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Items: 1 to 50 of 266

1.

Inhibition of Human Tyrosinase Requires Molecular Motifs Distinctively Different from Mushroom Tyrosinase.

Mann T, Gerwat W, Batzer J, Eggers K, Scherner C, Wenck H, Stäb F, Hearing VJ, Röhm KH, Kolbe L.

J Invest Dermatol. 2018 Jul;138(7):1601-1608. doi: 10.1016/j.jid.2018.01.019. Epub 2018 Feb 7.

2.

The Evaluation of Noninvasive Measurements of Erythema as a Potential Surrogate for DNA Damage in Repetitively UV-exposed Human Skin.

Miller SA, Coelho SG, Yamaguchi Y, Hearing VJ, Beer JZ, de Gruijl F.

Photochem Photobiol. 2017 Oct;93(5):1282-1288. doi: 10.1111/php.12772. Epub 2017 Jun 9.

PMID:
28380699
3.

Molecular and histological characterization of age spots.

Choi W, Yin L, Smuda C, Batzer J, Hearing VJ, Kolbe L.

Exp Dermatol. 2017 Mar;26(3):242-248. doi: 10.1111/exd.13203. Epub 2017 Feb 9.

4.

Identification of Genes Expressed in Hyperpigmented Skin Using Meta-Analysis of Microarray Data Sets.

Yin L, Coelho SG, Valencia JC, Ebsen D, Mahns A, Smuda C, Miller SA, Beer JZ, Kolbe L, Hearing VJ.

J Invest Dermatol. 2015 Oct;135(10):2455-2463. doi: 10.1038/jid.2015.179. Epub 2015 Jun 7.

5.

NUAK2 Amplification Coupled with PTEN Deficiency Promotes Melanoma Development via CDK Activation.

Namiki T, Yaguchi T, Nakamura K, Valencia JC, Coelho SG, Yin L, Kawaguchi M, Vieira WD, Kaneko Y, Tanemura A, Katayama I, Yokozeki H, Kawakami Y, Hearing VJ.

Cancer Res. 2015 Jul 1;75(13):2708-15. doi: 10.1158/0008-5472.CAN-13-3209. Epub 2015 Apr 1.

6.

Oculocutaneous albinism: developing novel antibodies targeting the proteins associated with OCA2 and OCA4.

Kondo T, Namiki T, Coelho SG, Valencia JC, Hearing VJ.

J Dermatol Sci. 2015 Jan;77(1):21-7. doi: 10.1016/j.jdermsci.2014.11.006. Epub 2014 Nov 20.

PMID:
25530116
7.

UV exposure modulates hemidesmosome plasticity, contributing to long-term pigmentation in human skin.

Coelho SG, Valencia JC, Yin L, Smuda C, Mahns A, Kolbe L, Miller SA, Beer JZ, Zhang G, Tuma PL, Hearing VJ.

J Pathol. 2015 May;236(1):17-29. doi: 10.1002/path.4497. Epub 2015 Feb 17.

8.

Photobiological implications of melanin photoprotection after UVB-induced tanning of human skin but not UVA-induced tanning.

Coelho SG, Yin L, Smuda C, Mahns A, Kolbe L, Hearing VJ.

Pigment Cell Melanoma Res. 2015 Mar;28(2):210-6. doi: 10.1111/pcmr.12331. Epub 2015 Jan 5.

9.

Antibody αPEP13h reacts with lymphangioleiomyomatosis cells in lung nodules.

Valencia JC, Steagall WK, Zhang Y, Fetsch P, Abati A, Tsukada K, Billings E, Hearing VJ, Yu ZX, Pacheco-Rodriguez G, Moss J.

Chest. 2015 Mar;147(3):771-777. doi: 10.1378/chest.14-0380.

10.

Epidermal gene expression and ethnic pigmentation variations among individuals of Asian, European and African ancestry.

Yin L, Coelho SG, Ebsen D, Smuda C, Mahns A, Miller SA, Beer JZ, Kolbe L, Hearing VJ.

Exp Dermatol. 2014 Oct;23(10):731-5. doi: 10.1111/exd.12518.

PMID:
25055985
11.

Melanocytes and their diseases.

Yamaguchi Y, Hearing VJ.

Cold Spring Harb Perspect Med. 2014 May 1;4(5). pii: a017046. doi: 10.1101/cshperspect.a017046. Review.

