Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 97


Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry.

Hamers AAJ, Dinh HQ, Thomas GD, Marcovecchio P, Blatchley A, Nakao CS, Kim C, McSkimming C, Taylor AM, Nguyen AT, McNamara CA, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2019 Jan;39(1):25-36. doi: 10.1161/ATVBAHA.118.311022.


Neutrophils: New insights and open questions.

Ley K, Hoffman HM, Kubes P, Cassatella MA, Zychlinsky A, Hedrick CC, Catz SD.

Sci Immunol. 2018 Dec 7;3(30). pii: eaat4579. doi: 10.1126/sciimmunol.aat4579. Epub 2018 Dec 7. Review.


Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow.

Zhu YP, Padgett L, Dinh HQ, Marcovecchio P, Blatchley A, Wu R, Ehinger E, Kim C, Mikulski Z, Seumois G, Madrigal A, Vijayanand P, Hedrick CC.

Cell Rep. 2018 Aug 28;24(9):2329-2341.e8. doi: 10.1016/j.celrep.2018.07.097.


Publisher Correction: Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL.

Nature. 2018 Sep;561(7724):E43. doi: 10.1038/s41586-018-0313-x.


Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice.

Que X, Hung MY, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Määttä A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Ylä-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL.

Nature. 2018 Jun;558(7709):301-306. doi: 10.1038/s41586-018-0198-8. Epub 2018 Jun 6. Erratum in: Nature. 2018 Sep;561(7724):E43.


Understanding the tumor immune microenvironment (TIME) for effective therapy.

Binnewies M, Roberts EW, Kersten K, Chan V, Fearon DF, Merad M, Coussens LM, Gabrilovich DI, Ostrand-Rosenberg S, Hedrick CC, Vonderheide RH, Pittet MJ, Jain RK, Zou W, Howcroft TK, Woodhouse EC, Weinberg RA, Krummel MF.

Nat Med. 2018 May;24(5):541-550. doi: 10.1038/s41591-018-0014-x. Epub 2018 Apr 23. Review.


Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis.

Gaddis DE, Padgett LE, Wu R, McSkimming C, Romines V, Taylor AM, McNamara CA, Kronenberg M, Crotty S, Thomas MJ, Sorci-Thomas MG, Hedrick CC.

Nat Commun. 2018 Mar 15;9(1):1095. doi: 10.1038/s41467-018-03493-5.


Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.

Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh HQ, Kobiyama K, Hamers AAJ, Cochain C, Vafadarnejad E, Saliba AE, Zernecke A, Pramod AB, Ghosh AK, Anto Michel N, Hoppe N, Hilgendorf I, Zirlik A, Hedrick CC, Ley K, Wolf D.

Circ Res. 2018 Jun 8;122(12):1675-1688. doi: 10.1161/CIRCRESAHA.117.312513. Epub 2018 Mar 15.


Patrolling Mechanics of Non-Classical Monocytes in Vascular Inflammation.

Buscher K, Marcovecchio P, Hedrick CC, Ley K.

Front Cardiovasc Med. 2017 Dec 19;4:80. doi: 10.3389/fcvm.2017.00080. eCollection 2017. Review.


Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis.

Marcovecchio PM, Thomas GD, Mikulski Z, Ehinger E, Mueller KAL, Blatchley A, Wu R, Miller YI, Nguyen AT, Taylor AM, McNamara CA, Ley K, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2043-2052. doi: 10.1161/ATVBAHA.117.309123. Epub 2017 Sep 21.


Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry.

Thomas GD, Hamers AAJ, Nakao C, Marcovecchio P, Taylor AM, McSkimming C, Nguyen AT, McNamara CA, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1548-1558. doi: 10.1161/ATVBAHA.117.309145. Epub 2017 Jun 8.


Hematopoietic stem cells gone rogue.

Zhu YP, Hedrick CC, Gaddis DE.

Science. 2017 Feb 24;355(6327):798-799. doi: 10.1126/science.aam7939. No abstract available.


ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content.

Nowyhed HN, Chandra S, Kiosses W, Marcovecchio P, Andary F, Zhao M, Fitzgerald ML, Kronenberg M, Hedrick CC.

Sci Rep. 2017 Jan 16;7:40273. doi: 10.1038/srep40273.


The transcription factor NR4A3 controls CD103+ dendritic cell migration.

Park K, Mikulski Z, Seo GY, Andreyev AY, Marcovecchio P, Blatchley A, Kronenberg M, Hedrick CC.

J Clin Invest. 2016 Dec 1;126(12):4603-4615. doi: 10.1172/JCI87081. Epub 2016 Nov 7.


Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function.

Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC.

Immunity. 2016 Nov 15;45(5):975-987. doi: 10.1016/j.immuni.2016.10.011. Epub 2016 Nov 1.


Update on Gender Equity in Immunology, 2001 to 2016.

