Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 586


Histone interaction landscapes visualized by crosslinking mass spectrometry in intact cell nuclei.

Fasci D, van Ingen H, Scheltema RA, Heck AJR.

Mol Cell Proteomics. 2018 Jul 18. pii: mcp.RA118.000924. doi: 10.1074/mcp.RA118.000924. [Epub ahead of print]


A Protein-Based Encapsulation System with Calcium-Controlled Cargo Loading and Detachment.

Lizatović R, Assent M, Barendregt A, Dahlin J, Bille A, Satzinger K, Tupina D, Heck AJR, Wennmalm S, André I.

Angew Chem Int Ed Engl. 2018 Jul 5. doi: 10.1002/anie.201806466. [Epub ahead of print]


A system-wide approach to monitor responses to synergistic BRAF and EGFR inhibition in colorectal cancer cells.

Ressa A, Bosdriesz E, de Ligt J, Mainardi S, Maddalo G, Prahallad A, Jager M, de la Fonteijne L, Fitzpatrick M, Groten S, Altelaar AFM, Bernards R, Cuppen E, Wessels L, Heck AJR.

Mol Cell Proteomics. 2018 Jul 3. pii: mcp.RA117.000486. doi: 10.1074/mcp.RA117.000486. [Epub ahead of print]


Similar Albeit Not the Same: In-Depth Analysis of Proteoforms of Human Serum, Bovine Serum, and Recombinant Human Fetuin.

Lin YH, Franc V, Heck AJR.

J Proteome Res. 2018 Aug 3;17(8):2861-2869. doi: 10.1021/acs.jproteome.8b00318. Epub 2018 Jul 13.


Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods.

van de Waterbeemd M, Tamara S, Fort KL, Damoc E, Franc V, Bieri P, Itten M, Makarov A, Ban N, Heck AJR.

Nat Commun. 2018 Jun 27;9(1):2493. doi: 10.1038/s41467-018-04853-x.


Inheritance of the Golgi Apparatus and Cytokinesis Are Controlled by Degradation of GBF1.

Magliozzi R, Carrero ZI, Low TY, Yuniati L, Valdes-Quezada C, Kruiswijk F, van Wijk K, Heck AJR, Jackson CL, Guardavaccaro D.

Cell Rep. 2018 Jun 12;23(11):3381-3391.e4. doi: 10.1016/j.celrep.2018.05.031.


Actin from the apicomplexan Neospora caninum (NcACT) has different isoforms in 2D electrophoresis.

Baroni L, Pollo-Oliveira L, Heck AJ, Altelaar AM, Yatsuda AP.

Parasitology. 2018 Jun 6:1-9. doi: 10.1017/S0031182018000872. [Epub ahead of print]


Mix and match of the tumor metastasis suppressor Nm23 protein isoforms in vitro and in vivo.

Potel CM, Fasci D, Heck AJR.

FEBS J. 2018 Jun 4. doi: 10.1111/febs.14525. [Epub ahead of print]


Vaccine antigens modulate the innate response of monocytes to Al(OH)3.

Kooijman S, Brummelman J, van Els CACM, Marino F, Heck AJR, van Riet E, Metz B, Kersten GFA, Pennings JLA, Meiring HD.

PLoS One. 2018 May 29;13(5):e0197885. doi: 10.1371/journal.pone.0197885. eCollection 2018.


Minimal Information About an Immuno-Peptidomics Experiment (MIAIPE).

Lill JR, van Veelen PA, Tenzer S, Admon A, Caron E, Elias JE, Heck AJR, Marcilla M, Marino F, Müller M, Peters B, Purcell A, Sette A, Sturm T, Ternette N, Vizcaíno JA, Bassani-Sternberg M.

Proteomics. 2018 Jun;18(12):e1800110. doi: 10.1002/pmic.201800110.


Bacterial encapsulins as orthogonal compartments for mammalian cell engineering.

Sigmund F, Massner C, Erdmann P, Stelzl A, Rolbieski H, Desai M, Bricault S, Wörner TP, Snijder J, Geerlof A, Fuchs H, Hrabĕ de Angelis M, Heck AJR, Jasanoff A, Ntziachristos V, Plitzko J, Westmeyer GG.

Nat Commun. 2018 May 18;9(1):1990. doi: 10.1038/s41467-018-04227-3.


Distinct Stabilities of the Structurally Homologous Heptameric Co-Chaperonins GroES and gp31.

Dyachenko A, Tamara S, Heck AJR.

J Am Soc Mass Spectrom. 2018 May 7. doi: 10.1007/s13361-018-1910-5. [Epub ahead of print]


Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe.

van der Laarse SAM, Leney AC, Heck AJR.

