Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 225

1.

Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells associate with clinical outcomes in NHL.

Rossi J, Paczkowski P, Shen YW, Morse K, Flynn B, Kaiser A, Ng C, Gallatin K, Cain T, Fan R, Mackay S, Heath JR, Rosenberg SA, Kochenderfer JN, Zhou J, Bot A.

Blood. 2018 Jun 12. pii: blood-2018-01-828343. doi: 10.1182/blood-2018-01-828343. [Epub ahead of print]

PMID:
29895668
2.

Correction to A Chemically Synthesized Capture Agent Enables the Selective, Sensitive, and Robust Electrochemical Detection of Anthrax Protective Antigen.

Farrow B, Hong SA, Romero EC, Lai B, Coppock MB, Deyle KM, Finch AS, Stratis-Cullum DN, Agnew HD, Yang S, Heath JR.

ACS Nano. 2018 May 22;12(5):5066. doi: 10.1021/acsnano.8b03441. Epub 2018 May 11. No abstract available.

PMID:
29749728
3.

Modulating the Folding Landscape of Superoxide Dismutase 1 with Targeted Molecular Binders.

Bunck DN, Atsavapranee B, Museth AK, VanderVelde D, Heath JR.

Angew Chem Int Ed Engl. 2018 May 22;57(21):6212-6215. doi: 10.1002/anie.201802269. Epub 2018 Apr 25.

PMID:
29645329
4.

Corrigendum: Epitope Targeting of Tertiary Protein Structure Enables Target-Guided Synthesis of a Potent In-Cell Inhibitor of Botulinum Neurotoxin.

Farrow B, Wong M, Malette J, Lai B, Deyle KM, Das S, Nag A, Agnew HD, Heath JR.

Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1439. doi: 10.1002/anie.201712967. No abstract available.

PMID:
29377421
5.

A kinetic investigation of interacting, stimulated T cells identifies conditions for rapid functional enhancement, minimal phenotype differentiation, and improved adoptive cell transfer tumor eradication.

Zhou J, Bethune MT, Malkova N, Sutherland AM, Comin-Anduix B, Su Y, Baltimore D, Ribas A, Heath JR.

PLoS One. 2018 Jan 23;13(1):e0191634. doi: 10.1371/journal.pone.0191634. eCollection 2018.

6.

Epitope-Targeted Macrocyclic Peptide Ligand with Picomolar Cooperative Binding to Interleukin-17F.

Lai BT, Wilson JA, Malette Loredo J, Pitram SM, LaBerge NA, Heath JR, Agnew HD.

Chemistry. 2018 Mar 12;24(15):3760-3767. doi: 10.1002/chem.201704752. Epub 2018 Feb 19.

PMID:
29319889
7.

Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.

Su Y, Wei W, Robert L, Xue M, Tsoi J, Garcia-Diaz A, Homet Moreno B, Kim J, Ng RH, Lee JW, Koya RC, Comin-Anduix B, Graeber TG, Ribas A, Heath JR.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13679-13684. doi: 10.1073/pnas.1712064115. Epub 2017 Dec 11.

8.

High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients.

Tang Y, Wang Z, Li Z, Kim J, Deng Y, Li Y, Heath JR, Wei W, Lu S, Shi Q.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2544-2549. doi: 10.1073/pnas.1612229114. Epub 2017 Feb 21. Erratum in: Proc Natl Acad Sci U S A. 2017 Apr 4;114(14 ):E2983.

9.

Domain-swapped T cell receptors improve the safety of TCR gene therapy.

Bethune MT, Gee MH, Bunse M, Lee MS, Gschweng EH, Pagadala MS, Zhou J, Cheng D, Heath JR, Kohn DB, Kuhns MS, Uckert W, Baltimore D.

Elife. 2016 Nov 8;5. pii: e19095. doi: 10.7554/eLife.19095.

10.

Protein catalyzed capture agents with tailored performance for in vitro and in vivo applications.

