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Items: 1 to 50 of 394

1.

Rapid, large-volume, thermally controlled 3D printing using a mobile liquid interface.

Walker DA, Hedrick JL, Mirkin CA.

Science. 2019 Oct 18;366(6463):360-364. doi: 10.1126/science.aax1562.

PMID:
31624211
2.

Voriconazole-Induced Periostitis.

Hedrick J, Droz N.

N Engl J Med. 2019 Oct 10;381(15):e30. doi: 10.1056/NEJMicm1814565. No abstract available.

PMID:
31597023
3.

Subcutaneous vaccination using injectable biodegradable hydrogels for long-term immune response.

Lee ALZ, Yang C, Gao S, Hedrick JL, Yang YY.

Nanomedicine. 2019 Oct;21:102056. doi: 10.1016/j.nano.2019.102056. Epub 2019 Jul 20.

PMID:
31336176
4.

Regulatory Considerations on the Development, Evaluation, and Approval of Therapies in Rheumatoid Arthritis Prevention.

Richard C, Hedrick JA.

Clin Ther. 2019 Jul;41(7):1397-1400. doi: 10.1016/j.clinthera.2019.05.011. Epub 2019 Jun 12. No abstract available.

PMID:
31202507
5.

Degradable antimicrobial polycarbonates with unexpected activity and selectivity for treating multidrug-resistant Klebsiella pneumoniae lung infection in mice.

Yang C, Lou W, Zhong G, Lee A, Leong J, Chin W, Ding B, Bao C, Tan JPK, Pu Q, Gao S, Xu L, Hsu LY, Wu M, Hedrick JL, Fan W, Yang YY.

Acta Biomater. 2019 Aug;94:268-280. doi: 10.1016/j.actbio.2019.05.057. Epub 2019 May 24.

PMID:
31129359
6.

Programmable High-Throughput Platform for the Rapid and Scalable Synthesis of Polyester and Polycarbonate Libraries.

Lin B, Hedrick JL, Park NH, Waymouth RM.

J Am Chem Soc. 2019 Jun 5;141(22):8921-8927. doi: 10.1021/jacs.9b02450. Epub 2019 May 22.

PMID:
31117549
7.

ELP1 Splicing Correction Reverses Proprioceptive Sensory Loss in Familial Dysautonomia.

Morini E, Gao D, Montgomery CM, Salani M, Mazzasette C, Krussig TA, Swain B, Dietrich P, Narasimhan J, Gabbeta V, Dakka A, Hedrick J, Zhao X, Weetall M, Naryshkin NA, Wojtkiewicz GG, Ko CP, Talkowski ME, Dragatsis I, Slaugenhaupt SA.

Am J Hum Genet. 2019 Apr 4;104(4):638-650. doi: 10.1016/j.ajhg.2019.02.009. Epub 2019 Mar 21.

8.

Polymers with distinctive anticancer mechanism that kills MDR cancer cells and inhibits tumor metastasis.

Zhong G, Yang C, Liu S, Zheng Y, Lou W, Teo JY, Bao C, Cheng W, Tan JPK, Gao S, Park N, Venkataraman S, Huang Y, Tan MH, Wang X, Hedrick JL, Fan W, Yang YY.

Biomaterials. 2019 Apr;199:76-87. doi: 10.1016/j.biomaterials.2019.01.036. Epub 2019 Jan 25.

PMID:
30771551
9.

Effective encapsulation of apomorphine into biodegradable polymeric nanoparticles through a reversible chemical bond for delivery across the blood-brain barrier.

Tan JPK, Voo ZX, Lim S, Venkataraman S, Ng KM, Gao S, Hedrick JL, Yang YY.

Nanomedicine. 2019 Apr;17:236-245. doi: 10.1016/j.nano.2019.01.014. Epub 2019 Feb 6.

PMID:
30738234
10.

Persistence of bactericidal antibodies 4 years after a booster dose of quadrivalent meningococcal diphtheria toxoid conjugate vaccine (MenACWY-D).

Robertson CA, Hedrick J, Bassily E, Greenberg DP.

Vaccine. 2019 Feb 14;37(8):1016-1020. doi: 10.1016/j.vaccine.2019.01.008. Epub 2019 Jan 19.

11.

Nanocombinatorics with Cantilever-Free Scanning Probe Arrays.

Brown KA, Hedrick JL, Eichelsdoerfer DJ, Mirkin CA.

