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Items: 1 to 50 of 691

1.

Oral Health Effects of Combusted and Smokeless Tobacco Products.

Tomar SL, Hecht SS, Jaspers I, Gregory RL, Stepanov I.

Adv Dent Res. 2019 Oct;30(1):4-10. doi: 10.1177/0022034519872480.

PMID:
31538806
2.

Differences in exposure to toxic and/or carcinogenic volatile organic compounds between Black and White cigarette smokers.

St Helen G, Benowitz NL, Ko J, Jacob P, Gregorich SE, Pérez-Stable EJ, Murphy SE, Hecht SS, Hatsukami DK, Donny EC.

J Expo Sci Environ Epidemiol. 2019 Aug 12. doi: 10.1038/s41370-019-0159-9. [Epub ahead of print]

PMID:
31406274
3.

A Randomized Clinical Trial of Snus Examining the Effect of Complete Versus Partial Cigarette Substitution on Smoking-Related Behaviors, and Biomarkers of Exposure.

Meier E, Lindgren BR, Anderson A, Reisinger SA, Norton KJ, Jensen J, Strayer L, Dick L, Tang MK, Chen M, Carmella SG, Hecht SS, Murphy SE, Yang J, Stepanov I, O'Connor RJ, Shields PG, Hatsukami DK.

Nicotine Tob Res. 2019 Apr 11. pii: ntz055. doi: 10.1093/ntr/ntz055. [Epub ahead of print]

PMID:
31321423
4.

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage.

McElroy JP, Carmella SG, Heskin AK, Tang MK, Murphy SE, Reisinger SA, Jensen JA, Hatsukami DK, Hecht SS, Shields PG.

PLoS One. 2019 Jun 28;14(6):e0218386. doi: 10.1371/journal.pone.0218386. eCollection 2019.

5.

Effects of immediate versus gradual nicotine reduction in cigarettes on biomarkers of biological effects.

Hatsukami DK, Luo X, Heskin AK, Tang MK, Carmella SG, Jensen J, Robinson JD, Vandrey R, Drobes DJ, Strasser AA, al'Absi M, Leischow S, Cinciripini PM, Koopmeiners J, Ikuemonisan J, Benowitz NL, Donny EC, Hecht SS.

Addiction. 2019 Oct;114(10):1824-1833. doi: 10.1111/add.14695. Epub 2019 Jul 8.

PMID:
31140663
6.

Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation.

Carmella SG, Heskin AK, Tang MK, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami DK, Hecht SS.

PLoS One. 2019 Apr 25;14(4):e0215853. doi: 10.1371/journal.pone.0215853. eCollection 2019.

7.

Recent Studies on DNA Adducts Resulting from Human Exposure to Tobacco Smoke.

Ma B, Stepanov I, Hecht SS.

Toxics. 2019 Mar 19;7(1). pii: E16. doi: 10.3390/toxics7010016. Review.

8.

Methyl DNA Phosphate Adduct Formation in Lung Tumor Tissue and Adjacent Normal Tissue of Lung Cancer Patients.

Ma B, Villalta PW, Hochalter JB, Stepanov I, Hecht SS.

Carcinogenesis. 2019 Mar 12. pii: bgz053. doi: 10.1093/carcin/bgz053. [Epub ahead of print]

PMID:
30873516
9.

Mass Spectrometric Quantitation of Pyridyloxobutyl DNA Phosphate Adducts in Rats Chronically Treated with N'-Nitrosonornicotine.

Li Y, Ma B, Cao Q, Balbo S, Zhao L, Upadhyaya P, Hecht SS.

Chem Res Toxicol. 2019 Apr 15;32(4):773-783. doi: 10.1021/acs.chemrestox.9b00007. Epub 2019 Feb 26.

PMID:
30740971
10.

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update.

Stram DO, Park SL, Haiman CA, Murphy SE, Patel Y, Hecht SS, Le Marchand L.

J Natl Cancer Inst. 2019 Jan 28. doi: 10.1093/jnci/djy206. [Epub ahead of print]

PMID:
30698722
11.

Comparison of Nicotine and Toxicant Exposure in Users of Electronic Cigarettes and Combustible Cigarettes.

Goniewicz ML, Smith DM, Edwards KC, Blount BC, Caldwell KL, Feng J, Wang L, Christensen C, Ambrose B, Borek N, van Bemmel D, Konkel K, Erives G, Stanton CA, Lambert E, Kimmel HL, Hatsukami D, Hecht SS, Niaura RS, Travers M, Lawrence C, Hyland AJ.

