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Items: 1 to 50 of 702

1.

Opportunities for evaluating chemical exposures and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) Program.

Buckley JP, Barrett ES, Beamer PI, Bennett DH, Bloom MS, Fennell TR, Fry RC, Funk WE, Hamra GB, Hecht SS, Kannan K, Iyer R, Karagas MR, Lyall K, Parsons PJ, Pellizzari ED, Signes-Pastor AJ, Starling AP, Wang A, Watkins DJ, Zhang M, Woodruff TJ; program collaborators for ECHO.

J Expo Sci Environ Epidemiol. 2020 Feb 17. doi: 10.1038/s41370-020-0211-9. [Epub ahead of print] Review.

PMID:
32066883
2.

Applying tobacco, environmental and dietary-related biomarkers to understand cancer etiology and evaluate prevention strategies.

Peterson LA, Balbo S, Fujioka N, Hatsukami DK, Hecht SS, Murphy SE, Stepanov I, Tretyakova N, Turesky RJ, Villalta PW.

Cancer Epidemiol Biomarkers Prev. 2020 Feb 12. pii: cebp.1356.2019. doi: 10.1158/1055-9965.EPI-19-1356. [Epub ahead of print]

PMID:
32051197
3.

Biomarkers of Exposure among Adult Smokeless Tobacco Users in the Population Assessment of Tobacco and Health Study (Wave 1, 2013-2014).

Cheng YC, Reyes-Guzman CM, Christensen CH, Rostron BL, Edwards KC, Wang L, Feng J, Jarrett JM, Ward CD, Xia B, Kimmel HL, Conway K, Leggett C, Taylor K, Lawrence C, Niaura R, Travers MJ, Hyland A, Hecht SS, Hatsukami DK, Goniewicz ML, Borek N, Blount BC, van Bemmel DM.

Cancer Epidemiol Biomarkers Prev. 2020 Jan 27. doi: 10.1158/1055-9965.EPI-19-0766. [Epub ahead of print]

PMID:
31988072
4.

Resolution and Quantitation of Mercapturic Acids Derived from Crotonaldehyde, Methacrolein, and Methyl Vinyl Ketone in the Urine of Smokers and Nonsmokers.

Chen M, Carmella SG, Li Y, Zhao Y, Hecht SS.

Chem Res Toxicol. 2020 Feb 17;33(2):669-677. doi: 10.1021/acs.chemrestox.9b00491. Epub 2020 Jan 30.

PMID:
31957442
5.

Effects of 6-Week Use of Very Low Nicotine Content Cigarettes in Smokers With Serious Mental Illness.

Tidey JW, Colby SM, Denlinger-Apte RL, Goodwin C, Cioe PA, Cassidy RN, Swift RM, Lindgren BR, Rubin N, Murphy SE, Hecht SS, Hatsukami DK, Donny EC.

Nicotine Tob Res. 2019 Dec 23;21(Suppl 1):S38-S45. doi: 10.1093/ntr/ntz133.

6.

A Randomized Clinical Trial Examining the Effects of Instructions for Electronic Cigarette Use on Smoking-Related Behaviors, and Biomarkers of Exposure.

Hatsukami D, Meier E, Lindgren BR, Anderson A, Reisinger S, Norton K, Strayer L, Jensen J, Dick L, Murphy S, Carmella S, Tang MK, Chen M, Hecht SS, O'Connor RJ, Shields PG.

Nicotine Tob Res. 2019 Dec 12. pii: ntz233. doi: 10.1093/ntr/ntz233. [Epub ahead of print]

PMID:
31828315
7.

Effects of 2-Phenethyl Isothiocyanate on Metabolism of 1,3-Butadiene in Smokers.

Boldry EJ, Yuan JM, Carmella SG, Wang R, Tessier K, Hatsukami DK, Hecht SS, Tretyakova NY.

Cancer Prev Res (Phila). 2020 Jan;13(1):91-100. doi: 10.1158/1940-6207.CAPR-19-0296. Epub 2019 Nov 26.

PMID:
31771940
8.

FEMA GRAS assessment of natural flavor complexes: Cinnamomum and Myroxylon-derived flavoring ingredients.

Rietjens IMCM, Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rosol TJ, Davidsen JM, Harman CL, Murray IJ, Taylor SV.

Food Chem Toxicol. 2020 Jan;135:110949. doi: 10.1016/j.fct.2019.110949. Epub 2019 Nov 18.

9.

Cigarette Smokers vs. Co-users of Cannabis and Cigarettes: Exposure to Toxicants.

