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Items: 1 to 50 of 67

1.

Regulatory Considerations on the Development, Evaluation, and Approval of Therapies in Rheumatoid Arthritis Prevention.

Richard C, Hedrick JA.

Clin Ther. 2019 Jul;41(7):1397-1400. doi: 10.1016/j.clinthera.2019.05.011. Epub 2019 Jun 12. No abstract available.

PMID:
31202507
2.

Agonists at GPR119 mediate secretion of GLP-1 from mouse enteroendocrine cells through glucose-independent pathways.

Lan H, Lin HV, Wang CF, Wright MJ, Xu S, Kang L, Juhl K, Hedrick JA, Kowalski TJ.

Br J Pharmacol. 2012 Apr;165(8):2799-807. doi: 10.1111/j.1476-5381.2011.01754.x.

3.

Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity.

Lan H, Cheng CC, Kowalski TJ, Pang L, Shan L, Chuang CC, Jackson J, Rojas-Triana A, Bober L, Liu L, Voigt J, Orth P, Yang X, Shipps GW Jr, Hedrick JA.

J Lipid Res. 2011 Apr;52(4):646-56. doi: 10.1194/jlr.M012757. Epub 2011 Feb 4.

4.

Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice.

Vassileva G, Hu W, Hoos L, Tetzloff G, Yang S, Liu L, Kang L, Davis HR, Hedrick JA, Lan H, Kowalski T, Gustafson EL.

J Endocrinol. 2010 Jun;205(3):225-32. doi: 10.1677/JOE-10-0009. Epub 2010 Mar 30.

PMID:
20354075
5.

Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects gene expression pathways beyond cholesterol metabolism in liver cells.

Lan H, Pang L, Smith MM, Levitan D, Ding W, Liu L, Shan L, Shah VV, Laverty M, Arreaza G, Zhang Q, Murgolo NJ, Hernandez M, Greene JR, Gustafson EL, Bayne ML, Davis HR, Hedrick JA.

J Cell Physiol. 2010 Jul;224(1):273-81. doi: 10.1002/jcp.22130.

PMID:
20333646
6.

Community-acquired upper respiratory tract infections and the role of third-generation oral cephalosporins.

Hedrick JA.

Expert Rev Anti Infect Ther. 2010 Jan;8(1):15-21. doi: 10.1586/eri.09.115.

PMID:
20014898
7.

Sustained efficacy and immunogenicity of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine: analysis of a randomised placebo-controlled trial up to 6.4 years.

GlaxoSmithKline Vaccine HPV-007 Study Group, Romanowski B, de Borba PC, Naud PS, Roteli-Martins CM, De Carvalho NS, Teixeira JC, Aoki F, Ramjattan B, Shier RM, Somani R, Barbier S, Blatter MM, Chambers C, Ferris D, Gall SA, Guerra FA, Harper DM, Hedrick JA, Henry DC, Korn AP, Kroll R, Moscicki AB, Rosenfeld WD, Sullivan BJ, Thoming CS, Tyring SK, Wheeler CM, Dubin G, Schuind A, Zahaf T, Greenacre M, Sgriobhadair A.

Lancet. 2009 Dec 12;374(9706):1975-85. doi: 10.1016/S0140-6736(09)61567-1.

PMID:
19962185
8.

Targeting PCSK9 for the treatment of hypercholesterolemia.

Hedrick JA.

Curr Opin Investig Drugs. 2009 Sep;10(9):938-46.

PMID:
19705336
9.

Safety of daily albuterol in infants with a history of bronchospasm: a multi-center placebo controlled trial.

Hedrick JA, Baker JW, Atlas AB, Naz AA, Lincourt WR, Trivedi R, Ellworth A, Davis AM.

Open Respir Med J. 2009 Jul 16;3:100-6. doi: 10.2174/1874306400903010100.

10.

GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis.

Lan H, Vassileva G, Corona A, Liu L, Baker H, Golovko A, Abbondanzo SJ, Hu W, Yang S, Ning Y, Del Vecchio RA, Poulet F, Laverty M, Gustafson EL, Hedrick JA, Kowalski TJ.

J Endocrinol. 2009 May;201(2):219-30. doi: 10.1677/JOE-08-0453. Epub 2009 Mar 12.