ACS Nano. 2019 Jan 22;13(1):8-17. doi: 10.1021/acsnano.8b08185. Epub 2018 Dec 18.

PMID:
30561191
12.

Catalyst discovery through megalibraries of nanomaterials.

Kluender EJ, Hedrick JL, Brown KA, Rao R, Meckes B, Du JS, Moreau LM, Maruyama B, Mirkin CA.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):40-45. doi: 10.1073/pnas.1815358116. Epub 2018 Dec 17.

13.

Hydrogels with prolonged release of therapeutic antibody: Block junction chemistry modification of 'ABA' copolymers provides superior anticancer efficacy.

Yang C, Lee A, Gao S, Liu S, Hedrick JL, Yang YY.

J Control Release. 2019 Jan 10;293:193-200. doi: 10.1016/j.jconrel.2018.11.026. Epub 2018 Dec 4.

PMID:
30521830
14.

The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.

Friesen WJ, Johnson B, Sierra J, Zhuo J, Vazirani P, Xue X, Tomizawa Y, Baiazitov R, Morrill C, Ren H, Babu S, Moon YC, Branstrom A, Mollin A, Hedrick J, Sheedy J, Elfring G, Weetall M, Colacino JM, Welch EM, Peltz SW.

PLoS One. 2018 Oct 25;13(10):e0206158. doi: 10.1371/journal.pone.0206158. eCollection 2018.

15.

Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties.

Cao L, Weetall M, Trotta C, Cintron K, Ma J, Kim MJ, Furia B, Romfo C, Graci JD, Li W, Du J, Sheedy J, Hedrick J, Risher N, Yeh S, Qi H, Arasu T, Hwang S, Lennox W, Kong R, Petruska J, Moon YC, Babiak J, Davis TW, Jacobson A, Almstead NG, Branstrom A, Colacino JM, Peltz SW.

Mol Cancer Ther. 2019 Jan;18(1):3-16. doi: 10.1158/1535-7163.MCT-18-0863. Epub 2018 Oct 23.

PMID:
30352802
16.

Disease-directed design of biodegradable polymers: Reactive oxygen species and pH-responsive micellar nanoparticles for anticancer drug delivery.

Leong J, Chin W, Ke X, Gao S, Kong H, Hedrick JL, Yang YY.

Nanomedicine. 2018 Nov;14(8):2666-2677. doi: 10.1016/j.nano.2018.06.015. Epub 2018 Jul 12.

PMID:
30017961
17.

Dual pH-Responsive Shell-Cleavable Polycarbonate Micellar Nanoparticles for in Vivo Anticancer Drug Delivery.

Liu S, Ono RJ, Yang C, Gao S, Ming Tan JY, Hedrick JL, Yang YY.

ACS Appl Mater Interfaces. 2018 Jun 13;10(23):19355-19364. doi: 10.1021/acsami.8b01954. Epub 2018 May 29.

PMID:
29757607
18.

Injectable Coacervate Hydrogel for Delivery of Anticancer Drug-Loaded Nanoparticles in vivo.

Lee ALZ, Voo ZX, Chin W, Ono RJ, Yang C, Gao S, Hedrick JL, Yang YY.

ACS Appl Mater Interfaces. 2018 Apr 25;10(16):13274-13282. doi: 10.1021/acsami.7b14319. Epub 2018 Apr 16.

PMID:
29595244
19.

Addressing Drug Resistance in Cancer with Macromolecular Chemotherapeutic Agents.

Park NH, Cheng W, Lai F, Yang C, Florez de Sessions P, Periaswamy B, Wenhan Chu C, Bianco S, Liu S, Venkataraman S, Chen Q, Yang YY, Hedrick JL.

J Am Chem Soc. 2018 Mar 28;140(12):4244-4252. doi: 10.1021/jacs.7b11468. Epub 2018 Mar 15.

PMID:
29504396
20.

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset.

Chin W, Zhong G, Pu Q, Yang C, Lou W, De Sessions PF, Periaswamy B, Lee A, Liang ZC, Ding X, Gao S, Chu CW, Bianco S, Bao C, Tong YW, Fan W, Wu M, Hedrick JL, Yang YY.

Nat Commun. 2018 Mar 2;9(1):917. doi: 10.1038/s41467-018-03325-6.

21.

Peptide-Functionalized Polyurethane Coatings Prepared via Grafting-To Strategy to Selectively Promote Endothelialization.

