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Items: 23


MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload.

Ribeiro Junior RF, Dabkowski ER, Shekar KC, O Connell KA, Hecker PA, Murphy MP.

Free Radic Biol Med. 2018 Mar;117:18-29. doi: 10.1016/j.freeradbiomed.2018.01.012. Epub 2018 Feb 2.


Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

Ackermann MA, King B, Lieberman NAP, Bobbili PJ, Rudloff M, Berndsen CE, Wright NT, Hecker PA, Kontrogianni-Konstantopoulos A.

J Mol Cell Cardiol. 2017 Oct;111:27-39. doi: 10.1016/j.yjmcc.2017.08.004. Epub 2017 Aug 4.


Deregulated Ca2+ cycling underlies the development of arrhythmia and heart disease due to mutant obscurin.

Hu LR, Ackermann MA, Hecker PA, Prosser BL, King B, O'Connell KA, Grogan A, Meyer LC, Berndsen CE, Wright NT, Jonathan Lederer W, Kontrogianni-Konstantopoulos A.

Sci Adv. 2017 Jun 7;3(6):e1603081. doi: 10.1126/sciadv.1603081. eCollection 2017 Jun.


Cardiac Disease Status Dictates Functional mRNA Targeting Profiles of Individual MicroRNAs.

Matkovich SJ, Dorn GW 2nd, Grossenheider TC, Hecker PA.

Circ Cardiovasc Genet. 2015 Dec;8(6):774-84. doi: 10.1161/CIRCGENETICS.115.001237. Epub 2015 Nov 9.


Cardiac mitochondrial proteome dynamics with heavy water reveals stable rate of mitochondrial protein synthesis in heart failure despite decline in mitochondrial oxidative capacity.

Shekar KC, Li L, Dabkowski ER, Xu W, Ribeiro RF Jr, Hecker PA, Recchia FA, Sadygov RG, Willard B, Kasumov T, Stanley WC.

J Mol Cell Cardiol. 2014 Oct;75:88-97. doi: 10.1016/j.yjmcc.2014.06.014. Epub 2014 Jul 1.


Effect of a high-protein diet on development of heart failure in response to pressure overload.

Ribeiro RF Jr, Dabkowski ER, O'Connell KA, Xu W, Galvao Tde F, Hecker PA, Shekar KC, Stefanon I, Stanley WC.

Appl Physiol Nutr Metab. 2014 Feb;39(2):238-47. doi: 10.1139/apnm-2013-0274. Epub 2013 Sep 11.


Docosahexaenoic acid supplementation alters key properties of cardiac mitochondria and modestly attenuates development of left ventricular dysfunction in pressure overload-induced heart failure.

Dabkowski ER, O'Connell KA, Xu W, Ribeiro RF Jr, Hecker PA, Shekar KC, Daneault C, Des Rosiers C, Stanley WC.

Cardiovasc Drugs Ther. 2013 Dec;27(6):499-510. doi: 10.1007/s10557-013-6487-4.


Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction.

Wang H, Sreenivasan U, Gong DW, O'Connell KA, Dabkowski ER, Hecker PA, Ionica N, Konig M, Mahurkar A, Sun Y, Stanley WC, Sztalryd C.

J Lipid Res. 2013 Apr;54(4):953-65. doi: 10.1194/jlr.M032466. Epub 2013 Jan 23.


Impact of glucose-6-phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease.

Hecker PA, Leopold JA, Gupte SA, Recchia FA, Stanley WC.

Am J Physiol Heart Circ Physiol. 2013 Feb 15;304(4):H491-500. doi: 10.1152/ajpheart.00721.2012. Epub 2012 Dec 15. Review.


Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs: effects of aging and long-term aldosterone infusion.

Asemu G, O'Connell KA, Cox JW, Dabkowski ER, Xu W, Ribeiro RF Jr, Shekar KC, Hecker PA, Rastogi S, Sabbah HN, Hoppel CL, Stanley WC.

Am J Physiol Heart Circ Physiol. 2013 Feb 15;304(4):H514-28. doi: 10.1152/ajpheart.00674.2012. Epub 2012 Dec 15.


Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure.

Hecker PA, Lionetti V, Ribeiro RF Jr, Rastogi S, Brown BH, O'Connell KA, Cox JW, Shekar KC, Gamble DM, Sabbah HN, Leopold JA, Gupte SA, Recchia FA, Stanley WC.

Circ Heart Fail. 2013 Jan;6(1):118-26. doi: 10.1161/CIRCHEARTFAILURE.112.969576. Epub 2012 Nov 20.