Meier E, Vandrey R, Rubin N, Pacek LR, Jensen JA, Donny EC, Hecht SS, Carmella SG, Murphy SE, Luo X, Stepanov I, Ikuemonisan J, Severson H, al'Absi M, Hatsukami DK.

Nicotine Tob Res. 2019 Oct 16. pii: ntz199. doi: 10.1093/ntr/ntz199. [Epub ahead of print]

PMID:
31616939
10.

FEMA GRAS assessment of natural flavor complexes: Mint, buchu, dill and caraway derived flavoring ingredients.

Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Bastaki M, Davidsen JM, Harman CL, McGowen MM, Taylor SV.

Food Chem Toxicol. 2020 Jan;135:110870. doi: 10.1016/j.fct.2019.110870. Epub 2019 Oct 8.

11.

Biochemical Verification of Tobacco Use and Abstinence: 2019 Update.

Benowitz NL, Bernert JT, Foulds J, Hecht SS, Jacob P, Jarvis MJ, Joseph A, Oncken C, Piper ME.

Nicotine Tob Res. 2019 Oct 1. pii: ntz132. doi: 10.1093/ntr/ntz132. [Epub ahead of print]

PMID:
31570931
12.

Oral Health Effects of Combusted and Smokeless Tobacco Products.

Tomar SL, Hecht SS, Jaspers I, Gregory RL, Stepanov I.

Adv Dent Res. 2019 Oct;30(1):4-10. doi: 10.1177/0022034519872480. Review.

PMID:
31538806
13.

Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers.

St Helen G, Benowitz NL, Ko J, Jacob P, Gregorich SE, Pérez-Stable EJ, Murphy SE, Hecht SS, Hatsukami DK, Donny EC.

J Expo Sci Environ Epidemiol. 2019 Aug 12. doi: 10.1038/s41370-019-0159-9. [Epub ahead of print]

PMID:
31406274
14.

A Randomized Clinical Trial of Snus Examining the Effect of Complete Versus Partial Cigarette Substitution on Smoking-Related Behaviors, and Biomarkers of Exposure.

Meier E, Lindgren BR, Anderson A, Reisinger SA, Norton KJ, Jensen J, Strayer L, Dick L, Tang MK, Chen M, Carmella SG, Hecht SS, Murphy SE, Yang J, Stepanov I, O'Connor RJ, Shields PG, Hatsukami DK.

Nicotine Tob Res. 2019 Apr 11. pii: ntz055. doi: 10.1093/ntr/ntz055. [Epub ahead of print]

PMID:
31321423
15.

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage.

McElroy JP, Carmella SG, Heskin AK, Tang MK, Murphy SE, Reisinger SA, Jensen JA, Hatsukami DK, Hecht SS, Shields PG.

PLoS One. 2019 Jun 28;14(6):e0218386. doi: 10.1371/journal.pone.0218386. eCollection 2019.

16.

Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects.

Hatsukami DK, Luo X, Heskin AK, Tang MK, Carmella SG, Jensen J, Robinson JD, Vandrey R, Drobes DJ, Strasser AA, al'Absi M, Leischow S, Cinciripini PM, Koopmeiners J, Ikuemonisan J, Benowitz NL, Donny EC, Hecht SS.

Addiction. 2019 Oct;114(10):1824-1833. doi: 10.1111/add.14695. Epub 2019 Jul 8.

PMID:
31140663
17.

Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation.

Carmella SG, Heskin AK, Tang MK, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami DK, Hecht SS.

PLoS One. 2019 Apr 25;14(4):e0215853. doi: 10.1371/journal.pone.0215853. eCollection 2019.

18.

Recent Studies on DNA Adducts Resulting from Human Exposure to Tobacco Smoke.

Ma B, Stepanov I, Hecht SS.

Toxics. 2019 Mar 19;7(1). pii: E16. doi: 10.3390/toxics7010016. Review.

19.

Methyl DNA phosphate adduct formation in lung tumor tissue and adjacent normal tissue of lung cancer patients.

Ma B, Villalta PW, Hochalter JB, Stepanov I, Hecht SS.

Carcinogenesis. 2019 Nov 25;40(11):1387-1394. doi: 10.1093/carcin/bgz053.

PMID:
30873516
20.

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.

Li Y, Ma B, Cao Q, Balbo S, Zhao L, Upadhyaya P, Hecht SS.

Chem Res Toxicol. 2019 Apr 15;32(4):773-783. doi: 10.1021/acs.chemrestox.9b00007. Epub 2019 Feb 26.

21.

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update.

Stram DO, Park SL, Haiman CA, Murphy SE, Patel Y, Hecht SS, Le Marchand L.