Ding X, Chin W, Lee CN, Hedrick JL, Yang YY.

Adv Healthc Mater. 2018 Mar;7(5). doi: 10.1002/adhm.201700944. Epub 2017 Dec 4.

PMID:
29205938
22.

Erratum: Organocatalyzed synthesis of fluorinated poly(aryl thioethers).

Park NH, Gomes GDP, Fevre M, Jones GO, Alabugin IV, Hedrick JL.

Nat Commun. 2017 Nov 13;8(1):1553. doi: 10.1038/s41467-017-01129-8.

23.

4-Hydroxy-2-pyridones: Discovery and evaluation of a novel class of antibacterial agents targeting DNA synthesis.

Arnold MA, Gerasyuto AI, Wang J, Du W, Gorske YJK, Arasu T, Baird J, Almstead NG, Narasimhan J, Peddi S, Ginzburg O, Lue SW, Hedrick J, Sheedy J, Lagaud G, Branstrom AA, Weetall M, Prasad JVNV, Karp GM.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):5014-5021. doi: 10.1016/j.bmcl.2017.10.006. Epub 2017 Oct 5.

PMID:
29032026
24.

Supramolecular nanofibers self-assembled from cationic small molecules derived from repurposed poly(ethylene teraphthalate) for antibiotic delivery.

Liu S, Fukushima K, Venkataraman S, Hedrick JL, Yang YY.

Nanomedicine. 2018 Jan;14(1):165-172. doi: 10.1016/j.nano.2017.09.007. Epub 2017 Sep 30.

PMID:
28974393
25.

Organocatalyzed synthesis of fluorinated poly(aryl thioethers).

Park NH, Gomes GDP, Fevre M, Jones GO, Alabugin IV, Hedrick JL.

Nat Commun. 2017 Aug 1;8(1):166. doi: 10.1038/s41467-017-00186-3. Erratum in: Nat Commun. 2017 Nov 13;8(1):1553.

26.

Structural Evolution of Three-Component Nanoparticles in Polymer Nanoreactors.

Chen PC, Du JS, Meckes B, Huang L, Xie Z, Hedrick JL, Dravid VP, Mirkin CA.

J Am Chem Soc. 2017 Jul 26;139(29):9876-9884. doi: 10.1021/jacs.7b03163. Epub 2017 Jul 12.

PMID:
28700228
27.

Biodegradable Strain-Promoted Click Hydrogels for Encapsulation of Drug-Loaded Nanoparticles and Sustained Release of Therapeutics.

Ono RJ, Lee ALZ, Voo ZX, Venkataraman S, Koh BW, Yang YY, Hedrick JL.

Biomacromolecules. 2017 Aug 14;18(8):2277-2285. doi: 10.1021/acs.biomac.7b00377. Epub 2017 Jul 21.

PMID:
28682629
28.

Broad Spectrum Macromolecular Antimicrobials with Biofilm Disruption Capability and In Vivo Efficacy.

Tan JPK, Coady DJ, Sardon H, Yuen A, Gao S, Lim SW, Liang ZC, Tan EW, Venkataraman S, Engler AC, Fevre M, Ono R, Yang YY, Hedrick JL.

Adv Healthc Mater. 2017 Aug;6(16). doi: 10.1002/adhm.201601420. Epub 2017 May 15.

PMID:
28504348
29.

Biodegradable cationic poly(carbonates): Effect of varying side chain hydrophobicity on key aspects of gene transfection.

Ong ZY, Yang C, Cheng W, Voo ZX, Chin W, Hedrick JL, Yang YY.

Acta Biomater. 2017 May;54:201-211. doi: 10.1016/j.actbio.2017.03.027. Epub 2017 Mar 18.

30.

Highly potent antimicrobial polyionenes with rapid killing kinetics, skin biocompatibility and in vivo bactericidal activity.

Liu S, Ono RJ, Wu H, Teo JY, Liang ZC, Xu K, Zhang M, Zhong G, Tan JP, Ng M, Yang C, Chan J, Ji Z, Bao C, Kumar K, Gao S, Lee A, Fevre M, Dong H, Ying JY, Li L, Fan W, Hedrick JL, Yang YY.

Biomaterials. 2017 May;127:36-48. doi: 10.1016/j.biomaterials.2017.02.027. Epub 2017 Feb 28.

PMID:
28279920
31.

Non-Isocyanate Polyurethane Soft Nanoparticles Obtained by Surfactant-Assisted Interfacial Polymerization.