Shapiro VS, Kovats S, Parent MA, Gaffen SL, Hedrick CC, Jain P, Denzin LK, Raghavan M, Stephens R.

J Immunol. 2016 Nov 15;197(10):3751-3753. Epub 2016 Oct 17.


Quantification of Tumor Material Uptake.

Hanna RN, Hedrick CC.

Bio Protoc. 2016 Oct 20;6(20). pii: e1974. doi: 10.21769/BioProtoc.1974.


In vivo Imaging of Tumor and Immune Cell Interactions in the Lung.

Hanna RN, Chodaczek G, Hedrick CC.

Bio Protoc. 2016 Oct 20;6(20). pii: e1973. doi: 10.21769/BioProtoc.1973.


ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells.

Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV.

J Clin Invest. 2016 Oct 3;126(10):3905-3916. doi: 10.1172/JCI85329. Epub 2016 Sep 12.


Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.

Cheng HY, Gaddis DE, Wu R, McSkimming C, Haynes LD, Taylor AM, McNamara CA, Sorci-Thomas M, Hedrick CC.

J Clin Invest. 2016 Sep 1;126(9):3236-46. doi: 10.1172/JCI83136. Epub 2016 Aug 2.


2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.

Zhu YP, Thomas GD, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1722-33. doi: 10.1161/ATVBAHA.116.304054. Epub 2016 Jul 7. Review.


Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.

Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC.

Nat Immunol. 2015 Dec;16(12):1228-34. doi: 10.1038/ni.3321. Epub 2015 Nov 2.


Patrolling monocytes control tumor metastasis to the lung.

Hanna RN, Cekic C, Sag D, Tacke R, Thomas GD, Nowyhed H, Herrley E, Rasquinha N, McArdle S, Wu R, Peluso E, Metzger D, Ichinose H, Shaked I, Chodaczek G, Biswas SK, Hedrick CC.

Science. 2015 Nov 20;350(6263):985-90. doi: 10.1126/science.aac9407. Epub 2015 Oct 22.


Cutting Edge: The Orphan Nuclear Receptor Nr4a1 Regulates CD8+ T Cell Expansion and Effector Function through Direct Repression of Irf4.

Nowyhed HN, Huynh TR, Thomas GD, Blatchley A, Hedrick CC.

J Immunol. 2015 Oct 15;195(8):3515-9. doi: 10.4049/jimmunol.1403027. Epub 2015 Sep 11.


Cardif (MAVS) Regulates the Maturation of NK Cells.

Haynes LD, Verma S, McDonald B, Wu R, Tacke R, Nowyhed HN, Ekstein J, Feuvrier A, Benedict CA, Hedrick CC.

J Immunol. 2015 Sep 1;195(5):2157-67. doi: 10.4049/jimmunol.1402060. Epub 2015 Jul 31.


The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus.

Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, Hanna RN, Wu R, Swirski FK, Geissmann F, Hedrick CC.

Sci Rep. 2015 Jun 19;5:10055. doi: 10.1038/srep10055.


Monocyte phenotypes: when local education counts.

Quintar AA, Hedrick CC, Ley K.

J Exp Med. 2015 Apr 6;212(4):432. doi: 10.1084/jem.2124insight1. Review. No abstract available.


Nonclassical patrolling monocyte function in the vasculature.

Thomas G, Tacke R, Hedrick CC, Hanna RN.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1306-16. doi: 10.1161/ATVBAHA.114.304650. Epub 2015 Apr 2. Review.


The nuclear receptor nr4a1 controls CD8 T cell development through transcriptional suppression of runx3.

Nowyhed HN, Huynh TR, Blatchley A, Wu R, Thomas GD, Hedrick CC.

Sci Rep. 2015 Mar 12;5:9059. doi: 10.1038/srep09059.


The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.

Sag D, Cekic C, Wu R, Linden J, Hedrick CC.

Nat Commun. 2015 Feb 27;6:6354. doi: 10.1038/ncomms7354.


Lymphocytes in atherosclerosis.

Hedrick CC.

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):253-7. doi: 10.1161/ATVBAHA.114.305144. Review. No abstract available.


IL-10-producing NKT10 cells are a distinct regulatory invariant NKT cell subset.

Sag D, Krause P, Hedrick CC, Kronenberg M, Wingender G.

J Clin Invest. 2014 Sep;124(9):3725-40. doi: 10.1172/JCI72308. Epub 2014 Jul 25.


Stressing out stem cells: linking stress and hematopoiesis in cardiovascular disease.

Hanna RN, Hedrick CC.

Nat Med. 2014 Jul;20(7):707-8. doi: 10.1038/nm.3631. No abstract available.


Gammadelta (γδ) T lymphocytes do not impact the development of early atherosclerosis.

Cheng HY, Wu R, Hedrick CC.

Atherosclerosis. 2014 Jun;234(2):265-9. doi: 10.1016/j.atherosclerosis.2014.03.007. Epub 2014 Mar 20.


Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium.

