Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 86

1.

An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed Guinea pigs.

Pirttilä K, Videhult Pierre P, Haglöf J, Engskog M, Hedeland M, Laurell G, Arvidsson T, Pettersson C.

Metabolomics. 2019 Oct 5;15(10):138. doi: 10.1007/s11306-019-1595-1.

2.

Exploring Radiation Response in Two Head and Neck Squamous Carcinoma Cell Lines Through Metabolic Profiling.

Lindell Jonsson E, Erngren I, Engskog M, Haglöf J, Arvidsson T, Hedeland M, Petterson C, Laurell G, Nestor M.

Front Oncol. 2019 Aug 30;9:825. doi: 10.3389/fonc.2019.00825. eCollection 2019.

3.

Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions.

Roos C, Dahlgren D, Sjögren E, Sjöblom M, Hedeland M, Lennernäs H.

Eur J Pharm Biopharm. 2019 Sep;142:387-395. doi: 10.1016/j.ejpb.2019.07.012. Epub 2019 Jul 12.

PMID:
31306752
4.

Disposition and effect of intra-articularly administered dexamethasone on lipopolysaccharide induced equine synovitis.

Ekstrand C, Bondesson U, Giving E, Hedeland M, Ingvast-Larsson C, Jacobsen S, Löfgren M, Moen L, Rhodin M, Saetra T, Ranheim B.

Acta Vet Scand. 2019 Jun 20;61(1):28. doi: 10.1186/s13028-019-0464-2.

5.

Adduct formation in electrospray ionisation-mass spectrometry with hydrophilic interaction liquid chromatography is strongly affected by the inorganic ion concentration of the samples.

Erngren I, Haglöf J, Engskog MKR, Nestor M, Hedeland M, Arvidsson T, Pettersson C.

J Chromatogr A. 2019 Aug 30;1600:174-182. doi: 10.1016/j.chroma.2019.04.049. Epub 2019 Apr 19.

PMID:
31047661
6.

Common Fatty Markers in Diseases with Dysregulated Lipogenesis.

Balgoma D, Pettersson C, Hedeland M.

Trends Endocrinol Metab. 2019 May;30(5):283-285. doi: 10.1016/j.tem.2019.02.008. Epub 2019 Mar 26.

PMID:
30926249
7.

Cetirizine per os: exposure and antihistamine effect in the dog.

Ekstrand C, Ingvast-Larsson C, Bondesson U, Hedeland M, Olsén L.

Acta Vet Scand. 2018 Nov 26;60(1):77. doi: 10.1186/s13028-018-0431-3.

8.

Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer.

Roos C, Dahlgren D, Sjögren E, Sjöblom M, Hedeland M, Lennernäs H.

Eur J Pharm Biopharm. 2018 Nov;132:222-230. doi: 10.1016/j.ejpb.2018.09.022. Epub 2018 Sep 25.

PMID:
30266667
9.

Effects of Oral Supplementation With Nitrate-Rich Beetroot Juice in Patients With Pulmonary Arterial Hypertension-Results From BEET-PAH, an Exploratory Randomized, Double-Blind, Placebo-Controlled, Crossover Study.

Henrohn D, Björkstrand K, Lundberg JO, Granstam SO, Baron T, Ingimarsdóttir IJ, Hedenström H, Malinovschi A, Wernroth ML, Jansson M, Hedeland M, Wikström G.

J Card Fail. 2018 Oct;24(10):640-653. doi: 10.1016/j.cardfail.2018.09.010. Epub 2018 Sep 20.

PMID:
30244181
10.

Alterations in plasma L-arginine and methylarginines in heart failure and after heart transplantation.

Lundgren J, Sandqvist A, Hedeland M, Bondesson U, Wikström G, Rådegran G.

Scand Cardiovasc J. 2018 Aug;52(4):196-204. doi: 10.1080/14017431.2018.1459823. Epub 2018 Apr 12.

PMID:
29648475
11.

