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Items: 5

1.

Caveolin-1 regulates TCR signal strength and regulatory T-cell differentiation into alloreactive T cells.

Schönle A, Hartl FA, Mentzel J, Nöltner T, Rauch KS, Prestipino A, Wohlfeil SA, Apostolova P, Hechinger AK, Melchinger W, Fehrenbach K, Guadamillas MC, Follo M, Prinz G, Ruess AK, Pfeifer D, del Pozo MA, Schmitt-Graeff A, Duyster J, Hippen KI, Blazar BR, Schachtrup K, Minguet S, Zeiser R.

Blood. 2016 Apr 14;127(15):1930-9. doi: 10.1182/blood-2015-09-672428. Epub 2016 Feb 2.

2.

Therapeutic activity of multiple common γ-chain cytokine inhibition in acute and chronic GVHD.

Hechinger AK, Smith BA, Flynn R, Hanke K, McDonald-Hyman C, Taylor PA, Pfeifer D, Hackanson B, Leonhardt F, Prinz G, Dierbach H, Schmitt-Graeff A, Kovarik J, Blazar BR, Zeiser R.

Blood. 2015 Jan 15;125(3):570-80. doi: 10.1182/blood-2014-06-581793. Epub 2014 Oct 28.

3.

Inflammatory neovascularization during graft-versus-host disease is regulated by αv integrin and miR-100.

Leonhardt F, Grundmann S, Behe M, Bluhm F, Dumont RA, Braun F, Fani M, Riesner K, Prinz G, Hechinger AK, Gerlach UV, Dierbach H, Penack O, Schmitt-Gräff A, Finke J, Weber WA, Zeiser R.

Blood. 2013 Apr 25;121(17):3307-18. doi: 10.1182/blood-2012-07-442665. Epub 2013 Jan 17.

4.

Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells.

Hechinger AK, Maas K, Dürr C, Leonhardt F, Prinz G, Marks R, Gerlach U, Hofmann M, Fisch P, Finke J, Pircher H, Zeiser R.

Haematologica. 2013 Jan;98(1):31-40. doi: 10.3324/haematol.2012.065789. Epub 2012 Jul 16.

5.

Spleen tyrosine kinase (Syk) is a potent target for GvHD prevention at different cellular levels.

Leonhardt F, Zirlik K, Buchner M, Prinz G, Hechinger AK, Gerlach UV, Fisch P, Schmitt-Gräff A, Reichardt W, Zeiser R.

Leukemia. 2012 Jul;26(7):1617-29. doi: 10.1038/leu.2012.10. Epub 2012 Jan 17.

PMID:
22301676

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