Coppock MB, Warner CR, Dorsey B, Orlicki JA, Sarkes DA, Lai BT, Pitram SM, Rohde RD, Malette J, Wilson JA, Kearney P, Fang KC, Law SM, Candelario SL, Farrow B, Finch AS, Agnew HD, Heath JR, Stratis-Cullum DN.

Biopolymers. 2017 Mar;108(2). doi: 10.1002/bip.22934.

PMID:
27539157
11.

Harry Kroto (1939-2016).

Heath JR, Curl RF.

Nature. 2016 May 26;533(7604):470. doi: 10.1038/533470a. No abstract available.

PMID:
27225112
12.

Intercellular signaling through secreted proteins induces free-energy gradient-directed cell movement.

Kravchenko-Balasha N, Shin YS, Sutherland A, Levine RD, Heath JR.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5520-5. doi: 10.1073/pnas.1602171113. Epub 2016 May 2.

13.

Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma.

Wei W, Shin YS, Xue M, Matsutani T, Masui K, Yang H, Ikegami S, Gu Y, Herrmann K, Johnson D, Ding X, Hwang K, Kim J, Zhou J, Su Y, Li X, Bonetti B, Chopra R, James CD, Cavenee WK, Cloughesy TF, Mischel PS, Heath JR, Gini B.

Cancer Cell. 2016 Apr 11;29(4):563-573. doi: 10.1016/j.ccell.2016.03.012.

14.

A Thermodynamic-Based Interpretation of Protein Expression Heterogeneity in Different Glioblastoma Multiforme Tumors Identifies Tumor-Specific Unbalanced Processes.

Kravchenko-Balasha N, Johnson H, White FM, Heath JR, Levine RD.

J Phys Chem B. 2016 Jul 7;120(26):5990-7. doi: 10.1021/acs.jpcb.6b01692. Epub 2016 Apr 12.

15.

Supramolecular Probes for Assessing Glutamine Uptake Enable Semi-Quantitative Metabolic Models in Single Cells.

Xue M, Wei W, Su Y, Johnson D, Heath JR.

J Am Chem Soc. 2016 Mar 9;138(9):3085-93. doi: 10.1021/jacs.5b12187. Epub 2016 Feb 26.

16.

Degradation of Akt using protein-catalyzed capture agents.

Henning RK, Varghese JO, Das S, Nag A, Tang G, Tang K, Sutherland AM, Heath JR.

J Pept Sci. 2016 Apr;22(4):196-200. doi: 10.1002/psc.2858. Epub 2016 Feb 16.

17.

Quantitative assessments of glycolysis from single cells.

Shin YS, Kim J, Johnson D, Dooraghi AA, Mai WX, Ta L, Chatziioannou AF, Phelps ME, Nathanson DA, Heath JR.

Technology (Singap World Sci). 2015 Jun;3(4):172-178. Epub 2015 Jun 25.

18.

Critical Points in Tumorigenesis: A Carcinogen-Initiated Phase Transition Analyzed via Single-Cell Proteomics.

Poovathingal SK, Kravchenko-Balasha N, Shin YS, Levine RD, Heath JR.

Small. 2016 Mar;12(11):1425-31. doi: 10.1002/smll.201501178. Epub 2016 Jan 18.

19.

Single-cell analysis tools for drug discovery and development.

Heath JR, Ribas A, Mischel PS.

Nat Rev Drug Discov. 2016 Mar;15(3):204-16. doi: 10.1038/nrd.2015.16. Epub 2015 Dec 16. Review.

20.

Correction to "Modeling Dioxygen Reduction at Multicopper Oxidase Cathodes".

Agbo P, Heath JR, Gray HB.

J Am Chem Soc. 2015 Dec 23;137(50):15978. doi: 10.1021/jacs.5b11603. Epub 2015 Dec 10. No abstract available.

PMID:
26654090
21.

Nanotechnologies for biomedical science and translational medicine.

Heath JR.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14436-43. doi: 10.1073/pnas.1515202112. Review.