Major signal suppression from metal ion clusters in SFC/ESI-MS - Cause and effects.

Haglind A, Hedeland M, Arvidsson T, Pettersson CE.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 May 1;1084:96-105. doi: 10.1016/j.jchromb.2018.03.024. Epub 2018 Mar 19.

PMID:
29579734
12.

Removal of diclofenac from a non-sterile aqueous system using Trametes versicolor with an emphasis on adsorption and biodegradation mechanisms.

Stenholm Å, Hedeland M, Arvidsson T, Pettersson CE.

Environ Technol. 2019 Aug;40(19):2460-2472. doi: 10.1080/09593330.2018.1444098. Epub 2018 Mar 4.

PMID:
29464996
13.

Equine in vivo-derived metabolites of the SARM LGD-4033 and comparison with human and fungal metabolites.

Hansson A, Knych H, Stanley S, Berndtson E, Jackson L, Bondesson U, Thevis M, Hedeland M.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 1;1074-1075:91-98. doi: 10.1016/j.jchromb.2017.12.010. Epub 2017 Dec 7.

PMID:
29334634
14.

Structural elucidation of major selective androgen receptor modulator (SARM) metabolites for doping control.

Garg N, Hansson A, Knych HK, Stanley SD, Thevis M, Bondesson U, Hedeland M, Globisch D.

Org Biomol Chem. 2018 Jan 31;16(5):698-702. doi: 10.1039/c7ob03030d.

PMID:
29319101
15.

The differences in matrix effect between supercritical fluid chromatography and reversed phase liquid chromatography coupled to ESI/MS.

Svan A, Hedeland M, Arvidsson T, Pettersson CE.

Anal Chim Acta. 2018 Feb 13;1000:163-171. doi: 10.1016/j.aca.2017.10.014. Epub 2017 Oct 23.

PMID:
29289305
16.

Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'".

Dubbelboer IR, Lilienberg E, Karalli A, Axelsson R, Brismar TB, Ebeling Barbier C, Norén A, Duraj F, Hedeland M, Bondesson U, Sjögren E, Stål P, Nyman R, Lennernäs H.

Mol Pharm. 2018 Jan 2;15(1):336-340. doi: 10.1021/acs.molpharmaceut.7b00840. Epub 2017 Dec 1. No abstract available.

PMID:
29185767
17.

Plasma L-arginine levels distinguish pulmonary arterial hypertension from left ventricular systolic dysfunction.

Sandqvist A, Schneede J, Kylhammar D, Henrohn D, Lundgren J, Hedeland M, Bondesson U, Rådegran G, Wikström G.

Heart Vessels. 2018 Mar;33(3):255-263. doi: 10.1007/s00380-017-1055-7. Epub 2017 Oct 3.

18.

Quantification of dimethylsulfoxide (DMSO) in equine plasma and urine using HILIC-MS/MS.

Salomonsson ML, Bondesson U, Hedeland M.

Drug Test Anal. 2017 Sep;9(9):1472. doi: 10.1002/dta.2265. Epub 2017 Aug 30. No abstract available.

PMID:
28945329
19.

Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses.

Knych HK, Stanley SD, McKemie DS, Arthur RM, Bondesson U, Hedeland M, Thevis M, Kass PH.

Drug Test Anal. 2017 Sep;9(9):1392-1399. doi: 10.1002/dta.2214. Epub 2017 Aug 1.

PMID:
28513092
20.

Antitumoral effect and reduced systemic toxicity in mice after intra-tumoral injection of an in vivo solidifying calcium sulfate formulation with docetaxel.

Grudén S, Sandelin M, Rasanen V, Micke P, Hedeland M, Axén N, Jeansson M.

Eur J Pharm Biopharm. 2017 May;114:186-193. doi: 10.1016/j.ejpb.2017.01.018. Epub 2017 Feb 1.

PMID:
28161551
21.

In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma.

