Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 137

1.

Metformin Hydrochloride and Sitagliptin Phosphate Fixed-Dose Combination Product Prepared Using Melt Granulation Continuous Processing Technology.

Kelleher JF, Madi AM, Gilvary GC, Tian YW, Li S, Almajaan A, Loys ZS, Jones DS, Andrews GP, Healy AM.

AAPS PharmSciTech. 2019 Dec 12;21(1):23. doi: 10.1208/s12249-019-1553-2.

PMID:
31832799
2.

The use of hydrophobic amino acids in protecting spray dried trehalose formulations against moisture-induced changes.

Mah PT, O'Connell P, Focaroli S, Lundy R, O'Mahony TF, Hastedt JE, Gitlin I, Oscarson S, Fahy JV, Healy AM.

Eur J Pharm Biopharm. 2019 Nov;144:139-153. doi: 10.1016/j.ejpb.2019.09.014. Epub 2019 Sep 16.

PMID:
31536784
3.

High Prevalence of Diabetes Distress in a University Population.

Beverly EA, Rennie RG, Guseman EH, Rodgers A, Healy AM.

J Am Osteopath Assoc. 2019 Sep 1;119(9):556-568. doi: 10.7556/jaoa.2019.099.

PMID:
31449302
4.

Designing Fast-Dissolving Orodispersible Films of Amphotericin B for Oropharyngeal Candidiasis.

Serrano DR, Fernandez-Garcia R, Mele M, Healy AM, Lalatsa A.

Pharmaceutics. 2019 Aug 1;11(8). pii: E369. doi: 10.3390/pharmaceutics11080369.

5.

Nanoparticle Tracking Analysis to Examine the Temperature-Induced Aggregation of Proteins.

Sladek S, McComiskey K, Healy AM, Tajber L.

Methods Mol Biol. 2019;2039:131-139. doi: 10.1007/978-1-4939-9678-0_10.

PMID:
31342424
6.

Amorphous solid dispersions of ketoprofen and poly-vinyl polymers prepared via electrospraying and spray drying: A comparison of particle characteristics and performance.

Browne E, Charifou R, Worku ZA, Babu RP, Healy AM.

Int J Pharm. 2019 Jul 20;566:173-184. doi: 10.1016/j.ijpharm.2019.05.062. Epub 2019 May 24.

PMID:
31132449
7.

The development of an inline Raman spectroscopic analysis method as a quality control tool for hot melt extruded ramipril fixed-dose combination products.

Andrews GP, Jones DS, Senta-Loys Z, Almajaan A, Li S, Chevallier O, Elliot C, Healy AM, Kelleher JF, Madi AM, Gilvary GC, Tian Y.

Int J Pharm. 2019 Jul 20;566:476-487. doi: 10.1016/j.ijpharm.2019.05.029. Epub 2019 May 11.

PMID:
31085253
8.

Predicting the critical quality attributes of ibuprofen tablets via modelling of process parameters for roller compaction and tabletting.

Matji A, Donato N, Gagol A, Morales E, Carvajal L, Serrano DR, Worku ZA, Healy AM, Torrado JJ.

Int J Pharm. 2019 Jun 30;565:209-218. doi: 10.1016/j.ijpharm.2019.05.011. Epub 2019 May 7.

PMID:
31075438
9.

HNF1β Diabetes or Maturity-Onset Diabetes of the Young Type 5 With Rare HNF1β Mutation: A Case Report.

Haynes AL, Healy AM.

Clin Diabetes. 2019 Apr;37(2):180-182. doi: 10.2337/cd18-0033. No abstract available.

PMID:
31057226
10.

A Design of Experiment (DoE) approach to optimise spray drying process conditions for the production of trehalose/leucine formulations with application in pulmonary delivery.

Focaroli S, Mah PT, Hastedt JE, Gitlin I, Oscarson S, Fahy JV, Healy AM.