Bossion A, Jones GO, Taton D, Mecerreyes D, Hedrick JL, Ong ZY, Yang YY, Sardon H.

Langmuir. 2017 Feb 28;33(8):1959-1968. doi: 10.1021/acs.langmuir.6b04242. Epub 2017 Feb 17.

PMID:
28118018
32.

The nucleoside analog clitocine is a potent and efficacious readthrough agent.

Friesen WJ, Trotta CR, Tomizawa Y, Zhuo J, Johnson B, Sierra J, Roy B, Weetall M, Hedrick J, Sheedy J, Takasugi J, Moon YC, Babu S, Baiazitov R, Leszyk JD, Davis TW, Colacino JM, Peltz SW, Welch EM.

RNA. 2017 Apr;23(4):567-577. doi: 10.1261/rna.060236.116. Epub 2017 Jan 17.

33.

Amphiphilic and Hydrophilic Block Copolymers from Aliphatic N-Substituted 8-Membered Cyclic Carbonates: A Versatile Macromolecular Platform for Biomedical Applications.

Venkataraman S, Tan JP, Ng VW, Tan EW, Hedrick JL, Yang YY.

Biomacromolecules. 2017 Jan 9;18(1):178-188. doi: 10.1021/acs.biomac.6b01463. Epub 2016 Dec 7.

PMID:
28064501
34.

Discovery of Novel Small Molecule Inhibitors of VEGF Expression in Tumor Cells Using a Cell-Based High Throughput Screening Platform.

Cao L, Weetall M, Bombard J, Qi H, Arasu T, Lennox W, Hedrick J, Sheedy J, Risher N, Brooks PC, Trifillis P, Trotta C, Moon YC, Babiak J, Almstead NG, Colacino JM, Davis TW, Peltz SW.

PLoS One. 2016 Dec 16;11(12):e0168366. doi: 10.1371/journal.pone.0168366. eCollection 2016.

35.

Sialic acid-specific lectin participates in an immune response and ovarian development of the banana shrimp Fenneropenaeus merguiensis.

Utarabhand P, Rittidach W, Rattanaporn O, Runsaeng P, Hedrick JL.

Comp Biochem Physiol B Biochem Mol Biol. 2017 Jan;203:132-140. doi: 10.1016/j.cbpb.2016.10.005. Epub 2016 Oct 26.

PMID:
27793716
36.

Fast and selective ring-opening polymerizations by alkoxides and thioureas.

Zhang X, Jones GO, Hedrick JL, Waymouth RM.

Nat Chem. 2016 Nov;8(11):1047-1053. doi: 10.1038/nchem.2574. Epub 2016 Jul 25.

PMID:
27768102
37.

pH and redox dual-responsive biodegradable polymeric micelles with high drug loading for effective anticancer drug delivery.

Teo JY, Chin W, Ke X, Gao S, Liu S, Cheng W, Hedrick JL, Yang YY.

Nanomedicine. 2017 Feb;13(2):431-442. doi: 10.1016/j.nano.2016.09.016. Epub 2016 Oct 6.

PMID:
27720991
38.

Safety and immunogenicity of a booster dose of meningococcal (groups A, C, W, and Y) polysaccharide diphtheria toxoid conjugate vaccine.

Robertson CA, Greenberg DP, Hedrick J, Pichichero M, Decker MD, Saunders M.

Vaccine. 2016 Oct 17;34(44):5273-5278. doi: 10.1016/j.vaccine.2016.09.003. Epub 2016 Sep 15.

39.

Prior human papillomavirus-16/18 AS04-adjuvanted vaccination prevents recurrent high grade cervical intraepithelial neoplasia after definitive surgical therapy: Post-hoc analysis from a randomized controlled trial.

Garland SM, Paavonen J, Jaisamrarn U, Naud P, Salmerón J, Chow SN, Apter D, Castellsagué X, Teixeira JC, Skinner SR, Hedrick J, Limson G, Schwarz TF, Poppe WA, Bosch FX, de Carvalho NS, Germar MJ, Peters K, Del Rosario-Raymundo MR, Catteau G, Descamps D, Struyf F, Lehtinen M, Dubin G; HPV PATRICIA Study Group.

Int J Cancer. 2016 Dec 15;139(12):2812-2826. doi: 10.1002/ijc.30391. Epub 2016 Sep 9.

40.

Computational and experimental investigations of one-step conversion of poly(carbonate)s into value-added poly(aryl ether sulfone)s.