FEBS J. 2018 May 2. doi: 10.1111/febs.14491. [Epub ahead of print] Review.


Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.

Chiang DY, Alsina KM, Corradini E, Fitzpatrick M, Ni L, Lahiri SK, Reynolds J, Pan X, Scott L Jr, Heck AJR, Wehrens XH.

Circulation. 2018 Apr 18. pii: CIRCULATIONAHA.118.034361. doi: 10.1161/CIRCULATIONAHA.118.034361. [Epub ahead of print]


CTGF/VEGFA-activated Fibroblasts Promote Tumor Migration Through Micro-environmental Modulation.

Wu W, Zaal EA, Berkers CR, Lemeer S, Heck AJR.

Mol Cell Proteomics. 2018 Aug;17(8):1502-1514. doi: 10.1074/mcp.RA118.000708. Epub 2018 Apr 18.


TMEM59 potentiates Wnt signaling by promoting signalosome formation.

Gerlach JP, Jordens I, Tauriello DVF, van 't Land-Kuper I, Bugter JM, Noordstra I, van der Kooij J, Low TY, Pimentel-Muiños FX, Xanthakis D, Fenderico N, Rabouille C, Heck AJR, Egan DA, Maurice MM.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3996-E4005. doi: 10.1073/pnas.1721321115. Epub 2018 Apr 9.


TREM-1 multimerization is essential for its activation on monocytes and neutrophils.

Carrasco K, Boufenzer A, Jolly L, Le Cordier H, Wang G, Heck AJ, Cerwenka A, Vinolo E, Nazabal A, Kriznik A, Launay P, Gibot S, Derive M.

Cell Mol Immunol. 2018 Mar 22. doi: 10.1038/s41423-018-0003-5. [Epub ahead of print]


Comprehensive Proteoform Characterization of Plasma Complement Component C8αβγ by Hybrid Mass Spectrometry Approaches.

Franc V, Zhu J, Heck AJR.

J Am Soc Mass Spectrom. 2018 Jun;29(6):1099-1110. doi: 10.1007/s13361-018-1901-6. Epub 2018 Mar 12.


Defeating Major Contaminants in Fe3+- Immobilized Metal Ion Affinity Chromatography (IMAC) Phosphopeptide Enrichment.

Potel CM, Lin MH, Heck AJR, Lemeer S.

Mol Cell Proteomics. 2018 May;17(5):1028-1034. doi: 10.1074/mcp.TIR117.000518. Epub 2018 Feb 15.


Doxorubicin-induced DNA damage causes extensive ubiquitination of ribosomal proteins associated with a decrease in protein translation.

Halim VA, García-Santisteban I, Warmerdam DO, van den Broek B, Heck AJR, Mohammed S, Medema RH.

Mol Cell Proteomics. 2018 Feb 8. pii: mcp.RA118.000652. doi: 10.1074/mcp.RA118.000652. [Epub ahead of print]


Widespread bacterial protein histidine phosphorylation revealed by mass spectrometry-based proteomics.

Potel CM, Lin MH, Heck AJR, Lemeer S.

Nat Methods. 2018 Mar;15(3):187-190. doi: 10.1038/nmeth.4580. Epub 2018 Jan 29.


Parsimonious Charge Deconvolution for Native Mass Spectrometry.

Bern M, Caval T, Kil YJ, Tang W, Becker C, Carlson E, Kletter D, Sen KI, Galy N, Hagemans D, Franc V, Heck AJR.

J Proteome Res. 2018 Mar 2;17(3):1216-1226. doi: 10.1021/acs.jproteome.7b00839. Epub 2018 Feb 8.


A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7.

Bockelmann S, Mina JGM, Korneev S, Hassan DG, Müller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, Holthuis JCM.

J Lipid Res. 2018 Mar;59(3):515-530. doi: 10.1194/jlr.M082354. Epub 2018 Jan 17.


Functional Impact of the N-terminal Arm of Proline Dehydrogenase from Thermus thermophilus.

Huijbers MME, van Alen I, Wu JW, Barendregt A, Heck AJR, van Berkel WJH.

Molecules. 2018 Jan 16;23(1). pii: E184. doi: 10.3390/molecules23010184.


Novel identified aluminum hydroxide-induced pathways prove monocyte activation and pro-inflammatory preparedness.

Kooijman S, Brummelman J, van Els CACM, Marino F, Heck AJR, Mommen GPM, Metz B, Kersten GFA, Pennings JLA, Meiring HD.

