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Items: 25


Antibody drug conjugates against the receptor for advanced glycation end products (RAGE), a novel therapeutic target in endometrial cancer.

Healey GD, Pan-Castillo B, Garcia-Parra J, Davies J, Roberts S, Jones E, Dhar K, Nandanan S, Tofazzal N, Piggott L, Clarkson R, Seaton G, Frostell A, Fagge T, McKee C, Margarit L, Conlan RS, Gonzalez D.

J Immunother Cancer. 2019 Oct 29;7(1):280. doi: 10.1186/s40425-019-0765-z.


A RAGE-Targeted Antibody-Drug Conjugate: Surface Plasmon Resonance as a Platform for Accelerating Effective ADC Design and Development.

Healey GD, Frostell A, Fagge T, Gonzalez D, Conlan RS.

Antibodies (Basel). 2019 Jan 7;8(1). pii: E7. doi: 10.3390/antib8010007.


Liquid crystal delivery of ciprofloxacin to treat infections of the female reproductive tract.

Pisano S, Giustiniani M, Francis L, Gonzalez D, Margarit L, Sheldon IM, Paolino D, Fresta M, Conlan RS, Healey GD.

Biomed Microdevices. 2019 Mar 29;21(2):36. doi: 10.1007/s10544-019-0385-x.


Bovine scavenger receptor class A (SR-A) exhibit specific patterns of regulation in the endometrium during the oestrous cycle and early pregnancy.

Vitorino Carvalho A, Eozenou C, Richard C, Forde N, Healey GD, Giraud-Delville C, Mansouri-Attia N, Lonergan P, Sheldon IM, Sandra O.

Reprod Fertil Dev. 2019 Mar 29. doi: 10.1071/RD18411. [Epub ahead of print]


Isoprenoids increase bovine endometrial stromal cell tolerance to the cholesterol-dependent cytolysin from Trueperella pyogenes.

Griffin S, Healey GD, Sheldon IM.

Biol Reprod. 2018 Oct 1;99(4):749-760. doi: 10.1093/biolre/ioy099.


Maternal metabolism affects endometrial expression of oxidative stress and FOXL2 genes in cattle.

Lesage-Padilla A, Forde N, Poirée M, Healey GD, Giraud-Delville C, Reinaud P, Eozenou C, Vitorino Carvalho A, Galio L, Raliou M, Oudin JF, Richard C, Sheldon IM, Charpigny G, Lonergan P, Sandra O.

PLoS One. 2017 Dec 27;12(12):e0189942. doi: 10.1371/journal.pone.0189942. eCollection 2017.


Antibody-drug conjugates and other nanomedicines: the frontier of gynaecological cancer treatment.

Howard D, Garcia-Parra J, Healey GD, Amakiri C, Margarit L, Francis LW, Gonzalez D, Conlan RS.

Interface Focus. 2016 Dec 6;6(6):20160054. Review.


Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis.

Healey GD, Collier C, Griffin S, Schuberth HJ, Sandra O, Smith DG, Mahan S, Dieuzy-Labaye I, Sheldon IM.

J Immunol. 2016 Jan 15;196(2):823-31. doi: 10.4049/jimmunol.1501080. Epub 2015 Dec 16.


Ovarian steroids do not affect bovine endometrial cytokine or chemokine responses to Escherichia coli or LPS in vitro.

Saut JP, Healey GD, Borges AM, Sheldon IM.

Reproduction. 2014 Dec;148(6):593-606. doi: 10.1530/REP-14-0230. Epub 2014 Sep 22.


SOCS genes expression during physiological and perturbed implantation in bovine endometrium.

Carvalho AV, Reinaud P, Forde N, Healey GD, Eozenou C, Giraud-Delville C, Mansouri-Attia N, Gall L, Richard C, Lonergan P, Sheldon IM, Lea RG, Sandra O.

Reproduction. 2014 Dec;148(6):545-57. doi: 10.1530/REP-14-0214. Epub 2014 Sep 3.


