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Items: 1 to 50 of 117

1.

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection.

Buckley CM, Heath VL, Guého A, Bosmani C, Knobloch P, Sikakana P, Personnic N, Dove SK, Michell RH, Meier R, Hilbi H, Soldati T, Insall RH, King JS.

PLoS Pathog. 2019 Feb 7;15(2):e1007551. doi: 10.1371/journal.ppat.1007551. eCollection 2019 Feb.

2.

Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells.

Noy PJ, Gavin RL, Colombo D, Haining EJ, Reyat JS, Payne H, Thielmann I, Lokman AB, Neag G, Yang J, Lloyd T, Harrison N, Heath VL, Gardiner C, Whitworth KM, Robinson J, Koo CZ, Di Maio A, Harrison P, Lee SP, Michelangeli F, Kalia N, Rainger GE, Nieswandt B, Brill A, Watson SP, Tomlinson MG.

Haematologica. 2018 Dec 20. pii: haematol.2018.194241. doi: 10.3324/haematol.2018.194241. [Epub ahead of print]

3.

RCAN1.4 regulates VEGFR-2 internalisation, cell polarity and migration in human microvascular endothelial cells.

Alghanem AF, Wilkinson EL, Emmett MS, Aljasir MA, Holmes K, Rothermel BA, Simms VA, Heath VL, Cross MJ.

Angiogenesis. 2017 Aug;20(3):341-358. doi: 10.1007/s10456-017-9542-0. Epub 2017 Mar 7.

4.

Sunitinib Treatment Enhances Metastasis of Innately Drug-Resistant Breast Tumors.

Wragg JW, Heath VL, Bicknell R.

Cancer Res. 2017 Feb 15;77(4):1008-1020. doi: 10.1158/0008-5472.CAN-16-1982. Epub 2016 Dec 23.

5.

Tube-Forming Assays.

Brown RM, Meah CJ, Heath VL, Styles IB, Bicknell R.

Methods Mol Biol. 2016;1430:149-57. doi: 10.1007/978-1-4939-3628-1_9.

PMID:
27172951
6.

Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer.

Ferguson HJ, Wragg JW, Ward S, Heath VL, Ismail T, Bicknell R.

Oncotarget. 2016 Apr 12;7(15):20440-54. doi: 10.18632/oncotarget.7812.

7.

MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome.

Wragg JW, Finnity JP, Anderson JA, Ferguson HJ, Porfiri E, Bhatt RI, Murray PG, Heath VL, Bicknell R.

Cancer Res. 2016 Apr 15;76(8):2314-26. doi: 10.1158/0008-5472.CAN-15-1364. Epub 2016 Feb 26.

8.

Robo4 vaccines induce antibodies that retard tumor growth.

Zhuang X, Ahmed F, Zhang Y, Ferguson HJ, Steele JC, Steven NM, Nagy Z, Heath VL, Toellner KM, Bicknell R.

Angiogenesis. 2015 Jan;18(1):83-95. doi: 10.1007/s10456-014-9448-z. Epub 2014 Oct 28.

PMID:
25348086
9.

RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly.

Wilson E, Leszczynska K, Poulter NS, Edelmann F, Salisbury VA, Noy PJ, Bacon A, Rappoport JZ, Heath JK, Bicknell R, Heath VL.

J Cell Sci. 2014 Jul 15;127(Pt 14):3039-51. doi: 10.1242/jcs.140434. Epub 2014 Jun 13.

10.

Establishment of a healthy human range for the whole blood "OX40" assay for the detection of antigen-specific CD4+ T cells by flow cytometry.

Sadler R, Bateman EA, Heath V, Patel SY, Schwingshackl PP, Cullinane AC, Ayers L, Ferry BL.

Cytometry B Clin Cytom. 2014 Sep;86(5):350-61. doi: 10.1002/cyto.b.21165. Epub 2014 May 14.

11.

Obesity: Genes and a hearty appetite conspire to increase childhood obesity risk.

Heath V.

Nat Rev Endocrinol. 2014 Apr;10(4):187. doi: 10.1038/nrendo.2014.24. Epub 2014 Mar 4. No abstract available.

PMID:
24590186
12.

Establishment of a healthy human range for the whole blood 'OX40' assay for the detection of antigen-specific CD4+ T cells by flow cytometry.

Sadler R, Bateman EA, Heath V, Patel SY, Schwingshackl PP, Cullinane AC, Ayers L, Ferry BL.

Cytometry B Clin Cytom. 2014 Feb 11. doi: 10.1002/cytob.21165. [Epub ahead of print]

13.

Metabolism: Altered neuronal circuits control metabolic fate.

Heath V.

Nat Rev Endocrinol. 2014 Apr;10(4):190. doi: 10.1038/nrendo.2014.14. Epub 2014 Feb 11. No abstract available.

PMID:
24514262
14.

Bone: Diagnostic blood test for osteoporosis moves a step closer.

Heath V.

Nat Rev Endocrinol. 2014 Apr;10(4):189. doi: 10.1038/nrendo.2014.10. Epub 2014 Feb 4. No abstract available.