12.

Essential role of the molecular chaperone gp96 in regulating melanogenesis.

Zhang Y, Helke KL, Coelho SG, Valencia JC, Hearing VJ, Sun S, Liu B, Li Z.

Pigment Cell Melanoma Res. 2014 Jan;27(1):82-9. doi: 10.1111/pcmr.12165. Epub 2013 Oct 9.

13.

Non-invasive diffuse reflectance measurements of cutaneous melanin content can predict human sensitivity to ultraviolet radiation.

Coelho SG, Zmudzka BZ, Yin L, Miller SA, Yamaguchi Y, Tadokoro T, Hearing VJ, Beer JZ.

Exp Dermatol. 2013 Apr;22(4):266-71. doi: 10.1111/exd.12116.

14.

Evidence for a new paradigm for ultraviolet exposure: a universal schedule that is skin phototype independent.

Miller SA, Coelho SG, Miller SW, Yamaguchi Y, Hearing VJ, Beer JZ.

Photodermatol Photoimmunol Photomed. 2012 Aug;28(4):187-95. doi: 10.1111/j.1600-0781.2012.00666.x.

15.

Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes.

Kawaguchi M, Valencia JC, Namiki T, Suzuki T, Hearing VJ.

J Invest Dermatol. 2012 Dec;132(12):2791-9. doi: 10.1038/jid.2012.261. Epub 2012 Aug 16.

16.

Effects of cosmetic formulations containing hydroxyacids on sun-exposed skin: current applications and future developments.

Kornhauser A, Coelho SG, Hearing VJ.

Dermatol Res Pract. 2012;2012:710893. doi: 10.1155/2012/710893. Epub 2012 May 20.

17.

Characterization of the bioactive motif of neuregulin-1, a fibroblast-derived paracrine factor that regulates the constitutive color and the function of melanocytes in human skin.

Choi W, Kolbe L, Hearing VJ.

Pigment Cell Melanoma Res. 2012 Jul;25(4):477-81. doi: 10.1111/j.1755-148X.2012.01002.x. Epub 2012 Apr 27.

PMID:
22494484
18.

Determination of melanin synthetic pathways.

Hearing VJ.

J Invest Dermatol. 2011 Nov 17;131(E1):E8-E11. doi: 10.1038/skinbio.2011.4. Review. No abstract available.

19.

Milestones in melanocytes/melanogenesis.

Hearing VJ.

J Invest Dermatol. 2011 Nov 17;131(E1):E1. doi: 10.1038/skinbio.2011.1. No abstract available.

20.

NUAK2: an emerging acral melanoma oncogene.

Namiki T, Coelho SG, Hearing VJ.

Oncotarget. 2011 Sep;2(9):695-704. Review.

21.

Update on the regulation of mammalian melanocyte function and skin pigmentation.

Kondo T, Hearing VJ.

Expert Rev Dermatol. 2011 Feb 1;6(1):97-108.

22.

AMP kinase-related kinase NUAK2 affects tumor growth, migration, and clinical outcome of human melanoma.

Namiki T, Tanemura A, Valencia JC, Coelho SG, Passeron T, Kawaguchi M, Vieira WD, Ishikawa M, Nishijima W, Izumo T, Kaneko Y, Katayama I, Yamaguchi Y, Yin L, Polley EC, Liu H, Kawakami Y, Eishi Y, Takahashi E, Yokozeki H, Hearing VJ.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6597-602. doi: 10.1073/pnas.1007694108. Epub 2011 Apr 1.

23.

The Roles of ADAMs Family Proteinases in Skin Diseases.

Kawaguchi M, Hearing VJ.

Enzyme Res. 2011 Mar 8;2011:482498. doi: 10.4061/2011/482498.

24.

The deceptive nature of UVA tanning versus the modest protective effects of UVB tanning on human skin.

Miyamura Y, Coelho SG, Schlenz K, Batzer J, Smuda C, Choi W, Brenner M, Passeron T, Zhang G, Kolbe L, Wolber R, Hearing VJ.

Pigment Cell Melanoma Res. 2011 Feb;24(1):136-47. doi: 10.1111/j.1755-148X.2010.00764.x. Epub 2010 Oct 6.

25.

The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin.