Int J Pharm. 2019 May 1;562:228-240. doi: 10.1016/j.ijpharm.2019.03.004. Epub 2019 Mar 5.

PMID:
30849470
11.

In Situ Cocrystallization of Dapsone and Caffeine during Fluidized Bed Granulation Processing.

Todaro V, Worku ZA, Cabral LM, Healy AM.

AAPS PharmSciTech. 2019 Jan 2;20(1):28. doi: 10.1208/s12249-018-1228-4.

PMID:
30603811
12.

Engineering of pharmaceutical cocrystals in an excipient matrix: Spray drying versus hot melt extrusion.

Walsh D, Serrano DR, Worku ZA, Madi AM, O'Connell P, Twamley B, Healy AM.

Int J Pharm. 2018 Nov 15;551(1-2):241-256. doi: 10.1016/j.ijpharm.2018.09.029. Epub 2018 Sep 14.

PMID:
30223079
13.

Development of a new formulation of roflumilast for pulmonary drug delivery to treat inflammatory lung conditions.

Suzuki ÉY, Amaro MI, de Almeida GS, Cabral LM, Healy AM, de Sousa VP.

Int J Pharm. 2018 Oct 25;550(1-2):89-99. doi: 10.1016/j.ijpharm.2018.08.035. Epub 2018 Aug 18.

PMID:
30130605
14.

Diabetes Fellowship in Primary Care: A Survey of Graduates.

Healy AM, Tanenberg RJ, Schwartz FL, Shubrook JH.

J Am Osteopath Assoc. 2018 Aug 1;118(8):538-543. doi: 10.7556/jaoa.2018.122.

PMID:
30073337
15.

Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods.

do Amaral LH, do Carmo FA, Amaro MI, de Sousa VP, da Silva LCRP, de Almeida GS, Rodrigues CR, Healy AM, Cabral LM.

AAPS PharmSciTech. 2018 Aug;19(6):2687-2699. doi: 10.1208/s12249-018-1101-5. Epub 2018 Jul 2.

PMID:
29968042
16.

Maximising success in multidrug formulation development: A review.

Kavanagh ON, Albadarin AB, Croker DM, Healy AM, Walker GM.

J Control Release. 2018 Aug 10;283:1-19. doi: 10.1016/j.jconrel.2018.05.024. Epub 2018 May 23. Review.

PMID:
29802867
17.

A comparative study between hot-melt extrusion and spray-drying for the manufacture of anti-hypertension compatible monolithic fixed-dose combination products.

Kelleher JF, Gilvary GC, Madi AM, Jones DS, Li S, Tian Y, Almajaan A, Senta-Loys Z, Andrews GP, Healy AM.

Int J Pharm. 2018 Jul 10;545(1-2):183-196. doi: 10.1016/j.ijpharm.2018.05.008. Epub 2018 May 3.

PMID:
29730176
18.

Endocrinologists' Opinions of Diabetology as a Primary Care Subspecialty.

Healy AM, Shubrook JH, Schwartz FL, Cummings DM, Drake AJ 3rd, Tanenberg RJ.

Clin Diabetes. 2018 Apr;36(2):168-173. doi: 10.2337/cd17-0097.

19.

Neighborhood Disadvantage and Body Mass Index: A Study of Residential Relocation.

Rachele JN, Kavanagh AM, Brown WJ, Healy AM, Turrell G.

Am J Epidemiol. 2018 Aug 1;187(8):1696-1703. doi: 10.1093/aje/kwx390.

PMID:
29351569
20.

Novel Iron-Whey Protein Microspheres Protect Gut Epithelial Cells from Iron-Related Oxidative Stress and Damage and Improve Iron Absorption in Fasting Adults.

Wang J, Radics G, Whelehan M, OʼDriscoll A, Healy AM, Gilmer JF, Ledwidge M.

Acta Haematol. 2017;138(4):223-232. doi: 10.1159/000480632. Epub 2018 Jan 5.

PMID:
29301124
21.

