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Items: 1 to 50 of 225

1.

Improved engraftment with minimal graft-versus-host disease after major histocompatibility complex-mismatched cord blood transplantation with photochemically treated donor lymphocytes.

Kanathezhath B, Mizokami M, Stanislaus S, Hounshell C, Neumayr L, Guo H, Hearst JE, Walters MC, Kuypers FA.

Exp Biol Med (Maywood). 2011 Apr 1;236(4):492-504. doi: 10.1258/ebm.2011.010216. Epub 2011 Mar 31.

PMID:
21454375
2.

Quantitative analysis of DNA interstrand cross-links and monoadducts formed in human cells induced by psoralens and UVA irradiation.

Lai C, Cao H, Hearst JE, Corash L, Luo H, Wang Y.

Anal Chem. 2008 Nov 15;80(22):8790-8. doi: 10.1021/ac801520m. Epub 2008 Oct 24.

3.

LC-MS/MS for the detection of DNA interstrand cross-links formed by 8-methoxypsoralen and UVA irradiation in human cells.

Cao H, Hearst JE, Corash L, Wang Y.

Anal Chem. 2008 Apr 15;80(8):2932-8. doi: 10.1021/ac7023969. Epub 2008 Mar 7.

PMID:
18324836
4.

Stem cell transplantation with S-59 photochemically treated T-cell add-backs to establish allochimerism in murine thalassemia.

Kuypers FA, Watson G, Sage E, Walters MC, Hamrick J, Hearst JE.

Ann N Y Acad Sci. 2005;1054:214-22.

PMID:
16339668
5.

Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity.

Brockstedt DG, Bahjat KS, Giedlin MA, Liu W, Leong M, Luckett W, Gao Y, Schnupf P, Kapadia D, Castro G, Lim JY, Sampson-Johannes A, Herskovits AA, Stassinopoulos A, Bouwer HG, Hearst JE, Portnoy DA, Cook DN, Dubensky TW Jr.

Nat Med. 2005 Aug;11(8):853-60. Epub 2005 Jul 24.

PMID:
16041382
6.

DNA repair defects channel interstrand DNA cross-links into alternate recombinational and error-prone repair pathways.

Saffran WA, Ahmed S, Bellevue S, Pereira G, Patrick T, Sanchez W, Thomas S, Alberti M, Hearst JE.

J Biol Chem. 2004 Aug 27;279(35):36462-9. Epub 2004 Jun 22.

7.

Allogeneic T cells treated with amotosalen prevent lethal cytomegalovirus disease without producing graft-versus-host disease following bone marrow transplantation.

Roback JD, Hossain MS, Lezhava L, Gorechlad JW, Alexander SA, Jaye DL, Mittelstaedt S, Talib S, Hearst JE, Hillyer CD, Waller EK.

J Immunol. 2003 Dec 1;171(11):6023-31.

8.
9.

Recombinational and mutagenic repair of psoralen interstrand cross-links in Saccharomyces cerevisiae.

Greenberg RB, Alberti M, Hearst JE, Chua MA, Saffran WA.

J Biol Chem. 2001 Aug 24;276(34):31551-60. Epub 2001 Jun 4.

10.

The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions.

Eichman BF, Mooers BH, Alberti M, Hearst JE, Ho PS.

J Mol Biol. 2001 Apr 20;308(1):15-26.

PMID:
11302703
11.

DNA interstrand cross-links induce futile repair synthesis in mammalian cell extracts.

Mu D, Bessho T, Nechev LV, Chen DJ, Harris TM, Hearst JE, Sancar A.

Mol Cell Biol. 2000 Apr;20(7):2446-54.

13.

Rhodobacter capsulatus DNA topoisomerase I purification and characterization.

Alkorta I, Park C, Kong J, Garbisu C, Alberti M, Pon N, Hearst JE.

Arch Biochem Biophys. 1999 Feb 1;362(1):123-30.

PMID:
9917336
14.

A simple mechanism for the avoidance of entanglement during chromosome replication.

Hearst JE, Kauffman L, McClain WM.

Trends Genet. 1998 Jun;14(6):244-7. Review.

PMID:
9635408
15.

Photochemical inactivation of viruses and bacteria in platelet concentrates by use of a novel psoralen and long-wavelength ultraviolet light.

Lin L, Cook DN, Wiesehahn GP, Alfonso R, Behrman B, Cimino GD, Corten L, Damonte PB, Dikeman R, Dupuis K, Fang YM, Hanson CV, Hearst JE, Lin CY, Londe HF, Metchette K, Nerio AT, Pu JT, Reames AA, Rheinschmidt M, Tessman J, Isaacs ST, Wollowitz S, Corash L.

Transfusion. 1997 Apr;37(4):423-35.

PMID:
9111281
16.

Carotenoids 2: Genetics and molecular biology of carotenoid pigment biosynthesis.

Armstrong GA, Hearst JE.

FASEB J. 1996 Feb;10(2):228-37. Review.

PMID:
8641556
17.

The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals.

Ma D, Alberti M, Lynch C, Nikaido H, Hearst JE.

Mol Microbiol. 1996 Jan;19(1):101-12.

PMID:
8821940
18.

Spin-labeled psoralen probes for the study of DNA dynamics.

Spielmann HP, Chi DY, Hunt NG, Klein MP, Hearst JE.

Biochemistry. 1995 Nov 14;34(45):14801-14.

