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Durable multitransgene expression in vivo using systemic, nonviral DNA delivery.

Handumrongkul C, Ye AL, Chmura SA, Soroceanu L, Mack M, Ice RJ, Thistle R, Myers M, Ursu SJ, Liu Y, Kashani-Sabet M, Heath TD, Liggitt D, Lewis DB, Debs R.

Sci Adv. 2019 Nov 27;5(11):eaax0217. doi: 10.1126/sciadv.aax0217. eCollection 2019 Nov.


Quality of reporting in abstracts of RCTs published in emergency medicine journals: a systematic survey of the literature suggests we can do better.

Germini F, Marcucci M, Fedele M, Galli MG, Heath T, Mbuagbaw L, Salvatori V, Veronese G, Worster A, Thabane L.

Emerg Med J. 2019 Nov 6. pii: emermed-2019-208629. doi: 10.1136/emermed-2019-208629. [Epub ahead of print]


Inferring processes of coevolutionary diversification in a community of Panamanian strangler figs and associated pollinating wasps.

Satler JD, Herre EA, Jandér KC, Eaton DAR, Machado CA, Heath TA, Nason JD.

Evolution. 2019 Nov;73(11):2295-2311. doi: 10.1111/evo.13809. Epub 2019 Aug 8.


A Respiratory Therapist-Driven Asthma Pathway Reduced Hospital Length of Stay in the Pediatric Intensive Care Unit.

Miller AG, Haynes KE, Gates RM, Zimmerman KO, Heath TS, Bartlett KW, McLean HS, Rehder KJ.

Respir Care. 2019 Nov;64(11):1325-1332. doi: 10.4187/respcare.06626. Epub 2019 May 14.


Veterinary education: how we got to where we are.

Heath T.

Aust Vet J. 2018 Jun;96(6):216-222. doi: 10.1111/avj.12702. Epub 2018 May 2. No abstract available.


Effects of Methadone on Corrected Q-T Interval Prolongation in Critically Ill Children.

Heath TS, Greenberg RG, Hupp SR, Turner DA, Hornik CP, Zimmerman KO.

J Pediatr Pharmacol Ther. 2018 Mar-Apr;23(2):119-124. doi: 10.5863/1551-6776-23.2.119.


Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target.

Heath TK, Lutz MR Jr, Reidl CT, Guzman ER, Herbert CA, Nocek BP, Holz RC, Olsen KW, Ballicora MA, Becker DP.

PLoS One. 2018 Apr 26;13(4):e0196010. doi: 10.1371/journal.pone.0196010. eCollection 2018.


The fossilized birth-death model for the analysis of stratigraphic range data under different speciation modes.

Stadler T, Gavryushkina A, Warnock RCM, Drummond AJ, Heath TA.

J Theor Biol. 2018 Jun 14;447:41-55. doi: 10.1016/j.jtbi.2018.03.005. Epub 2018 Mar 14.


Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.

Nocek B, Reidl C, Starus A, Heath T, Bienvenue D, Osipiuk J, Jedrzejczak R, Joachimiak A, Becker DP, Holz RC.

Biochemistry. 2018 Feb 6;57(5):574-584. doi: 10.1021/acs.biochem.7b01151. Epub 2018 Jan 12.


The utility of ultrasound in showing a unique cause of posterior interosseous nerve syndrome.

Soh D, Cappelen-Smith C, Korber J, Heath T, Cordato D.

eNeurologicalSci. 2017 Jul 20;8:34-35. doi: 10.1016/j.ensci.2017.07.002. eCollection 2017 Sep. No abstract available.


Taming the BEAST-A Community Teaching Material Resource for BEAST 2.

Barido-Sottani J, Bošková V, Plessis LD, Kühnert D, Magnus C, Mitov V, Müller NF, PecErska J, Rasmussen DA, Zhang C, Drummond AJ, Heath TA, Pybus OG, Vaughan TG, Stadler T.

Syst Biol. 2018 Jan 1;67(1):170-174. doi: 10.1093/sysbio/syx060.


Association Between Deep Sedation from Continuous Intravenous Sedatives and Extubation Failures in Mechanically Ventilated Patients in the Pediatric Intensive Care Unit.

Schultheis JM, Heath TS, Turner DA.

J Pediatr Pharmacol Ther. 2017 Mar-Apr;22(2):106-111. doi: 10.5863/1551-6776-22.2.106.


Phylogenetic Inference Using RevBayes.