JAMA Netw Open. 2018 Dec 7;1(8):e185937. doi: 10.1001/jamanetworkopen.2018.5937.

12.

Analysis of Acrolein-Derived 1, N2-Propanodeoxyguanosine Adducts in Human Lung DNA from Smokers and Nonsmokers.

Yang J, Balbo S, Villalta PW, Hecht SS.

Chem Res Toxicol. 2019 Feb 18;32(2):318-325. doi: 10.1021/acs.chemrestox.8b00326. Epub 2019 Jan 30.

PMID:
30644728
13.

Prediagnostic levels of urinary 8-epi-prostaglandin F2α and prostaglandin E2 metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma.

Yuan JM, Grouls M, Carmella SG, Wang R, Heskin A, Jiang Y, Tan YT, Adams-Haduch J, Gao YT, Hecht SS.

Carcinogenesis. 2019 Aug 22;40(8):989-997. doi: 10.1093/carcin/bgy180.

PMID:
30615102
14.

Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein.

Chen M, Carmella SG, Sipe C, Jensen J, Luo X, Le CT, Murphy SE, Benowitz NL, McClernon FJ, Vandrey R, Allen SS, Denlinger-Apte R, Cinciripini PM, Strasser AA, al'Absi M, Robinson JD, Donny EC, Hatsukami D, Hecht SS.

PLoS One. 2019 Jan 4;14(1):e0210104. doi: 10.1371/journal.pone.0210104. eCollection 2019.

15.

Urinary concentrations of monohydroxylated polycyclic aromatic hydrocarbons in adults from the U.S. Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013-2014).

Wang Y, Wong LY, Meng L, Pittman EN, Trinidad DA, Hubbard KL, Etheredge A, Del Valle-Pinero AY, Zamoiski R, van Bemmel DM, Borek N, Patel V, Kimmel HL, Conway KP, Lawrence C, Edwards KC, Hyland A, Goniewicz ML, Hatsukami D, Hecht SS, Calafat AM.

Environ Int. 2019 Feb;123:201-208. doi: 10.1016/j.envint.2018.11.068. Epub 2018 Dec 6.

16.

FEMA GRAS assessment of natural flavor complexes: Citrus-derived flavoring ingredients.

Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Bastaki M, Davidsen JM, Harman CL, McGowen M, Taylor SV.

Food Chem Toxicol. 2019 Feb;124:192-218. doi: 10.1016/j.fct.2018.11.052. Epub 2018 Nov 24.

17.

Effect of Immediate vs Gradual Reduction in Nicotine Content of Cigarettes on Biomarkers of Smoke Exposure: A Randomized Clinical Trial.

Hatsukami DK, Luo X, Jensen JA, al'Absi M, Allen SS, Carmella SG, Chen M, Cinciripini PM, Denlinger-Apte R, Drobes DJ, Koopmeiners JS, Lane T, Le CT, Leischow S, Luo K, McClernon FJ, Murphy SE, Paiano V, Robinson JD, Severson H, Sipe C, Strasser AA, Strayer LG, Tang MK, Vandrey R, Hecht SS, Benowitz NL, Donny EC.

JAMA. 2018 Sep 4;320(9):880-891. doi: 10.1001/jama.2018.11473.

18.

Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers.

Murphy SE, Park SL, Balbo S, Haiman CA, Hatsukami DK, Patel Y, Peterson LA, Stepanov I, Stram DO, Tretyakova N, Hecht SS, Le Marchand L.

NPJ Precis Oncol. 2018 Aug 22;2:17. doi: 10.1038/s41698-018-0057-y. eCollection 2018. Review.

19.

The safety evaluation of food flavouring substances: the role of metabolic studies.

Smith RL, Cohen SM, Fukushima S, Gooderham NJ, Hecht SS, Guengerich FP, Rietjens IMCM, Bastaki M, Harman CL, McGowen MM, Taylor SV.

Toxicol Res (Camb). 2018 Mar 28;7(4):618-646. doi: 10.1039/c7tx00254h. eCollection 2018 Jul 1. Review.

20.

Relationship of the oxidative damage biomarker 8-epi-prostaglandin F2α to risk of lung cancer development in the Shanghai Cohort Study.

Yuan JM, Carmella SG, Wang R, Tan YT, Adams-Haduch J, Gao YT, Hecht SS.

Carcinogenesis. 2018 Jul 3;39(7):948-954. doi: 10.1093/carcin/bgy060.

PMID:
29726912
22.
23.

Updated procedure for the safety evaluation of natural flavor complexes used as ingredients in food.

Cohen SM, Eisenbrand G, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Davidsen JM, Harman CL, Taylor SV.