PMID:
7578089
19.

Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics.

Spielmann HP, Dwyer TJ, Hearst JE, Wemmer DE.

Biochemistry. 1995 Oct 10;34(40):12937-53.

PMID:
7548052
20.

Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus.

Yokota H, van den Engh G, Hearst JE, Sachs RK, Trask BJ.

J Cell Biol. 1995 Sep;130(6):1239-49. Erratum in: J Cell Biol 1999 Dec 27;147(7):1583.

21.

Identifying the killer in cystic fibrosis.

Hearst JE, Elliott KE.

Nat Med. 1995 Jul;1(7):626-7. No abstract available.

PMID:
7585137
22.

The structure of photolyase: using photon energy for DNA repair.

Hearst JE.

Science. 1995 Jun 30;268(5219):1858-9. Review. No abstract available.

PMID:
7604259
23.

Genes acrA and acrB encode a stress-induced efflux system of Escherichia coli.

Ma D, Cook DN, Alberti M, Pon NG, Nikaido H, Hearst JE.

Mol Microbiol. 1995 Apr;16(1):45-55.

PMID:
7651136
24.

A random-walk/giant-loop model for interphase chromosomes.

Sachs RK, van den Engh G, Trask B, Yokota H, Hearst JE.

Proc Natl Acad Sci U S A. 1995 Mar 28;92(7):2710-4.

25.

DNA structural reorganization upon conversion of a psoralen furan-side monoadduct to an interstrand cross-link: implications for DNA repair.

Spielmann HP, Dwyer TJ, Sastry SS, Hearst JE, Wemmer DE.

Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2345-9.

26.

Efflux pumps and drug resistance in gram-negative bacteria.

Ma D, Cook DN, Hearst JE, Nikaido H.

Trends Microbiol. 1994 Dec;2(12):489-93.

PMID:
7889326
27.

Functional assignment of Erwinia herbicola Eho10 carotenoid genes expressed in Escherichia coli.

Hundle B, Alberti M, Nievelstein V, Beyer P, Kleinig H, Armstrong GA, Burke DH, Hearst JE.

Mol Gen Genet. 1994 Nov 15;245(4):406-16.

PMID:
7808389
28.

Luminescence energy transfer using a terbium chelate: improvements on fluorescence energy transfer.

Selvin PR, Hearst JE.

Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):10024-8.

29.

Determination of the average orientation of DNA in the octopus sperm Eledone cirrhossa through polarized light scattering.

Shapiro DB, Maestre MF, McClain WM, Hull PG, Shi Y, Quinby-Hunt MS, Hearst JE, Hunt AJ.

Appl Opt. 1994 Aug 20;33(24):5733-44. doi: 10.1364/AO.33.005733.

PMID:
20935975
30.
32.

Chromosome condensation: amorphous or structured.

Hearst JE.

Biophys J. 1994 Mar;66(3 Pt 1):551. No abstract available.

33.

Molecular cloning and characterization of acrA and acrE genes of Escherichia coli.

Ma D, Cook DN, Alberti M, Pon NG, Nikaido H, Hearst JE.

J Bacteriol. 1993 Oct;175(19):6299-313.

34.

Polymer models for interphase chromosomes.

Hahnfeldt P, Hearst JE, Brenner DJ, Sachs RK, Hlatky LR.

Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7854-8.

35.

Early evolution of photosynthesis: clues from nitrogenase and chlorophyll iron proteins.

Burke DH, Hearst JE, Sidow A.

Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7134-8.

36.

Laser-induced protein-DNA cross-links via psoralen furanside monoadducts.

Sastry SS, Spielmann HP, Hoang QS, Phillips AM, Sancar A, Hearst JE.

Biochemistry. 1993 Jun 1;32(21):5526-38. Erratum in: Biochemistry 1994 Feb 15;33(6):1616.

PMID:
8504073
37.
38.
41.

Molecular matchmakers.

Sancar A, Hearst JE.

Science. 1993 Mar 5;259(5100):1415-20. Review.

PMID:
8451638
43.

In vitro expression and activity of lycopene cyclase and beta-carotene hydroxylase from Erwinia herbicola.

Hundle BS, O'Brien DA, Beyer P, Kleinig H, Hearst JE.

FEBS Lett. 1993 Jan 11;315(3):329-34.

44.
45.

Psoralens and their application to the study of some molecular biological processes.

Sastry SS, Spielmann HP, Hearst JE.

Adv Enzymol Relat Areas Mol Biol. 1993;66:85-148. Review. No abstract available.

PMID:
8430517
46.

Dynamics of DNA supercoiling by transcription in Escherichia coli.

Cook DN, Ma D, Pon NG, Hearst JE.

Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10603-7.

47.

Functional expression of zeaxanthin glucosyltransferase from Erwinia herbicola and a proposed uridine diphosphate binding site.

Hundle BS, O'Brien DA, Alberti M, Beyer P, Hearst JE.

Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9321-5.

48.
49.

The crtE gene in Erwinia herbicola encodes geranylgeranyl diphosphate synthase.

Math SK, Hearst JE, Poulter CD.

Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):6761-4.

50.

Recent advances in the synthesis and structure determination of site specifically psoralen-modified DNA oligonucleotides.

Sastry SS, Spielmann HP, Dwyer TJ, Wemmer DE, Hearst JE.

J Photochem Photobiol B. 1992 Jun 30;14(1-2):65-79.

PMID:
1432385

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