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Items: 1 to 50 of 159

1.

[France, a refuge for researchers in danger].

Prochiantz A, Heard E.

Med Sci (Paris). 2018 Aug-Sep;34(8-9):635-636. doi: 10.1051/medsci/20183408001. Epub 2018 Sep 19. French. No abstract available.

PMID:
30230469
2.

Live Imaging of Xist RNA.

Masui O, Heard E, Koseki H.

Methods Mol Biol. 2018;1861:67-72. doi: 10.1007/978-1-4939-8766-5_6.

PMID:
30218360
3.

Effective normalization for copy number variation in Hi-C data.

Servant N, Varoquaux N, Heard E, Barillot E, Vert JP.

BMC Bioinformatics. 2018 Sep 6;19(1):313. doi: 10.1186/s12859-018-2256-5.

4.

Exploring Intimate Partner Violence in Polynesia: A Scoping Review.

Heard E, Fitzgerald L, Whittaker M, Va'ai S, Mutch A.

Trauma Violence Abuse. 2018 Aug 20:1524838018795504. doi: 10.1177/1524838018795504. [Epub ahead of print]

PMID:
30126350
5.

Suiga/Change: An Ethnodrama Exploring Challenges in Intimate Relationships With Young People in Samoa.

Heard E, Fitzgerald L, Va'ai S, Collins F, Mutch A.

Violence Against Women. 2018 Jun 1:1077801218778388. doi: 10.1177/1077801218778388. [Epub ahead of print]

PMID:
29961399
6.

Transcriptome Profiling of Single Mouse Oocytes.

Borensztein M, Syx L, Servant N, Heard E.

Methods Mol Biol. 2018;1818:51-65. doi: 10.1007/978-1-4939-8603-3_7.

PMID:
29961255
7.

The Ftx Noncoding Locus Controls X Chromosome Inactivation Independently of Its RNA Products.

Furlan G, Gutierrez Hernandez N, Huret C, Galupa R, van Bemmel JG, Romito A, Heard E, Morey C, Rougeulle C.

Mol Cell. 2018 May 3;70(3):462-472.e8. doi: 10.1016/j.molcel.2018.03.024.

PMID:
29706539
8.

Topologically Associating Domains in Chromosome Architecture and Gene Regulatory Landscapes during Development, Disease, and Evolution.

Galupa R, Heard E.

Cold Spring Harb Symp Quant Biol. 2017;82:267-278. doi: 10.1101/sqb.2017.82.035030. Epub 2018 Apr 23.

PMID:
29686034
9.

Using Applied Theater in Primary, Secondary, and Tertiary Prevention of Intimate Partner Violence: A Systematic Review.

Heard E, Mutch A, Fitzgerald L.

Trauma Violence Abuse. 2017 Jan 1:1524838017750157. doi: 10.1177/1524838017750157. [Epub ahead of print]

PMID:
29334014
10.

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass.

Borensztein M, Okamoto I, Syx L, Guilbaud G, Picard C, Ancelin K, Galupa R, Diabangouaya P, Servant N, Barillot E, Surani A, Saitou M, Chen CJ, Anastassiadis K, Heard E.

Nat Commun. 2017 Nov 3;8(1):1297. doi: 10.1038/s41467-017-01415-5.

11.

Genetic and epigenetic features direct differential efficiency of Xist-mediated silencing at X-chromosomal and autosomal locations.

Loda A, Brandsma JH, Vassilev I, Servant N, Loos F, Amirnasr A, Splinter E, Barillot E, Poot RA, Heard E, Gribnau J.

Nat Commun. 2017 Sep 25;8(1):690. doi: 10.1038/s41467-017-00528-1.

12.

Preface.

Heard E, Brockdorff N.

Philos Trans R Soc Lond B Biol Sci. 2017 Nov 5;372(1733). pii: 20160353. doi: 10.1098/rstb.2016.0353. No abstract available.

13.

Corrigendum: Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.

Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY.