PMID:
19282326
11.

Nmur1-/- mice are not protected from cutaneous inflammation.

Abbondanzo SJ, Manfra DJ, Chen SC, Pinzon-Ortiz M, Sun Y, Phillips JE, Laverty M, Vassileva G, Hu W, Yang S, Gustafson EL, Fine JS, Hedrick JA.

Biochem Biophys Res Commun. 2009 Jan 23;378(4):777-82. doi: 10.1016/j.bbrc.2008.11.148. Epub 2008 Dec 12.

PMID:
19070594
12.

Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells.

Ning Y, O'Neill K, Lan H, Pang L, Shan LX, Hawes BE, Hedrick JA.

Br J Pharmacol. 2008 Dec;155(7):1056-65. doi: 10.1038/bjp.2008.337. Epub 2008 Aug 25.

13.

Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease.

Lan H, Hoos LM, Liu L, Tetzloff G, Hu W, Abbondanzo SJ, Vassileva G, Gustafson EL, Hedrick JA, Davis HR.

Diabetes. 2008 Nov;57(11):2999-3006. doi: 10.2337/db08-0596. Epub 2008 Aug 4.

14.

PCSK9 binds to multiple receptors and can be functionally inhibited by an EGF-A peptide.

Shan L, Pang L, Zhang R, Murgolo NJ, Lan H, Hedrick JA.

Biochem Biophys Res Commun. 2008 Oct 10;375(1):69-73. doi: 10.1016/j.bbrc.2008.07.106. Epub 2008 Jul 31.

PMID:
18675252
15.

A randomized comparative study of levofloxacin versus amoxicillin/clavulanate for treatment of infants and young children with recurrent or persistent acute otitis media.

Noel GJ, Blumer JL, Pichichero ME, Hedrick JA, Schwartz RH, Balis DA, Melkote R, Bagchi P, Arguedas A.

Pediatr Infect Dis J. 2008 Jun;27(6):483-9. doi: 10.1097/INF.0b013e318168d2cb.

PMID:
18449063
16.

P518/Qrfp sequence polymorphisms in SAMP6 osteopenic mouse.

Zhang Q, Qiu P, Arreaza MG, Simon JS, Golovko A, Laverty M, Vassileva G, Gustafson EL, Rojas-Triana A, Bober LA, Hedrick JA, Monsma FJ Jr, Greene JR, Bayne ML, Murgolo NJ.

Genomics. 2007 Nov;90(5):629-35. Epub 2007 Sep 17.

17.

Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial.

Paavonen J, Jenkins D, Bosch FX, Naud P, Salmerón J, Wheeler CM, Chow SN, Apter DL, Kitchener HC, Castellsague X, de Carvalho NS, Skinner SR, Harper DM, Hedrick JA, Jaisamrarn U, Limson GA, Dionne M, Quint W, Spiessens B, Peeters P, Struyf F, Wieting SL, Lehtinen MO, Dubin G; HPV PATRICIA study group.

Lancet. 2007 Jun 30;369(9580):2161-2170. doi: 10.1016/S0140-6736(07)60946-5. Erratum in: Lancet. 2007 Oct 20;370(9596):1414.

PMID:
17602732
18.

Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8.

Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, Manfra DJ, Vassileva G, Zeng M, Jackson C, Sullivan L, Sharif-Rodriguez W, Opdenakker G, Van Damme J, Hedrick JA, Lundell D, Lira SA, Hipkin RW.

J Biol Chem. 2007 Apr 20;282(16):11658-66. Epub 2006 Dec 29.

19.

Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice.

Kowalski TJ, Spar BD, Markowitz L, Maguire M, Golovko A, Yang S, Farley C, Cook JA, Tetzloff G, Hoos L, Del Vecchio RA, Kazdoba TM, McCool MF, Hwa JJ, Hyde LA, Davis H, Vassileva G, Hedrick JA, Gustafson EL.

J Endocrinol. 2005 Apr;185(1):151-64.

PMID:
15817836
20.

Treatment options in the management of uncomplicated skin and skin structure infections.

Scher RK, Elston DM, Hedrick JA, Joseph WS, Maurer T, Murakawa GJ.

Cutis. 2005 Jan;75(1 Suppl):3-23. Review. No abstract available.

PMID:
15732428
21.