New aerosol formulation to control ciprofloxacin pulmonary concentration.

Lamy B, Tewes F, Serrano DR, Lamarche I, Gobin P, Couet W, Healy AM, Marchand S.

J Control Release. 2018 Feb 10;271:118-126. doi: 10.1016/j.jconrel.2017.12.021. Epub 2017 Dec 22.

PMID:
29277683
22.

Production of cocrystals in an excipient matrix by spray drying.

Walsh D, Serrano DR, Worku ZA, Norris BA, Healy AM.

Int J Pharm. 2018 Jan 30;536(1):467-477. doi: 10.1016/j.ijpharm.2017.12.020. Epub 2017 Dec 11.

PMID:
29241701
23.

Optimising the in vitro and in vivo performance of oral cocrystal formulations via spray coating.

Serrano DR, Walsh D, O'Connell P, Mugheirbi NA, Worku ZA, Bolas-Fernandez F, Galiana C, Dea-Ayuela MA, Healy AM.

Eur J Pharm Biopharm. 2018 Mar;124:13-27. doi: 10.1016/j.ejpb.2017.11.015. Epub 2017 Dec 22.

PMID:
29196273
24.

Neighborhood socioeconomic disadvantage and body mass index among residentially stable mid-older aged adults: Findings from the HABITAT multilevel longitudinal study.

Rachele JN, Kavanagh A, Brown WJ, Healy AM, Schmid CJ, Turrell G.

Prev Med. 2017 Dec;105:271-274. doi: 10.1016/j.ypmed.2017.09.017. Epub 2017 Sep 27.

PMID:
28963008
25.

The Time Is Now: Diabetes Fellowships in the United States.

Sadhu AR, Healy AM, Patil SP, Cummings DM, Shubrook JH, Tanenberg RJ.

Curr Diab Rep. 2017 Sep 23;17(11):108. doi: 10.1007/s11892-017-0936-6. Review.

PMID:
28942533
26.

A Comparative Study on the Performance of Inert and Functionalized Spheres Coated with Solid Dispersions Made of Two Structurally Related Antifungal Drugs.

Mugheirbi NA, O'Connell P, Serrano DR, Healy AM, Taylor LS, Tajber L.

Mol Pharm. 2017 Nov 6;14(11):3718-3728. doi: 10.1021/acs.molpharmaceut.7b00482. Epub 2017 Sep 29.

PMID:
28922604
27.

Modelling and understanding powder flow properties and compactability of selected active pharmaceutical ingredients, excipients and physical mixtures from critical material properties.

Worku ZA, Kumar D, Gomes JV, He Y, Glennon B, Ramisetty KA, Rasmuson ÅC, O'Connell P, Gallagher KH, Woods T, Shastri NR, Healy AM.

Int J Pharm. 2017 Oct 5;531(1):191-204. doi: 10.1016/j.ijpharm.2017.08.063. Epub 2017 Aug 9.

PMID:
28801109
28.

Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals.

Healy AM, Worku ZA, Kumar D, Madi AM.

Adv Drug Deliv Rev. 2017 Aug 1;117:25-46. doi: 10.1016/j.addr.2017.03.002. Epub 2017 Mar 22. Review.

PMID:
28342786
29.

Development of a Discriminative In Vitro Release Test for Rivastigmine Transdermal Patches Using Pharmacopeial Apparatuses: USP 5 and USP 6.

Simon A, Amaro MI, Healy AM, Cabral LM, de Sousa VP.

AAPS PharmSciTech. 2017 Oct;18(7):2561-2569. doi: 10.1208/s12249-017-0738-9. Epub 2017 Feb 21.

PMID:
28224389
30.

Engineering Oral and Parenteral Amorphous Amphotericin B Formulations against Experimental Trypanosoma cruzi Infections.

Rolón M, Serrano DR, Lalatsa A, de Pablo E, Torrado JJ, Ballesteros MP, Healy AM, Vega C, Coronel C, Bolás-Fernández F, Dea-Ayuela MA.