22.

A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands.

Das S, Nag A, Liang J, Bunck DN, Umeda A, Farrow B, Coppock MB, Sarkes DA, Finch AS, Agnew HD, Pitram S, Lai B, Yu MB, Museth AK, Deyle KM, Lepe B, Rodriguez-Rivera FP, McCarthy A, Alvarez-Villalonga B, Chen A, Heath J, Stratis-Cullum DN, Heath JR.

Angew Chem Int Ed Engl. 2015 Nov 2;54(45):13219-24. doi: 10.1002/anie.201505243. Epub 2015 Sep 17.

23.

Epitope targeting of tertiary protein structure enables target-guided synthesis of a potent in-cell inhibitor of botulinum neurotoxin.

Farrow B, Wong M, Malette J, Lai B, Deyle KM, Das S, Nag A, Agnew HD, Heath JR.

Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7114-9. doi: 10.1002/anie.201502451. Epub 2015 Apr 29. Erratum in: Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1439.

24.

A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1.

Deyle KM, Farrow B, Qiao Hee Y, Work J, Wong M, Lai B, Umeda A, Millward SW, Nag A, Das S, Heath JR.

Nat Chem. 2015 May;7(5):455-62. doi: 10.1038/nchem.2223. Epub 2015 Apr 13.

25.

Chemical methods for the simultaneous quantitation of metabolites and proteins from single cells.

Xue M, Wei W, Su Y, Kim J, Shin YS, Mai WX, Nathanson DA, Heath JR.

J Am Chem Soc. 2015 Apr 1;137(12):4066-9. doi: 10.1021/jacs.5b00944. Epub 2015 Mar 19.

26.

The influence of water on the optical properties of single-layer molybdenum disulfide.

Varghese JO, Agbo P, Sutherland AM, Brar VW, Rossman GR, Gray HB, Heath JR.

Adv Mater. 2015 May 6;27(17):2734-40. doi: 10.1002/adma.201500555. Epub 2015 Mar 18.

PMID:
25787228
27.

Modeling dioxygen reduction at multicopper oxidase cathodes.

Agbo P, Heath JR, Gray HB.

J Am Chem Soc. 2014 Oct 1;136(39):13882-7. doi: 10.1021/ja5077519. Epub 2014 Sep 17. Erratum in: J Am Chem Soc. 2015 Dec 23;137(50):15978.

PMID:
25188422
28.

Human NK cells licensed by killer Ig receptor genes have an altered cytokine program that modifies CD4+ T cell function.

Lin L, Ma C, Wei B, Aziz N, Rajalingam R, Yusung S, Erlich HA, Trachtenberg EA, Targan SR, McGovern DP, Heath JR, Braun J.

J Immunol. 2014 Jul 15;193(2):940-9. doi: 10.4049/jimmunol.1400093. Epub 2014 Jun 16.

29.

Microfluidics-based single-cell functional proteomics for fundamental and applied biomedical applications.

Yu J, Zhou J, Sutherland A, Wei W, Shin YS, Xue M, Heath JR.

Annu Rev Anal Chem (Palo Alto Calif). 2014;7:275-95. doi: 10.1146/annurev-anchem-071213-020323. Epub 2014 Jun 2. Review.

PMID:
24896308
30.

Glioblastoma cellular architectures are predicted through the characterization of two-cell interactions.

Kravchenko-Balasha N, Wang J, Remacle F, Levine RD, Heath JR.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6521-6. doi: 10.1073/pnas.1404462111. Epub 2014 Apr 14.

31.

Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma.

Chodon T, Comin-Anduix B, Chmielowski B, Koya RC, Wu Z, Auerbach M, Ng C, Avramis E, Seja E, Villanueva A, McCannel TA, Ishiyama A, Czernin J, Radu CG, Wang X, Gjertson DW, Cochran AJ, Cornetta K, Wong DJ, Kaplan-Lefko P, Hamid O, Samlowski W, Cohen PA, Daniels GA, Mukherji B, Yang L, Zack JA, Kohn DB, Heath JR, Glaspy JA, Witte ON, Baltimore D, Economou JS, Ribas A.