PMID:
24492181
15.

Metabolism: Feel the burn--muscle metabolite couples exercise to heat production.

Heath V.

Nat Rev Endocrinol. 2014 Apr;10(4):188. doi: 10.1038/nrendo.2014.4. Epub 2014 Jan 28. No abstract available.

PMID:
24468648
16.

Osteoporosis: Novel antibody therapy shows potential for building bone.

Heath V.

Nat Rev Rheumatol. 2014 Mar;10(3):126. doi: 10.1038/nrrheum.2014.3. Epub 2014 Jan 21. No abstract available.

PMID:
24445862
17.

Pharmacotherapy: Novel antibody therapy demonstrates potential for building bone in osteoporosis.

Heath V.

Nat Rev Endocrinol. 2014 Mar;10(3):125. doi: 10.1038/nrendo.2014.1. Epub 2014 Jan 21. No abstract available.

PMID:
24445586
18.

Pharmacotherapy: a new option for Cushing disease?

Heath V.

Nat Rev Endocrinol. 2014 Mar;10(3):127. doi: 10.1038/nrendo.2013.266. Epub 2014 Jan 7. No abstract available.

PMID:
24393783
19.

Development: Scope of DSD-linked conditions shown.

Heath V.

Nat Rev Endocrinol. 2014 Mar;10(3):127. doi: 10.1038/nrendo.2013.260. Epub 2013 Dec 24. No abstract available.

PMID:
24366118
20.

Lipids: Cholesterol metabolite unmasked as a key player in breast cancer.

Heath V.

Nat Rev Endocrinol. 2014 Feb;10(2):65. doi: 10.1038/nrendo.2013.254. Epub 2013 Dec 17. No abstract available.

PMID:
24342886
21.

The NMC's adaptation framework for European nurses.

Glasper A, Heath V, James J, Porch J, Trotter A.

Br J Nurs. 2012 Jan 26-Feb 8;21(2):124-5. No abstract available.

PMID:
22306643
22.

A systematic review of placement-related attrition in nurse education.

Eick SA, Williamson GR, Heath V.

Int J Nurs Stud. 2012 Oct;49(10):1299-309. doi: 10.1016/j.ijnurstu.2011.12.004. Epub 2012 Jan 23. Review.

PMID:
22269138
23.

The emerging role of tetraspanin microdomains on endothelial cells.

Bailey RL, Herbert JM, Khan K, Heath VL, Bicknell R, Tomlinson MG.

Biochem Soc Trans. 2011 Dec;39(6):1667-73. doi: 10.1042/BST20110745. Review.

PMID:
22103505
24.

The role of RhoJ in endothelial cell biology and angiogenesis.

Leszczynska K, Kaur S, Wilson E, Bicknell R, Heath VL.

Biochem Soc Trans. 2011 Dec;39(6):1606-11. doi: 10.1042/BST20110702. Review.

PMID:
22103495
25.

Shear stress, tip cells and regulators of endothelial migration.

Zhuang X, Cross D, Heath VL, Bicknell R.

Biochem Soc Trans. 2011 Dec;39(6):1571-5. doi: 10.1042/BST20110746. Review.

PMID:
22103489
26.

Longitudinal evaluation of the impact of placement development teams on student support in clinical practice.

Williamson GR, Callaghan L, Whittlesea E, Mutton L, Heath V.

Open Nurs J. 2011;5:14-23. doi: 10.2174/1874434601105010014. Epub 2011 Feb 24.

27.

Placement Development Teams and interprofessional education with healthcare students.

Williamson GR, Callaghan L, Whittlesea E, Mutton L, Heath V.

J Clin Nurs. 2011 Aug;20(15-16):2305-14. doi: 10.1111/j.1365-2702.2010.03637.x. Epub 2011 Apr 25.

PMID:
21518056
28.

Genetics: New data on Hajdu-Cheney syndrome turns up bone research a NOTCH.

Heath V.

Nat Rev Endocrinol. 2011 Jun;7(6):311. doi: 10.1038/nrendo.2011.60. Epub 2011 Apr 19. No abstract available.

PMID:
21502983
29.

Reproductive endocrinology: CatSper solves mystery of progesterone action on sperm.

Heath V.

Nat Rev Endocrinol. 2011 Jun;7(6):316. doi: 10.1038/nrendo.2011.71. Epub 2011 Apr 19. No abstract available.

PMID:
21502978
30.

Pituitary tumors: predicting glucose metabolism after surgery for acromegaly.

Heath V.

Nat Rev Endocrinol. 2011 May;7(5):250. doi: 10.1038/nrendo.2011.50. Epub 2011 Mar 22. No abstract available.

PMID:
21451480
31.

Does insulin resistance influence breast cancer outcomes?

Heath V.

Nat Rev Endocrinol. 2011 Mar;7(3):123. No abstract available.

PMID:
21449122
32.

Bone: Teriparatide improves outcomes of periodontal surgery.

Heath V.

Nat Rev Endocrinol. 2011 Jan;7(1):4. doi: 10.1038/nrendo.2010.208. No abstract available.

