132-140. doi: 10.1016/j.cbpb.2016.10.005. Epub 2016 Oct 26.

PMID:
27793716
23.

Fast and selective ring-opening polymerizations by alkoxides and thioureas.

Zhang X, Jones GO, Hedrick JL, Waymouth RM.

Nat Chem. 2016 Nov;8(11):1047-1053. doi: 10.1038/nchem.2574. Epub 2016 Jul 25.

PMID:
27768102
24.

pH and redox dual-responsive biodegradable polymeric micelles with high drug loading for effective anticancer drug delivery.

Teo JY, Chin W, Ke X, Gao S, Liu S, Cheng W, Hedrick JL, Yang YY.

Nanomedicine. 2017 Feb;13(2):431-442. doi: 10.1016/j.nano.2016.09.016. Epub 2016 Oct 6.

PMID:
27720991
25.

Computational and experimental investigations of one-step conversion of poly(carbonate)s into value-added poly(aryl ether sulfone)s.

Jones GO, Yuen A, Wojtecki RJ, Hedrick JL, García JM.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7722-6. doi: 10.1073/pnas.1600924113. Epub 2016 Jun 27.

26.

Polyelemental nanoparticle libraries.

Chen PC, Liu X, Hedrick JL, Xie Z, Wang S, Lin QY, Hersam MC, Dravid VP, Mirkin CA.

Science. 2016 Jun 24;352(6293):1565-9. doi: 10.1126/science.aaf8402.

PMID:
27339985
27.

Tuning the Selectivity of Biodegradable Antimicrobial Cationic Polycarbonates by Exchanging the Counter-Anion.

Isik M, Tan JP, Ono RJ, Sanchez-Sanchez A, Mecerreyes D, Yang YY, Hedrick JL, Sardon H.

Macromol Biosci. 2016 Sep;16(9):1360-7. doi: 10.1002/mabi.201600090. Epub 2016 Jun 8.

PMID:
27273254
28.

Broad-Spectrum Antimicrobial Star Polycarbonates Functionalized with Mannose for Targeting Bacteria Residing inside Immune Cells.

Yang C, Krishnamurthy S, Liu J, Liu S, Lu X, Coady DJ, Cheng W, De Libero G, Singhal A, Hedrick JL, Yang YY.

Adv Healthc Mater. 2016 Jun;5(11):1272-81. doi: 10.1002/adhm.201600070. Epub 2016 Mar 29.

PMID:
27028263
29.

Hard Transparent Arrays for Polymer Pen Lithography.

Hedrick JL, Brown KA, Kluender EJ, Cabezas MD, Chen PC, Mirkin CA.

ACS Nano. 2016 Mar 22;10(3):3144-8. doi: 10.1021/acsnano.6b00528. Epub 2016 Mar 1.

30.

Co-delivery of drugs and plasmid DNA for cancer therapy.

Teo PY, Cheng W, Hedrick JL, Yang YY.

Adv Drug Deliv Rev. 2016 Mar 1;98:41-63. doi: 10.1016/j.addr.2015.10.014. Epub 2015 Oct 31. Review.

PMID:
26529199
31.

Developments in Dynamic Covalent Chemistries from the Reaction of Thiols with Hexahydrotriazines.

Wojtecki RJ, Jones GO, Yuen AY, Chin W, Boday DJ, Nelson A, García JM, Yang YY, Hedrick JL.

J Am Chem Soc. 2015 Nov 18;137(45):14248-51. doi: 10.1021/jacs.5b08815. Epub 2015 Nov 4.

PMID:
26505551
32.

A Simple and Facile Approach to Aliphatic N-Substituted Functional Eight-Membered Cyclic Carbonates and Their Organocatalytic Polymerization.

Venkataraman S, Ng VW, Coady DJ, Horn HW, Jones GO, Fung TS, Sardon H, Waymouth RM, Hedrick JL, Yang YY.

J Am Chem Soc. 2015 Nov 4;137(43):13851-60. doi: 10.1021/jacs.5b06355. Epub 2015 Oct 26.

PMID:
26456146
33.

Codelivery of dual drugs from polymeric micelles for simultaneous targeting of both cancer cells and cancer stem cells.

Krishnamurthy S, Ng VW, Gao S, Tan MH, Hedrick JL, Yang YY.

Nanomedicine (Lond). 2015;10(18):2819-32. doi: 10.2217/nnm.15.109. Epub 2015 Sep 7.

PMID:
26377155
34.

On-Tip Photo-Modulated Molecular Printing.

Xie Z, Zhou Y, Hedrick JL, Chen PC, He S, Shahjamali MM, Wang S, Zheng Z, Mirkin CA.

Angew Chem Int Ed Engl. 2015 Oct 26;54(44):12894-9. doi: 10.1002/anie.201505150. Epub 2015 Sep 9.

PMID:
26349629
35.

Biodegradable Antimicrobial Polycarbonates with In Vivo Efficacy against Multidrug-Resistant MRSA Systemic Infection.

Cheng J, Chin W, Dong H, Xu L, Zhong G, Huang Y, Li L, Xu K, Wu M, Hedrick JL, Yang YY, Fan W.

Adv Healthc Mater. 2015 Oct;4(14):2128-2136. doi: 10.1002/adhm.201500471. Epub 2015 Sep 1.

PMID:
26331284
36.

Thermoresponsive Random Poly(ether urethanes) with Tailorable LCSTs for Anticancer Drug Delivery.

Sardon H, Tan JP, Chan JM, Mantione D, Mecerreyes D, Hedrick JL, Yang YY.

Macromol Rapid Commun. 2015 Oct;36(19):1761-7. doi: 10.1002/marc.201500247. Epub 2015 Aug 11.

