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Items: 5

1.

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma.

Hector A, Montgomery EA, Karikari C, Canto M, Dunbar KB, Wang JS, Feldmann G, Hong SM, Haffner MC, Meeker AK, Holland SJ, Yu J, Heckrodt TJ, Zhang J, Ding P, Goff D, Singh R, Roa JC, Marimuthu A, Riggins GJ, Eshleman JR, Nelkin BD, Pandey A, Maitra A.

Cancer Biol Ther. 2010 Nov 15;10(10):1009-18. doi: 10.4161/cbt.10.10.13248. Epub 2010 Nov 15.

2.

R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.

Holland SJ, Pan A, Franci C, Hu Y, Chang B, Li W, Duan M, Torneros A, Yu J, Heckrodt TJ, Zhang J, Ding P, Apatira A, Chua J, Brandt R, Pine P, Goff D, Singh R, Payan DG, Hitoshi Y.

Cancer Res. 2010 Feb 15;70(4):1544-54. doi: 10.1158/0008-5472.CAN-09-2997. Epub 2010 Feb 9.

3.

Cobalt-mediated [2+2+2] cycloaddition versus C-H and N-H activation of pyridones and pyrazinones with alkynes: an experimental study.

Aubert C, Betschmann P, Eichberg MJ, Gandon V, Heckrodt TJ, Lehmann J, Malacria M, Masjost B, Paredes E, Vollhardt KP, Whitener GD.

Chemistry. 2007;13(26):7443-65.

PMID:
17579900
4.

Cobalt-mediated [2+2+2] cycloaddition versus C-H and N-H activation of 2-pyridones and pyrazinones with alkynes: a theoretical study.

Aubert C, Gandon V, Geny A, Heckrodt TJ, Malacria M, Paredes E, Vollhardt KP.

Chemistry. 2007;13(26):7466-78.

PMID:
17579899
5.

Total synthesis of Elisabethin A: intramolecular Diels-Alder reaction under biomimetic conditions.

Heckrodt TJ, Mulzer J.

J Am Chem Soc. 2003 Apr 23;125(16):4680-1. Erratum in: J Am Chem Soc. 2003 Aug 6;125(31):9538.

PMID:
12696865

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