Food Chem Toxicol. 2018 Mar;113:171-178. doi: 10.1016/j.fct.2018.01.021. Epub 2018 Jan 31.

24.

A New Editorial Team for CRT.

Hecht SS.

Chem Res Toxicol. 2018 Jan 16;31(1):1. doi: 10.1021/acs.chemrestox.7b00318. Epub 2017 Dec 28. No abstract available.

PMID:
29283558
25.

Identification and analysis of a mercapturic acid conjugate of indole-3-methyl isothiocyanate in the urine of humans who consumed cruciferous vegetables.

Upadhyaya P, Zarth AT, Fujioka N, Fritz VA, Hecht SS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 1;1072:341-346. doi: 10.1016/j.jchromb.2017.12.001. Epub 2017 Dec 2.

26.

Identification of more than 100 structurally unique DNA-phosphate adducts formed during rat lung carcinogenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.

Carcinogenesis. 2018 Feb 9;39(2):232-241. doi: 10.1093/carcin/bgx135.

27.
28.

Methyl DNA Phosphate Adduct Formation in Rats Treated Chronically with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Ma B, Zarth AT, Carlson ES, Villalta PW, Upadhyaya P, Stepanov I, Hecht SS.

Chem Res Toxicol. 2018 Jan 16;31(1):48-57. doi: 10.1021/acs.chemrestox.7b00281. Epub 2017 Nov 30.

29.

Ultrasensitive High-Resolution Mass Spectrometric Analysis of a DNA Adduct of the Carcinogen Benzo[a]pyrene in Human Lung.

Villalta PW, Hochalter JB, Hecht SS.

Anal Chem. 2017 Dec 5;89(23):12735-12742. doi: 10.1021/acs.analchem.7b02856. Epub 2017 Nov 17.

30.

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s.

Carlson ES, Upadhyaya P, Hecht SS.

J Vis Exp. 2017 Sep 25;(127). doi: 10.3791/56312.

31.

Pilot in Vivo Structure-Activity Relationship of Dihydromethysticin in Blocking 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone-Induced O6-Methylguanine and Lung Tumor in A/J Mice.

Puppala M, Narayanapillai SC, Leitzman P, Sun H, Upadhyaya P, O'Sullivan MG, Hecht SS, Xing C.

J Med Chem. 2017 Sep 28;60(18):7935-7940. doi: 10.1021/acs.jmedchem.7b00921. Epub 2017 Sep 13.

32.

Investigation of the presence in human urine of mercapturic acids derived from phenanthrene, a representative polycyclic aromatic hydrocarbon.

Cheng G, Zarth AT, Upadhyaya P, Villalta PW, Balbo S, Hecht SS.

Chem Biol Interact. 2017 Aug 25;274:80-88. doi: 10.1016/j.cbi.2017.07.005. Epub 2017 Jul 8.

33.

High Level of Tobacco Carcinogen-Derived DNA Damage in Oral Cells Is an Independent Predictor of Oral/Head and Neck Cancer Risk in Smokers.

Khariwala SS, Ma B, Ruszczak C, Carmella SG, Lindgren B, Hatsukami DK, Hecht SS, Stepanov I.

Cancer Prev Res (Phila). 2017 Sep;10(9):507-513. doi: 10.1158/1940-6207.CAPR-17-0140. Epub 2017 Jul 5.

34.

Acrolein Exposure in Hookah Smokers and Non-Smokers Exposed to Hookah Tobacco Secondhand Smoke: Implications for Regulating Hookah Tobacco Products.

Kassem NOF, Kassem NO, Liles S, Zarth AT, Jackson SR, Daffa RM, Chatfield DA, Carmella SG, Hecht SS, Hovell MF.

Nicotine Tob Res. 2018 Mar 6;20(4):492-501. doi: 10.1093/ntr/ntx133.

35.

Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study.

Park SL, Murphy SE, Wilkens LR, Stram DO, Hecht SS, Le Marchand L.

PLoS One. 2017 May 25;12(5):e0178435. doi: 10.1371/journal.pone.0178435. eCollection 2017.

36.

Biomarkers of exposure to new and emerging tobacco delivery products.

Schick SF, Blount BC, Jacob P Rd, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L425-L452. doi: 10.1152/ajplung.00343.2016. Epub 2017 May 18. Review.

37.
38.

CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study.

Yuan JM, Nelson HH, Carmella SG, Wang R, Kuriger-Laber J, Jin A, Adams-Haduch J, Hecht SS, Koh WP, Murphy SE.