Lilienberg E, Dubbelboer IR, Karalli A, Axelsson R, Brismar TB, Ebeling Barbier C, Norén A, Duraj F, Hedeland M, Bondesson U, Sjögren E, Stål P, Nyman R, Lennernäs H.

Mol Pharm. 2017 Feb 6;14(2):448-458. doi: 10.1021/acs.molpharmaceut.6b00886. Epub 2017 Jan 5.

PMID:
27997198
22.

Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry.

Hansson A, Thevis M, Cox H, Miller G, Eichner D, Bondesson U, Hedeland M.

J Pharm Biomed Anal. 2017 Feb 5;134:228-236. doi: 10.1016/j.jpba.2016.11.041. Epub 2016 Nov 27.

PMID:
27918992
23.

Quantification of dimethylsulfoxide (DMSO) in equine plasma and urine using HILIC-MS/MS.

Salomonsson ML, Bondesson U, Hedeland M.

Drug Test Anal. 2017 Jun;9(6):935-941. doi: 10.1002/dta.2098. Epub 2016 Nov 4. Erratum in: Drug Test Anal. 2017 Sep;9(9):1472.

PMID:
27670954
24.

Nickel in equine sports drug testing - pilot study results on urinary nickel concentrations.

Thevis M, Machnik M, Schenk I, Krug O, Piper T, Schänzer W, Düe M, Bondesson U, Hedeland M.

Rapid Commun Mass Spectrom. 2016 Apr 15;30(7):982-4. doi: 10.1002/rcm.7528.

PMID:
26969941
25.

Investigation of the selective androgen receptor modulators S1, S4 and S22 and their metabolites in equine plasma using high-resolution mass spectrometry.

Hansson A, Knych H, Stanley S, Thevis M, Bondesson U, Hedeland M.

Rapid Commun Mass Spectrom. 2016 Apr 15;30(7):833-42. doi: 10.1002/rcm.7512.

PMID:
26969924
26.

Identification of transformation products from β-blocking agents formed in wetland microcosms using LC-Q-ToF.

Svan A, Hedeland M, Arvidsson T, Jasper JT, Sedlak DL, Pettersson CE.

J Mass Spectrom. 2016 Mar;51(3):207-18. doi: 10.1002/jms.3737.

PMID:
26956388
27.

Fully automated determination of nicotine and its major metabolites in whole blood by means of a DBS online-SPE LC-HR-MS/MS approach for sports drug testing.

Tretzel L, Thomas A, Piper T, Hedeland M, Geyer H, Schänzer W, Thevis M.

J Pharm Biomed Anal. 2016 May 10;123:132-40. doi: 10.1016/j.jpba.2016.02.009. Epub 2016 Feb 10.

PMID:
26896632
28.

Seafood sold in Sweden contains BMAA: A study of free and total concentrations with UHPLC-MS/MS and dansyl chloride derivatization.

Salomonsson ML, Fredriksson E, Alfjorden A, Hedeland M, Bondesson U.

Toxicol Rep. 2015 Nov 15;2:1473-1481. doi: 10.1016/j.toxrep.2015.11.002. eCollection 2015.

29.

A quantitative approach to analysing cortisol response in the horse.

Ekstrand C, Ingvast-Larsson C, Olsén L, Hedeland M, Bondesson U, Gabrielsson J.

J Vet Pharmacol Ther. 2016 Jun;39(3):255-63. doi: 10.1111/jvp.12276. Epub 2015 Nov 6.

PMID:
26542753
30.

Acute vasodilator response to vardenafil and clinical outcome in patients with pulmonary hypertension.

Sandqvist A, Henrohn D, Egeröd H, Hedeland M, Wernroth L, Bondesson U, Schneede J, Wikström G.

Eur J Clin Pharmacol. 2015 Oct;71(10):1165-73. doi: 10.1007/s00228-015-1914-z. Epub 2015 Aug 5.

PMID:
26242227
31.

Rapid chiral separation of atenolol, metoprolol, propranolol and the zwitterionic metoprolol acid using supercritical fluid chromatography-tandem mass spectrometry - Application to wetland microcosms.