Clin Cancer Res. 2014 May 1;20(9):2457-65. doi: 10.1158/1078-0432.CCR-13-3017. Epub 2014 Mar 14.

32.

Conversion of danger signals into cytokine signals by hematopoietic stem and progenitor cells for regulation of stress-induced hematopoiesis.

Zhao JL, Ma C, O'Connell RM, Mehta A, DiLoreto R, Heath JR, Baltimore D.

Cell Stem Cell. 2014 Apr 3;14(4):445-459. doi: 10.1016/j.stem.2014.01.007. Epub 2014 Feb 20.

33.

Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.

Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, Gomez G, Eskin A, Hwang K, Wang J, Masui K, Paucar A, Yang H, Ohashi M, Zhu S, Wykosky J, Reed R, Nelson SF, Cloughesy TF, James CD, Rao PN, Kornblum HI, Heath JR, Cavenee WK, Furnari FB, Mischel PS.

Science. 2014 Jan 3;343(6166):72-6. doi: 10.1126/science.1241328. Epub 2013 Dec 5.

34.

A chemical epitope-targeting strategy for protein capture agents: the serine 474 epitope of the kinase Akt2.

Nag A, Das S, Yu MB, Deyle KM, Millward SW, Heath JR.

Angew Chem Int Ed Engl. 2013 Dec 23;52(52):13975-9. doi: 10.1002/anie.201305882. Epub 2013 Nov 19. No abstract available.

35.

A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera.

Pfeilsticker JA, Umeda A, Farrow B, Hsueh CL, Deyle KM, Kim JT, Lai BT, Heath JR.

PLoS One. 2013 Oct 7;8(10):e76224. doi: 10.1371/journal.pone.0076224. eCollection 2013.

36.

A chemically synthesized capture agent enables the selective, sensitive, and robust electrochemical detection of anthrax protective antigen.

Farrow B, Hong SA, Romero EC, Lai B, Coppock MB, Deyle KM, Finch AS, Stratis-Cullum DN, Agnew HD, Yang S, Heath JR.

ACS Nano. 2013 Oct 22;7(10):9452-60. doi: 10.1021/nn404296k. Epub 2013 Oct 8. Erratum in: ACS Nano. 2018 May 22;12 (5):5066.

PMID:
24063758
37.

Wetting: Contact with what?

Xu K, Heath JR.

Nat Mater. 2013 Oct;12(10):872-3. doi: 10.1038/nmat3763. No abstract available.

PMID:
24056851
38.

The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.

Gini B, Zanca C, Guo D, Matsutani T, Masui K, Ikegami S, Yang H, Nathanson D, Villa GR, Shackelford D, Zhu S, Tanaka K, Babic I, Akhavan D, Lin K, Assuncao A, Gu Y, Bonetti B, Mortensen DS, Xu S, Raymon HK, Cavenee WK, Furnari FB, James CD, Kroemer G, Heath JR, Hege K, Chopra R, Cloughesy TF, Mischel PS.

Clin Cancer Res. 2013 Oct 15;19(20):5722-32. doi: 10.1158/1078-0432.CCR-13-0527. Epub 2013 Sep 12.

39.

Microchip platforms for multiplex single-cell functional proteomics with applications to immunology and cancer research.

Wei W, Shin YS, Ma C, Wang J, Elitas M, Fan R, Heath JR.

Genome Med. 2013 Aug 29;5(8):75. doi: 10.1186/gm479. eCollection 2013. Review.

40.

Fast metabolic response to drug intervention through analysis on a miniaturized, highly integrated molecular imaging system.

Wang J, Hwang K, Braas D, Dooraghi A, Nathanson D, Campbell DO, Gu Y, Sandberg T, Mischel P, Radu C, Chatziioannou AF, Phelps ME, Christofk H, Heath JR.