Höhna S, Landis MJ, Heath TA.

Curr Protoc Bioinformatics. 2017 May 2;57:6.16.1-6.16.34. doi: 10.1002/cpbi.22.


Clinical Pharmacology and Translational Aspects of Bispecific Antibodies.

Trivedi A, Stienen S, Zhu M, Li H, Yuraszeck T, Gibbs J, Heath T, Loberg R, Kasichayanula S.

Clin Transl Sci. 2017 May;10(3):147-162. doi: 10.1111/cts.12459. Epub 2017 Mar 15. Review. No abstract available.


Bayesian Total-Evidence Dating Reveals the Recent Crown Radiation of Penguins.

Gavryushkina A, Heath TA, Ksepka DT, Stadler T, Welch D, Drummond AJ.

Syst Biol. 2017 Jan 1;66(1):57-73. doi: 10.1093/sysbio/syw060.


Pharmacokinetics and Dosing of Anti-infective Drugs in Patients on Extracorporeal Membrane Oxygenation: A Review of the Current Literature.

Sherwin J, Heath T, Watt K.

Clin Ther. 2016 Sep;38(9):1976-94. doi: 10.1016/j.clinthera.2016.07.169. Epub 2016 Aug 21. Review.


RevBayes: Bayesian Phylogenetic Inference Using Graphical Models and an Interactive Model-Specification Language.

Höhna S, Landis MJ, Heath TA, Boussau B, Lartillot N, Moore BR, Huelsenbeck JP, Ronquist F.

Syst Biol. 2016 Jul;65(4):726-36. doi: 10.1093/sysbio/syw021. Epub 2016 May 28.


Indirect assessment of neutralizing anti-drug antibodies utilizing pharmacokinetic assay data.

Vettermann C, Ortiz J, Lee S, Sanchez S, Victor HP, Ma M, Heath T, Gupta S.

J Immunol Methods. 2016 Feb;429:28-38. doi: 10.1016/j.jim.2015.12.010. Epub 2015 Dec 19.


Postoperative Analgesia Provided by Liposomal Hydromorphone in Client-Owned Dogs Undergoing Limb Amputation.

Krugner-Higby L, Smith LJ, Schmidt B, Steagall PV, Brown C, Heath TD.

J Am Anim Hosp Assoc. 2016 Jan-Feb;52(1):13-21. doi: 10.5326/JAAHA-MS-6113. Epub 2015 Nov 25.


Total-Evidence Dating under the Fossilized Birth-Death Process.

Zhang C, Stadler T, Klopfstein S, Heath TA, Ronquist F.

Syst Biol. 2016 Mar;65(2):228-49. doi: 10.1093/sysbio/syv080. Epub 2015 Oct 22.


Correction to: ''A Novel Loading Method for Doxycycline Liposomes for Intracellular Drug Delivery: Characterization of In Vitro and In Vivo Release Kinetics and Efficacy in a J774A.1 Cell Line Model of Mycobacterium smegmatis Infection".

Franklin RK, Marcus SA, Talaat AM, KuKanich BK, Sullivan R, Krugner-Higby LA, Heath TD.

Drug Metab Dispos. 2015 Nov;43(11):1805. doi: 10.1124/dmd.115.063602err. No abstract available.


Madness at the movies: prioritised movies for self-directed learning by medical students.

Wilson N, Heath D, Heath T, Gallagher P, Huthwaite M.

Australas Psychiatry. 2014 Oct;22(5):450-3. doi: 10.1177/1039856214545550. Epub 2014 Aug 17.


The fossilized birth-death process for coherent calibration of divergence-time estimates.

Heath TA, Huelsenbeck JP, Stadler T.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E2957-66. doi: 10.1073/pnas.1319091111. Epub 2014 Jul 9.


Probabilistic graphical model representation in phylogenetics.

Höhna S, Heath TA, Boussau B, Landis MJ, Ronquist F, Huelsenbeck JP.

Syst Biol. 2014 Sep;63(5):753-71. doi: 10.1093/sysbio/syu039. Epub 2014 Jun 20.


Phylotastic! Making tree-of-life knowledge accessible, reusable and convenient.

Stoltzfus A, Lapp H, Matasci N, Deus H, Sidlauskas B, Zmasek CM, Vaidya G, Pontelli E, Cranston K, Vos R, Webb CO, Harmon LJ, Pirrung M, O'Meara B, Pennell MW, Mirarab S, Rosenberg MS, Balhoff JP, Bik HM, Heath TA, Midford PE, Brown JW, McTavish EJ, Sukumaran J, Westneat M, Alfaro ME, Steele A, Jordan G.

