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Single-cycle induction chemotherapy before chemoradiotherapy or surgery in functionally inoperable head and neck squamous cell carcinoma: 10-year results.

Breheret M, Lubgan D, Haderlein M, Hecht M, Traxdorf M, Schmidt D, Müller S, Kitzsteiner C, Kuwert T, Iro H, Fietkau R, Semrau S.

Eur Arch Otorhinolaryngol. 2019 Oct 3. doi: 10.1007/s00405-019-05665-5. [Epub ahead of print]


CD8+ and Regulatory T cells Differentiate Tumor Immune Phenotypes and Predict Survival in Locally Advanced Head and Neck Cancer.

Echarti A, Hecht M, Büttner-Herold M, Haderlein M, Hartmann A, Fietkau R, Distel L.

Cancers (Basel). 2019 Sep 19;11(9). pii: E1398. doi: 10.3390/cancers11091398.


Correlation of Parasite Burden, kDNA Integration, Autoreactive Antibodies, and Cytokine Pattern in the Pathophysiology of Chagas Disease.

Wesley M, Moraes A, Rosa AC, Lott Carvalho J, Shiroma T, Vital T, Dias N, de Carvalho B, do Amaral Rabello D, Borges TKDS, Dallago B, Nitz N, Hagström L, Hecht M.

Front Microbiol. 2019 Aug 21;10:1856. doi: 10.3389/fmicb.2019.01856. eCollection 2019.


The use of qPCR in human Chagas disease: a systematic review.

Hagström L, Marques ALP, Nitz N, Hecht MM.

Expert Rev Mol Diagn. 2019 Oct;19(10):875-894. doi: 10.1080/14737159.2019.1659729. Epub 2019 Sep 7.


Intestinal microbiota - A modulator of the Trypanosoma cruzi-vector-host triad.

Teotônio IMSN, Dias N, Hagström-Bex L, Nitz N, Francisco AF, Hecht M.

Microb Pathog. 2019 Sep 3;137:103711. doi: 10.1016/j.micpath.2019.103711. [Epub ahead of print] Review.


[Stereotactic ablative radiotherapy confirmed as a standard technique in NSCLC stage I].

Hecht M, Fietkau R.

Strahlenther Onkol. 2019 Oct;195(10):945-948. doi: 10.1007/s00066-019-01503-z. German. No abstract available.


"Choose Today, Live Tomorrow": A Content Analysis of Anti-Substance Use Messages Produced by Adolescents.

Peña-Alves S, Greene K, Ray AE, Glenn SD, Hecht ML, Banerjee SC.

J Health Commun. 2019 Jul 15:1-11. doi: 10.1080/10810730.2019.1639858. [Epub ahead of print]


Photoconductive Core-Shell Liquid-Crystals of a Perylene Bisimide J-Aggregate Donor-Acceptor Dyad.

Hecht M, Schlossarek T, Stolte M, Lehmann M, Würthner F.

Angew Chem Int Ed Engl. 2019 Sep 9;58(37):12979-12983. doi: 10.1002/anie.201904789. Epub 2019 Jul 19.


An E-Learning Adaptation of an Evidence-Based Media Literacy Curriculum to Prevent Youth Substance Use in Community Groups: Development and Feasibility of REAL Media.

Ray AE, Greene K, Hecht ML, Barriage SC, Miller-Day M, Glenn SD, Banerjee SC.

JMIR Form Res. 2019 May 9;3(2):e12132. doi: 10.2196/12132.


Salivary gland carcinoma (SGC) with perineural spread and/or positive resection margin - high locoregional control rates after photon (chemo) radiotherapy - experience from a monocentric analysis.

Haderlein M, Scherl C, Semrau S, Lettmaier S, Hecht M, Putz F, Iro H, Agaimy A, Fietkau R.

Radiat Oncol. 2019 Apr 23;14(1):68. doi: 10.1186/s13014-019-1260-x.


Variability in content and dissolution profiles of MDMA tablets collected in the UK between 2001 and 2018 - A potential risk to users?

Couchman L, Frinculescu A, Sobreira C, Shine T, Ramsey J, Hecht M, Kipper K, Holt D, Johnston A.

Drug Test Anal. 2019 Aug;11(8):1172-1182. doi: 10.1002/dta.2605. Epub 2019 May 15.


Bayesian continuous-time Rasch models.

Hecht M, Hardt K, Driver CC, Voelkle MC.

Psychol Methods. 2019 Aug;24(4):516-537. doi: 10.1037/met0000205. Epub 2019 Apr 22.


An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry.

Hecht M, Rösler R, Wiese S, Johnsson N, Gronemeyer T.