Mol Pharm. 2017 Apr 3;14(4):1095-1106. doi: 10.1021/acs.molpharmaceut.6b01034. Epub 2017 Mar 3.

PMID:
28198632
31.

Materials and methods for delivery of biological drugs.

Zelikin AN, Ehrhardt C, Healy AM.

Nat Chem. 2016 Oct 21;8(11):997-1007. doi: 10.1038/nchem.2629. Review.

PMID:
27768097
32.

Comparative evaluation of rivastigmine permeation from a transdermal system in the Franz cell using synthetic membranes and pig ear skin with in vivo-in vitro correlation.

Simon A, Amaro MI, Healy AM, Cabral LM, de Sousa VP.

Int J Pharm. 2016 Oct 15;512(1):234-241. doi: 10.1016/j.ijpharm.2016.08.052. Epub 2016 Aug 26.

33.

Modelling and shadowgraph imaging of cocrystal dissolution and assessment of in vitro antimicrobial activity for sulfadimidine/4-aminosalicylic acid cocrystals.

Serrano DR, Persoons T, D'Arcy DM, Galiana C, Dea-Ayuela MA, Healy AM.

Eur J Pharm Sci. 2016 Jun 30;89:125-36. doi: 10.1016/j.ejps.2016.04.030. Epub 2016 Apr 27.

PMID:
27131605
34.

Development of a novel dry powder inhalation formulation for the delivery of rivastigmine hydrogen tartrate.

Simon A, Amaro MI, Cabral LM, Healy AM, de Sousa VP.

Int J Pharm. 2016 Mar 30;501(1-2):124-38. doi: 10.1016/j.ijpharm.2016.01.066. Epub 2016 Feb 1.

35.

Amorphous Calcium Carbonate Based-Microparticles for Peptide Pulmonary Delivery.

Tewes F, Gobbo OL, Ehrhardt C, Healy AM.

ACS Appl Mater Interfaces. 2016 Jan 20;8(2):1164-75. doi: 10.1021/acsami.5b09023. Epub 2016 Jan 5.

36.

Ciprofloxacin-Loaded Inorganic-Organic Composite Microparticles To Treat Bacterial Lung Infection.

Tewes F, Brillault J, Lamy B, O'Connell P, Olivier JC, Couet W, Healy AM.

Mol Pharm. 2016 Jan 4;13(1):100-12. doi: 10.1021/acs.molpharmaceut.5b00543. Epub 2015 Dec 19.

37.

Mitigating unwanted amorphisation: A screening method for the selection of suitable excipients.

Amharar Y, Curtin V, Gallagher KH, O'Siochru E, O'Connell P, Healy AM.

Eur J Pharm Sci. 2016 Jan 1;81:181-8. doi: 10.1016/j.ejps.2015.10.016. Epub 2015 Oct 19.

PMID:
26493586
38.

Cocrystal habit engineering to improve drug dissolution and alter derived powder properties.

Serrano DR, O'Connell P, Paluch KJ, Walsh D, Healy AM.

J Pharm Pharmacol. 2016 May;68(5):665-77. doi: 10.1111/jphp.12476. Epub 2015 Sep 26.

PMID:
26408342
39.

Comparative Study of Different Methods for the Prediction of Drug-Polymer Solubility.

Knopp MM, Tajber L, Tian Y, Olesen NE, Jones DS, Kozyra A, Löbmann K, Paluch K, Brennan CM, Holm R, Healy AM, Andrews GP, Rades T.

Mol Pharm. 2015 Sep 8;12(9):3408-19. doi: 10.1021/acs.molpharmaceut.5b00423. Epub 2015 Aug 11.

PMID:
26214347
40.

Emerging Nanonisation Technologies: Tailoring Crystalline Versus Amorphous Nanomaterials.

Serrano DR, Gallagher KH, Healy AM.

Curr Top Med Chem. 2015;15(22):2327-40. Review.

