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Penicillin V four times daily for five days versus three times daily for 10 days in patients with pharyngotonsillitis caused by group A streptococci: randomised controlled, open label, non-inferiority study.

Skoog Ståhlgren G, Tyrstrup M, Edlund C, Giske CG, Mölstad S, Norman C, Rystedt K, Sundvall PD, Hedin K.

BMJ. 2019 Oct 4;367:l5337. doi: 10.1136/bmj.l5337.


Increased adherence to treatment guidelines in patients with urinary tract infection in primary care: A retrospective study.

Kornfält Isberg H, Hedin K, Melander E, Mölstad S, Beckman A.

PLoS One. 2019 Mar 28;14(3):e0214572. doi: 10.1371/journal.pone.0214572. eCollection 2019.


Uncomplicated urinary tract infections in Swedish primary care; etiology, resistance and treatment.

Kornfält Isberg H, Melander E, Hedin K, Mölstad S, Beckman A.

BMC Infect Dis. 2019 Feb 13;19(1):155. doi: 10.1186/s12879-019-3785-x.


GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts.

Sterner RM, Sakemura R, Cox MJ, Yang N, Khadka RH, Forsman CL, Hansen MJ, Jin F, Ayasoufi K, Hefazi M, Schick KJ, Walters DK, Ahmed O, Chappell D, Sahmoud T, Durrant C, Nevala WK, Patnaik MM, Pease LR, Hedin KE, Kay NE, Johnson AJ, Kenderian SS.

Blood. 2019 Feb 14;133(7):697-709. doi: 10.1182/blood-2018-10-881722. Epub 2018 Nov 21.


GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion.

Dinkel BA, Kremer KN, Rollins MR, Medlyn MJ, Hedin KE.

J Biol Chem. 2018 Sep 7;293(36):14022-14039. doi: 10.1074/jbc.RA118.003097. Epub 2018 Jul 17.


Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis.

Sterner RM, Kremer KN, Dudakovic A, Westendorf JJ, van Wijnen AJ, Hedin KE.

J Immunol. 2018 Aug 1;201(3):1086-1096. doi: 10.4049/jimmunol.1800174. Epub 2018 Jun 18.


Treatment of depression and/or anxiety - outcomes of a randomised controlled trial of the tree theme method® versus regular occupational therapy.

Birgitta Gunnarsson A, Wagman P, Hedin K, Håkansson C.

BMC Psychol. 2018 May 23;6(1):25. doi: 10.1186/s40359-018-0237-0.


Comparison of antibiotic prescribing and antimicrobial resistance in urinary tract infections at the municipal level among women in two Nordic regions.

Nygaard Jensen J, Melander E, Hedin K, Bjerrum L, Kornfält Isberg H, Holm A, Neel Jacobsen H, Skovby A, Córdoba Currea GC, Hyllebusk L, Brogaard E, Arpi M.

J Antimicrob Chemother. 2018 Aug 1;73(8):2207-2214. doi: 10.1093/jac/dky177.


A 2-year follow-up study of patients with pharyngotonsillitis.

Pallon J, Sundqvist M, Hedin K.

BMC Infect Dis. 2018 Jan 2;18(1):3. doi: 10.1186/s12879-017-2917-4.


Histone deacetylase inhibitors reduce differentiating osteoblast-mediated protection of acute myeloid leukemia cells from cytarabine.

Sterner RM, Kremer KN, Al-Kali A, Patnaik MM, Gangat N, Litzow MR, Kaufmann SH, Westendorf JJ, van Wijnen AJ, Hedin KE.

Oncotarget. 2017 Oct 10;8(55):94569-94579. doi: 10.18632/oncotarget.21809. eCollection 2017 Nov 7.


Lessons learnt during 20 years of the Swedish strategic programme against antibiotic resistance.

Mölstad S, Löfmark S, Carlin K, Erntell M, Aspevall O, Blad L, Hanberger H, Hedin K, Hellman J, Norman C, Skoog G, Stålsby-Lundborg C, Tegmark Wisell K, Åhrén C, Cars O.

Bull World Health Organ. 2017 Nov 1;95(11):764-773. doi: 10.2471/BLT.16.184374. Epub 2017 Oct 3.


TCR-CXCR4 signaling stabilizes cytokine mRNA transcripts via a PREX1-Rac1 pathway: implications for CTCL.

Kremer KN, Dinkel BA, Sterner RM, Osborne DG, Jevremovic D, Hedin KE.

Blood. 2017 Aug 24;130(8):982-994. doi: 10.1182/blood-2017-03-770982. Epub 2017 Jul 10.


Reduction in antibiotic prescribing for respiratory tract infections in Swedish primary care- a retrospective study of electronic patient records.

Tyrstrup M, Beckman A, Mölstad S, Engström S, Lannering C, Melander E, Hedin K.

BMC Infect Dis. 2016 Nov 25;16(1):709.


A randomized controlled study of 5 and 10 days treatment with phenoxymethylpenicillin for pharyngotonsillitis caused by streptococcus group A - a protocol study.

Skoog G, Edlund C, Giske CG, Mölstad S, Norman C, Sundvall PD, Hedin K.

BMC Infect Dis. 2016 Sep 13;16:484. doi: 10.1186/s12879-016-1813-7.


Interacting factors associated with Low antibiotic prescribing for respiratory tract infections in primary health care - a mixed methods study in Sweden.

Strandberg EL, Brorsson A, André M, Gröndal H, Mölstad S, Hedin K.

BMC Fam Pract. 2016 Jul 18;17:78. doi: 10.1186/s12875-016-0494-z.


Uncertainty in clinical practice - an interview study with Swedish GPs on patients with sore throat.

Andre M, Gröndal H, Strandberg EL, Brorsson A, Hedin K.

BMC Fam Pract. 2016 May 18;17:56. doi: 10.1186/s12875-016-0452-9.


PD-1 Blunts the Function of Ovarian Tumor-Infiltrating Dendritic Cells by Inactivating NF-κB.

Karyampudi L, Lamichhane P, Krempski J, Kalli KR, Behrens MD, Vargas DM, Hartmann LC, Janco JM, Dong H, Hedin KE, Dietz AB, Goode EL, Knutson KL.

Cancer Res. 2016 Jan 15;76(2):239-50. doi: 10.1158/0008-5472.CAN-15-0748. Epub 2015 Nov 13.


The Tree Theme Method® (TTM), an occupational therapy intervention for treating depression and anxiety: study protocol of a randomized controlled trial.

Gunnarsson AB, Wagman P, Håkansson C, Hedin K.

BMC Psychol. 2015 Nov 9;3:40. doi: 10.1186/s40359-015-0097-9.


Histone Deacetylase Inhibitors Target the Leukemic Microenvironment by Enhancing a Nherf1-Protein Phosphatase 1α-TAZ Signaling Pathway in Osteoblasts.

Kremer KN, Dudakovic A, Hess AD, Smith BD, Karp JE, Kaufmann SH, Westendorf JJ, van Wijnen AJ, Hedin KE.

J Biol Chem. 2015 Dec 4;290(49):29478-92. doi: 10.1074/jbc.M115.668160. Epub 2015 Oct 21.

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