J Nucl Med. 2013 Oct;54(10):1820-4. doi: 10.2967/jnumed.112.118497. Epub 2013 Aug 26.

41.

Betabox: a beta particle imaging system based on a position sensitive avalanche photodiode.

Dooraghi AA, Vu NT, Silverman RW, Farrell R, Shah KS, Wang J, Heath JR, Chatziioannou AF.

Phys Med Biol. 2013 Jun 7;58(11):3739-53. doi: 10.1088/0031-9155/58/11/3739. Epub 2013 May 8.

42.

Hypoxia induces a phase transition within a kinase signaling network in cancer cells.

Wei W, Shi Q, Remacle F, Qin L, Shackelford DB, Shin YS, Mischel PS, Levine RD, Heath JR.

Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):E1352-60. doi: 10.1073/pnas.1303060110. Epub 2013 Mar 25.

43.

Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy.

Ma C, Cheung AF, Chodon T, Koya RC, Wu Z, Ng C, Avramis E, Cochran AJ, Witte ON, Baltimore D, Chmielowski B, Economou JS, Comin-Anduix B, Ribas A, Heath JR.

Cancer Discov. 2013 Apr;3(4):418-29. doi: 10.1158/2159-8290.CD-12-0383. Epub 2013 Mar 21.

44.

Catalysis of dioxygen reduction by Thermus thermophilus strain HB27 laccase on ketjen black electrodes.

Agbo P, Heath JR, Gray HB.

J Phys Chem B. 2013 Jan 17;117(2):527-34. doi: 10.1021/jp309759g. Epub 2012 Nov 28.

45.

Quantitating cell-cell interaction functions with applications to glioblastoma multiforme cancer cells.

Wang J, Tham D, Wei W, Shin YS, Ma C, Ahmad H, Shi Q, Yu J, Levine RD, Heath JR.

Nano Lett. 2012 Dec 12;12(12):6101-6. doi: 10.1021/nl302748q. Epub 2012 Nov 7.

46.

A microfluidic-based bubble generation platform enables analysis of physical property change in phospholipid surfactant layers by interfacial ozone reaction.

Shin YS, Choi TS, Kim H, Beauchamp JL, Heath JR, Kim HI.

Lab Chip. 2012 Dec 21;12(24):5243-8. doi: 10.1039/c2lc40940b.

47.

Silicon nanowire charge-trap memory incorporating self-assembled iron oxide quantum dots.

Huang RG, Heath JR.

Small. 2012 Nov 19;8(22):3417-21. doi: 10.1002/smll.201200940. Epub 2012 Sep 10.

PMID:
22961957
48.

In situ click chemistry: from small molecule discovery to synthetic antibodies.

Millward SW, Agnew HD, Lai B, Lee SS, Lim J, Nag A, Pitram S, Rohde R, Heath JR.

Integr Biol (Camb). 2013 Jan;5(1):87-95. doi: 10.1039/c2ib20110k. Review.

49.

New directions in cellular therapy of cancer: a summary of the summit on cellular therapy for cancer.

Stroncek DF, Berger C, Cheever MA, Childs RW, Dudley ME, Flynn P, Gattinoni L, Heath JR, Kalos M, Marincola FM, Miller JS, Mostoslavsky G, Powell DJ Jr, Rao M, Restifo NP, Rosenberg SA, O'Shea J, Melief CJ.

J Transl Med. 2012 Mar 15;10:48. doi: 10.1186/1479-5876-10-48.

50.

Designer reagents for mass spectrometry-based proteomics: clickable cross-linkers for elucidation of protein structures and interactions.

Sohn CH, Agnew HD, Lee JE, Sweredoski MJ, Graham RL, Smith GT, Hess S, Czerwieniec G, Loo JA, Heath JR, Deshaies RJ, Beauchamp JL.

Anal Chem. 2012 Mar 20;84(6):2662-9. doi: 10.1021/ac202637n. Epub 2012 Mar 5.

Supplemental Content

Loading ...
Support Center