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Items: 1 to 50 of 92

1.

Transient Redirection of SVZ Stem Cells to Oligodendrogenesis by FGFR3 Activation Promotes Remyelination.

Kang W, Nguyen KCQ, Hébert JM.

Stem Cell Reports. 2019 Jun 11;12(6):1223-1231. doi: 10.1016/j.stemcr.2019.05.006.

2.

A Robust Method for the Purification and Characterization of Recombinant Human Histone H1 Variants.

Osunsade A, Prescott NA, Hebert JM, Ray DM, Jmeian Y, Lorenz IC, David Y.

Biochemistry. 2019 Jan 22;58(3):171-176. doi: 10.1021/acs.biochem.8b01060. Epub 2019 Jan 8.

PMID:
30585724
3.

Cell Replacement to Reverse Brain Aging: Challenges, Pitfalls, and Opportunities.

Hébert JM, Vijg J.

Trends Neurosci. 2018 May;41(5):267-279. doi: 10.1016/j.tins.2018.02.008. Epub 2018 Mar 13. Review.

4.

Early uneven ear input induces long-lasting differences in left-right motor function.

Antoine MW, Zhu X, Dieterich M, Brandt T, Vijayakumar S, McKeehan N, Arezzo JC, Zukin RS, Borkholder DA, Jones SM, Frisina RD, Hébert JM.

PLoS Biol. 2018 Mar 13;16(3):e2002988. doi: 10.1371/journal.pbio.2002988. eCollection 2018 Mar.

5.

Neurotrophin and FGF Signaling Adapter Proteins, FRS2 and FRS3, Regulate Dentate Granule Cell Maturation and Excitatory Synaptogenesis.

Nandi S, Alviña K, Lituma PJ, Castillo PE, Hébert JM.

Neuroscience. 2018 Jan 15;369:192-201. doi: 10.1016/j.neuroscience.2017.11.017. Epub 2017 Nov 16.

6.

FGF-Dependent, Context-Driven Role for FRS Adapters in the Early Telencephalon.

Nandi S, Gutin G, Blackwood CA, Kamatkar NG, Lee KW, Fishell G, Wang F, Goldfarb M, Hébert JM.

J Neurosci. 2017 Jun 7;37(23):5690-5698. doi: 10.1523/JNEUROSCI.2931-16.2017. Epub 2017 May 8.

7.

The Severity of Vestibular Dysfunction in Deafness as a Determinant of Comorbid Hyperactivity or Anxiety.

Antoine MW, Vijayakumar S, McKeehan N, Jones SM, Hébert JM.

J Neurosci. 2017 May 17;37(20):5144-5154. doi: 10.1523/JNEUROSCI.3545-16.2017. Epub 2017 Apr 24.

8.

Roles for small noncoding RNAs in silencing of retrotransposons in the mammalian brain.

Nandi S, Chandramohan D, Fioriti L, Melnick AM, Hébert JM, Mason CE, Rajasethupathy P, Kandel ER.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12697-12702. doi: 10.1073/pnas.1609287113. Epub 2016 Oct 24.

9.

Whole chromosome aneuploidy in the brain of Bub1bH/H and Ercc1-/Δ7 mice.

Andriani GA, Faggioli F, Baker D, Dollé ME, Sellers RS, Hébert JM, Van Steeg H, Hoeijmakers J, Vijg J, Montagna C.

Hum Mol Genet. 2016 Feb 15;25(4):755-65. doi: 10.1093/hmg/ddv612. Epub 2015 Dec 17.

10.

FGF Signaling Is Necessary for Neurogenesis in Young Mice and Sufficient to Reverse Its Decline in Old Mice.

Kang W, Hébert JM.

J Neurosci. 2015 Jul 15;35(28):10217-23. doi: 10.1523/JNEUROSCI.1469-15.2015.

11.

Chemical investigation of the medicinal and ornamental plant Angelonia angustifolia Benth. reveals therapeutic quantities of lupeol.

Deyrup ST, Asghar KB, Chacko A, Hebert JM, Samson E, Talone CJ.

Fitoterapia. 2014 Oct;98:174-8. doi: 10.1016/j.fitote.2014.08.005. Epub 2014 Aug 10.

PMID:
25111011
12.