Svan A, Hedeland M, Arvidsson T, Jasper JT, Sedlak DL, Pettersson CE.

J Chromatogr A. 2015 Aug 28;1409:251-8. doi: 10.1016/j.chroma.2015.07.075. Epub 2015 Jul 21.

PMID:
26228849
32.

Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification of in vitro generated phase-I metabolites for human sports drug testing.

Thevis M, Lagojda A, Kuehne D, Thomas A, Dib J, Hansson A, Hedeland M, Bondesson U, Wigger T, Karst U, Schänzer W.

Rapid Commun Mass Spectrom. 2015 Jun 15;29(11):991-9. doi: 10.1002/rcm.7189.

PMID:
26044265
33.

Changes in plasma levels of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine after a single dose of vardenafil in patients with pulmonary hypertension.

Henrohn D, Sandqvist A, Egeröd H, Hedeland M, Wernroth L, Bondesson U, Wikström G.

Vascul Pharmacol. 2015 Oct;73:71-7. doi: 10.1016/j.vph.2015.04.010. Epub 2015 Apr 29.

PMID:
25934511
34.

Characterization of equine urinary metabolites of selective androgen receptor modulators (SARMs) S1, S4 and S22 for doping control purposes.

Hansson A, Knych H, Stanley S, Thevis M, Bondesson U, Hedeland M.

Drug Test Anal. 2015 Aug;7(8):673-83. doi: 10.1002/dta.1768. Epub 2015 Jan 5.

PMID:
25560998
35.

Plasma concentration-dependent suppression of endogenous hydrocortisone in the horse after intramuscular administration of dexamethasone-21-isonicotinate.

Ekstrand C, Bondesson U, Gabrielsson J, Hedeland M, Kallings P, Olsén L, Ingvast-Larsson C.

J Vet Pharmacol Ther. 2015 Jun;38(3):235-42. doi: 10.1111/jvp.12175. Epub 2014 Nov 3.

PMID:
25366540
36.

Validation of the Endopep-MS method for qualitative detection of active botulinum neurotoxins in human and chicken serum.

Björnstad K, Tevell Åberg A, Kalb SR, Wang D, Barr JR, Bondesson U, Hedeland M.

Anal Bioanal Chem. 2014 Nov;406(28):7149-61. doi: 10.1007/s00216-014-8170-4. Epub 2014 Sep 17.

37.

A novel trapping system for the detection of reactive drug metabolites using the fungus Cunninghamella elegans and high resolution mass spectrometry.

Rydevik A, Hansson A, Hellqvist A, Bondesson U, Hedeland M.

Drug Test Anal. 2015 Jul;7(7):626-33. doi: 10.1002/dta.1714. Epub 2014 Sep 10.

PMID:
25209992
38.

Isolation and characterization of a β-glucuronide of hydroxylated SARM S1 produced using a combination of biotransformation and chemical oxidation.

Rydevik A, Lagojda A, Thevis M, Bondesson U, Hedeland M.

J Pharm Biomed Anal. 2014 Sep;98:36-9. doi: 10.1016/j.jpba.2014.05.001. Epub 2014 May 9.

PMID:
24879518
39.

The effects of lipiodol and cyclosporin A on the hepatobiliary disposition of doxorubicin in pigs.

Dubbelboer IR, Lilienberg E, Hedeland M, Bondesson U, Piquette-Miller M, Sjögren E, Lennernäs H.

Mol Pharm. 2014 Apr 7;11(4):1301-13. doi: 10.1021/mp4007612. Epub 2014 Mar 7.

PMID:
24558959
40.

High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile.

Lundahl A, Tevell Åberg A, Bondesson U, Lennernäs H, Hedeland M.

Xenobiotica. 2014 Jun;44(6):498-510. doi: 10.3109/00498254.2013.866298. Epub 2013 Dec 9.

PMID:
24320817
41.