G3 (Bethesda). 2019 Jun 5;9(6):1869-1880. doi: 10.1534/g3.119.400197.


Initial Evaluation of Pain Intensity Among Depressed Patients as a Possible Mediator Between Depression and Pain Complaints.

Nitzan U, Hecht M, Braw Y, Maoz H, Levkovitz Y, Yarnitsky D, Granovsky Y, Bloch Y.

Front Psychiatry. 2019 Feb 15;10:48. doi: 10.3389/fpsyt.2019.00048. eCollection 2019.


Congenital Chagas disease: alert of research negligence.

Dias N, Carvalho B, Nitz N, Hagström L, Vital T, Hecht M.

Rev Soc Bras Med Trop. 2019 Feb 21;52:e20180069. doi: 10.1590/0037-8682-0069-2018.


Improving the reference standard for the diagnosis of canine visceral leishmaniasis: a challenge for current and future tests.

Teixeira AIP, Silva DM, Vital T, Nitz N, de Carvalho BC, Hecht M, Oliveira D, Oliveira E, Rabello A, Romero GAS.

Mem Inst Oswaldo Cruz. 2019 Jan 31;114:e180452. doi: 10.1590/0074-02760180452.


IFNG-AS1 Enhances Interferon Gamma Production in Human Natural Killer Cells.

Stein N, Berhani O, Schmiedel D, Duev-Cohen A, Seidel E, Kol I, Tsukerman P, Hecht M, Reches A, Gamliel M, Obeidat A, Charpak-Amikam Y, Yamin R, Mandelboim O.

iScience. 2019 Jan 25;11:466-473. doi: 10.1016/j.isci.2018.12.034. Epub 2019 Jan 3.


Unevolved De Novo Proteins Have Innate Tendencies to Bind Transition Metals.

Wang MS, Hoegler KJ, Hecht MH.

Life (Basel). 2019 Jan 9;9(1). pii: E8. doi: 10.3390/life9010008.


Mix-&-Read Determination of Mercury(II) at Trace Levels with Hybrid Mesoporous Silica Materials Incorporating Fluorescent Probes by a Simple Mix-&-Load Technique.

Climent E, Hecht M, Witthuhn H, Gawlitza K, Rurack K.

ChemistryOpen. 2018 Dec 3;7(12):933. doi: 10.1002/open.201800231. eCollection 2018 Dec.


Mix-&-Read Determination of Mercury(II) at Trace Levels with Hybrid Mesoporous Silica Materials Incorporating Fluorescent Probes by a Simple Mix-&-Load Technique.

Climent E, Hecht M, Witthuhn H, Gawlitza K, Rurack K.

ChemistryOpen. 2018 Dec 5;7(12):957-968. doi: 10.1002/open.201800277. eCollection 2018 Dec.


The first Acanthamoeba keratitis case in the Midwest region of Brazil: diagnosis, genotyping of the parasite and disease outcome.

Alves DSMM, Gonçalves GS, Moraes AS, Alves LM, Carmo Neto JRD, Hecht MM, Nitz N, Gurgel-Gonçalves R, Bernardes G, Castro AM, Chalita MR, Vinaud MC.

Rev Soc Bras Med Trop. 2018 Sep-Oct;51(5):716-719. doi: 10.1590/0037-8682-0010-2018.


A CRISPR/Cas9 platform for MS2-labelling of single mRNA in live stem cells.

Spille JH, Hecht M, Grube V, Cho WK, Lee C, Cissé II.

Methods. 2019 Jan 15;153:35-45. doi: 10.1016/j.ymeth.2018.09.004. Epub 2018 Sep 12.


Mix-&-Read Determination of Mercury(II) at Trace Levels with Hybrid Mesoporous Silica Materials Incorporating Fluorescent Probes by a Simple Mix-&-Load Technique.

Climent E, Hecht M, Witthuhn H, Gawlitza K, Rurack K.

ChemistryOpen. 2018 Sep 10;7(9):709-720. doi: 10.1002/open.201800111. eCollection 2018 Sep.


Newly diagnosed AIDS with neurosyphilis, Kaposi sarcoma, pancytopenia, oropharyngeal candidiasis, and pseudomonal pneumonia: We shouldn't be seeing this anymore.

Yunina DS, Elkayam N, Patel S, Okoli F, Chapnick E, Hecht M.

IDCases. 2018 Jul 12;13:e00426. doi: 10.1016/j.idcr.2018.e00426. eCollection 2018.


High molecular prevalence of Leishmania in phlebotomine sand flies fed on chicken blood in Brazil.

de Sousa Ferreira T, Timbó RV, Minuzzi-Souza TTC, de Almeida Rocha D, Neiva M, de Albuquerque Ribeiro J, de Almeida PS, Hecht M, Nitz N, Gurgel-Gonçalves R.