Astrocyte activation is suppressed in both normal and injured brain by FGF signaling.

Kang W, Balordi F, Su N, Chen L, Fishell G, Hébert JM.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2987-95. doi: 10.1073/pnas.1320401111. Epub 2014 Jul 7.

13.

CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations.

Province MA, Goetz MP, Brauch H, Flockhart DA, Hebert JM, Whaley R, Suman VJ, Schroth W, Winter S, Zembutsu H, Mushiroda T, Newman WG, Lee MT, Ambrosone CB, Beckmann MW, Choi JY, Dieudonné AS, Fasching PA, Ferraldeschi R, Gong L, Haschke-Becher E, Howell A, Jordan LB, Hamann U, Kiyotani K, Krippl P, Lambrechts D, Latif A, Langsenlehner U, Lorizio W, Neven P, Nguyen AT, Park BW, Purdie CA, Quinlan P, Renner W, Schmidt M, Schwab M, Shin JG, Stingl JC, Wegman P, Wingren S, Wu AH, Ziv E, Zirpoli G, Thompson AM, Jordan VC, Nakamura Y, Altman RB, Ames MM, Weinshilboum RM, Eichelbaum M, Ingle JN, Klein TE; International Tamoxifen Pharmacogenomics Consortium.

Clin Pharmacol Ther. 2014 Feb;95(2):216-27. doi: 10.1038/clpt.2013.186. Epub 2013 Sep 23.

14.

A causative link between inner ear defects and long-term striatal dysfunction.

Antoine MW, Hübner CA, Arezzo JC, Hébert JM.

Science. 2013 Sep 6;341(6150):1120-3. doi: 10.1126/science.1240405.

15.

PharmGKB summary: very important pharmacogene information for the epidermal growth factor receptor.

Hodoglugil U, Carrillo MW, Hebert JM, Karachaliou N, Rosell RC, Altman RB, Klein TE.

Pharmacogenet Genomics. 2013 Nov;23(11):636-42. doi: 10.1097/FPC.0b013e3283655091. Review. No abstract available.

16.

Only scratching the cell surface: extracellular signals in cerebrum development.

Hébert JM.

Curr Opin Genet Dev. 2013 Aug;23(4):470-4. doi: 10.1016/j.gde.2013.04.004. Epub 2013 May 10. Review.

17.

Apoptosis of glutamatergic neurons fails to trigger a neurogenic response in the adult neocortex.

Diaz F, McKeehan N, Kang W, Hébert JM.

J Neurosci. 2013 Apr 10;33(15):6278-84. doi: 10.1523/JNEUROSCI.5885-12.2013.

18.

Nomenclature for alleles of the thiopurine methyltransferase gene.

Appell ML, Berg J, Duley J, Evans WE, Kennedy MA, Lennard L, Marinaki T, McLeod HL, Relling MV, Schaeffeler E, Schwab M, Weinshilboum R, Yeoh AE, McDonagh EM, Hebert JM, Klein TE, Coulthard SA.

Pharmacogenet Genomics. 2013 Apr;23(4):242-8. doi: 10.1097/FPC.0b013e32835f1cc0.

19.

A Sox2 BAC transgenic approach for targeting adult neural stem cells.

Kang W, Hébert JM.

PLoS One. 2012;7(11):e49038. doi: 10.1371/journal.pone.0049038. Epub 2012 Nov 7.

20.

Pharmacogenomics knowledge for personalized medicine.

Whirl-Carrillo M, McDonagh EM, Hebert JM, Gong L, Sangkuhl K, Thorn CF, Altman RB, Klein TE.

Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96. Review.

21.

Central nervous system malformations and deformations in FGFR2-related craniosynostosis.

Khonsari RH, Delezoide AL, Kang W, Hébert JM, Bessières B, Bodiguel V, Collet C, Legeai-Mallet L, Sharpe PT, Fallet-Bianco C.

Am J Med Genet A. 2012 Nov;158A(11):2797-806. doi: 10.1002/ajmg.a.35598. Epub 2012 Sep 17.

PMID:
22987770
22.

Using ODIN for a PharmGKB revalidation experiment.