Analysis of STAT1 expression and biological activity reveals interferon-tau-dependent STAT1-regulated SOCS genes in the bovine endometrium.

Vitorino Carvalho A, Eozenou C, Healey GD, Forde N, Reinaud P, Chebrout M, Gall L, Rodde N, Padilla AL, Delville CG, Leveugle M, Richard C, Sheldon IM, Lonergan P, Jolivet G, Sandra O.

Reprod Fertil Dev. 2016 Mar;28(4):459-74. doi: 10.1071/RD14034.


Innate immunity and inflammation of the bovine female reproductive tract in health and disease.

Sheldon IM, Cronin JG, Healey GD, Gabler C, Heuwieser W, Streyl D, Bromfield JJ, Miyamoto A, Fergani C, Dobson H.

Reproduction. 2014 Sep;148(3):R41-51. doi: 10.1530/REP-14-0163. Epub 2014 Jun 2. Review.


Development of pre-clinical models for evaluating the therapeutic potential of candidate siRNA targeting STAT6.

Healey GD, Lockridge JA, Zinnen S, Hopkin JM, Richards I, Walker W.

PLoS One. 2014 Feb 27;9(2):e90338. doi: 10.1371/journal.pone.0090338. eCollection 2014.


Differential endometrial cell sensitivity to a cholesterol-dependent cytolysin links Trueperella pyogenes to uterine disease in cattle.

Amos MR, Healey GD, Goldstone RJ, Mahan SM, Düvel A, Schuberth HJ, Sandra O, Zieger P, Dieuzy-Labaye I, Smith DG, Sheldon IM.

Biol Reprod. 2014 Mar 13;90(3):54. doi: 10.1095/biolreprod.113.115972. Print 2014 Mar.


Evaluation of nasal epithelium sampling as a tool in the preclinical development of siRNA-based therapeutics for asthma.

Healey GD, Evans N, Hopkin JM, Davies G, Walker W.

J Cell Mol Med. 2013 Mar;17(3):356-64. doi: 10.1111/jcmm.12014. Epub 2013 Feb 13.


Immunity and inflammation in the uterus.

Turner ML, Healey GD, Sheldon IM.

Reprod Domest Anim. 2012 Aug;47 Suppl 4:402-9. doi: 10.1111/j.1439-0531.2012.02104.x. Review.


Explants of intact endometrium to model bovine innate immunity and inflammation ex vivo.

Borges AM, Healey GD, Sheldon IM.

Am J Reprod Immunol. 2012 Jun;67(6):526-39. doi: 10.1111/j.1600-0897.2012.01106.x. Epub 2012 Feb 13.


RNA interference of STAT6 rapidly attenuates ongoing interleukin-13-mediated events in lung epithelial cells.

Walker W, Healey GD, Hopkin JM.

Immunology. 2009 Jun;127(2):256-66. doi: 10.1111/j.1365-2567.2008.02951.x. Epub 2008 Oct 29.


Administration of antibody to the lung protects mice against pneumonic plague.

Hill J, Eyles JE, Elvin SJ, Healey GD, Lukaszewski RA, Titball RW.

Infect Immun. 2006 May;74(5):3068-70.


Protection against heterologous Burkholderia pseudomallei strains by dendritic cell immunization.

Elvin SJ, Healey GD, Westwood A, Knight SC, Eyles JE, Williamson ED.

Infect Immun. 2006 Mar;74(3):1706-11.


Immunological responses after immunisation of mice with microparticles containing antigen and single stranded RNA (polyuridylic acid).

Westwood A, Elvin SJ, Healey GD, Williamson ED, Eyles JE.

Vaccine. 2006 Mar 10;24(11):1736-43. Epub 2005 Oct 24.


Activation of dendritic cells by microparticles containing Bacillus anthracis protective antigen.

Westwood A, Healey GD, Williamson ED, Eyles JE.

Vaccine. 2005 May 31;23(29):3857-63. Epub 2005 Mar 17.


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