Epitranscriptional orchestration of genetic reprogramming is an emergent property of stress-regulated cardiac microRNAs.

Hu Y, Matkovich SJ, Hecker PA, Zhang Y, Edwards JR, Dorn GW 2nd.

Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19864-9. doi: 10.1073/pnas.1214996109. Epub 2012 Nov 12.


Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival.

Galvao TF, Khairallah RJ, Dabkowski ER, Brown BH, Hecker PA, O'Connell KA, O'Shea KM, Sabbah HN, Rastogi S, Daneault C, Des Rosiers C, Stanley WC.

Am J Physiol Heart Circ Physiol. 2013 Jan 1;304(1):H12-21. doi: 10.1152/ajpheart.00657.2012. Epub 2012 Oct 26.


Effects of glucose-6-phosphate dehydrogenase deficiency on the metabolic and cardiac responses to obesogenic or high-fructose diets.

Hecker PA, Mapanga RF, Kimar CP, Ribeiro RF Jr, Brown BH, O'Connell KA, Cox JW, Shekar KC, Asemu G, Essop MF, Stanley WC.

Am J Physiol Endocrinol Metab. 2012 Oct 15;303(8):E959-72. doi: 10.1152/ajpendo.00202.2012. Epub 2012 Jul 24.


High-sugar intake does not exacerbate metabolic abnormalities or cardiac dysfunction in genetic cardiomyopathy.

Hecker PA, Galvao TF, O'Shea KM, Brown BH, Henderson R Jr, Riggle H, Gupte SA, Stanley WC.

Nutrition. 2012 May;28(5):520-6. doi: 10.1016/j.nut.2011.09.017. Epub 2012 Feb 2.


High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects.

Galvao TF, Brown BH, Hecker PA, O'Connell KA, O'Shea KM, Sabbah HN, Rastogi S, Daneault C, Des Rosiers C, Stanley WC.

Cardiovasc Res. 2012 Jan 1;93(1):24-32. doi: 10.1093/cvr/cvr258. Epub 2011 Sep 29.


Role of adiponectin in the development of high fat diet-induced metabolic abnormalities in mice.

Hecker PA, O'Shea KM, Galvao TF, Brown BH, Stanley WC.

Horm Metab Res. 2011 Feb;43(2):100-5. doi: 10.1055/s-0030-1269898. Epub 2010 Dec 16.


ω-3 Polyunsaturated fatty acids prevent pressure overload-induced ventricular dilation and decrease in mitochondrial enzymes despite no change in adiponectin.

O'Shea KM, Chess DJ, Khairallah RJ, Hecker PA, Lei B, Walsh K, Des Rosiers C, Stanley WC.

Lipids Health Dis. 2010 Sep 6;9:95. doi: 10.1186/1476-511X-9-95.


Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.

Khairallah RJ, Sparagna GC, Khanna N, O'Shea KM, Hecker PA, Kristian T, Fiskum G, Des Rosiers C, Polster BM, Stanley WC.

Biochim Biophys Acta. 2010 Aug;1797(8):1555-62. doi: 10.1016/j.bbabio.2010.05.007. Epub 2010 May 21.


Effects of adiponectin deficiency on structural and metabolic remodeling in mice subjected to pressure overload.

O'Shea KM, Chess DJ, Khairallah RJ, Rastogi S, Hecker PA, Sabbah HN, Walsh K, Stanley WC.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1639-45. doi: 10.1152/ajpheart.00957.2009. Epub 2010 Mar 26.


Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.

O'Shea KM, Khairallah RJ, Sparagna GC, Xu W, Hecker PA, Robillard-Frayne I, Des Rosiers C, Kristian T, Murphy RC, Fiskum G, Stanley WC.

J Mol Cell Cardiol. 2009 Dec;47(6):819-27. doi: 10.1016/j.yjmcc.2009.08.014. Epub 2009 Aug 22.


Effect of tsetse control on trypanosome prevalence in livestock: problems of experimental design and statistical interpretation--a case study in northern Côte d'Ivoire.

Rowlands GJ, Coulibaly L, Hecker PA, d'Ieteren GD, Leak SG, Authié E.

Vet Parasitol. 1996 Jun;63(3-4):199-214.


[Effect of sound on milk production in cows].

Sambraus HH, Hecker PA.

Berl Munch Tierarztl Wochenschr. 1985 Sep 1;98(9):298-302. German. No abstract available.


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