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Items: 40

1.

C-I and C-F bond-breaking dynamics in the dissociative electron ionization of CF3I.

Köckert H, Heathcote D, Lee JWL, Zhou W, Richardson V, Vallance C.

Phys Chem Chem Phys. 2019 Jul 3;21(26):14296-14305. doi: 10.1039/c8cp06682e.

PMID:
30643915
2.

Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent.

Foote KM, Nissink JWM, McGuire T, Turner P, Guichard S, Yates JWT, Lau A, Blades K, Heathcote D, Odedra R, Wilkinson G, Wilson Z, Wood CM, Jewsbury PJ.

J Med Chem. 2018 Nov 21;61(22):9889-9907. doi: 10.1021/acs.jmedchem.8b01187. Epub 2018 Nov 10.

PMID:
30346772
3.

Guidelines for Risk-Based Changeover of Biopharma Multi-Product Facilities.

Lynch R, Barabani D, Bellorado K, Canisius P, Heathcote D, Johnson A, Wyman N, Parry DW.

PDA J Pharm Sci Technol. 2018 Jan-Feb;72(1):91-103. doi: 10.5731/pdajpst.2016.007419. Epub 2017 Oct 12.

PMID:
29030526
4.

Photofragmentation dynamics of N,N-dimethylformamide following excitation at 193 nm.

Lipciuc ML, Gardiner SH, Karsili TNV, Lee JWL, Heathcote D, Ashfold MNR, Vallance C.

J Chem Phys. 2017 Jul 7;147(1):013941. doi: 10.1063/1.4983704.

5.

Evaluation of rodent spaceflight in the NASA animal enclosure module for an extended operational period (up to 35 days).

Moyer EL, Dumars PM, Sun GS, Martin KJ, Heathcote DG, Boyle RD, Skidmore MG.

NPJ Microgravity. 2016 Mar 3;2:16002. doi: 10.1038/npjmgrav.2016.2. eCollection 2016.

6.

T cell metabolism. The protein LEM promotes CD8⁺ T cell immunity through effects on mitochondrial respiration.

Okoye I, Wang L, Pallmer K, Richter K, Ichimura T, Haas R, Crouse J, Choi O, Heathcote D, Lovo E, Mauro C, Abdi R, Oxenius A, Rutschmann S, Ashton-Rickardt PG.

Science. 2015 May 29;348(6238):995-1001. doi: 10.1126/science.aaa7516. Epub 2015 Apr 16. Erratum in: Science. 2015 Oct 23;350(6259):aad6462. Retraction in: Science. 2016 Dec 16;354(6318):1385.

7.

Approaches to design non-covalent inhibitors for human granzyme B (hGrB).

Kim MS, Buisson LA, Heathcote DA, Hu H, Braddock DC, Barrett AG, Ashton-Rickardt PG, Snyder JP.

Org Biomol Chem. 2014 Nov 28;12(44):8952-65. doi: 10.1039/c4ob01874e.

PMID:
25277547
8.

A meta-analysis of prevalence rates and moderating factors for cancer-related post-traumatic stress disorder.

Abbey G, Thompson SB, Hickish T, Heathcote D.

Psychooncology. 2015 Apr;24(4):371-81. doi: 10.1002/pon.3654. Epub 2014 Aug 22.

9.

Development of a cyclin-dependent kinase inhibitor devoid of ABC transporter-dependent drug resistance.

Kaliszczak M, Patel H, Kroll SH, Carroll L, Smith G, Delaney S, Heathcote DA, Bondke A, Fuchter MJ, Coombes RC, Barrett AG, Ali S, Aboagye EO.

Br J Cancer. 2013 Oct 29;109(9):2356-67. doi: 10.1038/bjc.2013.584. Epub 2013 Sep 26.

10.

Serine protease inhibitor 6 plays a critical role in protecting murine granzyme B-producing regulatory T cells.

Azzi J, Skartsis N, Mounayar M, Magee CN, Batal I, Ting C, Moore R, Riella LV, Ohori S, Abdoli R, Smith B, Fiorina P, Heathcote D, Bakhos T, Ashton-Rickardt PG, Abdi R.

J Immunol. 2013 Sep 1;191(5):2319-27. doi: 10.4049/jimmunol.1300851. Epub 2013 Aug 2.

11.

A deficiency in nucleoside salvage impairs murine lymphocyte development, homeostasis, and survival.

Choi O, Heathcote DA, Ho KK, Müller PJ, Ghani H, Lam EW, Ashton-Rickardt PG, Rutschmann S.