J Proteomics. 2018 Mar 20;175:144-155. doi: 10.1016/j.jprot.2017.12.021. Epub 2018 Jan 6.


Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer.

Fort KL, Cramer CN, Voinov VG, Vasil'ev YV, Lopez NI, Beckman JS, Heck AJR.

J Proteome Res. 2018 Feb 2;17(2):926-933. doi: 10.1021/acs.jproteome.7b00622. Epub 2017 Dec 28.


The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

Liu F, Lössl P, Rabbitts BM, Balaban RS, Heck AJR.

Mol Cell Proteomics. 2018 Feb;17(2):216-232. doi: 10.1074/mcp.RA117.000470. Epub 2017 Dec 8.


Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.

Leloup N, Lössl P, Meijer DH, Brennich M, Heck AJR, Thies-Weesie DME, Janssen BJC.

Nat Commun. 2017 Nov 22;8(1):1708. doi: 10.1038/s41467-017-01485-5.


Connecting color with assembly in the fluorescent B-phycoerythrin protein complex.

Leney AC, Tschanz A, Heck AJR.

FEBS J. 2018 Jan;285(1):178-187. doi: 10.1111/febs.14331. Epub 2017 Nov 28.


Expanding the structural analysis capabilities on an Orbitrap-based mass spectrometer for large macromolecular complexes.

Fort KL, van de Waterbeemd M, Boll D, Reinhardt-Szyba M, Belov ME, Sasaki E, Zschoche R, Hilvert D, Makarov AA, Heck AJR.

Analyst. 2017 Dec 18;143(1):100-105. doi: 10.1039/c7an01629h.


Stochastic palmitoylation of accessible cysteines in membrane proteins revealed by native mass spectrometry.

Rodenburg RNP, Snijder J, van de Waterbeemd M, Schouten A, Granneman J, Heck AJR, Gros P.

Nat Commun. 2017 Nov 3;8(1):1280. doi: 10.1038/s41467-017-01461-z.


Facilitating identification of minimal protein binding domains by cross-linking mass spectrometry.

Liu Q, Remmelzwaal S, Heck AJR, Akhmanova A, Liu F.

Sci Rep. 2017 Oct 18;7(1):13453. doi: 10.1038/s41598-017-13663-y.


Phosphoproteomics Reveals Regulatory T Cell-Mediated DEF6 Dephosphorylation That Affects Cytokine Expression in Human Conventional T Cells.

Joshi RN, Binai NA, Marabita F, Sui Z, Altman A, Heck AJR, Tegnér J, Schmidt A.

Front Immunol. 2017 Sep 25;8:1163. doi: 10.3389/fimmu.2017.01163. eCollection 2017.


The SysteMHC Atlas project.

Shao W, Pedrioli PGA, Wolski W, Scurtescu C, Schmid E, Vizcaíno JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL, Zubarev RA, Ytterberg AJ, Purcell AW, Marcilla M, Paradela A, Wang Q, Costello CE, Ternette N, van Veelen PA, van Els CACM, Heck AJR, de Souza GA, Sollid LM, Admon A, Stevanovic S, Rammensee HG, Thibault P, Perreault C, Bassani-Sternberg M, Aebersold R, Caron E.

Nucleic Acids Res. 2018 Jan 4;46(D1):D1237-D1247. doi: 10.1093/nar/gkx664.


Phosphate Transfer in Activated Protein Complexes Reveals Interaction Sites.

Tamara S, Scheltema RA, Heck AJR, Leney AC.

Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13641-13644. doi: 10.1002/anie.201706749. Epub 2017 Sep 27.


Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.

Mezzadra R, Sun C, Jae LT, Gomez-Eerland R, de Vries E, Wu W, Logtenberg MEW, Slagter M, Rozeman EA, Hofland I, Broeks A, Horlings HM, Wessels LFA, Blank CU, Xiao Y, Heck AJR, Borst J, Brummelkamp TR, Schumacher TNM.

Nature. 2017 Sep 7;549(7670):106-110. doi: 10.1038/nature23669. Epub 2017 Aug 16.


Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation.

Leney AC, El Atmioui D, Wu W, Ovaa H, Heck AJR.

Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7255-E7261. doi: 10.1073/pnas.1620529114. Epub 2017 Aug 14.


A community proposal to integrate proteomics activities in ELIXIR.

Vizcaíno JA, Walzer M, Jiménez RC, Bittremieux W, Bouyssié D, Carapito C, Corrales F, Ferro M, Heck AJR, Horvatovich P, Hubalek M, Lane L, Laukens K, Levander F, Lisacek F, Novak P, Palmblad M, Piovesan D, Pühler A, Schwämmle V, Valkenborg D, van Rijswijk M, Vondrasek J, Eisenacher M, Martens L, Kohlbacher O.