Nat Genet. 2017 May 26;49(6):970. doi: 10.1038/ng0617-970a. No abstract available.

PMID:
28546577
14.

RNA FISH to Study Zygotic Genome Activation in Early Mouse Embryos.

Ranisavljevic N, Okamoto I, Heard E, Ancelin K.

Methods Mol Biol. 2017;1605:133-145. doi: 10.1007/978-1-4939-6988-3_9.

PMID:
28456962
15.

X chromosome inactivation: new players in the initiation of gene silencing.

Pinheiro I, Heard E.

F1000Res. 2017 Mar 27;6. pii: F1000 Faculty Rev-344. doi: 10.12688/f1000research.10707.1. eCollection 2017. Review.

16.

Novel players in X inactivation: insights into Xist-mediated gene silencing and chromosome conformation.

da Rocha ST, Heard E.

Nat Struct Mol Biol. 2017 Mar 3;24(3):197-204. doi: 10.1038/nsmb.3370. Review.

PMID:
28257137
17.

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure.

Borensztein M, Syx L, Ancelin K, Diabangouaya P, Picard C, Liu T, Liang JB, Vassilev I, Galupa R, Servant N, Barillot E, Surani A, Chen CJ, Heard E.

Nat Struct Mol Biol. 2017 Mar;24(3):226-233. doi: 10.1038/nsmb.3365. Epub 2017 Jan 30.

18.

Landscape of monoallelic DNA accessibility in mouse embryonic stem cells and neural progenitor cells.

Xu J, Carter AC, Gendrel AV, Attia M, Loftus J, Greenleaf WJ, Tibshirani R, Heard E, Chang HY.

Nat Genet. 2017 Mar;49(3):377-386. doi: 10.1038/ng.3769. Epub 2017 Jan 23. Erratum in: Nat Genet. 2017 May 26;49(6):970.

19.

XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development.

Vallot C, Patrat C, Collier AJ, Huret C, Casanova M, Liyakat Ali TM, Tosolini M, Frydman N, Heard E, Rugg-Gunn PJ, Rougeulle C.

Cell Stem Cell. 2017 Jan 5;20(1):102-111. doi: 10.1016/j.stem.2016.10.014. Epub 2016 Dec 15.

20.

Efficient and versatile CRISPR engineering of human neurons in culture to model neurological disorders.

Shah RR, Cholewa-Waclaw J, Davies FCJ, Paton KM, Chaligne R, Heard E, Abbott CM, Bird AP.

Wellcome Open Res. 2016 Nov 15;1:13. doi: 10.12688/wellcomeopenres.10011.1.

21.

Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.

Cooper S, Grijzenhout A, Underwood E, Ancelin K, Zhang T, Nesterova TB, Anil-Kirmizitas B, Bassett A, Kooistra SM, Agger K, Helin K, Heard E, Brockdorff N.

Nat Commun. 2016 Nov 28;7:13661. doi: 10.1038/ncomms13661.

22.

3D solutions to complex gene regulation.

Heard E.

Nat Rev Mol Cell Biol. 2016 Nov 21;17(12):739. doi: 10.1038/nrm.2016.154. No abstract available.

PMID:
27869155
23.

Closing the loop: 3C versus DNA FISH.

Giorgetti L, Heard E.

Genome Biol. 2016 Oct 19;17(1):215. Review.

25.

Genomes of Ellobius species provide insight into the evolutionary dynamics of mammalian sex chromosomes.

Mulugeta E, Wassenaar E, Sleddens-Linkels E, van IJcken WF, Heard E, Grootegoed JA, Just W, Gribnau J, Baarends WM.

Genome Res. 2016 Sep;26(9):1202-10. doi: 10.1101/gr.201665.115. Epub 2016 Aug 10.

26.

Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming.

Cantone I, Bagci H, Dormann D, Dharmalingam G, Nesterova T, Brockdorff N, Rougeulle C, Vallot C, Heard E, Chaligne R, Merkenschlager M, Fisher AG.