J Immunol. 2012 Apr 15;188(8):3920-7. doi: 10.4049/jimmunol.1102587. Epub 2012 Mar 9.

12.

The novel role of SERPINB9 in cytotoxic protection of human mesenchymal stem cells.

El Haddad N, Moore R, Heathcote D, Mounayar M, Azzi J, Mfarrej B, Batal I, Ting C, Atkinson M, Sayegh MH, Ashton-Rickardt PG, Abdi R.

J Immunol. 2011 Sep 1;187(5):2252-60. doi: 10.4049/jimmunol.1003981. Epub 2011 Jul 27.

13.

A simple laboratory practical to illustrate RNA mediated gene interference using drosophila cell culture.

Buluwela L, Kamalati T, Photiou A, Heathcote DA, Jones MD, Ali S.

Biochem Mol Biol Educ. 2010 Nov;38(6):393-9. doi: 10.1002/bmb.20437.

14.

Benefits of mTOR kinase targeting in oncology: pre-clinical evidence with AZD8055.

Marshall G, Howard Z, Dry J, Fenton S, Heathcote D, Gray N, Keen H, Logie A, Holt S, Smith P, Guichard SM.

Biochem Soc Trans. 2011 Apr;39(2):456-9. doi: 10.1042/BST0390456. Review.

PMID:
21428919
15.

Sixty years of antibodies to MNS system hybrid glycophorins: what have we learned?

Heathcote DJ, Carroll TE, Flower RL.

Transfus Med Rev. 2011 Apr;25(2):111-24. doi: 10.1016/j.tmrv.2010.11.003. Epub 2011 Feb 23. Review.

PMID:
21345645
16.

Assessment of biomarkers of drug-induced kidney injury in cynomolgus monkeys treated with a triple reuptake inhibitor.

Guha M, Heier A, Price S, Bielenstein M, Caccese RG, Heathcote DI, Simpson TR, Stong DB, Bodes E.

Toxicol Sci. 2011 Apr;120(2):269-83. doi: 10.1093/toxsci/kfr013. Epub 2011 Jan 22.

PMID:
21258088
17.

A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration.

Heathcote DA, Patel H, Kroll SH, Hazel P, Periyasamy M, Alikian M, Kanneganti SK, Jogalekar AS, Scheiper B, Barbazanges M, Blum A, Brackow J, Siwicka A, Pace RD, Fuchter MJ, Snyder JP, Liotta DC, Freemont PS, Aboagye EO, Coombes RC, Barrett AG, Ali S.

J Med Chem. 2010 Dec 23;53(24):8508-22. doi: 10.1021/jm100732t. Epub 2010 Nov 16.

PMID:
21080703
18.

Mesenchymal stem cells express serine protease inhibitor to evade the host immune response.

El Haddad N, Heathcote D, Moore R, Yang S, Azzi J, Mfarrej B, Atkinson M, Sayegh MH, Lee JS, Ashton-Rickardt PG, Abdi R.

Blood. 2011 Jan 27;117(4):1176-83. doi: 10.1182/blood-2010-06-287979. Epub 2010 Nov 12.

19.

Evaluation of a convenient method of assessing rodent visual function in safety pharmacology studies: effects of sodium iodate on visual acuity and retinal morphology in albino and pigmented rats and mice.

Redfern WS, Storey S, Tse K, Hussain Q, Maung KP, Valentin JP, Ahmed G, Bigley A, Heathcote D, McKay JS.

J Pharmacol Toxicol Methods. 2011 Jan-Feb;63(1):102-14. doi: 10.1016/j.vascn.2010.06.008. Epub 2010 Jul 7.

PMID:
20619348
20.

Novel antibody screening cells, MUT+Mur kodecytes, created by attaching peptides onto red blood cells.

Heathcote D, Carroll T, Wang JJ, Flower R, Rodionov I, Tuzikov A, Bovin N, Henry S.

Transfusion. 2010 Mar;50(3):635-41. doi: 10.1111/j.1537-2995.2009.02480.x. Epub 2009 Nov 11.

PMID:
19912581
21.

The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity.

Ali S, Heathcote DA, Kroll SH, Jogalekar AS, Scheiper B, Patel H, Brackow J, Siwicka A, Fuchter MJ, Periyasamy M, Tolhurst RS, Kanneganti SK, Snyder JP, Liotta DC, Aboagye EO, Barrett AG, Coombes RC.

Cancer Res. 2009 Aug 1;69(15):6208-15. doi: 10.1158/0008-5472.CAN-09-0301. Epub 2009 Jul 28.

22.

Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-alpha and the transcriptional repressor PLZF.