The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system.

Funes S, Hedrick JA, Vassileva G, Markowitz L, Abbondanzo S, Golovko A, Yang S, Monsma FJ, Gustafson EL.

Biochem Biophys Res Commun. 2003 Dec 26;312(4):1357-63.

PMID:
14652023
22.

PepPat, a pattern-based oligopeptide homology search method and the identification of a novel tachykinin-like peptide.

Jiang Y, Gao G, Fang G, Gustafson EL, Laverty M, Yin Y, Zhang Y, Luo J, Greene JR, Bayne ML, Hedrick JA, Murgolo NJ.

Mamm Genome. 2003 May;14(5):341-9. Erratum in: Mamm Genome. 2003 Aug;14(8):580.

PMID:
12856286
23.

Centrally administered hemokinin-1 (HK-1), a neurokinin NK1 receptor agonist, produces substance P-like behavioral effects in mice and gerbils.

Duffy RA, Hedrick JA, Randolph G, Morgan CA, Cohen-Williams ME, Vassileva G, Lachowicz JE, Laverty M, Maguire M, Shan LS, Gustafson E, Varty GB.

Neuropharmacology. 2003 Aug;45(2):242-50.

PMID:
12842130
24.

A reference database for tumor-related genes co-expressed with interleukin-8 using genome-scale in silico analysis.

Benbow L, Wang L, Laverty M, Liu S, Qiu P, Bond RW, Gustafson E, Hedrick JA, Kostich M, Greene JR, Wang L.

BMC Genomics. 2002 Oct 11;3(1):29.

25.

Cloning and characterization of murine neuromedin U receptors.

Funes S, Hedrick JA, Yang S, Shan L, Bayne M, Monsma FJ Jr, Gustafson EL.

Peptides. 2002 Sep;23(9):1607-15.

PMID:
12217421
26.

Disruption of neutrophil migration in a conditional transgenic model: evidence for CXCR2 desensitization in vivo.

Wiekowski MT, Chen SC, Zalamea P, Wilburn BP, Kinsley DJ, Sharif WW, Jensen KK, Hedrick JA, Manfra D, Lira SA.

J Immunol. 2001 Dec 15;167(12):7102-10.

27.

Microbiology of acute otitis media recently treated with aminopenicillins.

Block SL, Hedrick JA, Tyler RD, Smith RA, Harrison CJ.

Pediatr Infect Dis J. 2001 Nov;20(11):1017-21.

PMID:
11734704
28.

Cefprozil versus high-dose amoxicillin/clavulanate in children with acute otitis media.

Hedrick JA, Sher LD, Schwartz RH, Pierce P.

Clin Ther. 2001 Feb;23(2):193-204.

PMID:
11293553
29.

Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice.

Chensue SW, Lukacs NW, Yang TY, Shang X, Frait KA, Kunkel SL, Kung T, Wiekowski MT, Hedrick JA, Cook DN, Zingoni A, Narula SK, Zlotnik A, Barrat FJ, O'Garra A, Napolitano M, Lira SA.

J Exp Med. 2001 Mar 5;193(5):573-84.

30.

Cloning and characterization of a novel human histamine receptor.

Morse KL, Behan J, Laz TM, West RE Jr, Greenfeder SA, Anthes JC, Umland S, Wan Y, Hipkin RW, Gonsiorek W, Shin N, Gustafson EL, Qiao X, Wang S, Hedrick JA, Greene J, Bayne M, Monsma FJ Jr.

J Pharmacol Exp Ther. 2001 Mar;296(3):1058-66.

PMID:
11181941
31.

Comparative safety and efficacy of cefdinir vs amoxicillin/clavulanate for treatment of suppurative acute otitis media in children.

Block SL, McCarty JM, Hedrick JA, Nemeth MA, Keyserling CH, Tack KJ; Cefdinir Otitis Media Study Group.

Pediatr Infect Dis J. 2000 Dec;19(12 Suppl):S159-65.

PMID:
11144398
32.

Five-day twice daily cefdinir therapy for acute otitis media: microbiologic and clinical efficacy.

Block SL, Hedrick JA, Kratzer J, Nemeth MA, Tack KJ.

Pediatr Infect Dis J. 2000 Dec;19(12 Suppl):S153-8.

PMID:
11144397
33.

