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Items: 17

1.

Circulating matrix metalloproteinases and tissue metalloproteinase inhibitors in patients with idiopathic pulmonary fibrosis in the multicenter IPF-PRO Registry cohort.

Todd JL, Vinisko R, Liu Y, Neely ML, Overton R, Flaherty KR, Noth I, Newby LK, Lasky JA, Olman MA, Hesslinger C, Leonard TB, Palmer SM, Belperio JA; IPF-PRO Registry investigators.

BMC Pulm Med. 2020 Mar 14;20(1):64. doi: 10.1186/s12890-020-1103-4.

2.

Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry.

Todd JL, Neely ML, Overton R, Durham K, Gulati M, Huang H, Roman J, Newby LK, Flaherty KR, Vinisko R, Liu Y, Roy J, Schmid R, Strobel B, Hesslinger C, Leonard TB, Noth I, Belperio JA, Palmer SM; IPF-PRO Registry investigators.

Respir Res. 2019 Oct 22;20(1):227. doi: 10.1186/s12931-019-1190-z.

3.

Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.

Grädler U, Fuchss T, Ulrich WR, Boer R, Strub A, Hesslinger C, Anézo C, Diederichs K, Zaliani A.

Bioorg Med Chem Lett. 2011 Jul 15;21(14):4228-32. doi: 10.1016/j.bmcl.2011.05.073. Epub 2011 May 30.

PMID:
21684157
4.

Inhibition of inducible nitric oxide synthase in respiratory diseases.

Hesslinger C, Strub A, Boer R, Ulrich WR, Lehner MD, Braun C.

Biochem Soc Trans. 2009 Aug;37(Pt 4):886-91. doi: 10.1042/BST0370886. Review.

PMID:
19614613
5.

BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.

Tiso M, Strub A, Hesslinger C, Kenney CT, Boer R, Stuehr DJ.

Mol Pharmacol. 2008 Apr;73(4):1244-53. doi: 10.1124/mol.107.041319. Epub 2008 Jan 4.

PMID:
18178668
6.

In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase.

Lehner MD, Marx D, Boer R, Strub A, Hesslinger C, Eltze M, Ulrich WR, Schwoebel F, Schermuly RT, Barsig J.

J Pharmacol Exp Ther. 2006 Apr;317(1):181-7. Epub 2005 Dec 20.

PMID:
16368897
7.

The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.

Strub A, Ulrich WR, Hesslinger C, Eltze M, Fuchss T, Strassner J, Strand S, Lehner MD, Boer R.

Mol Pharmacol. 2006 Jan;69(1):328-37. Epub 2005 Oct 13.

PMID:
16223957
8.

Evidence for histamine as a transmitter in rat carotid body sensor cells.

Koerner P, Hesslinger C, Schaefermeyer A, Prinz C, Gratzl M.

J Neurochem. 2004 Oct;91(2):493-500.

9.

Tetrahydrobiopterin, a critical factor in the production and role of nitric oxide in mast cells.

Gilchrist M, Hesslinger C, Befus AD.

J Biol Chem. 2003 Dec 12;278(50):50607-14. Epub 2003 Sep 26.

10.

Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.

Zheng JS, Yang XQ, Lookingland KJ, Fink GD, Hesslinger C, Kapatos G, Kovesdi I, Chen AF.

Circulation. 2003 Sep 9;108(10):1238-45. Epub 2003 Aug 18.

PMID:
12925450
11.

Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1-methyl-4-phenylpyridinium in nigral slice cultures.

Madsen JT, Jansen P, Hesslinger C, Meyer M, Zimmer J, Gramsbergen JB.

J Neurochem. 2003 Apr;85(1):214-23.

12.

Glial cell line-derived neurotrophic factor up-regulates GTP-cyclohydrolase I activity and tetrahydrobiopterin levels in primary dopaminergic neurones.

Bauer M, Suppmann S, Meyer M, Hesslinger C, Gasser T, Widmer HR, Ueffing M.

J Neurochem. 2002 Sep;82(5):1300-10.

13.

Development of the pteridine pathway in the zebrafish, Danio rerio.

Ziegler I, McDonald T, Hesslinger C, Pelletier I, Boyle P.

J Biol Chem. 2000 Jun 23;275(25):18926-32. Erratum in: J Biol Chem 2000 Jul 28;275(30):23406. McDonaldo T [corrected to McDonald T].

16.

The glycyl radical enzyme TdcE can replace pyruvate formate-lyase in glucose fermentation.

Sawers G, Hesslinger C, Muller N, Kaiser M.

J Bacteriol. 1998 Jul;180(14):3509-16.

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