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Items: 1 to 50 of 68

1.

Contact dependent suppression of CD4 T cell activation and proliferation by B cells activated through IgD cross-linking.

Preciado-Llanes L, Wing JB, Foster RA, Carlring J, Lees A, Read RC, Heath AW.

Immunology. 2014 Sep 20. doi: 10.1111/imm.12389. [Epub ahead of print]

2.

Correlation of group C meningococcal conjugate vaccine response with B- and T-lymphocyte activity.

Wing JB, Smart L, Borrow R, Findlow J, Findlow H, Lees A, Foster RA, Carlring J, Read RC, Heath AW.

PLoS One. 2012;7(2):e31160. doi: 10.1371/journal.pone.0031160. Epub 2012 Feb 8. Erratum in: PLoS One. 2012;7(11). doi:10.1371/annotation/45ca0028-74a1-427d-ba95-3dbd2acc6b80. Foster, Rachel A [added] Carlring, Jennifer [added].

3.

Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.

Carlring J, Szabo MJ, Dickinson R, De Leenheer E, Heath AW.

Blood. 2012 Mar 1;119(9):2056-65. doi: 10.1182/blood-2011-05-355461. Epub 2012 Jan 10.

4.

A novel redox method for rapid production of functional bi-specific antibodies for use in early pilot studies.

Carlring J, De Leenheer E, Heath AW.

PLoS One. 2011;6(7):e22533. doi: 10.1371/journal.pone.0022533. Epub 2011 Jul 21.

5.

Kinetics of immune responses to nasal challenge with meningococcal polysaccharide one year after serogroup-C glycoconjugate vaccination.

Wing JB, Smart L, Borrow R, Findlow J, Findlow H, Heath AW, Read RC.

Clin Infect Dis. 2011 Jun;52(11):1317-23. doi: 10.1093/cid/cir198.

PMID:
21596673
6.

Adult survivors of invasive pneumococcal disease exhibit defective B cell function.

Darton TC, Wing JB, Lees A, Heath AW, Read RC.

Clin Infect Dis. 2011 May;52(9):1133-6. doi: 10.1093/cid/cir126.

7.

CD154-CD40 interactions in the control of murine B cell hematopoiesis.

Carlring J, Altaher HM, Clark S, Chen X, Latimer SL, Jenner T, Buckle AM, Heath AW.

J Leukoc Biol. 2011 May;89(5):697-706. doi: 10.1189/jlb.0310179. Epub 2011 Feb 17.

8.

Functional T-cell deficiency in adolescents who experience serogroup C meningococcal disease despite receiving the meningococcal serogroup C conjugate vaccine.

Foster RA, Carlring J, Lees A, Borrow R, Ramsay M, Kacsmarski E, Miller E, McKendrick MW, Heath AW, Read RC.

Clin Vaccine Immunol. 2010 Jul;17(7):1104-10. doi: 10.1128/CVI.00481-09. Epub 2010 May 12.

9.

CD40mAb adjuvant induces a rapid antibody response that may be beneficial in post-exposure prophylaxis.

Bhagawati-Prasad VN, De Leenheer E, Keefe NP, Ryan LA, Carlring J, Heath AW.

J Immune Based Ther Vaccines. 2010 Feb 4;8:1. doi: 10.1186/1476-8518-8-1.

10.

B-cell-T-cell activation and interaction in common variable immunodeficiency.

Rezaei N, Wing JB, Aghamohammadi A, Carlring J, Lees A, Asgarian-Omran H, Pourpak Z, Sarrafnejad A, Kardar GA, Shahrestani T, Masoumi F, Zare A, Saghafi S, Sarrafzadeh S, Foster RA, Heath AW, Read RC.

Hum Immunol. 2010 Apr;71(4):355-62. doi: 10.1016/j.humimm.2010.01.019. Epub 2010 Feb 19.

PMID:
20097245
11.

Evidence of a functional B-cell immunodeficiency in adults who experience serogroup C meningococcal disease.

Foster RA, Carlring J, McKendrick MW, Lees A, Borrow R, Read RC, Heath AW.

Clin Vaccine Immunol. 2009 May;16(5):692-8. doi: 10.1128/CVI.00485-08. Epub 2009 Mar 11.

12.

Liposomal co-entrapment of CD40mAb induces enhanced IgG responses against bacterial polysaccharide and protein.

Hatzifoti C, Bacon A, Marriott H, Laing P, Heath AW.

PLoS One. 2008 Jun 4;3(6):e2368. doi: 10.1371/journal.pone.0002368.

13.

CD40-mediated enhancement of immune responses against three forms of influenza vaccine.

Hatzifoti C, Heath AW.

Immunology. 2007 Sep;122(1):98-106. Epub 2007 Apr 30.

14.

Fusion of antigen to Fas-ligand in a DNA vaccine enhances immunogenicity.

Nimal S, Thomas MS, Heath AW.

Vaccine. 2007 Mar 8;25(12):2306-15. Epub 2006 Dec 11.

PMID:
17239500
15.

Antibodies against cell surface antigens as very potent immunological adjuvants.

Barr T, Carlring J, Hatzifoti C, Heath AW.

Vaccine. 2006 Apr 12;24 Suppl 2:S2-20-1.

PMID:
16823910
16.

Co-stimulatory agonists as immunological adjuvants.

Barr TA, Carlring J, Heath AW.

Vaccine. 2006 Apr 24;24(17):3399-407. Epub 2006 Feb 24. Review.

PMID:
16530301
17.

Enhancement of immune responses to an HIV gp120 DNA vaccine by fusion to TNF alpha cDNA.

Nimal S, Heath AW, Thomas MS.