Choi W, Wolber R, Gerwat W, Mann T, Batzer J, Smuda C, Liu H, Kolbe L, Hearing VJ.

J Cell Sci. 2010 Sep 15;123(Pt 18):3102-11. doi: 10.1242/jcs.064774. Epub 2010 Aug 24.

26.

Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB.

Choi W, Miyamura Y, Wolber R, Smuda C, Reinhold W, Liu H, Kolbe L, Hearing VJ.

J Invest Dermatol. 2010 Jun;130(6):1685-96. doi: 10.1038/jid.2010.5. Epub 2010 Feb 11.

27.

NADPH:quinone oxidoreductase-1 as a new regulatory enzyme that increases melanin synthesis.

Yamaguchi Y, Hearing VJ, Maeda A, Morita A.

J Invest Dermatol. 2010 Mar;130(3):645-7. doi: 10.1038/jid.2009.378.

28.

Role of the ubiquitin proteasome system in regulating skin pigmentation.

Ando H, Ichihashi M, Hearing VJ.

Int J Mol Sci. 2009 Nov 20;10(10):4428-34. doi: 10.3390/ijms10104428. Review.

29.

Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.

Hoashi T, Sato S, Yamaguchi Y, Passeron T, Tamaki K, Hearing VJ.

FASEB J. 2010 May;24(5):1616-29. doi: 10.1096/fj.09-151019. Epub 2010 Jan 7.

30.

Applications of hydroxy acids: classification, mechanisms, and photoactivity.

Kornhauser A, Coelho SG, Hearing VJ.

Clin Cosmet Investig Dermatol. 2010 Nov 24;3:135-42. doi: 10.2147/CCID.S9042.

31.

UVA tanning is involved in the increased incidence of skin cancers in fair-skinned young women.

Coelho SG, Hearing VJ.

Pigment Cell Melanoma Res. 2010 Feb;23(1):57-63. doi: 10.1111/j.1755-148X.2009.00656.x. Epub 2009 Dec 2. Review.

32.

The secreted form of a melanocyte membrane-bound glycoprotein (Pmel17/gp100) is released by ectodomain shedding.

Hoashi T, Tamaki K, Hearing VJ.

FASEB J. 2010 Mar;24(3):916-30. doi: 10.1096/fj.09-140921. Epub 2009 Nov 2.

33.

Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma.

Chen KG, Valencia JC, Gillet JP, Hearing VJ, Gottesman MM.

Pigment Cell Melanoma Res. 2009 Dec;22(6):740-9. doi: 10.1111/j.1755-148X.2009.00630.x. Epub 2009 Aug 29. Review.

34.

Influence of melanosome dynamics on melanoma drug sensitivity.

Chen KG, Leapman RD, Zhang G, Lai B, Valencia JC, Cardarelli CO, Vieira WD, Hearing VJ, Gottesman MM.

J Natl Cancer Inst. 2009 Sep 16;101(18):1259-71. doi: 10.1093/jnci/djp259. Epub 2009 Aug 24.

35.

Regulation of skin pigmentation and thickness by Dickkopf 1 (DKK1).

Yamaguchi Y, Morita A, Maeda A, Hearing VJ.

J Investig Dermatol Symp Proc. 2009 Aug;14(1):73-5. doi: 10.1038/jidsymp.2009.4. Review.

36.

Short- and long-term effects of UV radiation on the pigmentation of human skin.

Coelho SG, Choi W, Brenner M, Miyamura Y, Yamaguchi Y, Wolber R, Smuda C, Batzer J, Kolbe L, Ito S, Wakamatsu K, Zmudzka BZ, Beer JZ, Miller SA, Hearing VJ.

J Investig Dermatol Symp Proc. 2009 Aug;14(1):32-5. doi: 10.1038/jidsymp.2009.10.

37.

What are melanocytes really doing all day long...?

Plonka PM, Passeron T, Brenner M, Tobin DJ, Shibahara S, Thomas A, Slominski A, Kadekaro AL, Hershkovitz D, Peters E, Nordlund JJ, Abdel-Malek Z, Takeda K, Paus R, Ortonne JP, Hearing VJ, Schallreuter KU.

Exp Dermatol. 2009 Sep;18(9):799-819. doi: 10.1111/j.1600-0625.2009.00912.x. Epub 2009 Jul 30. Review. Erratum in: Exp Dermatol. 2009 Dec;18(12):1096.

