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Items: 21


LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.

Heckmann BL, Teubner BJW, Tummers B, Boada-Romero E, Harris L, Yang M, Guy CS, Zakharenko SS, Green DR.

Cell. 2019 Jul 25;178(3):536-551.e14. doi: 10.1016/j.cell.2019.05.056. Epub 2019 Jun 27.


Correction: LC3-associated phagocytosis at a glance (doi:10.1242/jcs.222984).

Heckmann BL, Green DR.

J Cell Sci. 2019 Mar 7;132(5). pii: jcs231472. doi: 10.1242/jcs.231472. No abstract available.


Identification of an intrinsic lysophosphatidic acid acyltransferase activity in the lipolytic inhibitor G0/G1 switch gene 2 (G0S2).

Zhang X, Xie X, Heckmann BL, Saarinen AM, Gu H, Zechner R, Liu J.

FASEB J. 2019 May;33(5):6655-6666. doi: 10.1096/fj.201802502R. Epub 2019 Feb 25.


LC3-associated phagocytosis at a glance.

Heckmann BL, Green DR.

J Cell Sci. 2019 Feb 20;132(5). pii: jcs222984. doi: 10.1242/jcs.222984. Review. Erratum in: J Cell Sci. 2019 Mar 7;132(5):.


To the edge of cell death and back.

Gong YN, Crawford JC, Heckmann BL, Green DR.

FEBS J. 2019 Feb;286(3):430-440. doi: 10.1111/febs.14714. Epub 2018 Dec 19. Review.


Osteoblast autophagy in glucocorticoid-induced osteoporosis.

Wang L, Heckmann BL, Yang X, Long H.

J Cell Physiol. 2019 Apr;234(4):3207-3215. doi: 10.1002/jcp.27335. Epub 2018 Nov 11. Review.


Crashing the computer: apoptosis vs. necroptosis in neuroinflammation.

Heckmann BL, Tummers B, Green DR.

Cell Death Differ. 2019 Jan;26(1):41-52. doi: 10.1038/s41418-018-0195-3. Epub 2018 Oct 19.


LC3-Associated Phagocytosis and Inflammation.

Heckmann BL, Boada-Romero E, Cunha LD, Magne J, Green DR.

J Mol Biol. 2017 Nov 24;429(23):3561-3576. doi: 10.1016/j.jmb.2017.08.012. Epub 2017 Aug 25. Review.


G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux.

Zhang X, Heckmann BL, Campbell LE, Liu J.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt B):1146-1154. doi: 10.1016/j.bbalip.2017.06.007. Epub 2017 Jun 21. Review.


Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression.

Heckmann BL, Zhang X, Saarinen AM, Schoiswohl G, Kershaw EE, Zechner R, Liu J.

JCI Insight. 2017 Feb 23;2(4):e88735. doi: 10.1172/jci.insight.88735.


Regulation of G0/G1 Switch Gene 2 (G0S2) Protein Ubiquitination and Stability by Triglyceride Accumulation and ATGL Interaction.

Heckmann BL, Zhang X, Saarinen AM, Liu J.

PLoS One. 2016 Jun 1;11(6):e0156742. doi: 10.1371/journal.pone.0156742. eCollection 2016.


Regulation of FSP27 protein stability by AMPK and HSC70.

Zhang X, Heckmann BL, Xie X, Saarinen AM, Liu J.

Am J Physiol Endocrinol Metab. 2014 Dec 1;307(11):E1047-56. doi: 10.1152/ajpendo.00125.2014. Epub 2014 Oct 14.


Identification of a novel phosphorylation site in adipose triglyceride lipase as a regulator of lipid droplet localization.

Xie X, Langlais P, Zhang X, Heckmann BL, Saarinen AM, Mandarino LJ, Liu J.

Am J Physiol Endocrinol Metab. 2014 Jun 15;306(12):E1449-59. doi: 10.1152/ajpendo.00663.2013. Epub 2014 May 6.


Defective adipose lipolysis and altered global energy metabolism in mice with adipose overexpression of the lipolytic inhibitor G0/G1 switch gene 2 (G0S2).

Heckmann BL, Zhang X, Xie X, Saarinen A, Lu X, Yang X, Liu J.

J Biol Chem. 2014 Jan 24;289(4):1905-16. doi: 10.1074/jbc.M113.522011. Epub 2013 Dec 3.


Targeted disruption of G0/G1 switch gene 2 enhances adipose lipolysis, alters hepatic energy balance, and alleviates high-fat diet-induced liver steatosis.

Zhang X, Xie X, Heckmann BL, Saarinen AM, Czyzyk TA, Liu J.

Diabetes. 2014 Mar;63(3):934-46. doi: 10.2337/db13-1422. Epub 2013 Nov 5.


Studying lipolysis in adipocytes by combining siRNA knockdown and adenovirus-mediated overexpression approaches.

Zhang X, Heckmann BL, Liu J.

Methods Cell Biol. 2013;116:83-105. doi: 10.1016/B978-0-12-408051-5.00006-1.


Distinct mechanisms regulate ATGL-mediated adipocyte lipolysis by lipid droplet coat proteins.

Yang X, Heckmann BL, Zhang X, Smas CM, Liu J.

Mol Endocrinol. 2013 Jan;27(1):116-26. doi: 10.1210/me.2012-1178. Epub 2012 Nov 30.


The G0/G1 switch gene 2 (G0S2): regulating metabolism and beyond.

Heckmann BL, Zhang X, Xie X, Liu J.

Biochim Biophys Acta. 2013 Feb;1831(2):276-81. doi: 10.1016/j.bbalip.2012.09.016. Epub 2012 Sep 29. Review.


Identification of a role for CLASP2 in insulin action.

Langlais P, Dillon JL, Mengos A, Baluch DP, Ardebili R, Miranda DN, Xie X, Heckmann BL, Liu J, Mandarino LJ.

J Biol Chem. 2012 Nov 9;287(46):39245-53. doi: 10.1074/jbc.M112.394148. Epub 2012 Sep 19.


The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes.

Heckmann BL, Yang X, Zhang X, Liu J.

Br J Pharmacol. 2013 Jan;168(1):163-71. doi: 10.1111/j.1476-5381.2012.02110.x.


Relative contribution of adipose triglyceride lipase and hormone-sensitive lipase to tumor necrosis factor-α (TNF-α)-induced lipolysis in adipocytes.

Yang X, Zhang X, Heckmann BL, Lu X, Liu J.

J Biol Chem. 2011 Nov 25;286(47):40477-85. doi: 10.1074/jbc.M111.257923. Epub 2011 Oct 3.

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