BMC Bioinformatics. 2013 May 13;14:158. doi: 10.1186/1471-2105-14-158.


Pharmacokinetics of ammonium sulfate gradient loaded liposome-encapsulated oxymorphone and hydromorphone in healthy dogs.

Smith LJ, Kukanich BK, Krugner-Higby LA, Schmidt BH, Heath TD.

Vet Anaesth Analg. 2013 Sep;40(5):537-45. doi: 10.1111/vaa.12042. Epub 2013 Apr 20.


Antinociceptive effects of long-acting nalbuphine decanoate after intramuscular administration to Hispaniolan Amazon parrots (Amazona ventralis).

Sanchez-Migallon Guzman D, Braun JM, Steagall PV, Keuler NS, Heath TD, Krugner-Higby LA, Brown CS, Paul-Murphy JR.

Am J Vet Res. 2013 Feb;74(2):196-200. doi: 10.2460/ajvr.74.2.196.


Pharmacokinetics of long-acting nalbuphine decanoate after intramuscular administration to Hispaniolan Amazon parrots (Amazona ventralis).

Sanchez-Migallon Guzman D, KuKanich B, Heath TD, Krugner-Higby LA, Barker SA, Brown CS, Paul-Murphy JR.

Am J Vet Res. 2013 Feb;74(2):191-5. doi: 10.2460/ajvr.74.2.191.


Acute intoxication caused by a synthetic cannabinoid in two adolescents.

Heath TS, Burroughs Z, Thompson AJ, Tecklenburg FW.

J Pediatr Pharmacol Ther. 2012 Apr;17(2):177-81. doi: 10.5863/1551-6776-17.2.177.


Reference measurement procedures for Alzheimer's disease cerebrospinal fluid biomarkers: definitions and approaches with focus on amyloid β42.

Mattsson N, Zegers I, Andreasson U, Bjerke M, Blankenstein MA, Bowser R, Carrillo MC, Gobom J, Heath T, Jenkins R, Jeromin A, Kaplow J, Kidd D, Laterza OF, Lockhart A, Lunn MP, Martone RL, Mills K, Pannee J, Ratcliffe M, Shaw LM, Simon AJ, Soares H, Teunissen CE, Verbeek MM, Umek RM, Vanderstichele H, Zetterberg H, Blennow K, Portelius E.

Biomark Med. 2012 Aug;6(4):409-17. doi: 10.2217/bmm.12.39. Review.


Folinic acid administration after MTX GVHD prophylaxis in pediatric allo-SCT.

Hudspeth MP, Heath TS, Chiuzan C, Garrett-Mayer E, Nista E, Burton L, Ragucci D.

Bone Marrow Transplant. 2013 Jan;48(1):46-9. doi: 10.1038/bmt.2012.82. Epub 2012 May 21.


A hierarchical Bayesian model for calibrating estimates of species divergence times.

Heath TA.

Syst Biol. 2012 Oct;61(5):793-809. doi: 10.1093/sysbio/sys032. Epub 2012 Feb 14.


A review of oscillating water columns.

Heath TV.

Philos Trans A Math Phys Eng Sci. 2012 Jan 28;370(1959):235-45. doi: 10.1098/rsta.2011.0164.


A dirichlet process prior for estimating lineage-specific substitution rates.

Heath TA, Holder MT, Huelsenbeck JP.

Mol Biol Evol. 2012 Mar;29(3):939-55. doi: 10.1093/molbev/msr255. Epub 2011 Nov 2.


Epidural administration of liposome-encapsulated hydromorphone provides extended analgesia in a rodent model of stifle arthritis.

Schmidt JR, Krugner-Higby L, Heath TD, Sullivan R, Smith LJ.

J Am Assoc Lab Anim Sci. 2011 Jul;50(4):507-12.


Experimental pharmacodynamics and analgesic efficacy of liposome-encapsulated hydromorphone in dogs.

Krugner-Higby L, Smith L, Schmidt B, Wunsch L, Smetana A, Brown C, Heath TD.

J Am Anim Hosp Assoc. 2011 May-Jun;47(3):185-95. doi: 10.5326/JAAHA-MS-5599. Epub 2011 Apr 15.


Global issues in drug development for Alzheimer's disease.