Carcinogenesis. 2017 Apr 1;38(4):411-418. doi: 10.1093/carcin/bgx012.

39.

Analysis of N'-nitrosonornicotine enantiomers in human urine by chiral stationary phase liquid chromatography-nanoelectrospray ionization-high resolution tandem mass spectrometry.

Yang J, Carmella SG, Hecht SS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 15;1044-1045:127-131. doi: 10.1016/j.jchromb.2017.01.008. Epub 2017 Jan 9.

40.

The Core Competencies for General Orthopaedic Surgeons.

Kellam JF, Archibald D, Barber JW, Christian EP, D'Ascoli RJ, Haynes RJ, Hecht SS, Hurwitz SR, Kellam JF, McLaren AC, Peabody TD, Southworth SR, Strauss RW, Wadey VM.

J Bone Joint Surg Am. 2017 Jan 18;99(2):175-181. doi: 10.2106/JBJS.16.00761.

PMID:
28099309
41.

Oral Cell DNA Adducts as Potential Biomarkers for Lung Cancer Susceptibility in Cigarette Smokers.

Hecht SS.

Chem Res Toxicol. 2017 Jan 17;30(1):367-375. doi: 10.1021/acs.chemrestox.6b00372. Epub 2016 Dec 1. Review.

42.

A Special Issue of CRT: Celebrating Volume 30.

Hecht SS.

Chem Res Toxicol. 2017 Jan 17;30(1):1. doi: 10.1021/acs.chemrestox.6b00440. No abstract available.

PMID:
28092940
43.

Tobacco, e-cigarettes, and child health.

Peterson LA, Hecht SS.

Curr Opin Pediatr. 2017 Apr;29(2):225-230. doi: 10.1097/MOP.0000000000000456. Review.

44.

Evaluation of Nitrosamide Formation in the Cytochrome P450-Mediated Metabolism of Tobacco-Specific Nitrosamines.

Carlson ES, Upadhyaya P, Hecht SS.

Chem Res Toxicol. 2016 Dec 19;29(12):2194-2205. Epub 2016 Dec 6.

45.

Safety evaluation of substituted thiophenes used as flavoring ingredients.

Cohen SM, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IM, Smith RL, Bastaki M, Harman CL, McGowen MM, Valerio LG, Taylor SV.

Food Chem Toxicol. 2017 Jan;99:40-59. doi: 10.1016/j.fct.2016.10.023. Epub 2016 Nov 9. Review.

46.

Reduced nicotine content cigarettes and use of alternative nicotine products: exploratory trial.

Hatsukami DK, Luo X, Dick L, Kangkum M, Allen SS, Murphy SE, Hecht SS, Shields PG, al'Absi M.

Addiction. 2017 Jan;112(1):156-167. doi: 10.1111/add.13603. Epub 2016 Nov 2.

47.

FEMA expert panel review of p-mentha-1,8-dien-7-al genotoxicity testing results.

Cohen SM, Fukushima S, Gooderham NJ, Guengerich FP, Hecht SS, Rietjens IMCM, Smith RL, Bastaki M, Harman CL, McGowen MM, Taylor SV.

Food Chem Toxicol. 2016 Dec;98(Pt B):201-209. doi: 10.1016/j.fct.2016.10.020. Epub 2016 Oct 20. Review.

48.

Harnessing the Power of Cruciferous Vegetables: Developing a Biomarker for Brassica Vegetable Consumption Using Urinary 3,3'-Diindolylmethane.

Fujioka N, Ransom BW, Carmella SG, Upadhyaya P, Lindgren BR, Roper-Batker A, Hatsukami DK, Fritz VA, Rohwer C, Hecht SS.

Cancer Prev Res (Phila). 2016 Oct;9(10):788-793. Epub 2016 Aug 18.

49.

Metabolites of the Polycyclic Aromatic Hydrocarbon Phenanthrene in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.

Patel YM, Park SL, Carmella SG, Paiano V, Olvera N, Stram DO, Haiman CA, Le Marchand L, Hecht SS.

PLoS One. 2016 Jun 8;11(6):e0156203. doi: 10.1371/journal.pone.0156203. eCollection 2016.

50.

A Randomized Controlled Trial of Progressively Reduced Nicotine Content Cigarettes on Smoking Behaviors, Biomarkers of Exposure, and Subjective Ratings.

Mercincavage M, Souprountchouk V, Tang KZ, Dumont RL, Wileyto EP, Carmella SG, Hecht SS, Strasser AA.

Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1125-33. doi: 10.1158/1055-9965.EPI-15-1088. Epub 2016 Apr 27.

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