Buluwela L, Pike J, Mazhar D, Kamalati T, Hart SM, Al-Jehani R, Yahaya H, Patel N, Sarwar N, Heathcote DA, Schwickerath O, Phoenix F, Hill R, Aboagye E, Shousha S, Waxman J, Lemoine NR, Zelent A, Coombes RC, Ali S.

Gene Ther. 2005 Mar;12(5):452-60. Erratum in: Gene Ther. 2005 Mar;12(6):552. Sarwarl, N [corrected to Sarwar, N]. Gene Ther. 2005 May;12(10):862.

PMID:
15647773
23.

The harmonization of cardiac troponin I measurement is independent of sample time collection but is dependent on the source of calibrator.

Tate JR, Heathcote D, Koerbin G, Thean G, Andriske D, Bonar J, Gill J.

Clin Chim Acta. 2002 Oct;324(1-2):13-23.

PMID:
12204420
24.

Tricyclic drugs for depression in children and adolescents.

Hazell P, O'Connell D, Heathcote D, Henry D.

Cochrane Database Syst Rev. 2002;(2):CD002317. Review. Update in: Cochrane Database Syst Rev. 2013;6:CD002317.

PMID:
12076448
25.

Tricyclic drugs for depression in children and adolescents.

Hazell P, O'Connell D, Heathcote D, Henry D.

Cochrane Database Syst Rev. 2000;(3):CD002317. Review. Update in: Cochrane Database Syst Rev. 2002;(2):CD002317.

PMID:
10908557
26.

Midwives in action.

Heathcote D.

Aust Nurs J. 1998 Jun;5(11):35. No abstract available.

PMID:
10639964
27.

The lack of standardization of cardiac troponin I assay systems.

Tate JR, Heathcote D, Rayfield J, Hickman PE.

Clin Chim Acta. 1999 Jun 30;284(2):141-9.

PMID:
10451241
28.

Effortful and automatic information processing in boys with ADHD and specific learning disorders.

Hazell PL, Carr VJ, Lewin TJ, Dewis SA, Heathcote DM, Brucki BM.

J Child Psychol Psychiatry. 1999 Feb;40(2):275-86.

PMID:
10188710
29.

Gravitropic responses of the Avena coleoptile in space and on clinostats. II. Is reciprocity valid?

Johnsson A, Brown AH, Chapman DK, Heathcote D, Karlsson C.

Physiol Plant. 1995 Sep;95(1):34-8.

PMID:
11539923
30.

Gravitropic responses of the Avena coleoptile in space and on clinostats. I. Gravitropic response thresholds.

Brown AH, Chapman DK, Johnsson A, Heathcote D.

Physiol Plant. 1995 Sep;95(1):27-33.

PMID:
11539922
31.

Nastic curvatures of wheat coleoptiles that develop in true microgravity.

Heathcote DG, Chapman DK, Brown AH.

Plant Cell Environ. 1995 Jul;18(7):818-22.

PMID:
11539343
32.

Efficacy of tricyclic drugs in treating child and adolescent depression: a meta-analysis.

Hazell P, O'Connell D, Heathcote D, Robertson J, Henry D.

BMJ. 1995 Apr 8;310(6984):897-901.

33.

Patterns of Staphylococcus aureus colonization, toxin production, immunity and illness in burned children.

Childs C, Edwards-Jones V, Heathcote DM, Dawson M, Davenport PJ.

Burns. 1994 Dec;20(6):514-21.

PMID:
7880416
34.

The Gravitational Plant Physiology Facility--description of equipment developed for biological research in Spacelab.

Heathcote DG, Chapman DK, Brown AH, Lewis RF.

Microgravity Sci Technol. 1994 Sep;7(3):270-5.

PMID:
11541487
35.

Determination of temafloxacin, sarafloxacin, and difloxacin in bulk drug and dosage forms by high-performance liquid chromatography.

Bauer JF, Elrod L Jr, Fornnarino JR, Heathcote DE, Krogh SK, Linton CL, Norris BJ, Quick JE.

Pharm Res. 1990 Nov;7(11):1177-80.

PMID:
2293219
36.
37.
39.

High-performance liquid chromatographic, stability indicating assay for disodium EDTA in ophthalmic preparations.

Bauer J, Heathcote D, Krogh S.

J Chromatogr. 1986 Nov 21;369(2):422-5. No abstract available.

PMID:
3100572
40.

The search for "menotoxin".

Bryant JA, Heathcote DG, Pickles VR.

Lancet. 1977 Apr 2;1(8014):753. No abstract available.

PMID:
66546

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