38.

Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady-state retention of mutant forms in the proximal golgi.

Sánchez-Laorden BL, Herraiz C, Valencia JC, Hearing VJ, Jiménez-Cervantes C, García-Borrón JC.

J Cell Physiol. 2009 Sep;220(3):640-54. doi: 10.1002/jcp.21804.

39.

Physiological factors that regulate skin pigmentation.

Yamaguchi Y, Hearing VJ.

Biofactors. 2009 Mar-Apr;35(2):193-9. doi: 10.1002/biof.29. Review.

40.

The effects of topically applied glycolic acid and salicylic acid on ultraviolet radiation-induced erythema, DNA damage and sunburn cell formation in human skin.

Kornhauser A, Wei RR, Yamaguchi Y, Coelho SG, Kaidbey K, Barton C, Takahashi K, Beer JZ, Miller SA, Hearing VJ.

J Dermatol Sci. 2009 Jul;55(1):10-7. doi: 10.1016/j.jdermsci.2009.03.011. Epub 2009 May 2.

41.

Standardization of in vitro macrophotography for assessment of cutaneous responses.

Coelho SG, Koo E, Hearing VJ.

Photochem Photobiol. 2009 Jul-Aug;85(4):1032-7. doi: 10.1111/j.1751-1097.2009.00549.x. Epub 2009 Mar 20.

42.

Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid.

Passeron T, Valencia JC, Namiki T, Vieira WD, Passeron H, Miyamura Y, Hearing VJ.

J Clin Invest. 2009 Apr;119(4):954-63. doi: 10.1172/JCI34015. Epub 2009 Mar 9.

43.

Long-lasting pigmentation of human skin, a new look at an overlooked response to UV.

Coelho SG, Zhou Y, Bushar HF, Miller SA, Zmudzka BZ, Hearing VJ, Beer JZ.

Pigment Cell Melanoma Res. 2009 Apr;22(2):238-41. doi: 10.1111/j.1755-148X.2009.00550.x. Epub 2009 Feb 17. No abstract available.

44.

Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r.

Le Pape E, Passeron T, Giubellino A, Valencia JC, Wolber R, Hearing VJ.

Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1802-7. doi: 10.1073/pnas.0806753106. Epub 2009 Jan 27.

45.

The expanding role and presence of neuromelanins in the human brain - why gray matter is gray.

Hearing VJ.

Pigment Cell Melanoma Res. 2009 Feb;22(1):10-1. doi: 10.1111/j.1755-148X.2008.00537.x. Epub 2008 Dec 19. No abstract available.

46.

Evidence for the ectopic synthesis of melanin in human adipose tissue.

Randhawa M, Huff T, Valencia JC, Younossi Z, Chandhoke V, Hearing VJ, Baranova A.

FASEB J. 2009 Mar;23(3):835-43. doi: 10.1096/fj.08-116327. Epub 2008 Oct 29.

47.

Long-lasting molecular changes in human skin after repetitive in situ UV irradiation.

Brenner M, Coelho SG, Beer JZ, Miller SA, Wolber R, Smuda C, Hearing VJ.

J Invest Dermatol. 2009 Apr;129(4):1002-11. doi: 10.1038/jid.2008.325. Epub 2008 Oct 23.

48.

A novel approach to enhance antibody sensitivity and specificity by peptide cross-linking.

Namiki T, Valencia JC, Hall MD, Hearing VJ.

Anal Biochem. 2008 Dec 15;383(2):265-9. doi: 10.1016/j.ab.2008.08.024. Epub 2008 Aug 30.

49.

Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor.

Le Pape E, Wakamatsu K, Ito S, Wolber R, Hearing VJ.

Pigment Cell Melanoma Res. 2008 Aug;21(4):477-86. doi: 10.1111/j.1755-148X.2008.00479.x. Epub 2008 Jun 27.

50.

Pigmentation effects of solar-simulated radiation as compared with UVA and UVB radiation.

Wolber R, Schlenz K, Wakamatsu K, Smuda C, Nakanishi Y, Hearing VJ, Ito S.

Pigment Cell Melanoma Res. 2008 Aug;21(4):487-91. doi: 10.1111/j.1755-148X.2008.00470.x. Epub 2008 Jun 20.

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