Doody RS, Cole PE, Miller DS, Siemers E, Black R, Feldman H, Schindler R, Graham S, Heath T, Khachaturian AS, Evans R, Carrillo MC.

Alzheimers Dement. 2011 Mar;7(2):197-207. doi: 10.1016/j.jalz.2011.01.001.


Pharmacokinetics and behavioral effects of liposomal hydromorphone suitable for perioperative use in rhesus macaques.

Krugner-Higby L, KuKanich B, Schmidt B, Heath TD, Brown C.

Psychopharmacology (Berl). 2011 Aug;216(4):511-23. doi: 10.1007/s00213-011-2239-y. Epub 2011 Mar 15.


In vitro-in vivo extrapolation of CYP2C8-catalyzed paclitaxel 6α-hydroxylation: effects of albumin on in vitro kinetic parameters and assessment of interindividual variability in predicted clearance.

Wattanachai N, Polasek TM, Heath TM, Uchaipichat V, Tassaneeyakul W, Tassaneeyakul W, Miners JO.

Eur J Clin Pharmacol. 2011 Aug;67(8):815-24. doi: 10.1007/s00228-011-1001-z. Epub 2011 Feb 9.


Pressure ulcers in cancer palliative care patients.

Hendrichova I, Castelli M, Mastroianni C, Piredda M, Mirabella F, Surdo L, De Marinis MG, Heath T, Casale G.

Palliat Med. 2010 Oct;24(7):669-73. doi: 10.1177/0269216310376119. Epub 2010 Jul 21. Review.


A mathematical relationship for hydromorphone loading into liposomes with trans-membrane ammonium sulfate gradients.

Tu S, McGinnis T, Krugner-Higby L, Heath TD.

J Pharm Sci. 2010 Jun;99(6):2672-80. doi: 10.1002/jps.22017.


Evaluation of liposome-encapsulated butorphanol tartrate for alleviation of experimentally induced arthritic pain in green-cheeked conures (Pyrrhura molinae).

Paul-Murphy JR, Krugner-Higby LA, Tourdot RL, Sladky KK, Klauer JM, Keuler NS, Brown CS, Heath TD.

Am J Vet Res. 2009 Oct;70(10):1211-9. doi: 10.2460/ajvr.70.10.1211.


Analgesic effects of carprofen and liposome-encapsulated butorphanol tartrate in Hispaniolan parrots (Amazona ventralis) with experimentally induced arthritis.

Paul-Murphy JR, Sladky KK, Krugner-Higby LA, Stading BR, Klauer JM, Keuler NS, Brown CS, Heath TD.

Am J Vet Res. 2009 Oct;70(10):1201-10. doi: 10.2460/ajvr.70.10.1201.


Evaluation of phospholipid and liposomal S-adenosyl methionine for the treatment of liver injury in a murine model.

Wagner EJ, Brown CS, Mather JR, Scholcoff C, Krugner-Higby L, Heath TD.

J Pharm Sci. 2010 Apr;99(4):1800-9. doi: 10.1002/jps.21950.


Endogenous ethanolamide analysis in human plasma using HPLC tandem MS with electrospray ionization.

Palandra J, Prusakiewicz J, Ozer JS, Zhang Y, Heath TG.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jul 15;877(22):2052-60. doi: 10.1016/j.jchromb.2009.05.043. Epub 2009 May 28.


Pharmacokinetics and behavioral effects of an extended-release, liposome-encapsulated preparation of oxymorphone in rhesus macaques.

Krugner-Higby L, KuKanich B, Schmidt B, Heath TD, Brown C, Smith LJ.

J Pharmacol Exp Ther. 2009 Jul;330(1):135-41. doi: 10.1124/jpet.108.150052. Epub 2009 Apr 7.


Renal organic anion transporter-mediated drug-drug interaction between gemcabene and quinapril.

Yuan H, Feng B, Yu Y, Chupka J, Zheng JY, Heath TG, Bond BR.

J Pharmacol Exp Ther. 2009 Jul;330(1):191-7. doi: 10.1124/jpet.108.149476. Epub 2009 Apr 6.


Application of stable isotope methodology in the evaluation of the pharmacokinetics of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride in rats.

Yamazaki S, Toth LN, Kimoto E, Bower J, Skaptason J, Romero D, Heath TG.

Drug Metab Dispos. 2009 May;37(5):937-45. doi: 10.1124/dmd.108.025478. Epub 2009 Feb 23.


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