J Natl Cancer Inst. 2019 Aug 1;111(8):811-819. doi: 10.1093/jnci/djy206.

22.

Comparison of Nicotine and Toxicant Exposure in Users of Electronic Cigarettes and Combustible Cigarettes.

Goniewicz ML, Smith DM, Edwards KC, Blount BC, Caldwell KL, Feng J, Wang L, Christensen C, Ambrose B, Borek N, van Bemmel D, Konkel K, Erives G, Stanton CA, Lambert E, Kimmel HL, Hatsukami D, Hecht SS, Niaura RS, Travers M, Lawrence C, Hyland AJ.

JAMA Netw Open. 2018 Dec 7;1(8):e185937. doi: 10.1001/jamanetworkopen.2018.5937.

23.

Analysis of Acrolein-Derived 1, N2-Propanodeoxyguanosine Adducts in Human Lung DNA from Smokers and Nonsmokers.

Yang J, Balbo S, Villalta PW, Hecht SS.

Chem Res Toxicol. 2019 Feb 18;32(2):318-325. doi: 10.1021/acs.chemrestox.8b00326. Epub 2019 Jan 30.

24.

Prediagnostic levels of urinary 8-epi-prostaglandin F2α and prostaglandin E2 metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma.

Yuan JM, Grouls M, Carmella SG, Wang R, Heskin A, Jiang Y, Tan YT, Adams-Haduch J, Gao YT, Hecht SS.

Carcinogenesis. 2019 Aug 22;40(8):989-997. doi: 10.1093/carcin/bgy180.

PMID:
30615102
25.

Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein.

Chen M, Carmella SG, Sipe C, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami D, Hecht SS.

PLoS One. 2019 Jan 4;14(1):e0210104. doi: 10.1371/journal.pone.0210104. eCollection 2019.

26.

Urinary concentrations of monohydroxylated polycyclic aromatic hydrocarbons in adults from the U.S. Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013-2014).

Wang Y, Wong LY, Meng L, Pittman EN, Trinidad DA, Hubbard KL, Etheredge A, Del Valle-Pinero AY, Zamoiski R, van Bemmel DM, Borek N, Patel V, Kimmel HL, Conway KP, Lawrence C, Edwards KC, Hyland A, Goniewicz ML, Hatsukami D, Hecht SS, Calafat AM.

Environ Int. 2019 Feb;123:201-208. doi: 10.1016/j.envint.2018.11.068. Epub 2018 Dec 6.

27.

FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients.

Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Bastaki M, Davidsen JM, Harman CL, McGowen M, Taylor SV.

Food Chem Toxicol. 2019 Feb;124:192-218. doi: 10.1016/j.fct.2018.11.052. Epub 2018 Nov 24.

28.

Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial.

Hatsukami DK, Luo X, Jensen JA, al'Absi M, Allen SS, Carmella SG, Chen M, Cinciripini PM, Denlinger-Apte R, Drobes DJ, Koopmeiners JS, Lane T, Le CT, Leischow S, Luo K, McClernon FJ, Murphy SE, Paiano V, Robinson JD, Severson H, Sipe C, Strasser AA, Strayer LG, Tang MK, Vandrey R, Hecht SS, Benowitz NL, Donny EC.

JAMA. 2018 Sep 4;320(9):880-891. doi: 10.1001/jama.2018.11473.

29.

Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers.

Murphy SE, Park SL, Balbo S, Haiman CA, Hatsukami DK, Patel Y, Peterson LA, Stepanov I, Stram DO, Tretyakova N, Hecht SS, Le Marchand L.

NPJ Precis Oncol. 2018 Aug 22;2:17. doi: 10.1038/s41698-018-0057-y. eCollection 2018. Review.

30.

The safety evaluation of food flavouring substances: the role of metabolic studies.

Smith RL, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Guengerich FP, Rietjens IMCM, Bastaki M, Harman CL, McGowen MM, Taylor SV.

Toxicol Res (Camb). 2018 Mar 28;7(4):618-646. doi: 10.1039/c7tx00254h. eCollection 2018 Jul 1. Review.

31.

Relationship of the oxidative damage biomarker 8-epi-prostaglandin F2α to risk of lung cancer development in the Shanghai Cohort Study.

Yuan JM, Carmella SG, Wang R, Tan YT, Adams-Haduch J, Gao YT, Hecht SS.

Carcinogenesis. 2018 Jul 3;39(7):948-954. doi: 10.1093/carcin/bgy060.

PMID:
29726912
33.
34.

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food.

Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Davidsen JM, Harman CL, Taylor SV.