Jones GO, Yuen A, Wojtecki RJ, Hedrick JL, García JM.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7722-6. doi: 10.1073/pnas.1600924113. Epub 2016 Jun 27.

41.

Polyelemental nanoparticle libraries.

Chen PC, Liu X, Hedrick JL, Xie Z, Wang S, Lin QY, Hersam MC, Dravid VP, Mirkin CA.

Science. 2016 Jun 24;352(6293):1565-9. doi: 10.1126/science.aaf8402.

PMID:
27339985
42.

Tuning the Selectivity of Biodegradable Antimicrobial Cationic Polycarbonates by Exchanging the Counter-Anion.

Isik M, Tan JP, Ono RJ, Sanchez-Sanchez A, Mecerreyes D, Yang YY, Hedrick JL, Sardon H.

Macromol Biosci. 2016 Sep;16(9):1360-7. doi: 10.1002/mabi.201600090. Epub 2016 Jun 8.

PMID:
27273254
43.

Broad-Spectrum Antimicrobial Star Polycarbonates Functionalized with Mannose for Targeting Bacteria Residing inside Immune Cells.

Yang C, Krishnamurthy S, Liu J, Liu S, Lu X, Coady DJ, Cheng W, De Libero G, Singhal A, Hedrick JL, Yang YY.

Adv Healthc Mater. 2016 Jun;5(11):1272-81. doi: 10.1002/adhm.201600070. Epub 2016 Mar 29.

PMID:
27028263
44.

Hard Transparent Arrays for Polymer Pen Lithography.

Hedrick JL, Brown KA, Kluender EJ, Cabezas MD, Chen PC, Mirkin CA.

ACS Nano. 2016 Mar 22;10(3):3144-8. doi: 10.1021/acsnano.6b00528. Epub 2016 Mar 1.

45.

Co-delivery of drugs and plasmid DNA for cancer therapy.

Teo PY, Cheng W, Hedrick JL, Yang YY.

Adv Drug Deliv Rev. 2016 Mar 1;98:41-63. doi: 10.1016/j.addr.2015.10.014. Epub 2015 Oct 31. Review.

PMID:
26529199
46.

Developments in Dynamic Covalent Chemistries from the Reaction of Thiols with Hexahydrotriazines.

Wojtecki RJ, Jones GO, Yuen AY, Chin W, Boday DJ, Nelson A, García JM, Yang YY, Hedrick JL.

J Am Chem Soc. 2015 Nov 18;137(45):14248-51. doi: 10.1021/jacs.5b08815. Epub 2015 Nov 4.

PMID:
26505551
47.

A Simple and Facile Approach to Aliphatic N-Substituted Functional Eight-Membered Cyclic Carbonates and Their Organocatalytic Polymerization.

Venkataraman S, Ng VW, Coady DJ, Horn HW, Jones GO, Fung TS, Sardon H, Waymouth RM, Hedrick JL, Yang YY.

J Am Chem Soc. 2015 Nov 4;137(43):13851-60. doi: 10.1021/jacs.5b06355. Epub 2015 Oct 26.

PMID:
26456146
48.

Codelivery of dual drugs from polymeric micelles for simultaneous targeting of both cancer cells and cancer stem cells.

Krishnamurthy S, Ng VW, Gao S, Tan MH, Hedrick JL, Yang YY.

Nanomedicine (Lond). 2015;10(18):2819-32. doi: 10.2217/nnm.15.109. Epub 2015 Sep 7.

PMID:
26377155
49.

On-Tip Photo-Modulated Molecular Printing.

Xie Z, Zhou Y, Hedrick JL, Chen PC, He S, Shahjamali MM, Wang S, Zheng Z, Mirkin CA.

Angew Chem Int Ed Engl. 2015 Oct 26;54(44):12894-9. doi: 10.1002/anie.201505150. Epub 2015 Sep 9.

PMID:
26349629
50.

Biodegradable Antimicrobial Polycarbonates with In Vivo Efficacy against Multidrug-Resistant MRSA Systemic Infection.

Cheng J, Chin W, Dong H, Xu L, Zhong G, Huang Y, Li L, Xu K, Wu M, Hedrick JL, Yang YY, Fan W.

Adv Healthc Mater. 2015 Oct;4(14):2128-2136. doi: 10.1002/adhm.201500471. Epub 2015 Sep 1.

PMID:
26331284

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