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Items: 36

1.

Emetic, central nervous system, and pulmonary activities of rolipram in the dog.

Heaslip RJ, Evans DY.

Eur J Pharmacol. 1995 Nov 24;286(3):281-90.

PMID:
8608790
2.

Phospholipid regulation of a cyclic AMP-specific phosphodiesterase (PDE4) from U937 cells.

DiSanto ME, Glaser KB, Heaslip RJ.

Cell Signal. 1995 Nov;7(8):827-35.

PMID:
8593251
3.

Pulmonary antiallergic and antiinflammatory effects of a novel, orally-active phosphodiesterase IV inhibitor (WAY-127093B) in guinea pigs and rats.

Howell RE, Woeppel SL, Howell DE, Rubin EB, Jenkins LP, Golankiewicz JM, Lombardo LJ, Heaslip RJ.

Inflamm Res. 1995 Aug;44 Suppl 2:S172-3. No abstract available.

PMID:
8548383
4.

Rolipram inhibition of phosphodiesterase-4 activation.

DiSanto ME, Heaslip RJ.

Eur J Pharmacol. 1995 Jul 18;290(2):169-72.

PMID:
8575533
5.

Multiple cyclic nucleotide phosphodiesterases.

Beavo JA, Conti M, Heaslip RJ.

Mol Pharmacol. 1994 Sep;46(3):399-405. No abstract available.

PMID:
7935318
6.

Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641.

Heaslip RJ, Lombardo LJ, Golankiewicz JM, Ilsemann BA, Evans DY, Sickels BD, Mudrick JK, Bagli J, Weichman BM.

J Pharmacol Exp Ther. 1994 Feb;268(2):888-96.

PMID:
8114002
7.

Identification and stabilization of large molecular weight PDE-IVs from U937 cells.

DiSanto ME, Heaslip RJ.

Biochem Biophys Res Commun. 1993 Dec 30;197(3):1126-31.

PMID:
8280127
8.

Anti-leukotriene effects of WY-50,295 tromethamine in isolated guinea pig pulmonary tissues.

Heaslip RJ, Grimes D, Berkenkopf JW, Ilsemann BA, Sickels BD, Weichman BM.

Eur J Pharmacol. 1993 Apr 6;234(2-3):247-54.

PMID:
8482329
9.

Effects of rolipram and CI-930 on IL-2 mRNA transcription in human Jurkat cells.

Lewis GM, Caccese RG, Heaslip RJ, Bansbach CC.

Agents Actions. 1993;39 Spec No:C89-92.

PMID:
8273597
10.
11.

Bronchial vs. cardiovascular activities of selective phosphodiesterase inhibitors in the anesthetized beta-blocked dog.

Heaslip RJ, Buckley SK, Sickels BD, Grimes D.

J Pharmacol Exp Ther. 1991 May;257(2):741-7.

PMID:
2033517
12.

WY-50,295 tromethamine: a novel inhibitor of leukotriene-mediated reactions.

Weichman BM, Berkenkopf JW, Grimes D, Heaslip RJ, Sturm RJ, Chang JY.

Adv Prostaglandin Thromboxane Leukot Res. 1991;21A:477-80. Review. No abstract available.

PMID:
1847784
13.

WY-50, 295 tromethamine: an orally active 5-lipoxygenase inhibitor with anti-allergic activity.

Weichman BM, Berkenkopf JW, Chang JY, Heaslip RJ, Kreft AF, Lewis AJ, Musser JH, Grimes D.

Agents Actions Suppl. 1991;34:201-9.

PMID:
1793064
14.

Evidence that prostaglandins can contract the rat aorta via a novel protein kinase C-dependent mechanism.

Heaslip RJ, Sickels BD.

J Pharmacol Exp Ther. 1989 Jul;250(1):44-51.

PMID:
2545867
15.

Structure-activity relationships of 1H-indole-7-carboxamides as a novel series of selective alpha 1-adrenoceptor agonists.

Rimele TJ, Caggiano TJ, Buckley SK, Dustman WJ, Schmid J, Heaslip RJ, Grimes D, Asselin AA.

Arzneimittelforschung. 1989 Feb;39(2):187-95.

PMID:
2567168
16.