Mass spectrometric detection of protein-based toxins.

Tevell Åberg A, Björnstad K, Hedeland M.

Biosecur Bioterror. 2013 Sep;11 Suppl 1:S215-26. doi: 10.1089/bsp.2012.0072. Review.

PMID:
23971809
42.

Management of animal botulism outbreaks: from clinical suspicion to practical countermeasures to prevent or minimize outbreaks.

Anniballi F, Fiore A, Löfström C, Skarin H, Auricchio B, Woudstra C, Bano L, Segerman B, Koene M, Båverud V, Hansen T, Fach P, Tevell Aberg A, Hedeland M, Olsson Engvall E, De Medici D.

Biosecur Bioterror. 2013 Sep;11 Suppl 1:S191-9. doi: 10.1089/bsp.2012.0089.

PMID:
23971806
43.

The workshop on animal botulism in Europe.

Skarin H, Tevell Åberg A, Woudstra C, Hansen T, Löfström C, Koene M, Bano L, Hedeland M, Anniballi F, De Medici D, Olsson Engvall E.

Biosecur Bioterror. 2013 Sep;11 Suppl 1:S183-90. doi: 10.1089/bsp.2012.0076.

PMID:
23971805
44.

Animal botulism outcomes in the AniBioThreat project.

Woudstra C, Tevell Åberg A, Skarin H, Anniballi F, De Medici D, Bano L, Koene M, Löfström C, Hansen T, Hedeland M, Fach P.

Biosecur Bioterror. 2013 Sep;11 Suppl 1:S177-82. doi: 10.1089/bsp.2012.0074.

PMID:
23971804
45.

Investigation of hepatobiliary disposition of doxorubicin following intrahepatic delivery of different dosage forms.

Lilienberg E, Ebeling Barbier C, Nyman R, Hedeland M, Bondesson U, Axén N, Lennernäs H.

Mol Pharm. 2014 Jan 6;11(1):131-44. doi: 10.1021/mp4002574. Epub 2013 Nov 21.

PMID:
24171458
46.

Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs.

Sjögren E, Hedeland M, Bondesson U, Lennernäs H.

Eur J Pharm Sci. 2014 Jun 16;57:214-23. doi: 10.1016/j.ejps.2013.09.014. Epub 2013 Sep 27.

PMID:
24075962
47.

Synthesis, characterization, and detection of new oxandrolone metabolites as long-term markers in sports drug testing.

Guddat S, Fußhöller G, Beuck S, Thomas A, Geyer H, Rydevik A, Bondesson U, Hedeland M, Lagojda A, Schänzer W, Thevis M.

Anal Bioanal Chem. 2013 Oct;405(25):8285-94. doi: 10.1007/s00216-013-7218-1. Epub 2013 Jul 23.

PMID:
23877183
48.

Mass spectrometric characterization of glucuronides formed by a new concept, combining Cunninghamella elegans with TEMPO.

Rydevik A, Bondesson U, Thevis M, Hedeland M.

J Pharm Biomed Anal. 2013 Oct;84:278-84. doi: 10.1016/j.jpba.2013.06.012. Epub 2013 Jun 28.

PMID:
23867089
49.

The fungus Cunninghamella elegans can produce human and equine metabolites of selective androgen receptor modulators (SARMs).

Rydevik A, Thevis M, Krug O, Bondesson U, Hedeland M.

Xenobiotica. 2013 May;43(5):409-20. doi: 10.3109/00498254.2012.729102. Epub 2012 Nov 15.

PMID:
23153056
50.

High inter-individual variability of vardenafil pharmacokinetics in patients with pulmonary hypertension.

Sandqvist AM, Henrohn D, Schneede J, Hedeland M, Egeröd HC, Bondesson UG, Wikström BG.

Eur J Clin Pharmacol. 2013 Feb;69(2):197-207. doi: 10.1007/s00228-012-1323-5. Epub 2012 Jun 26.

PMID:
22732766

Supplemental Content

Loading ...
Support Center