Vet Parasitol. 2018 Aug 15;259:80-84. doi: 10.1016/j.vetpar.2018.07.004. Epub 2018 Jul 7.


Designed Cultural Adaptation and Delivery Quality in Rural Substance Use Prevention: an Effectiveness Trial for the Keepin' it REAL Curriculum.

Hecht ML, Shin Y, Pettigrew J, Miller-Day M, Krieger JL.

Prev Sci. 2018 Nov;19(8):1008-1018. doi: 10.1007/s11121-018-0937-y.


From Face-to-Face to Facebook: Probing the Effects of Passive Consumption on Interpersonal Attraction.

Orben AC, Mutak A, Dablander F, Hecht M, Krawiec JM, Valkovičová N, Kosīte D.

Front Psychol. 2018 Jul 10;9:1163. doi: 10.3389/fpsyg.2018.01163. eCollection 2018.


Utilization of data below the analytical limit of quantitation in pharmacokinetic analysis and modeling: promoting interdisciplinary debate.

Hecht M, Veigure R, Couchman L, S Barker CI, Standing JF, Takkis K, Evard H, Johnston A, Herodes K, Leito I, Kipper K.

Bioanalysis. 2018 Aug 1;10(15):1229-1248. doi: 10.4155/bio-2018-0078. Epub 2018 Jul 23.


Molecular bloodmeal analyses reveal that Trypanosoma cruzi-infected, native triatomine bugs often feed on humans in houses in central Brazil.

Minuzzi-Souza TTC, Silva LR, Hagström L, Hecht M, Nitz N, Gurgel-Gonçalves R.

Med Vet Entomol. 2018 Dec;32(4):504-508. doi: 10.1111/mve.12324. Epub 2018 Jul 12.


Repeating of local therapy of distant metastases increases overall survival in patients with synchronous metastasized rectal cancer-a monocentric analysis.

Haderlein M, Lettmaier S, Langheinrich M, Schmid A, Semrau S, Hecht M, Beck M, Schmidt D, Grützmann R, Fietkau R, Denz A.

Int J Colorectal Dis. 2018 Nov;33(11):1533-1541. doi: 10.1007/s00384-018-3113-8. Epub 2018 Jul 2.


Mediator and RNA polymerase II clusters associate in transcription-dependent condensates.

Cho WK, Spille JH, Hecht M, Lee C, Li C, Grube V, Cisse II.

Science. 2018 Jul 27;361(6400):412-415. doi: 10.1126/science.aar4199. Epub 2018 Jun 21.


Rate of individuals with clearly increased radiosensitivity rise with age both in healthy individuals and in cancer patients.

Schuster B, Ellmann A, Mayo T, Auer J, Haas M, Hecht M, Fietkau R, Distel LV.

BMC Geriatr. 2018 May 4;18(1):105. doi: 10.1186/s12877-018-0799-y.


Author Correction: Surveillance of vector-borne pathogens under imperfect detection: lessons from Chagas disease risk (mis)measurement.

Minuzzi-Souza TTC, Nitz N, Cuba CAC, Hagström L, Hecht MM, Santana C, Ribeiro M, Vital TE, Santalucia M, Knox M, Obara MT, Abad-Franch F, Gurgel-Gonçalves R.

Sci Rep. 2018 May 4;8(1):7439. doi: 10.1038/s41598-018-24849-3.


Self-Assembling Supramolecular Nanostructures Constructed from de Novo Extender Protein Nanobuilding Blocks.

Kobayashi N, Inano K, Sasahara K, Sato T, Miyazawa K, Fukuma T, Hecht MH, Song C, Murata K, Arai R.

ACS Synth Biol. 2018 May 18;7(5):1381-1394. doi: 10.1021/acssynbio.8b00007. Epub 2018 May 8.


Capillary cerebral amyloid angiopathy in Alzheimer's disease: association with allocortical/hippocampal microinfarcts and cognitive decline.

Hecht M, Krämer LM, von Arnim CAF, Otto M, Thal DR.

Acta Neuropathol. 2018 May;135(5):681-694. doi: 10.1007/s00401-018-1834-y. Epub 2018 Mar 24.


Immune modulatory effects of radiotherapy as basis for well-reasoned radioimmunotherapies.

Rückert M, Deloch L, Fietkau R, Frey B, Hecht M, Gaipl US.

Strahlenther Onkol. 2018 Jun;194(6):509-519. doi: 10.1007/s00066-018-1287-1. Epub 2018 Mar 2. Review.


Trends of Parent-Adolescent Drug Talk Styles in Early Adolescence.