PMID:
26260576
37.

Melt-processable dynamic-covalent poly(hemiaminal) organogels as scaffolds for UV-induced polymerization.

Fevre M, Jones GO, Zhang M, García JM, Hedrick JL.

Adv Mater. 2015 Aug 26;27(32):4714-8. doi: 10.1002/adma.201502033. Epub 2015 Jul 15.

PMID:
26192764
38.

Supramolecular motifs in dynamic covalent PEG-hemiaminal organogels.

Fox CH, ter Hurrne GM, Wojtecki RJ, Jones GO, Horn HW, Meijer EW, Frank CW, Hedrick JL, García JM.

Nat Commun. 2015 Jul 15;6:7417. doi: 10.1038/ncomms8417.

39.

Tip-Directed Synthesis of Multimetallic Nanoparticles.

Chen PC, Liu G, Zhou Y, Brown KA, Chernyak N, Hedrick JL, He S, Xie Z, Lin QY, Dravid VP, O'Neill-Slawecki SA, Mirkin CA.

J Am Chem Soc. 2015 Jul 22;137(28):9167-73. doi: 10.1021/jacs.5b05139. Epub 2015 Jul 6.

PMID:
26144242
40.

Accurate Location and Manipulation of Nanoscaled Objects Buried under Spin-Coated Films.

Rawlings C, Wolf H, Hedrick JL, Coady DJ, Duerig U, Knoll AW.

ACS Nano. 2015 Jun 23;9(6):6188-95. doi: 10.1021/acsnano.5b01485. Epub 2015 Jun 11.

PMID:
26046586
41.

Broad-Spectrum Antimicrobial/Antifouling Soft Material Coatings Using Poly(ethylenimine) as a Tailorable Scaffold.

Cheng W, Yang C, Ding X, Engler AC, Hedrick JL, Yang YY.

Biomacromolecules. 2015 Jul 13;16(7):1967-77. doi: 10.1021/acs.biomac.5b00359. Epub 2015 Jun 17.

PMID:
26039032
42.

Development of a method for detecting trace metals in aqueous solutions based on the coordination chemistry of hexahydrotriazines.

Wojtecki RJ, Yuen AY, Zimmerman TG, Jones GO, Horn HW, Boday DJ, Hedrick JL, García JM.

Analyst. 2015 Aug 7;140(15):5184-9. doi: 10.1039/c5an00099h.

PMID:
26035633
43.

Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing.

Teo PY, Yang C, Whilding LM, Parente-Pereira AC, Maher J, George AJ, Hedrick JL, Yang YY, Ghaem-Maghami S.

Adv Healthc Mater. 2015 Jun 3;4(8):1180-9. doi: 10.1002/adhm.201500089. Epub 2015 Apr 11.

PMID:
25866054
44.

N-Heterocyclic Carbene-Catalyzed Ring Opening Polymerization of ε-Caprolactone with and without Alcohol Initiators: Insights from Theory and Experiment.

Jones GO, Chang YA, Horn HW, Acharya AK, Rice JE, Hedrick JL, Waymouth RM.

J Phys Chem B. 2015 Apr 30;119(17):5728-37. doi: 10.1021/acs.jpcb.5b01595. Epub 2015 Apr 16.

PMID:
25848823
45.

Structure-directing star-shaped block copolymers: supramolecular vesicles for the delivery of anticancer drugs.

Yang C, Liu SQ, Venkataraman S, Gao SJ, Ke X, Chia XT, Hedrick JL, Yang YY.

J Control Release. 2015 Jun 28;208:93-105. doi: 10.1016/j.jconrel.2015.03.027. Epub 2015 Mar 23.

PMID:
25813888
46.

Broad-spectrum antimicrobial polycarbonate hydrogels with fast degradability.

Pascual A, Tan JP, Yuen A, Chan JM, Coady DJ, Mecerreyes D, Hedrick JL, Yang YY, Sardon H.

Biomacromolecules. 2015 Apr 13;16(4):1169-78. doi: 10.1021/bm501836z. Epub 2015 Mar 26.

PMID:
25764341
47.

Injectable biodegradable hydrogels from vitamin D-functionalized polycarbonates for the delivery of avastin with enhanced therapeutic efficiency against metastatic colorectal cancer.

Lee AL, Ng VW, Gao S, Hedrick JL, Yang YY.

Biomacromolecules. 2015 Feb 9;16(2):465-75. doi: 10.1021/bm5015206. Epub 2015 Jan 16.

PMID:
25543531
48.

Antimicrobial hydrogels: a new weapon in the arsenal against multidrug-resistant infections.

Ng VW, Chan JM, Sardon H, Ono RJ, García JM, Yang YY, Hedrick JL.

Adv Drug Deliv Rev. 2014 Nov 30;78:46-62. doi: 10.1016/j.addr.2014.10.028. Review.

PMID:
25450263
49.

Computational and experimental studies on the mechanism of formation of poly(hexahydrotriazine)s and poly(hemiaminal)s from the reactions of amines with formaldehyde.

Jones GO, García JM, Horn HW, Hedrick JL.

Org Lett. 2014 Oct 17;16(20):5502-5. doi: 10.1021/ol502840k. Epub 2014 Oct 8.

PMID:
25295867
50.

Co-delivery of antiviral and antifungal therapeutics for the treatment of sexually transmitted infections using a moldable, supramolecular hydrogel.

Lee AL, Ng VW, Poon GL, Ke X, Hedrick JL, Yang YY.

Adv Healthc Mater. 2015 Feb 18;4(3):385-94. doi: 10.1002/adhm.201400340. Epub 2014 Sep 18.

PMID:
25234003

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