Nat Commun. 2016 Aug 10;7:12354. doi: 10.1038/ncomms12354.

27.

LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation.

Chow JC, Ciaudo C, Fazzari MJ, Mise N, Servant N, Glass JL, Attreed M, Avner P, Wutz A, Barillot E, Greally JM, Voinnet O, Heard E.

Cell. 2016 Jul 28;166(3):782. doi: 10.1016/j.cell.2016.07.013. No abstract available.

28.

Structural organization of the inactive X chromosome in the mouse.

Giorgetti L, Lajoie BR, Carter AC, Attia M, Zhan Y, Xu J, Chen CJ, Kaplan N, Chang HY, Heard E, Dekker J.

Nature. 2016 Jul 28;535(7613):575-9. Epub 2016 Jul 18.

29.

Random monoallelic expression of genes on autosomes: Parallels with X-chromosome inactivation.

Gendrel AV, Marion-Poll L, Katoh K, Heard E.

Semin Cell Dev Biol. 2016 Aug;56:100-110. doi: 10.1016/j.semcdb.2016.04.007. Epub 2016 Apr 19. Review.

PMID:
27101886
30.

Structural Fluctuations of the Chromatin Fiber within Topologically Associating Domains.

Tiana G, Amitai A, Pollex T, Piolot T, Holcman D, Heard E, Giorgetti L.

Biophys J. 2016 Mar 29;110(6):1234-45. doi: 10.1016/j.bpj.2016.02.003.

31.

Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation.

Ancelin K, Syx L, Borensztein M, Ranisavljevic N, Vassilev I, Briseño-Roa L, Liu T, Metzger E, Servant N, Barillot E, Chen CJ, Schüle R, Heard E.

Elife. 2016 Feb 2;5. pii: e08851. doi: 10.7554/eLife.08851.

32.

Culture X: addressing barriers to physical activity in Samoa.

Heard EM, Auvaa L, Conway BA.

Health Promot Int. 2017 Aug 1;32(4):734-742. doi: 10.1093/heapro/dav119.

PMID:
26825998
33.

HiC-Pro: an optimized and flexible pipeline for Hi-C data processing.

Servant N, Varoquaux N, Lajoie BR, Viara E, Chen CJ, Vert JP, Heard E, Dekker J, Barillot E.

Genome Biol. 2015 Dec 1;16:259. doi: 10.1186/s13059-015-0831-x.

34.

Structural and functional diversity of Topologically Associating Domains.

Dekker J, Heard E.

FEBS Lett. 2015 Oct 7;589(20 Pt A):2877-84. doi: 10.1016/j.febslet.2015.08.044. Epub 2015 Sep 5. Review.

35.

[The legacy of Mary F. Lyon (1925-2014)].

Guénet JL, Panthier JJ, Avner P, Heard E, Montagutelli X.

Med Sci (Paris). 2015 Jun-Jul;31(6-7):687-9. doi: 10.1051/medsci/20153106024. Epub 2015 Jul 7. French. No abstract available.

36.

X-chromosome inactivation: new insights into cis and trans regulation.

Galupa R, Heard E.

Curr Opin Genet Dev. 2015 Apr;31:57-66. doi: 10.1016/j.gde.2015.04.002. Epub 2015 May 22. Review.

PMID:
26004255
37.

Correction: RNAi-Dependent and Independent Control of LINE1 Accumulation and Mobility in Mouse Embryonic Stem Cells.

Ciaudo C, Jay F, Okamoto I, Chen CJ, Sarazin A, Servant N, Barillot E, Heard E, Voinnet O.

PLoS Genet. 2015 May 14;11(5):e1005247. doi: 10.1371/journal.pgen.1005247. eCollection 2015 May. No abstract available.

38.

Systematic discovery of Xist RNA binding proteins.

Chu C, Zhang QC, da Rocha ST, Flynn RA, Bharadwaj M, Calabrese JM, Magnuson T, Heard E, Chang HY.