Shin Y, Pettigrew J, Miller-Day M, Hecht ML, Krieger JL.

Health Commun. 2019 Jul;34(8):801-810. doi: 10.1080/10410236.2018.1437522. Epub 2018 Feb 20.


Differential Effects of Parental "drug talk" Styles and Family Communication Environments on Adolescent Substance Use.

Shin Y, Miller-Day M, Hecht ML.

Health Commun. 2019 Jul;34(8):872-880. doi: 10.1080/10410236.2018.1439268. Epub 2018 Feb 20.


Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients.

Hecht M, Meier F, Zimmer L, Polat B, Loquai C, Weishaupt C, Forschner A, Gutzmer R, Utikal JS, Goldinger SM, Geier M, Hassel JC, Balermpas P, Kiecker F, Rauschenberg R, Dietrich U, Clemens P, Berking C, Grabenbauer G, Schadendorf D, Grabbe S, Schuler G, Fietkau R, Distel LV, Heinzerling L.

Br J Cancer. 2018 Mar 20;118(6):785-792. doi: 10.1038/bjc.2017.489. Epub 2018 Feb 13.


Cytotoxic effect of Efavirenz in BxPC-3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation.

Hecht M, Harrer T, Körber V, Sarpong EO, Moser F, Fiebig N, Schwegler M, Stürzl M, Fietkau R, Distel LV.

Oncol Lett. 2018 Feb;15(2):1728-1736. doi: 10.3892/ol.2017.7523. Epub 2017 Dec 5.


Taking an HPV vaccine research-tested intervention to scale in a clinical setting.

Hopfer S, Ray AE, Hecht ML, Miller-Day M, Belue R, Zimet G, Evans WD, McKee FX.

Transl Behav Med. 2018 Sep 8;8(5):745-752. doi: 10.1093/tbm/ibx066.


[Durvalumab improves prognosis of stage III non-small-cell lung cancer after definitive chemoradiotherapy].

Hecht M, Gaipl US, Fietkau R.

Strahlenther Onkol. 2018 Mar;194(3):269-271. doi: 10.1007/s00066-017-1253-3. German. No abstract available.


Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity.

Hoegler KJ, Hecht MH.

J Mol Evol. 2018 Feb;86(2):103-110. doi: 10.1007/s00239-018-9830-3. Epub 2018 Jan 22.


Synanthropic triatomines as potential vectors of Trypanosoma cruzi in Central Brazil.

Minuzzi-Souza TTC, Nitz N, Cuba CAC, Santalucia M, Knox M, Hagström L, Furtado CB, Vital TE, Obara MT, Hecht MM, Gurgel-Gonçalves R.

Rev Soc Bras Med Trop. 2017 Nov-Dec;50(6):824-828. doi: 10.1590/0037-8682-0199-2017.


A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli.

Donnelly AE, Murphy GS, Digianantonio KM, Hecht MH.

Nat Chem Biol. 2018 Mar;14(3):253-255. doi: 10.1038/nchembio.2550. Epub 2018 Jan 15.


Surveillance of vector-borne pathogens under imperfect detection: lessons from Chagas disease risk (mis)measurement.

Minuzzi-Souza TTC, Nitz N, Cuba CAC, Hagström L, Hecht MM, Santana C, Ribeiro M, Vital TE, Santalucia M, Knox M, Obara MT, Abad-Franch F, Gurgel-Gonçalves R.

Sci Rep. 2018 Jan 9;8(1):151. doi: 10.1038/s41598-017-18532-2. Erratum in: Sci Rep. 2018 May 4;8(1):7439.


Are natural proteins special? Can we do that?

Hecht MH, Zarzhitsky S, Karas C, Chari S.

Curr Opin Struct Biol. 2018 Feb;48:124-132. doi: 10.1016/ Epub 2018 Jan 3. Review.


Targeted On-line SPE-LC-MS/MS Assay for the Quantitation of 12 Apolipoproteins from Human Blood.

Dittrich J, Adam M, Maas H, Hecht M, Reinicke M, Ruhaak LR, Cobbaert C, Engel C, Wirkner K, Löffler M, Thiery J, Ceglarek U.

Proteomics. 2018 Feb;18(3-4). doi: 10.1002/pmic.201700279. Epub 2018 Feb 2.


Can sexual transmission support the enzootic cycle of Trypanosoma cruzi?

Rios A, Ribeiro M, Sousa A, Pimentel F, Hagström L, Andrade R, Alves RM, Rosa AC, Teixeira AR, Nitz N, Hecht MM.

Mem Inst Oswaldo Cruz. 2018 Jan;113(1):3-8. doi: 10.1590/0074-02760170025.

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