Rinaldi F, Clematide S, Garten Y, Whirl-Carrillo M, Gong L, Hebert JM, Sangkuhl K, Thorn CF, Klein TE, Altman RB.

Database (Oxford). 2012 Apr 23;2012:bas021. doi: 10.1093/database/bas021. Print 2012.

23.

PharmGKB summary: very important pharmacogene information for CYP3A5.

Lamba J, Hebert JM, Schuetz EG, Klein TE, Altman RB.

Pharmacogenet Genomics. 2012 Jul;22(7):555-8. doi: 10.1097/FPC.0b013e328351d47f. No abstract available.

24.

SMAD4 is essential for generating subtypes of neurons during cerebellar development.

Fernandes M, Antoine M, Hébert JM.

Dev Biol. 2012 May 1;365(1):82-90. doi: 10.1016/j.ydbio.2012.02.017. Epub 2012 Feb 18.

25.

FGFs: Neurodevelopment's Jack-of-all-Trades - How Do They Do it?

Hébert JM.

Front Neurosci. 2011 Dec 5;5:133. doi: 10.3389/fnins.2011.00133. eCollection 2011.

26.

Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics.

Paek H, Antoine MW, Diaz F, Hébert JM.

Dev Dyn. 2012 Feb;241(2):242-6. doi: 10.1002/dvdy.22787. Epub 2011 Nov 18.

27.

A conserved Pbx-Wnt-p63-Irf6 regulatory module controls face morphogenesis by promoting epithelial apoptosis.

Ferretti E, Li B, Zewdu R, Wells V, Hebert JM, Karner C, Anderson MJ, Williams T, Dixon J, Dixon MJ, Depew MJ, Selleri L.

Dev Cell. 2011 Oct 18;21(4):627-41. doi: 10.1016/j.devcel.2011.08.005. Epub 2011 Oct 6.

28.

Phased whole-genome genetic risk in a family quartet using a major allele reference sequence.

Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, Thorn CF, Hebert JM, Capriotti E, David SP, Pavlovic A, West A, Thakuria JV, Ball MP, Zaranek AW, Rehm HL, Church GM, West JS, Bustamante CD, Snyder M, Altman RB, Klein TE, Butte AJ, Ashley EA.

PLoS Genet. 2011 Sep;7(9):e1002280. doi: 10.1371/journal.pgen.1002280. Epub 2011 Sep 15.

29.

β-Catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4.

Paek H, Hwang JY, Zukin RS, Hébert JM.

Dev Cell. 2011 May 17;20(5):689-99. doi: 10.1016/j.devcel.2011.04.010.

30.

Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain.

Furusho M, Kaga Y, Ishii A, Hébert JM, Bansal R.

J Neurosci. 2011 Mar 30;31(13):5055-66. doi: 10.1523/JNEUROSCI.4800-10.2011.

31.

Signaling pathways in reactive astrocytes, a genetic perspective.

Kang W, Hébert JM.

Mol Neurobiol. 2011 Jun;43(3):147-54. doi: 10.1007/s12035-011-8163-7. Epub 2011 Jan 14. Review.

32.

Clinical assessment incorporating a personal genome.

Ashley EA, Butte AJ, Wheeler MT, Chen R, Klein TE, Dewey FE, Dudley JT, Ormond KE, Pavlovic A, Morgan AA, Pushkarev D, Neff NF, Hudgins L, Gong L, Hodges LM, Berlin DS, Thorn CF, Sangkuhl K, Hebert JM, Woon M, Sagreiya H, Whaley R, Knowles JW, Chou MF, Thakuria JV, Rosenbaum AM, Zaranek AW, Church GM, Greely HT, Quake SR, Altman RB.

Lancet. 2010 May 1;375(9725):1525-35. doi: 10.1016/S0140-6736(10)60452-7.

33.

Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates.

Maier E, von Hofsten J, Nord H, Fernandes M, Paek H, Hébert JM, Gunhaga L.

Development. 2010 May;137(10):1601-11. doi: 10.1242/dev.051219. Epub 2010 Apr 14.

34.

Very important pharmacogene summary: thiopurine S-methyltransferase.

Wang L, Pelleymounter L, Weinshilboum R, Johnson JA, Hebert JM, Altman RB, Klein TE.