F1000Res. 2017 Jun 13;6. pii: ELIXIR-875. doi: 10.12688/f1000research.11751.1. eCollection 2017.


3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.

Montersino S, Te Poele E, Orru R, Westphal AH, Barendregt A, Heck AJR, van der Geize R, Dijkhuizen L, Mattevi A, van Berkel WJH.

Front Microbiol. 2017 Jun 16;8:1110. doi: 10.3389/fmicb.2017.01110. eCollection 2017.


Erratum: Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.

Jiang K, Rezabkova L, Hua S, Liu Q, Capitani G, Altelaar AFM, Heck AJR, Kammerer RA, Steinmetz MO, Akhmanova A.

Nat Cell Biol. 2017 Jun 29;19(7):873. doi: 10.1038/ncb3557.


Aspergillus niger Prolyl Endoprotease for Hydrogen-Deuterium Exchange Mass Spectrometry and Protein Structural Studies.

Tsiatsiani L, Akeroyd M, Olsthoorn M, Heck AJR.

Anal Chem. 2017 Aug 1;89(15):7966-7973. doi: 10.1021/acs.analchem.7b01161. Epub 2017 Jul 12.


Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.

Fagerlund RD, Wilkinson ME, Klykov O, Barendregt A, Pearce FG, Kieper SN, Maxwell HWR, Capolupo A, Heck AJR, Krause KL, Bostina M, Scheltema RA, Staals RHJ, Fineran PC.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5122-E5128. doi: 10.1073/pnas.1618421114. Epub 2017 Jun 13.


Direct Monitoring of Protein O-GlcNAcylation by High-Resolution Native Mass Spectrometry.

Leney AC, Rafie K, van Aalten DMF, Heck AJR.

ACS Chem Biol. 2017 Aug 18;12(8):2078-2084. doi: 10.1021/acschembio.7b00371. Epub 2017 Jun 28.


Proteasome Activation by Small Molecules.

Leestemaker Y, de Jong A, Witting KF, Penning R, Schuurman K, Rodenko B, Zaal EA, van de Kooij B, Laufer S, Heck AJR, Borst J, Scheper W, Berkers CR, Ovaa H.

Cell Chem Biol. 2017 Jun 22;24(6):725-736.e7. doi: 10.1016/j.chembiol.2017.05.010. Epub 2017 May 25.


Glycoproteomics: A Balance between High-Throughput and In-Depth Analysis.

Yang Y, Franc V, Heck AJR.

Trends Biotechnol. 2017 Jul;35(7):598-609. doi: 10.1016/j.tibtech.2017.04.010. Epub 2017 May 17. Review.


Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

Liu F, Lössl P, Scheltema R, Viner R, Heck AJR.

Nat Commun. 2017 May 19;8:15473. doi: 10.1038/ncomms15473.


Human CD62Ldim neutrophils identified as a separate subset by proteome profiling and in vivo pulse-chase labeling.

Tak T, Wijten P, Heeres M, Pickkers P, Scholten A, Heck AJR, Vrisekoop N, Leenen LP, Borghans JAM, Tesselaar K, Koenderman L.

Blood. 2017 Jun 29;129(26):3476-3485. doi: 10.1182/blood-2016-07-727669. Epub 2017 May 17.


Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.

Jiang K, Rezabkova L, Hua S, Liu Q, Capitani G, Altelaar AFM, Heck AJR, Kammerer RA, Steinmetz MO, Akhmanova A.

Nat Cell Biol. 2017 May;19(5):480-492. doi: 10.1038/ncb3511. Epub 2017 Apr 24. Erratum in: Nat Cell Biol. 2017 Jun 29;19(7):873.


Enhancing Accuracy in Molecular Weight Determination of Highly Heterogeneously Glycosylated Proteins by Native Tandem Mass Spectrometry.

Wang G, de Jong RN, van den Bremer ETJ, Parren PWHI, Heck AJR.

Anal Chem. 2017 May 2;89(9):4793-4797. doi: 10.1021/acs.analchem.6b05129. Epub 2017 Apr 13.


Vertex-Specific Proteins pUL17 and pUL25 Mechanically Reinforce Herpes Simplex Virus Capsids.

Snijder J, Radtke K, Anderson F, Scholtes L, Corradini E, Baines J, Heck AJR, Wuite GJL, Sodeik B, Roos WH.

J Virol. 2017 May 26;91(12). pii: e00123-17. doi: 10.1128/JVI.00123-17. Print 2017 Jun 15.

Supplemental Content

Support Center