Identification of a novel neuromedin U receptor subtype expressed in the central nervous system.

Shan L, Qiao X, Crona JH, Behan J, Wang S, Laz T, Bayne M, Gustafson EL, Monsma FJ Jr, Hedrick JA.

J Biol Chem. 2000 Dec 15;275(50):39482-6.

34.

Identification of a human gastrointestinal tract and immune system receptor for the peptide neuromedin U.

Hedrick JA, Morse K, Shan L, Qiao X, Pang L, Wang S, Laz T, Gustafson EL, Bayne M, Monsma FJ Jr.

Mol Pharmacol. 2000 Oct;58(4):870-5.

PMID:
10999960
35.

Clarithromycin suspension vs penicillin V suspension in children with streptococcal pharyngitis.

McCarty J, Hedrick JA, Gooch WM.

Adv Ther. 2000 Jan-Feb;17(1):14-26.

PMID:
10915400
36.

Zanamivir for treatment of symptomatic influenza A and B infection in children five to twelve years of age: a randomized controlled trial.

Hedrick JA, Barzilai A, Behre U, Henderson FW, Hammond J, Reilly L, Keene O.

Pediatr Infect Dis J. 2000 May;19(5):410-7.

PMID:
10819336
37.

Identification of viral macrophage inflammatory protein (vMIP)-II as a ligand for GPR5/XCR1.

Shan L, Qiao X, Oldham E, Catron D, Kaminski H, Lundell D, Zlotnik A, Gustafson E, Hedrick JA.

Biochem Biophys Res Commun. 2000 Feb 24;268(3):938-41.

PMID:
10679309
38.

Chemokines and chemokine receptors in T-cell development.

Hedrick JA, Zlotnik A.

Chem Immunol. 1999;72:57-68. Review. No abstract available.

PMID:
10550930
39.

The assignment of chemokine-chemokine receptor pairs: TARC and MIP-1 beta are not ligands for human CC-chemokine receptor 8.

Garlisi CG, Xiao H, Tian F, Hedrick JA, Billah MM, Egan RW, Umland SP.

Eur J Immunol. 1999 Oct;29(10):3210-5.

40.

The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes.

Vassileva G, Soto H, Zlotnik A, Nakano H, Kakiuchi T, Hedrick JA, Lira SA.

J Exp Med. 1999 Oct 18;190(8):1183-8.

41.
42.

Recent advances in chemokines and chemokine receptors.

Zlotnik A, Morales J, Hedrick JA.

Crit Rev Immunol. 1999;19(1):1-47. Review.

PMID:
9987599
43.

Lymphotactin acts as an innate mucosal adjuvant.

Lillard JW Jr, Boyaka PN, Hedrick JA, Zlotnik A, McGhee JR.

J Immunol. 1999 Feb 15;162(4):1959-65.

44.
45.

The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells.

Zingoni A, Soto H, Hedrick JA, Stoppacciaro A, Storlazzi CT, Sinigaglia F, D'Ambrosio D, O'Garra A, Robinson D, Rocchi M, Santoni A, Zlotnik A, Napolitano M.

J Immunol. 1998 Jul 15;161(2):547-51.

46.

Lymphotactin.

Hedrick JA, Zlotnik A.

Clin Immunol Immunopathol. 1998 Jun;87(3):218-22. Review. No abstract available.

PMID:
9646830
47.

Characterization of a novel CC chemokine, HCC-4, whose expression is increased by interleukin-10.

Hedrick JA, Helms A, Vicari A, Zlotnik A.

Blood. 1998 Jun 1;91(11):4242-7.

PMID:
9596672
48.
49.

TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.

Vicari AP, Figueroa DJ, Hedrick JA, Foster JS, Singh KP, Menon S, Copeland NG, Gilbert DJ, Jenkins NA, Bacon KB, Zlotnik A.

Immunity. 1997 Aug;7(2):291-301.

50.

Middle ear effusion concentrations of cefixime during acute otitis media with effusion and otitis media with effusion.

Harrison CJ, Chartrand SA, Rodriguez W, Schwartz R, Pollack J, Thedinger B, Block SL, Hedrick JA.

Pediatr Infect Dis J. 1997 Aug;16(8):816-7. No abstract available.

PMID:
9271047

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