Pharmacogenet Genomics. 2010 Jun;20(6):401-5. doi: 10.1097/FPC.0b013e3283352860. Review. No abstract available.

35.

Thiopurine pathway.

Zaza G, Cheok M, Krynetskaia N, Thorn C, Stocco G, Hebert JM, McLeod H, Weinshilboum RM, Relling MV, Evans WE, Klein TE, Altman RB.

Pharmacogenet Genomics. 2010 Sep;20(9):573-4. doi: 10.1097/FPC.0b013e328334338f. No abstract available.

36.

The transition from radial glial to intermediate progenitor cell is inhibited by FGF signaling during corticogenesis.

Kang W, Wong LC, Shi SH, Hébert JM.

J Neurosci. 2009 Nov 18;29(46):14571-80. doi: 10.1523/JNEUROSCI.3844-09.2009.

37.

FGF signaling is strictly required to maintain early telencephalic precursor cell survival.

Paek H, Gutin G, Hébert JM.

Development. 2009 Jul;136(14):2457-65. doi: 10.1242/dev.032656.

38.

The genetics of early telencephalon patterning: some assembly required.

Hébert JM, Fishell G.

Nat Rev Neurosci. 2008 Sep;9(9):678-85. doi: 10.1038/nrn2463. Review.

39.

Early forebrain wiring: genetic dissection using conditional Celsr3 mutant mice.

Zhou L, Bar I, Achouri Y, Campbell K, De Backer O, Hebert JM, Jones K, Kessaris N, de Rouvroit CL, O'Leary D, Richardson WD, Goffinet AM, Tissir F.

Science. 2008 May 16;320(5878):946-9. doi: 10.1126/science.1155244.

40.

The ups and downs of holoprosencephaly: dorsal versus ventral patterning forces.

Fernandes M, Hébert JM.

Clin Genet. 2008 May;73(5):413-23. doi: 10.1111/j.1399-0004.2008.00994.x. Epub 2008 Apr 2. Review.

PMID:
18394003
41.

The pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge.

Hernandez-Boussard T, Whirl-Carrillo M, Hebert JM, Gong L, Owen R, Gong M, Gor W, Liu F, Truong C, Whaley R, Woon M, Zhou T, Altman RB, Klein TE.

Nucleic Acids Res. 2008 Jan;36(Database issue):D913-8. Epub 2007 Nov 21.

42.

The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes.

Hanashima C, Fernandes M, Hebert JM, Fishell G.

J Neurosci. 2007 Oct 10;27(41):11103-11.

43.

Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly.

Fernandes M, Gutin G, Alcorn H, McConnell SK, Hébert JM.

Development. 2007 Nov;134(21):3789-94. Epub 2007 Oct 3.

44.

FGF signalling generates ventral telencephalic cells independently of SHH.

Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hébert JM.

Development. 2006 Aug;133(15):2937-46. Epub 2006 Jul 3.

45.

Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers.

Storm EE, Garel S, Borello U, Hebert JM, Martinez S, McConnell SK, Martin GR, Rubenstein JL.

Development. 2006 May;133(9):1831-44.

46.

Inactivation of Tbx1 in the pharyngeal endoderm results in 22q11DS malformations.

Arnold JS, Werling U, Braunstein EM, Liao J, Nowotschin S, Edelmann W, Hebert JM, Morrow BE.

Development. 2006 Mar;133(5):977-87. Epub 2006 Feb 1.

47.

Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum.

Tole S, Gutin G, Bhatnagar L, Remedios R, Hébert JM.

Dev Biol. 2006 Jan 1;289(1):141-51. Epub 2005 Nov 23.

48.

Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse.

Kawauchi S, Shou J, Santos R, Hébert JM, McConnell SK, Mason I, Calof AL.

Development. 2005 Dec;132(23):5211-23. Epub 2005 Nov 2.

49.

Unraveling the molecular pathways that regulate early telencephalon development.

Hébert JM.

Curr Top Dev Biol. 2005;69:17-37. Review.

PMID:
16243595
50.

Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap.

Sansom SN, Hébert JM, Thammongkol U, Smith J, Nisbet G, Surani MA, McConnell SK, Livesey FJ.

Development. 2005 Sep;132(17):3947-61. Epub 2005 Aug 3.

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