Vaccine. 2006 Apr 12;24(16):3298-308. Epub 2006 Jan 20.

PMID:
16464521
18.

An interferon gamma-gp120 fusion delivered as a DNA vaccine induces enhanced priming.

Nimal S, McCormick AL, Thomas MS, Heath AW.

Vaccine. 2005 Jun 10;23(30):3984-90. Epub 2005 Apr 2.

PMID:
15917120
20.

Adjuvanticity of anti-cD40 in vaccine development.

Cairing J, Barr T, Heath AW.

Curr Opin Mol Ther. 2005 Feb;7(1):73-7. Review.

PMID:
15732532
21.

CD40 antibody as an adjuvant induces enhanced T cell responses.

Carlring J, Barr TA, McCormick AL, Heath AW.

Vaccine. 2004 Sep 3;22(25-26):3323-8.

PMID:
15308355
22.

A potent adjuvant effect of CD40 antibody attached to antigen.

Barr TA, McCormick AL, Carlring J, Heath AW.

Immunology. 2003 May;109(1):87-92.

23.
24.
25.

Immunization with an interferon-gamma-gp120 fusion protein induces enhanced immune responses to human immunodeficiency virus gp120.

McCormick AL, Thomas MS, Heath AW.

J Infect Dis. 2001 Dec 1;184(11):1423-30. Epub 2001 Nov 13.

PMID:
11709784
26.

Recent advances in vaccinology.

Heath AW.

Curr Opin Pharmacol. 2001 Aug;1(4):425-30. Review.

PMID:
11710743
27.

Stimulation of dendritic cells via CD40 enhances immune responses to Mycobacterium tuberculosis infection.

Demangel C, Palendira U, Feng CG, Heath AW, Bean AG, Britton WJ.

Infect Immun. 2001 Apr;69(4):2456-61.

29.
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31.

Antibody responses, cytokine levels and protection of mice immunised with HSV-2 antigens formulated into NISV or ISCOM delivery systems.

Mohamedi SA, Brewer JM, Alexander J, Heath AW, Jennings R.

Vaccine. 2000 Apr 14;18(20):2083-94.

PMID:
10715522
32.
33.
34.
35.

Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.

Randall TD, Heath AW, Santos-Argumedo L, Howard MC, Weissman IL, Lund FE.

Immunity. 1998 Jun;8(6):733-42.

36.

Humoral response to HSV-1 subunit vaccines--a statistical analysis.

Simms JR, Heath AW, Richardson VJ, Jennings R.

Dev Biol Stand. 1998;92:335-40.

PMID:
9554289
37.

A novel method for enhancement of T independent responses.

Dullforce P, Sutton D, Heath AW.

Dev Biol Stand. 1998;92:195-8.

PMID:
9554275
38.

Adjuvants and delivery systems for viral vaccines--mechanisms and potential.

Jennings R, Simms JR, Heath AW.

Dev Biol Stand. 1998;92:19-28. Review.

PMID:
9554256
39.

Enhancement of T cell-independent immune responses in vivo by CD40 antibodies.

Dullforce P, Sutton DC, Heath AW.

Nat Med. 1998 Jan;4(1):88-91.

PMID:
9427612
40.

Enhancement of immunogenicity of recombinant antigens by production of a cytokine-antigen fusion protein for vaccination.

McCormick AL, Thomas MS, Heath AW.

Biochem Soc Trans. 1997 May;25(2):297S. No abstract available.

PMID:
9191341
41.

Large scale comparison of adjuvant effects on immunogenicity and protection in a herpes simplex virus type 1 vaccination model.

Simms JR, Heath AW, Richardson VJ, Jennings R.

Biochem Soc Trans. 1997 May;25(2):272S. No abstract available.

PMID:
9191316
42.

CD40 signaling induces interleukin-4-independent IgE switching in vivo.

Ferlin WG, Severinson E, Ström L, Heath AW, Coffman RL, Ferrick DA, Howard MC.

Eur J Immunol. 1996 Dec;26(12):2911-5.

PMID:
8977285
43.

Differential activation of the ERK, JNK, and p38 mitogen-activated protein kinases by CD40 and the B cell antigen receptor.

Sutherland CL, Heath AW, Pelech SL, Young PR, Gold MR.

J Immunol. 1996 Oct 15;157(8):3381-90.

PMID:
8871635
44.
45.

The effect of antigen dose on CD4+ T helper cell phenotype development in a T cell receptor-alpha beta-transgenic model.

Hosken NA, Shibuya K, Heath AW, Murphy KM, O'Garra A.

J Exp Med. 1995 Nov 1;182(5):1579-84.

46.

CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regular of CD38 induced signal transduction.

Santos-Argumedo L, Lund FE, Heath AW, Solvason N, Wu WW, Grimaldi JC, Parkhouse RM, Howard M.

Int Immunol. 1995 Feb;7(2):163-70.

PMID:
7734414
47.

Cytokines as adjuvants in immunocompromised hosts.

Heath AW.

Int J Clin Lab Res. 1995;25(1):25-8. Review.

PMID:
7787206
48.

Cytokines as immunological adjuvants.

Heath AW.

Pharm Biotechnol. 1995;6:645-58. Review. No abstract available.

PMID:
7551241
49.

Monoclonal antibodies to murine CD40 define two distinct functional epitopes.

Heath AW, Wu WW, Howard MC.

Eur J Immunol. 1994 Aug;24(8):1828-34.

PMID:
7519997
50.

Antibodies to murine CD40 protect normal and malignant B cells from induced growth arrest.

Santos-Argumedo L, Gordon J, Heath AW, Howard M.

Cell Immunol. 1994 Jul;156(2):272-85.

PMID:
7517793

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