Comparison of the beta-adrenoceptor affinity and selectivity of cetamolol, atenolol, betaxolol, and ICI-118,551.

Rimele TJ, Henry DE, Giesa FR, Buckley SK, Geiger G, Heaslip RJ, Lee DK, Grimes D.

J Cardiovasc Pharmacol. 1988 Aug;12(2):208-17.

PMID:
2459552
17.

Intracellular mechanisms of contraction in the hypertensive and normotensive rat aortas.

Heaslip RJ, Sickels BD.

Eur J Pharmacol. 1988 May 20;150(1-2):189-91.

PMID:
3165344
18.

Interaction of neutrophils with vascular smooth muscle: identification of a neutrophil-derived relaxing factor.

Rimele TJ, Sturm RJ, Adams LM, Henry DE, Heaslip RJ, Weichman BM, Grimes D.

J Pharmacol Exp Ther. 1988 Apr;245(1):102-11.

PMID:
3129547
19.

Co-regulation of tracheal tone by cyclic AMP- and cyclic GMP-dependent mechanisms.

Heaslip RJ, Giesa FR, Rimele TJ, Grimes D.

J Pharmacol Exp Ther. 1987 Dec;243(3):1018-26.

PMID:
2826752
20.

In vitro isolated tissue studies with atiprosin (AY-28,228): a new antihypertensive compound.

Grimes D, Rimele TJ, Henry DE, Heaslip RJ, Geiger G, Lee DK, Metcalf G.

J Cardiovasc Pharmacol. 1987 Sep;10(3):249-58.

PMID:
2444771
21.

Demonstration of the beta 2-adrenoceptor intrinsic efficacy of AY-28,925 using the PGF2 alpha-contracted guinea-pig trachea.

Heaslip RJ, Giesa FR, Rimele TJ, Grimes D.

Eur J Pharmacol. 1987 Jun 4;137(2-3):179-84.

PMID:
2886349
22.

Tissue-dependent alpha adrenoceptor activity of buspirone and related compounds.

Rimele TJ, Henry DE, Lee DK, Geiger G, Heaslip RJ, Grimes D.

J Pharmacol Exp Ther. 1987 Jun;241(3):771-8.

PMID:
3037069
23.

In vitro characterization of the adrenoceptor activity of AY-28,925.

Rimele TJ, Heaslip RJ, Lee DK, Grimes D.

J Pharmacol Exp Ther. 1986 Oct;239(1):1-8.

PMID:
2876089
24.

Sensitivity of the PGF2 alpha-versus carbachol-contracted trachea to relaxation by salbutamol, forskolin and prenalterol.

Heaslip RJ, Giesa FR, Rimele TJ, Grimes D.

Eur J Pharmacol. 1986 Aug 22;128(1-2):73-9.

PMID:
3019740
25.

Indole-phenol bioisosterism. Synthesis and antihypertensive activity of a pyrrolo analogue of labetalol.

Asselin AA, Humber LG, Crosilla D, Oshiro G, Wojdan A, Grimes D, Heaslip RJ, Rimele TJ, Shaw CC.

J Med Chem. 1986 Jun;29(6):1009-15.

PMID:
3012084
26.

Regulation of actomyosin ATPase in smooth muscle.

Chacko S, Heaslip RJ, Fillers WS, Kaminski EA.

Prog Clin Biol Res. 1986;219:169-85. Review.

PMID:
2947244
27.

The effect of leiotonin fraction on stably phosphorylated smooth muscle myosin.

Chacko S, Heaslip RJ, Ebashi S.

Biochem Biophys Res Commun. 1985 Jul 16;130(1):286-92.

PMID:
3161498
28.
32.
34.
35.

Synthesis and preliminary pharmacological evaluation of asymmetric chloroquine analogues.

Witiak DT, Grattan DA, Heaslip RJ, Rahwan RG.

J Med Chem. 1981 Jun;24(6):712-7.

PMID:
7252981
36.

Uterine relaxant effects of mono- and dibenzyloxyindanpropionic acids.

Heaslip RJ, Rahwan RG, Hassan AM, Witiak DT.

Res Commun Chem Pathol Pharmacol. 1981 May;32(2):251-9.

PMID:
7244363

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