PMID:
26043733
41.

Self-assembled carrageenan/protamine polyelectrolyte nanoplexes-Investigation of critical parameters governing their formation and characteristics.

Dul M, Paluch KJ, Kelly H, Healy AM, Sasse A, Tajber L.

Carbohydr Polym. 2015 Jun 5;123:339-49. doi: 10.1016/j.carbpol.2015.01.066. Epub 2015 Feb 7.

PMID:
25843867
42.

Molecular structure studies of (1S,2S)-2-benzyl-2,3-dihydro-2-(1H-inden-2-yl)-1H-inden-1-ol.

Zhang T, Paluch K, Scalabrino G, Frankish N, Healy AM, Sheridan H.

J Mol Struct. 2015 Mar 5;1083:286-299.

43.

Formulation, stability and pharmacokinetics of sugar-based salmon calcitonin-loaded nanoporous/nanoparticulate microparticles (NPMPs) for inhalation.

Amaro MI, Tewes F, Gobbo O, Tajber L, Corrigan OI, Ehrhardt C, Healy AM.

Int J Pharm. 2015 Apr 10;483(1-2):6-18. doi: 10.1016/j.ijpharm.2015.02.003. Epub 2015 Feb 3.

PMID:
25660067
44.

Polymorphism in sulfadimidine/4-aminosalicylic acid cocrystals: solid-state characterization and physicochemical properties.

Grossjohann C, Serrano DR, Paluch KJ, O'Connell P, Vella-Zarb L, Manesiotis P, Mccabe T, Tajber L, Corrigan OI, Healy AM.

J Pharm Sci. 2015 Apr;104(4):1385-98. doi: 10.1002/jps.24345. Epub 2015 Jan 20.

PMID:
25605031
45.

Moisture diffusion and permeability characteristics of hydroxypropylmethylcellulose and hard gelatin capsules.

Barham AS, Tewes F, Healy AM.

Int J Pharm. 2015 Jan 30;478(2):796-803. doi: 10.1016/j.ijpharm.2014.12.029. Epub 2014 Dec 16.

PMID:
25526672
46.

An Acoustic-Based Method to Detect and Quantify the Effect of Exhalation into a Dry Powder Inhaler.

Holmes MS, Seheult JN, O'Connell P, D'Arcy S, Ehrhardt C, Healy AM, Costello RW, Reilly RB.

J Aerosol Med Pulm Drug Deliv. 2015 Aug;28(4):247-53. doi: 10.1089/jamp.2014.1169. Epub 2014 Nov 13.

PMID:
25393346
47.
48.

Solubility of crystalline organic compounds in high and low molecular weight amorphous matrices above and below the glass transition by zero enthalpy extrapolation.

Amharar Y, Curtin V, Gallagher KH, Healy AM.

Int J Pharm. 2014 Sep 10;472(1-2):241-7. doi: 10.1016/j.ijpharm.2014.06.038. Epub 2014 Jun 23.

PMID:
24968139
49.

The acoustic features of inhalation can be used to quantify aerosol delivery from a Diskus™ dry powder inhaler.

Seheult JN, O'Connell P, Tee KC, Bholah T, Al Bannai H, Sulaiman I, MacHale E, D'Arcy S, Holmes MS, Bergin D, Reeves E, Reilly RB, Crispino-O'Connell G, Ehrhardt C, Healy AM, Costello RW.

Pharm Res. 2014 Oct;31(10):2735-47. doi: 10.1007/s11095-014-1371-x. Epub 2014 May 28.

PMID:
24867420
50.

Dry powders for oral inhalation free of lactose carrier particles.

Healy AM, Amaro MI, Paluch KJ, Tajber L.

Adv Drug Deliv Rev. 2014 Aug;75:32-52. doi: 10.1016/j.addr.2014.04.005. Epub 2014 Apr 13. Review.

PMID:
24735676

Supplemental Content

Loading ...
Support Center