Food Chem Toxicol. 2018 Mar;113:171-178. doi: 10.1016/j.fct.2018.01.021. Epub 2018 Jan 31.

35.

A New Editorial Team for CRT.

Hecht SS.

Chem Res Toxicol. 2018 Jan 16;31(1):1. doi: 10.1021/acs.chemrestox.7b00318. Epub 2017 Dec 28. No abstract available.

PMID:
29283558
36.

Identification and analysis of a mercapturic acid conjugate of indole-3-methyl isothiocyanate in the urine of humans who consumed cruciferous vegetables.

Upadhyaya P, Zarth AT, Fujioka N, Fritz VA, Hecht SS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 1;1072:341-346. doi: 10.1016/j.jchromb.2017.12.001. Epub 2017 Dec 2.

37.

Identification of more than 100 structurally unique DNA-phosphate adducts formed during rat lung carcinogenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.

Carcinogenesis. 2018 Feb 9;39(2):232-241. doi: 10.1093/carcin/bgx135.

38.
39.

Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.

Chem Res Toxicol. 2018 Jan 16;31(1):48-57. doi: 10.1021/acs.chemrestox.7b00281. Epub 2017 Nov 30.

40.

Ultrasensitive High-Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung.

Villalta PW, Hochalter JB, Hecht SS.

Anal Chem. 2017 Dec 5;89(23):12735-12742. doi: 10.1021/acs.analchem.7b02856. Epub 2017 Nov 17.

41.

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s.

Carlson ES, Upadhyaya P, Hecht SS.

J Vis Exp. 2017 Sep 25;(127). doi: 10.3791/56312.

42.

Pilot in Vivo Structure-Activity Relationship of Dihydromethysticin in Blocking 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced O6-Methylguanine and Lung Tumor in A/J Mice.

Puppala M, Narayanapillai SC, Leitzman P, Sun H, Upadhyaya P, O'Sullivan MG, Hecht SS, Xing C.

J Med Chem. 2017 Sep 28;60(18):7935-7940. doi: 10.1021/acs.jmedchem.7b00921. Epub 2017 Sep 13.

43.

Investigation of the presence in human urine of mercapturic acids derived from phenanthrene, a representative polycyclic aromatic hydrocarbon.

Cheng G, Zarth AT, Upadhyaya P, Villalta PW, Balbo S, Hecht SS.

Chem Biol Interact. 2017 Aug 25;274:80-88. doi: 10.1016/j.cbi.2017.07.005. Epub 2017 Jul 8.

44.

High Level of Tobacco Carcinogen-Derived DNA Damage in Oral Cells Is an Independent Predictor of Oral/Head and Neck Cancer Risk in Smokers.

Khariwala SS, Ma B, Ruszczak C, Carmella SG, Lindgren B, Hatsukami DK, Hecht SS, Stepanov I.

Cancer Prev Res (Phila). 2017 Sep;10(9):507-513. doi: 10.1158/1940-6207.CAPR-17-0140. Epub 2017 Jul 5.

45.

Acrolein Exposure in Hookah Smokers and Non-Smokers Exposed to Hookah Tobacco Secondhand Smoke: Implications for Regulating Hookah Tobacco Products.

Kassem NOF, Kassem NO, Liles S, Zarth AT, Jackson SR, Daffa RM, Chatfield DA, Carmella SG, Hecht SS, Hovell MF.

Nicotine Tob Res. 2018 Mar 6;20(4):492-501. doi: 10.1093/ntr/ntx133.

46.

Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study.

Park SL, Murphy SE, Wilkens LR, Stram DO, Hecht SS, Le Marchand L.

PLoS One. 2017 May 25;12(5):e0178435. doi: 10.1371/journal.pone.0178435. eCollection 2017.

47.

Biomarkers of exposure to new and emerging tobacco delivery products.

Schick SF, Blount BC, Jacob P Rd, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L425-L452. doi: 10.1152/ajplung.00343.2016. Epub 2017 May 18. Review.

48.
49.

CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study.

Yuan JM, Nelson HH, Carmella SG, Wang R, Kuriger-Laber J, Jin A, Adams-Haduch J, Hecht SS, Koh WP, Murphy SE.

Carcinogenesis. 2017 Apr 1;38(4):411-418. doi: 10.1093/carcin/bgx012.

50.

Analysis of N'-nitrosonornicotine enantiomers in human urine by chiral stationary phase liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry.

Yang J, Carmella SG, Hecht SS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 15;1044-1045:127-131. doi: 10.1016/j.jchromb.2017.01.008. Epub 2017 Jan 9.

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