Cell. 2015 Apr 9;161(2):404-16. doi: 10.1016/j.cell.2015.03.025. Epub 2015 Apr 2.

39.

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer.

Chaligné R, Popova T, Mendoza-Parra MA, Saleem MA, Gentien D, Ban K, Piolot T, Leroy O, Mariani O, Gronemeyer H, Vincent-Salomon A, Stern MH, Heard E.

Genome Res. 2015 Apr;25(4):488-503. doi: 10.1101/gr.185926.114. Epub 2015 Feb 4.

40.

Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation.

Sanulli S, Justin N, Teissandier A, Ancelin K, Portoso M, Caron M, Michaud A, Lombard B, da Rocha ST, Offer J, Loew D, Servant N, Wassef M, Burlina F, Gamblin SJ, Heard E, Margueron R.

Mol Cell. 2015 Mar 5;57(5):769-783. doi: 10.1016/j.molcel.2014.12.020. Epub 2015 Jan 22.

41.

High-resolution 3D DNA FISH using plasmid probes and computational correction of optical aberrations to study chromatin structure at the sub-megabase scale.

Giorgetti L, Piolot T, Heard E.

Methods Mol Biol. 2015;1262:37-53. doi: 10.1007/978-1-4939-2253-6_3.

PMID:
25555574
42.

Love Bugs: promoting sexual health among young people in Samoa.

Heard E, Auvaa L, Pickering C.

Health Promot J Austr. 2015 Apr;26(1):30-32. doi: 10.1071/HE14055.

PMID:
25436987
43.

Noncoding RNAs and epigenetic mechanisms during X-chromosome inactivation.

Gendrel AV, Heard E.

Annu Rev Cell Dev Biol. 2014;30:561-80. doi: 10.1146/annurev-cellbio-101512-122415. Epub 2014 Jun 27. Review.

PMID:
25000994
44.

X-chromosome inactivation in development and cancer.

Chaligné R, Heard E.

FEBS Lett. 2014 Aug 1;588(15):2514-22. doi: 10.1016/j.febslet.2014.06.023. Epub 2014 Jun 14. Review.

45.

MOF-associated complexes ensure stem cell identity and Xist repression.

Chelmicki T, Dündar F, Turley MJ, Khanam T, Aktas T, Ramírez F, Gendrel AV, Wright PR, Videm P, Backofen R, Heard E, Manke T, Akhtar A.

Elife. 2014 May 19;3:e02024. doi: 10.7554/eLife.02024.

46.

Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription.

Giorgetti L, Galupa R, Nora EP, Piolot T, Lam F, Dekker J, Tiana G, Heard E.

Cell. 2014 May 8;157(4):950-63. doi: 10.1016/j.cell.2014.03.025.

47.

Transgenerational epigenetic inheritance: myths and mechanisms.

Heard E, Martienssen RA.

Cell. 2014 Mar 27;157(1):95-109. doi: 10.1016/j.cell.2014.02.045. Review.

48.

Developmental dynamics and disease potential of random monoallelic gene expression.

Gendrel AV, Attia M, Chen CJ, Diabangouaya P, Servant N, Barillot E, Heard E.

Dev Cell. 2014 Feb 24;28(4):366-80. doi: 10.1016/j.devcel.2014.01.016.

49.

The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network.

Schulz EG, Meisig J, Nakamura T, Okamoto I, Sieber A, Picard C, Borensztein M, Saitou M, Blüthgen N, Heard E.

Cell Stem Cell. 2014 Feb 6;14(2):203-16. doi: 10.1016/j.stem.2013.11.022.

50.

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome.

da Rocha ST, Boeva V, Escamilla-Del-Arenal M, Ancelin K, Granier C, Matias NR, Sanulli S, Chow J, Schulz E, Picard C, Kaneko S, Helin K, Reinberg D, Stewart AF, Wutz A, Margueron R, Heard E.

Mol Cell. 2014 Jan 23;53(2):301-16. doi: 10.1016/j.molcel.2014.01.002.

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