PMID:
21197707
33.

Obesity: Benefits of intensive lifestyle modification programs in the spotlight.

Heath V.

Nat Rev Endocrinol. 2011 Jan;7(1):1. doi: 10.1038/nrendo.2010.201. No abstract available.

PMID:
21197700
34.

RhoJ/TCL regulates endothelial motility and tube formation and modulates actomyosin contractility and focal adhesion numbers.

Kaur S, Leszczynska K, Abraham S, Scarcia M, Hiltbrunner S, Marshall CJ, Mavria G, Bicknell R, Heath VL.

Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):657-64. doi: 10.1161/ATVBAHA.110.216341. Epub 2010 Dec 9.

PMID:
21148427
35.

Bone: Promising combination therapy for children with osteogenesis imperfecta.

Heath V.

Nat Rev Endocrinol. 2010 Oct;6(10):535. doi: 10.1038/nrendo.2010.141. No abstract available.

PMID:
21080546
36.

Surgery: Laparoscopic sleeve gastrectomy as the first-line surgical option for morbid obesity.

Heath V.

Nat Rev Endocrinol. 2010 Oct;6(10):534. doi: 10.1038/nrendo.2010.139. No abstract available.

PMID:
21080542
37.

Improving student support using Placement Development Teams: staff and student perceptions.

Williamson GR, Callaghan L, Whittlesea E, Heath V.

J Clin Nurs. 2011 Mar;20(5-6):828-36. doi: 10.1111/j.1365-2702.2010.03287.x. Epub 2010 Oct 6.

PMID:
21040030
38.

Thyroid function: Sorafenib alters metabolism of T3.

Heath V.

Nat Rev Endocrinol. 2010 Sep;6(9):473. doi: 10.1038/nrendo.2010.111. No abstract available.

PMID:
20803800
39.

Nutrition: Giving vitamin A supplements to mothers has lasting benefits for their offspring.

Heath V.

Nat Rev Endocrinol. 2010 Sep;6(9):472. doi: 10.1038/nrendo.2010.109. No abstract available.

PMID:
20803798
40.

Differentiation: from alpha to beta.

Heath V.

Nat Rev Endocrinol. 2010 Aug;6(8):417. doi: 10.1038/nrendo.2010.100. No abstract available.

PMID:
20681070
41.

Reproductive endocrinology: High-dose cabergoline improves pregnancy rates in women with prolactinomas.

Heath V.

Nat Rev Endocrinol. 2010 Aug;6(8):415. doi: 10.1038/nrendo.2010.95. No abstract available.

PMID:
20681039
42.

Game over for sports cheats?

Heath V.

Nat Rev Endocrinol. 2010 Aug;6(8):413. doi: 10.1038/nrendo.2010.120. No abstract available.

PMID:
20657542
43.

Cancer: Second-line therapy for adrenocortical carcinoma proves beneficial.

Heath V.

Nat Rev Endocrinol. 2010 Jul;6(7):355. doi: 10.1038/nrendo.2010.76. No abstract available.

PMID:
20583342
44.

Diabetes: Progression of diabetic retinopathy found to be a potential risk during pregnancy.

Heath V.

Nat Rev Endocrinol. 2010 Jul;6(7):354. doi: 10.1038/nrendo.2010.73. No abstract available.

PMID:
20583339
45.

The perils of plastic.

Heath V.

Nat Rev Endocrinol. 2010 May;6(5):237. doi: 10.1038/nrendo.2010.48. No abstract available.

PMID:
20414313
46.

A crossroads for diabetes care?

Heath V.

Nat Rev Endocrinol. 2010 Mar;6(3):117. doi: 10.1038/nrendo.2010.5. No abstract available.

PMID:
20173769
47.

Functionally defining the endothelial transcriptome, from Robo4 to ECSCR.

Verissimo AR, Herbert JM, Heath VL, Legg JA, Sheldon H, Andre M, Swain RK, Bicknell R.

Biochem Soc Trans. 2009 Dec;37(Pt 6):1214-7. doi: 10.1042/BST0371214.

PMID:
19909249
48.

TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival.

Huser CA, Pringle MA, Heath VJ, Bell AK, Kendrick H, Smalley MJ, Crighton D, Ryan KM, Gusterson BA, Stein T.

Cell Death Differ. 2010 Feb;17(2):304-15. doi: 10.1038/cdd.2009.126. Epub 2009 Sep 11.

49.

Anticancer strategies involving the vasculature.

Heath VL, Bicknell R.

Nat Rev Clin Oncol. 2009 Jul;6(7):395-404. doi: 10.1038/nrclinonc.2009.52. Epub 2009 May 7. Review.

PMID:
19424102
50.

Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors.

Sheldon H, Andre M, Legg JA, Heal P, Herbert JM, Sainson R, Sharma AS, Kitajewski JK, Heath VL, Bicknell R.

FASEB J. 2009 Feb;23(2):513-22. doi: 10.1096/fj.07-098269. Epub 2008 Oct 23.

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