Hilgendorf I, Gerhardt LM, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK.

Circ Res. 2014 May 9;114(10):1611-22. doi: 10.1161/CIRCRESAHA.114.303204. Epub 2014 Mar 13.


NR4A nuclear receptors in immunity and atherosclerosis.

Hamers AA, Hanna RN, Nowyhed H, Hedrick CC, de Vries CJ.

Curr Opin Lipidol. 2013 Oct;24(5):381-5. doi: 10.1097/MOL.0b013e3283643eac.


Myeloid cells in atherosclerosis: a delicate balance of anti-inflammatory and proinflammatory mechanisms.

Koltsova EK, Hedrick CC, Ley K.

Curr Opin Lipidol. 2013 Oct;24(5):371-80. doi: 10.1097/MOL.0b013e328363d298. Review.


Increased cholesterol content in gammadelta (γδ) T lymphocytes differentially regulates their activation.

Cheng HY, Wu R, Gebre AK, Hanna RN, Smith DJ, Parks JS, Ley K, Hedrick CC.

PLoS One. 2013 May 21;8(5):e63746. doi: 10.1371/journal.pone.0063746. Print 2013.


Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal.

Carlin LM, Stamatiades EG, Auffray C, Hanna RN, Glover L, Vizcay-Barrena G, Hedrick CC, Cook HT, Diebold S, Geissmann F.

Cell. 2013 Apr 11;153(2):362-75. doi: 10.1016/j.cell.2013.03.010.


Molecular imaging of the paracrine proangiogenic effects of progenitor cell therapy in limb ischemia.

Ryu JC, Davidson BP, Xie A, Qi Y, Zha D, Belcik JT, Caplan ES, Woda JM, Hedrick CC, Hanna RN, Lehman N, Zhao Y, Ting A, Lindner JR.

Circulation. 2013 Feb 12;127(6):710-9. doi: 10.1161/CIRCULATIONAHA.112.116103. Epub 2013 Jan 10.


ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development.

Sag D, Wingender G, Nowyhed H, Wu R, Gebre AK, Parks JS, Kronenberg M, Hedrick CC.

J Immunol. 2012 Dec 1;189(11):5129-38. doi: 10.4049/jimmunol.1201570. Epub 2012 Oct 24.


Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1.

Galkina EV, Butcher M, Keller SR, Goff M, Bruce A, Pei H, Sarembock IJ, Sanders JM, Nagelin MH, Srinivasan S, Kulkarni RN, Hedrick CC, Lattanzio FA, Dobrian AD, Nadler JL, Ley K.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):247-56. doi: 10.1161/ATVBAHA.111.240358. Epub 2011 Dec 22.


NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis.

Hanna RN, Shaked I, Hubbeling HG, Punt JA, Wu R, Herrley E, Zaugg C, Pei H, Geissmann F, Ley K, Hedrick CC.

Circ Res. 2012 Feb 3;110(3):416-27. doi: 10.1161/CIRCRESAHA.111.253377. Epub 2011 Dec 22.


The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes.

Hanna RN, Carlin LM, Hubbeling HG, Nackiewicz D, Green AM, Punt JA, Geissmann F, Hedrick CC.

Nat Immunol. 2011 Jul 3;12(8):778-85. doi: 10.1038/ni.2063.


Monocyte and macrophage dynamics during atherogenesis.

Ley K, Miller YI, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1506-16. doi: 10.1161/ATVBAHA.110.221127. Review.


Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans.

Figler RA, Wang G, Srinivasan S, Jung DY, Zhang Z, Pankow JS, Ravid K, Fredholm B, Hedrick CC, Rich SS, Kim JK, LaNoue KF, Linden J.

Diabetes. 2011 Feb;60(2):669-79. doi: 10.2337/db10-1070.


Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.

Burdon KP, Rudock ME, Lehtinen AB, Langefeld CD, Bowden DW, Register TC, Liu Y, Freedman BI, Carr JJ, Hedrick CC, Rich SS.

Mediators Inflamm. 2010;2010:170153. doi: 10.1155/2010/170153. Epub 2010 May 31.


An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells.

Sturek JM, Castle JD, Trace AP, Page LC, Castle AM, Evans-Molina C, Parks JS, Mirmira RG, Hedrick CC.

J Clin Invest. 2010 Jul;120(7):2575-89. doi: 10.1172/JCI41280. Epub 2010 Jun 7.


ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions.

Whetzel AM, Sturek JM, Nagelin MH, Bolick DT, Gebre AK, Parks JS, Bruce AC, Skaflen MD, Hedrick CC.

Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):809-17. doi: 10.1161/ATVBAHA.109.199166. Epub 2010 Jan 28.


ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.

Armstrong AJ, Gebre AK, Parks JS, Hedrick CC.

J Immunol. 2010 Jan 1;184(1):173-83. doi: 10.4049/jimmunol.0902372. Epub 2009 Nov 30.

Supplemental Content

Loading ...
Support Center